which hormone is responsible for lowering blood sugar after consuming cho
Báo cáo khoa học: A characteristic Glu17 residue of pig carnitine palmitoyltransferase 1 is responsible for the low Km for carnitine and the low sensitivity to malonyl-CoA inhibition of the enzyme docx
Ngày tải lên :
16/03/2014, 04:20
... carnitine: 1 mm (for standard comparison with
other published data), and a concentration equal to
the K
m
for carnitine of each enzyme (for comparison
between mutants). In this article, we show ... sequence as being responsible for the pecu-
liar kinetic characteristics of this enzyme, acting as a
negative determinant for malonyl-CoA sensitivity.
Asp17 may account, at least in part, for the high
degree ... nat-
urally occurring variation, Glu17, is responsible for both the low malonyl-
CoA sensitivity and high carnitine affinity characteristics of the pig enzyme.
This is the first demonstration that a single...
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Báo cáo khoa học: A novel factor XI missense mutation (Val371Ile) in the activation loop is responsible for a case of mild type II factor XI deficiency doc
Ngày tải lên :
23/03/2014, 07:20
... active conformation, Val371 forms contacts
with neighboring residues that are important for stabi-
lizing the active state (e.g. Asp189, which is part of the
S1 pocket responsible for the binding ... substitution of Val371 to
isoleucine might prevent the full development of the
active conformation. This hypothesis is further con-
firmed by the results of FIX proteolytic assays, which
showed a slight ... sequence identity of 30–45%), this
position is occupied solely by a valine. This conserved
amino acid is replaced by isoleucine in the Val371Ile
FXI mutant. Interestingly, an isoleucine residue natu-
rally...
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Báo cáo khoa học: Direct CIII–HflB interaction is responsible for the inhibition of the HflB (FtsH)-mediated proteolysis of Escherichia coli r32 by kCIII docx
Ngày tải lên :
23/03/2014, 10:20
... factor that favors lysogeny and is
responsible for primary control of the lambda develop-
mental decision for lysis or lysogeny [4,7–9]. In the
absence of CIII, CII is rapidly degraded by the ATP-
dependent ... proteolysis of r
32
by different
concentrations of CIII or CIIIC. The bands corresponding to r
32
-C-
his (1.2 l
M) remaining after proteolysis with GST–HflB (0.8 lM) for
40 min in the presence of His
6
–CIII ... However, this proteolysis is much
slower in vitro, because of a lack of chaperone machin-
ery. The in vitro proteolysis requires ATP [14]. We
examined the proteolysis of purified r
32
-C-his (1.2...
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Báo cáo khoa học: Cdk2 activity is dispensable for triggering replicon initiation after transient hypoxia in T24 cells docx
Ngày tải lên :
16/03/2014, 23:20
... after medium renewal; 5Â,
reoxygenated for 5 min after 7 h hypoxic incubation; 30Â, reoxygen-
ated for 30 min after 7 h hypoxic incubation.
Cdk2 is dispensable for replicon initiation D. Stabenow ... renewal; 5Â, reoxy-
genated for 5 min after 7 h hypoxic incubation; 30Â, reoxygenated
for 30 min after 7 h hypoxic incubation.
D. Stabenow et al. Cdk2 is dispensable for replicon initiation
FEBS ... bound Cdc6 is high at the end of the hyp-
oxic period and distinctly decreases within 30 min after
reoxygenation. The remainder is apparently converted
into the slower migrating form. This significant
decrease...
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Tài liệu Báo cáo khoa học: Is ATP binding responsible for initiating drug translocation by the multidrug transporter ABCG2? docx
Ngày tải lên :
18/02/2014, 18:20
... prior to hydrolysis. The low-affinity state was
observed to be retained immediately post-hydrolysis. Therefore, the dissoci-
ation of phosphate and ⁄ or ADP is likely to be responsible for resetting
of ... high-affinity
conformation for the transporter, which is supported
by the restoration of high-affinity binding in the ADP-
bound conformation. That this step of the catalytic
cycle is associated ... of ATP
per se is the ‘power stroke’ for drug translocation, and
that energy obtained from the hydrolysis process is
used to reset the transporter. That ATP binding is
responsible for the shift...
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Tài liệu Báo cáo Y học: Interallelic recombination is probably responsible for the occurrence of a new as1-casein variant found in the goat species potx
Ngày tải lên :
22/02/2014, 04:20
... subsequently distin-
guished after a second amplification which allows discrim-
ination between the alleles on the basis of the f ragment sizes
(Fig. 8 , Step IIA).
In the first step, a 266-bp (265 bp for ... first one is an ACRS-PCR technique [26], the principle
of which is to create a TaqI restriction site (TCGA) by using
a mismatching primer (C9LM*) which allows both the F
and M alleles to be discriminated ... 715/18 795/18 875 Da (18 555 Da after a lkaline phos-
phatase hydrolysis), corresponding to that expected for the
F variant. This result is the first evidence for the heterozy-
gous status (M/F)...
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In order to become competent in a foreign language, it is important for language learners not only to acquire new vocabularies and a new set of phonological and syntactic rules but also to learn what Wilson (1986)
Ngày tải lên :
17/04/2013, 16:09
... văn ở đây tạo
điều kiện cho động thực vật sinh sôi nảy nở, thích hợp cho việc phát triển nguồn
sinh vật trên cạn và dưới nước, thuận lợi cho canh tác nông nghiệp, cho phát
triển thuỷ hải sản.
-19-
... Định danh đã thể hiện khả năng tư duy
của con người, giúp ích cho tư duy của con người. “Tri giác cảm tính cho ta sự
vật, lí tính cho ta tên gọi sự vật” [55; 88].
Con người tạo ra ngôn ngữ bằng ...
lịch sử, phong tục, tập quán xưa của một cộng đồng người.
-34-
dưới lực ép, không cho trỗi dậy, không cho nổi lên” của “dằn” [65; 236]) trong
PNNB…
Những gì được con người nhận thức giống...
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Which Sound Is Different?
Ngày tải lên :
26/06/2013, 01:25
... bronchitis B. chestnut C. chronometer D. chrisma
8. A. chauvinism B. exchange C. teacher D. childrearing
9. A. bristle B. indict C. Connecticut D. Vinci
10. A. scherzo B. scholar C. school D. ...
4. A. ought B. bough C. thought D. brought
5. A. spoor B. door C. floor D. force
6. A. poisonous B. noise C. tortoise D. buoy
7. A. golf B. adulthood C. wood D. bosom
8. A. wool B. mood C. took ... happy D. plane
6. A. drama B. aroma C. apology D. parliament
Bảo Thoa 1
AN ANSWER KEY IS NOT WISHED FOR!
Bảo Thoa 7
1. A. inversion B. permanent C. clerk D. derby [Br. E]
2. A. teach B....
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Which Sound Is Different?
Ngày tải lên :
27/06/2013, 11:46
... bronchitis B. chestnut C. chronometer D. chrisma
8. A. chauvinism B. exchange C. teacher D. childrearing
9. A. bristle B. indict C. Connecticut D. Vinci
10. A. scherzo B. scholar C. school D. ... special
2. A. character B. cart C. chemistry D. chimney
3. A. society B. social C. cellar D. proceed
4. A. chain B. choice C. choir D. chocolate
Bảo Thoa 2
WHICH SOUND IS DIFFERENT?
These tests will ...
4. A. ought B. bough C. thought D. brought
5. A. spoor B. door C. floor D. force
6. A. poisonous B. noise C. tortoise D. buoy
7. A. golf B. adulthood C. wood D. bosom
8. A. wool B. mood C. took...
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