hormone responsible for increasing blood calcium levels
Flavor enhancement as a tool for increasing pleasantness and intakeof a snack product among the elderly
... given differentinformation on the samples for the home-use. One group inboth age cohorts was informed about the organic quality ofthe sample and another group received information aboutthe ... presence of health-related information. Since the effectsof information were negligible, and not relevant enough for this study, the data were pooled together over theinformation conditions.Olfactory ... effects tested were aromaconcentration of the sample (two levels) and the session (two levels, before and after the home-use). Age group (two levels) was used as a between-subject factor. These statisticalanalyses...
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Tài liệu Investigation of Organic Chemicals Potentially Responsible for Mortality and Intersex in Fish of the North Fork of the Shenandoah River, Virginia, during Spring of 2007 ppt
... others (in press).HormonesFour common natural and synthetic hormones were targeted in this study. Extracts selected for hormone analy-sis required derivatization of the hormones to facilitate ... held for 3 minutes, then ramped at 9 °C/min to 320 °C and held at 320 °C for 3 minutes. Identification of the targeted chemicals was performed using full-scan MS, and quantification was performed ... with the Friends of the North Fork of the Shenandoah RiverInvestigation of Organic Chemicals Potentially Responsible for Mortality and Intersex in Fish of the North Fork of the Shenandoah River,...
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Tài liệu Báo cáo khoa học: Identification of two late acyltransferase genes responsible for lipid A biosynthesis in Moraxella catarrhalis doc
... except for UDP-GlcNAc acyltransferase, responsible for lipid A biosynthesis inM. catarrhalis, have been identified. By bioinformatics, two late acyltrans-ferase genes, lpxX and lpxL, responsible for ... m HCl at 80 °C for 18 h.The FAMEs were recovered into the organic phase bythree-fold extraction with 50% NaCl ⁄ chloroform (1 : 1v ⁄ v). A new volume of chloroform was used for each ofthe ... LpxM is responsible for the addition of a secondary myristate(C14:0) chain at the 3¢-position of lipid A [36,37]. InH. influenzae, the htrB (lpxL) gene product was shownto be responsible for the...
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Tài liệu Báo cáo khoa học: Is ATP binding responsible for initiating drug translocation by the multidrug transporter ABCG2? docx
... post-hydrolysis. Therefore, the dissoci-ation of phosphate and ⁄ or ADP is likely to be responsible for resettingof the transporter. The data indicate that, like ABCB1 and ABCC1,the ‘power stroke’ for translocation ... inform on the orientation of the sites,only their affinity for interaction with drugs.The data presented here suggest that the ABC-G2R482Gisoform undergoes the following sequence ofconformational ... ABCB1, the R482G isoformalso contains multiple sites of interaction for a singledrug (daunomycin), which can manifest as homotropicallostery [22]. The latter has been observed for thebacterial...
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Tài liệu Báo cáo khoa học: Functional studies of active-site mutants from Drosophila melanogaster deoxyribonucleoside kinase Investigations of the putative catalytic glutamate–arginine pair and of residues responsible for substrate specificity docx
... analmost 2000-fold decrease in the kcatvalue for dThd,and a 270-fold decrease for dCyd. The Kmvalue wasincreased sevenfold for dThd and 49-fold for dCyd.The large decrease in kcatvalue ... catalytic rate. For the E52Dmutant the Kmvalue was approximately the same as for the wild-type with dThd, whereas kcatwas 20 000times lower. This was also the scenario for the E52Hmutant ... ordered with formation ofa ternary complex [1,2]. Pre-steady-state measurementsindicate that either the catalytic step or a precedingstep is rate determining for the overall forward reac-tion...
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Tài liệu Báo cáo khoa học: A novel coupled enzyme assay reveals an enzyme responsible for the deamination of a chemically unstable intermediate in the metabolic pathway of 4-amino-3-hydroxybenzoic acid inBordetellasp. strain 10d doc
... pathways for 3-hydroxyanth-ralinic acid differs from that in the pathway for 4-amino-3-hydroxybenzoic acid.The N-terminal amino acid sequence of the purifiedenzyme d id not show significant levels ... coupled assay wasidentified as 2-hydroxymuconic 6-semialdehyde by GC-MSanalysis. A mechanism for the formation of 2-hydroxy-muconic 6-semialdehyde via enzymatic deamination andnonenzymatic decarboxylation ... characterization of theenzymes is slow [2,4], p robably because the substrate for the enzyme assay, 2-aminomuconic 6 -semialdehyde, which i sformed by ring cleavage of 2-aminoph enol, is unstable and isconverted...
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Tài liệu Báo cáo Y học: Interallelic recombination is probably responsible for the occurrence of a new as1-casein variant found in the goat species potx
... & M artin [6], we also n eeded to obtaininformation ab out relevant noncoding regions in whichspecific and informative mutations are localized. For these reasons, we d ecided to analyse the ... M/B).Interestingly, the mutation s pecific for the M allele affectsthe same nucleotide as that which is deleted in the F allele,and shown to be responsible for the internal deletion of 37amino-acid ... ollowingthree-step cycle which was repeated 35 times: denaturation for 30 s (or 1 min) at 94 °C, annealing for 30 s (or 2 min) at47–60 °C, and extension for 30–60 s (or 3 min) at 72 °C,using the 2400 (or...
