role of oxidative stress in development of cardiovascular complications in diabetes mellitus
Báo cáo khoa học: Effect of oxidative stress and involvement of poly(ADP-ribose) polymerase (PARP) in Dictyostelium discoideum development doc
... abnor-mal fruiting bodies with larger fruits.PARP involvement during oxidative stress- induced developmental changes in D. discoideumTo determine the role of PARP in oxidative stress- induced developmental ... PARP inhibitor, on oxidative stress- induced changes in D. discoideum development. Interestingly, oxidative stress resulted in PARPactivation within 5 min that was inhibited by benzamide. Oxidative ... animportant role under oxidative stress [21]; however,there is no report on the role of PARP in D. discoideum development. We have investigated the role of PARP in D. discoideum development by inhibiting...
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Báo cáo sinh học: "Molecular and cellular correlates of the CIITA-mediated inhibition of HTLV-2 Tax-2 transactivator function resulting in loss of viral replication" pot
... residues included in the 253-410region, themselves very weakly interacting with Tax2,may participate in generating the correct conformationfor the critical binding site of the strongly interacting253-1130 ... C,Bertazzoni U, Bex F: Association of HTLV Tax proteins with TAK1-bindingprotein 2 and RelA in calreticulin-containing cytoplasmic structuresparticipates in Tax-mediated NF-κB activation. Virology ... in the inhibition of Tax-2function. Interestingly, in absence of CIITA, endogenousNF-YB can still bind to Tax-2, although, as we have pre-viously shown, this interaction does not results in...
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o cáo hóa học:" Molecular and cellular correlates of the CIITA-mediated inhibition of HTLV-2 Tax-2 transactivator function resulting in loss of viral replication" potx
... residues included in the 253-410region, themselves very weakly interacting with Tax2,may participate in generating the correct conformationfor the critical binding site of the strongly interacting253-1130 ... function.Subcellular distribution of Tax-2 in presence of CIITA In order to obtain a deeper insight into the mechanism of CIITA-mediated inhibition on Tax-2 function, thesubcellular distribution of Tax-2 molecules ... in the inhibition of Tax-2function. Interestingly, in absence of CIITA, endogenousNF-YB can still bind to Tax-2, although, as we have pre-viously shown, this interaction does not results in...
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Báo cáo lâm nghiệp: "Improving RBS estimates – effects of the auxiliary variable, stratification of the crown, and deletion of segments on the precision of estimate" pps
... 0.6/0.8 Mountain ash 0 0.2 0.4 0.6 0.8 1.0 0.2/04 0.2/06 0.2/0.8 0.4/0.6 0.4/0.8 0.6/0.8 Cutting-points on main stem Cutting-points on main stemFig. 10. Coefficient of variation (n = 1) of the target ... Deletion of great sized segments yielded higher precision in almost all cases. Stratification of the crown was not generally successful in terms of a reduction of sampling errors. Only in combination ... 2003). (In the fol-lowing, we write qi instead of q1, qij instead of q2, and so on, in order to indicate the units selected on each stage: unit i on stage 1, unit j on stage 2 within the...
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Tài liệu Báo cáo khoa học: Enhancement of oxidative stress-induced apoptosis by Hsp105a in mouse embryonal F9 cells pptx
... important role in protection of neuronal cellsagainst stress- induced apoptosis [26]. In accordance withthese findings, ischemia/reperfusion in the rat forebraininduces the expression of HSP105/110 ... activation of p38 induced by oxidative stress, we further examined whether its activationis responsible for the induction of apoptosis in F9 cells usingSB202190, a potent inhibitor of p38. As shown in ... mitogen-activated protein kinase(p38). Furthermore, oxidative stress- induced apoptosis wassuppressed by SB202190, a potent inhibitor of p38, in F9cells. These findings indicated that the activation of p38...
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Ambient particulate air pollution induces oxidative stress and alterations of mitochondria and gene expression in brown and white adipose tissues ppt
... 8:20http://www.particleandfibretoxicology.com/content/8/1/20Page 8 of 14 inflammatory response and IR development, were exam-ined in mice. As shown in Figure 3, PM2.5exposureinduced a marked increase in macroph age (F4/80+cells)infiltration in eWAT. ... effect of ambient PM2.5onWATandBATspecificgenesindifferent adipose depots. There are several major find-ings in this study. First, exposure to PM2.5resulted in oxidative stress in BAT. ... expression in iBAT(Relative to FA)FAPM2.5ABFigure 4 Immunohistochemical examination of uncoupling protein 1 (UCP1) in the iBAT. A. iBAT was stained by antibody against UCP1 andcounterstained...
