Báo cáo y học: " Factor correction as a tool to eliminate between-session variation in replicate experiments: application to molecular biology and retrovirology" ppsx

... purposes)RetrovirologyOpen AccessResearch Factor correction as a tool to eliminate between-session variation in replicate experiments: application to molecular biology and retrovirologyJan M Ruijter*1, ... molecular- biology data set from Figure 1 A: original data. B: normalised data. C: standardised data. D: data after factor correction. Note that normalisation, standardisation, and fac-tor correction ... nn=−().2Comparison of normalisation, standardisation and factor cor-rectionFigure 2Comparison of normalisation, standardisation and factor correction. Mean (and SEM) of the data of the molecular- biology...

Báo cáo y học: " Tracheal agenesis as a rare cause of difficult intubation in a newborn with respiratory distress: a case report" pdf

... and renaldefects. Tracheal agenesis can be a manifestation of sev-eral syndromes such as VATER (vertebrae, anus, trachea,esophagus, and renal), also known as VACTERL, and TARCD (total alkaloids ... immobile vocal cords lying in the mid-line position. Other findings are a cleft between thearytenoids, as well as associated congenital anomalies.Good oxygenation may be maintained with bag-maskventilation ... fetal anomalies. During birth, the baby may not cry ormay have a weak cry. An acute severe respiratory distressdevelops and multiple attempts at intubations fail. Laryn-goscopy will reveal...

Báo cáo Y học: Protein methylation as a marker of aspartate damage in glucose-6-phosphate dehydrogenase-deﬁcient erythrocytes docx

... proteins,catalysed by PCMT, is increased as erythrocytes age in thecirculation [6,25,26]. This has been related to an increasednumber of abnormal aspartate residues, spontaneouslyarising fromL-asparaginyl ... fromL-asparaginyl deamidation and/ orL-aspartylisomerization reactions [7]. In addition it has been reportedthat isoaspartate residues, detected by the PCMT in situassay, increase in membrane ... 2035isomerization of aspartate residues [6]. Major targets ofthese alterations, also called Ôprotein molecular fatiguedamageÕ [7], are cytoskeletal components, such as ankyrin and bands 4.1 and 4.2, as...

Báo cáo y học: "B cells as a therapeutic target in autoimmune disease" doc

... drug-resistant human B cell lymphomas to thecytotoxic effect of CDDP, VP1- and toxins [abstract]. FASEB J1995, 9 :A2 06.8. Kosmas C, Stamatopoulos K, Stavroyianni N, Tsavaris N,Papadaki T: Anti-CD20-based ... rheumatoid factor can crosslink Fcγ (crystallizable fragment gamma)receptors. However, in contrast to the animal model,neither for rheumatoid factor nor for any of the otherautoantibodies in RA ... still has anaccepted role in thrombotic thrombocytopenic purpura and cryoglobulinemia; however, in other chronic inflamma-tory diseases, plasmapheresis has had disappointingresults. After 1980,...

Báo cáo y học: "Rheumatoid arthritis as a hyper-endoplasmic reticulumassociated degradation disease" pdf

... thatCommentaryRheumatoid arthritis as a hyper-endoplasmic reticulum-associated degradation diseaseSatoshi Yamasaki1, Naoko Yagishita1, Kaneyuki Tsuchimochi1, Kusuki Nishioka2 and Toshihiro Nakajima11Department ... 41:1995-2003.11. Amano T, Yamasaki S, Yagishita N, Tsuchimochi K, Shin H, Kawa-hara K, Aratani S, Fujita H, Zhang L, Ikeda R, et al.:Synoviolin/Hrd1, an E3 ubiquitin ligase, as a novel pathogenic factor ... between syno+/+ and syno+/−mice. No advancedsynovial cell hyperplasia was detected in CIA-syno+/−mice,even though inflammatory cell infiltration was clearly observed in them. Detailed analysis...

Báo cáo y học: "Plasma gelsolin as a biomarker of inflammation" doc

... exposed at the site ofoverwhelming injury may act as a sink to exhaust the supply ofplasma gelsolin, in turn allowing redundant inflammatorycascades unfettered opportunity to wreak havoc uponmultiple ... Identified ligands include platelet-activating factor, lysophosphatidic acid, and sphingosine 1phosphate, as well as cell-wall constituents of Gram-negative and Gram-positive bacteria [6-8]. Actin exposed ... as a cytoplasmic actin-regulatory proteinessential for cell locomotion and phagocytosis. When a circulating isoform was subsequently discovered, its physio-logical significance was far from apparent.For...

Báo cáo y học: "Urinary TWEAK as a biomarker of lupus nephritis: a multicenter cohort study" potx

... samples. All assays were performedblindly, without knowledge of the patient's identity, diseasepresence or disease activity.Assay standardization To take into account variations in urine concentration,uTWEAK ... longitudinal study, although uTWEAK levels didincrease as the flare approached, the peak was at the time ofthe flare rather than in advance of it. As the measurementswere based on a relatively small ... follow-up and surveil-lance and often entailing changing treatments. A number ofbiochemical markers are currently used to clinically assesspatients' disease activity, such as anti-double-stranded...

Báo cáo y học: " Toxoplasmosis presenting as a swelling in the axillary tail of the breast and a palpable axillary lymph node mimicking malignancy: a case report" potx

... this article as: Siriwardana et al.: Toxoplasmosis presenting as a swelling in the axillary tail of the breast and a palpable axillary lymphnode mimicking malignancy: a case report. Journal of ... presenting as a swelling in theaxillary tail of the breast and a palpable axillarylymph node mimicking malignancy: a case reportHP Priyantha Siriwardana1*, Louise Teare2, Dia Kamel3 and E ... Inwang1AbstractIntroduction: Lymphadenopathy is a common finding in toxoplasmosis. A breast mass due to toxoplasmosis isvery rare, and only a few cases have been reported. We present a case...

Báo cáo y học: " Axial torsion as a rare and unusual complication of a Meckel’s diverticulum: a case report and review of the literature" ppsx

... MD, and the diag nosis is usuallymade intra-operatively. Major risk factors for torsionappear to include an increased size of the MD with a narrow base, potentially compromising blood supply and ... encompassed within the vascular terri-tory of the inflamed, unhealthy, and friable mesentery.An end -to- end seromuscular, single-layered anastomosisusing a 4-0 synthetic absorbable suture, was ... patient had normal renalfunction and a normal hemoglobin level. An abdominalradiograph revealed dilated small bowel loops, and a clinical diagnosis of perforated acute appendici tis wasmade....

Báo cáo y học: " Exploring mentorship as a strategy to build capacity for knowledge translation research and practice: protocol for a qualitative study" pps

... regional healthauthorities and hospitals in Canada. Social Science and Medicine2006, 62:964-76.28. Lomas J: Using 'linkage and exchange' to move research intopolicy at a Canadian foundation. ... Hospital, Toronto, Canada and 9General Internal Medicine, St. Michael's Hospital, Toronto, CanadaEmail: Anna R Gagliardi* - anna.gagliardi@uhnresearch.ca; Laure Perrier - l.perrier@utoronto.ca; ... Buckingham JM, Zhang Y, Craft P, Dahlstrom JE, Tait N, etal.: Surgical management of invasive breast cancer: a 5-yearprospective study of treatment in the Australian CapitalTerritory and South-Eastern...

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