... 3College of Pharmacy, TianJin Medical University, Tianjin, 300070, PR China AbstractTo develop pullulan acetate nanoparticles (PANs) as a drug nanocarrier, pullulan acetate (PA) was synthesized and ... Tianjin, Tianjin 300192, PR China. Tel/Fax: +86 22 87890868. E-mail: zhangqiq@126.comRESEARCH ARTICLE Stability and in vivo evaluation of pullulan acetate as a drug nanocarrier Hong-Bo Tang1, ... storage stability of PANs was studied in the aqueous medium, and the acute toxicity of PANs was evaluated in mice. Morever, EPI was loaded into PANs and its pharmacokinetics was also assessed...