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báo cáo hóa học: " The microglial NADPH oxidase complex as a source of oxidative stress in Alzheimer''''s disease" ppt
... use of vitamin E and vitamin C in combi-nation reduced the prevalence and incidence of AD in anelderly population; however, the use of either of thesevitamins alone had no effect [110]. Finally, ... complex leads to theinitiation of complex signaling events leading to proteintyrosine phosphorylation and activation of the src-familykinases Lyn and Fyn as well as the tyrosine kinase Syk[30,32,52]. ... inhibition of phosphati-dylinositol-3 kinase (PI3K) attenuates ROS production.These findings suggest that these kinases are involved in upstream signaling cascades responsible for activatingNADPH...
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báo cáo hóa học: " Biomarkers of oxidative stress and its association with the urinary reducing capacity in bus maintenance workers" pptx
... response of the organism to particle-induced oxida-tive stress. The observed increase of reducing species in urine would mirror an increased level in blood originat-ing from a response to oxidative ... only 10% of urate is excreted in the urine (theremaining 90% being recirculated by the renal system[3]), an increase of this antioxidant in blood will alsolead to an increase in urine. The ... beenreported to increase the serum levels of uric acid in North Carolina police officers [4]. A similar increase of plasma antioxidants in response to an increased oxid a-tive stress was observed in newborns...
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ROLE OF THE ADIPOCYTE IN DEVELOPMENT OF TYPE 2 DIABETES potx
... Cytokine-mediated modulation of leptin and adiponectin secretion during in vitro adipogenesis: evidence that tumor necrosis factor-α- and interleukin-1β treated Role of the Adipocyte in Development ... impair insulin signaling through activation of protein kinase C θ (PKCθ). PKCθ phosphorylates insulin receptor substrate I, thus preventing the phosphorylation involved in the insulin signal ... the Adipocyte in Development of Type 2 Diabetes 16effects (Tang et al., 2001), acting as co-adjuvants in the reduction of the incident of diabetes (Doggrell, 2002), increasing vascular function...
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The effects of oxidative stress on female reproduction: a review ppt
... regulator of proper development and remodeling. Angiogenic factors areknown to play key roles in the maintenance of properspiral artery remodeling. Thus, the involvement of uterine NK cells in RPL ... Durak I: Role of oxidative stress in intrauterine growth restriction. Gynecol Obstet Invest2007, 64:187–192.228. Karowicz-Bilinska A: Lipid peroxides concentration in women withintrauterine growth ... JG: Role of oxidative stress in endometriosis. Reprod Biomed Online 2006, 13:126–134.22. Agarwal A, Gupta S, Sharma RK: Role of oxidative stress in femalereproduction. Reprod Biol Endocrinol...
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a comparative analysis of the cognitive moral development of independent public auditors in selected public accounting firms and bank examiners in selected federal banking regulatory agencies
... Reproduced with permission of the copyright owner. Further reproduction prohibited without permission. Reproduced with permission of the copyright owner. Further reproduction ... without permission. Reproduced with permission of the copyright owner. Further reproduction prohibited without permission. Reproduced with permission of the copyright owner. Further reproduction ... without permission. Reproduced with permission of the copyright owner. Further reproduction prohibited without permission. Reproduced with permission of the copyright owner. Further reproduction...
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Báo cáo hóa học: " Predictors of quality of life: A quantitative investigation of the stress-coping model in children with asthma" pptx
... asthma within the context of other predictors. With this study a first step is made in investigating predictors of HRQoL while taking other pre-dictors in account. Since most studies investigate ... stress- coping model in total [9-11]. In a sample of adult heart patients, tentative proof was found for themodel in total [9,10]. Moreover, Röder et al. [11] investi-gated this stress- coping model in ... stress- coping model. While the stress- coping model has often been used as a frame of reference in studying health related quality of life in chronic illness, few have actually tested the model in children...
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