hormone responsible for lowering blood sugar by promoting the movement of glucose to body cells is
Promoting the Use of End-to-End Congestion Control in the Internet pptx
... it is the basis for our approach in thispaper for defining flows using a disproportionate share of the 2This particular form of evasion of end -to- end congestion control wouldbe reduced by the ... and the packet drop rate for conformantTCP. For our simulations we set to 12,000, which is close to for bytes and seconds.Limitations of this Test: Gauging the level of unsatisfieddemand is ... link; this wouldlimit the appropriateness of this test to those routers where the propagation delay of the attached link is likely to be a signifi-cant fraction of the end -to- end delay of a connection’s...
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Tài liệu Báo cáo khoa học: Is ATP binding responsible for initiating drug translocation by the multidrug transporter ABCG2? docx
... multidrug efflux pumps is assumed to correspond to the outward-facing confor-mation. The energy produced by the hydrolysis of ATP is harnessed for the resetting of the transporter to the initial high-affinity, ... withinNBDs. The best evidence for an interaction between the two domains is the ability of numerous substratesand modulators of ABCG2 (and the R482G isoform) to stimulate the rate of ATP hydrolysis [21,24,25],albeit ... binding conformation. By inference,therefore, the step in the catalytic cycle corresponding to the release of inorganic phosphate ([Pi]) is likely to correspond to the restoration of a high-affinityconformation...
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Tài liệu Produced jointly by the British HIV Association (BHIVA), the British Association for Sexual Health & HIV (BASHH) and the Faculty of Family Planning & Reproductive Health Care doc
... prophylaxis is the ability of the patients to adhere to the regimen. Such individuals are often psychologically vulnerable and relatively intolerant of side effects. Therefore, the choice of drugs is ... If there is evidence of tubal blockage the couple are advised to have IVF with washed sperm. If the semen analysis is poor then ICSI is advised. IVF and ICSI outcome is not affected by the ... are to minimise the risk of viral transmission to the uninfected partner and future child and ensure the safety of healthcare workers and other patients attending the fertility centre. The risks...
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Tài liệu Báo cáo khoa học: The ubiquitin ligase Itch mediates the antiapoptotic activity of epidermal growth factor by promoting the ubiquitylation and degradation of the truncated C-terminal portion of Bid ppt
... Bcl-2family involved in the initiation of apoptosis through the mitochondrial pathway. The key event in the mito-chondrial pathway is the release of proapoptotic fac-tors from the mitochondrial intermembrane ... apoptosis. The mitochondrial release of cytochrome c and second mitochondria-derivedactivator of caspase (Smac ⁄ DIABLO) allows for the formation of the apoptosome, a complex that enables the activation ... EGF is at least partly due to JNK acti-vation. If this is the case, then the protective effect of EGF on TRAIL-induced apoptosis should also dependon JNK activity. To test this hypothesis,...
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Tài liệu Báo cáo khoa học: "Inducing Gazetteers for Named Entity Recognition by Large-scale Clustering of Dependency Relations" ppt
... Allreduce, to sum up localZ of the all cluster nodes and to set Z with the resulting sum. We can computep(cl|vti, ni) by using this Z to normalize the value.Although the above is the essence of ... sentences) of Wikipedia articles and then usedthem as a gazetteer for NER. We used this method to construct the Wikipedia gazetteer. The method described by Kazama and Torisawa(2007) is to first ... created by usingsuch richer semantic/syntactic structures improves the accuracy for NER. The size of the gazetteers is also a novel point of this study. The previous studies, with the excep-tion of...
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Báo cáo hóa học: "TAp73 is one of the genes responsible for the lack of response to chemotherapy depending on B-Raf mutational status" pot
... target genes of p53 andtheir respective TAp73 isoforms [6]. Therefore, the TAisoforms may be expected to have functions in tumorsuppression while ΔN isoforms might be oncogenic. For the first ... genes [5]. These different isoforms havebeen shown to have vastly different activities. The TAisoforms act similarly to p53, inducing apoptosis. Incomparison, ΔN isoforms have little transactivationactivity ... geneticdetermining factors of the action mechanism of EGFR-targeted therapies in colorectal cancers (CRCs) is impor-tant at least for two reasons. F irst, the under standing of the molecular basis of therapies...
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Diffusing all by pattern - the reading of saintly lives
... the Motto to be Read.An Hand still open to relieve the Poor,And by Dispersing to increase the Store.(Verse ) By extending a heraldry of grace, Mather opposes the “false Heraldry” of wit ... in this final section is virtually indistinguishable from other The reading of saintly lives I sing the , by Heav’ns peculiar Grace, The Prince of Prophets, of the Chosen Race,Rais’d ... affirmation of peace. Yet Taylor could not have missedtheir precise echo of the words spoken by the Shunammite’s son, whowas stricken in the fields and then raised by Elisha ( Kings :). It is impossible...
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Tài liệu Carrots, Sticks, and Promises: A Conceptual Framework for the Management of Public Health and Social Issue Behaviors docx
... when the risk premium is low to moderate, marketing-basedexchanges can compensate for the cost of the risk, when it is too high, law often is needed because the manager is unable to compensate for ... with the proffered choice. In general, the presence of a reinforcer is incentive (marketing), whereas the withholding of a reinforcer or the onset of a punishment is coercive (backed by the force ... Related to the preceding proposition is the perceived share of the commu-nity cost imposed on, and the benefit to be garnered by, the individual. The greater the perception of a payoff, the easier...
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Tài liệu Báo cáo khoa học: Gene transcription of fgl2 in endothelial cells is controlled by Ets-1 and Oct-1 and requires the presence of both Sp1 and Sp3 pdf
... this gene is controlled by Ets-1 and requires the presence both of the Sp1 and Sp3 transcription factors. The presence of this complex multicomponent PRD in the fgl2proximal promoter is consistent ... sufficient for the basal expression of the fgl2 gene. This finding is consistent with the observation that fgl2 is constitutivelyexpressed in cultured endothelial cells, as well as in the primary endothelial ... way to the beginning of ATG start codon to avoid the discrepancy of minor transcription start variance between macrophagesand endothelial cells. Endothelial cells transiently transfectedwiththelongestfragmentofthe5Â-fgl2...
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Báo cáo khoa học: Induction of PPARb and prostacyclin (PGI2) synthesis by Raf signaling: failure of PGI2 to activate PPARb potx
... medullaryinterstitial cells is reduced by overexpression of PPARband further decreased upon administration of cPGI[16]. In apparent contrast to these observations is the finding that the ectopic expression of ... tumorigenesis [17] and promotes apoptosis[3]. The interpretation of these studies is, however,complicated because there is no definitive proof thatnatural PGI2 is a PPARb agonist and other potentialPPARb ... this finding,PPARb transcriptional activity was affected neither by the pharmacological inhibition of PGI2synthesis nor by the simultaneous overexpression of Cox-2 andPGIS. Our data therefore...
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corporate social responsibility strategies for sustainable development for small and medium enterprises in the village of bac ninh province, vietnam
... expansion of the unit to be effective. The mission of the enterprises in the villages: - To maintain the traditional products in the marketplace. - To maintain the prestige of the business to the ... innovation to improving the ability to adapt to the trend of sociaty is one of the leading principles in today’s business world. During the renovation of the country, Vietnam has faced to many ... groups - to create strategic ; the dependence of the distribution; the corporation, the factory is mainly engaged in large packages, the situation ought not to stiff competition. Form two: The...
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DYING TO BE MEN: Psychosocial, Environmental, and Biobehavioral Directions in Promoting the Health of Men and Boys pptx
... are the biggest contributors to their increased risk for disease, injury, and death. But this is not to suggest that the problem is simply a matter of men “behaving badly.” In fact, it is a ... reassuring throughout the process of authoring this work. I’m also indebted to my editors at Taylor and Francis, Dana Bliss and Christopher Tominich, for their guidance in shepherding this project from ... Furthermore, there is consistent evidence that the lack of social support constitutes a risk factor for mortality—especially for men. Men with the lowest levels of social support are 2 to 3...
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Achieving Effective Social Protection For All In Latin America And The Caribbean - From Right To Reality doc
... implemented—often in crisis situations—with the goal of ameliorating the effects of unemployment. The main targeting mechanismin this case is the self-selection of those willing to work for the offered ... protection—which is enshrined in the consti-tutions and laws of most LAC countries—into a reality for the majority of their populations. At the heart of this predicament is the very low cov-erage of contributory ... case, the amount of subsidydepends (inversely) on the value of the contributory pension to which the person is entitled. The EMTR is 100 percent: For each unit increasein the contributory pension,...
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Báo cáo khoa học: Rapamycin inhibits lipopolysaccharide induction of granulocyte-colony stimulating factor and inducible nitric oxide synthase expression in macrophages by reducing the levels of octamer-binding factor-2 doc
... treatment was for 6 h, then the G-CSF protein levels in the medium were determined by ELISA. The values for the LPS-treated cells were divided by those for the non-LPS-treated cells and are shown ... concentration of G-CSFprotein in the medium was measured by ELISA (B). The values for the LPS-treated cells were divided by those for the non-LPS-treated cells and are shown as a percentage of the values ... this effect is blocked by a PI3K, Akt or mTOR inhibitor.(A) THP-1 cells were induced to differentiate by exposure to 160 nM PMA for 24 h and then incubated with or without LPS for 6 h in the...
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Báo cáo khoa học: Structural determinants of protein stabilization by solutes The importance of the hairpin loop in rubredoxins pdf
... the sequence of RdDg) and their spatial positioning enablethem to pack together, thereby preventing exposure of the metal centre to solvent water. The hydrophobiccluster created by these residues is ... severe disruption of the middle loop, the rest of the characteristic features of the protein structure remained virtually unchanged asshown by the small RMSD value of 0.82 A˚obtained for the superimposition ... for some of these residues (Fig. 3).In particular, the exposure of the residues that com-prise the lower part (relative to the orientation depic-ted in Fig. 2) of the hydrophobic core of the...
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- hormone responsible for increasing blood calcium levels
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