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Báo cáo khoa học: Identification of the structural determinant responsible for the phosphorylation of G-protein activated potassium channel 1 by cAMP-dependent protein kinase pdf
... determinant responsible for PKAphosphorylation in vitroTo identify the structural determinants that are respon-sible for phosphorylation of GIRK1 by PKA, fusionproteins comprising truncated forms ... mmolÆL)1glutathione pH 8.0.Immunoprecipitation For the immunoprecipitation experiments, Xenopus laevisoocytes were injected with cRNAs coding for GIRK1 andGIRK4 (5 ng per oocyte for each RNA) and the KHA2antisense ... proteinwas also demonstrated to be a direct target for PKA-catalysed phosphorylation [17,22,23]. Despite severalefforts undertaken to identify the responsible structuraldeterminant on the GIRK1...
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Báo cáo khoa học: Two short protein domains are responsible for the nuclear localization of the mouse spermine oxidase l isoform pdf
... nuclear localization for the mSMOl isoform (Fig. 4).Taken together, these results consistently substanti-ate the hypothesis that these two structural regions aremandatory for the nuclear localization ... (2005) 3052–3059 ª 2005 FEBSTwo short protein domains are responsible for the nuclearlocalization of the mouse spermine oxidase l isoformMarzia Bianchi1, Roberto Amendola2, Rodolfo Federico1, ... neuroblastoma cell line, N18TG2, to investi-gate its subcellular localization. Augmented transcript levels for each recombinant protein were detected intransiently transfected neuroblastoma cells, using...
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Báo cáo Y học: Identification and characterization of a new gene from Variovorax paradoxus Iso1 encoding N -acyl-D-amino acid amidohydrolase responsible for D-amino acid production pdf
... strain Iso1 was V. paradoxus .For example, the stain Isol was positive for catalase, oxidase andnitrate reduction but negative of hydrolysis for gelatin andstarch. Therefore, according to all above ... incubated at 37 °C overnight. The transformantswere screened for enzyme activity by adding to each well10 lL2mgÆmL)1lysozyme and incubating at 37 °Cfor30 min. This was followed by the addition ... mea-surements were performed at various temperatures for 20 min. Thehighest activity was taken as 100%. (B) Thermostability of purifiedenzyme. The purified enzyme was preincubation for 30 min at varioustemperatures....
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Báo cáo khoa học: The gene carD encodes the aldehyde dehydrogenase responsible for neurosporaxanthin biosynthesis in Fusarium fujikuroi potx
... WÆm)2 for different times beforemycelia filtration. For carotenoid analysis of the strainsused in the expression experiments, incubations were per-formed for 7 days in the dark at 22 °C. For ... to light for 15 min, 30 min, 1 h, or 2 h. Relative levels arereferred to the maximal value determined in the wild type in thelight. All data show averages and standard deviations for four mea-surements ... fujikuroi were formerly investigated in N. crassa (al-1[20], al-2 [21,22], and cao-2 [23], respectively).Recently, we identified in this fungus the gene ylo-1[24], which is responsible for the aldehyde...
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Báo cáo khoa học: A characteristic Glu17 residue of pig carnitine palmitoyltransferase 1 is responsible for the low Km for carnitine and the low sensitivity to malonyl-CoA inhibition of the enzyme docx
... scale) for IC50calculation. The Km for carnitine was obtained by assayingmitochondria in the presence of increasing carnitine concen-trations: 50–1500 lm for pig CPTIB, and 50–2000 l m for human ... the single amino acid variation observedbetween pig and human (Asp17 for human and Glu17 for pig) might be responsible for the kinetic charac-teristics of both CPT1B enzymes. Consequently, ... sequence as being responsible for the pecu-liar kinetic characteristics of this enzyme, acting as anegative determinant for malonyl-CoA sensitivity.Asp17 may account, at least in part, for the highdegree...
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Báo cáo Y học: Monitoring the structural consequences of Phe12 fi D-Phe and Leu15 fi Aib substitution in human/rat corticotropin releasing hormone Implications for design of CRH antagonists pdf
... index,3JHNHa,andu vs. w plots, Fig. S2) imply aconformational preference for an extended structure. Theunambiguous conformational preference for helical struc-ture for the C-terminal 10-peptide is manifested ... values for a-helix structure, while wangles for Leu14 and Arg16 are considerably close to therange of values for 310helix. Additionally, Leu14 possess a utorsion angle almost typical for the ... the backbone conformational freedom [47–49]. Thislimitation is imposed by the steric hindrance that arises fromits gem-dimethyl group. The torsion angles for the main-chain conformation of Aib15...
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Báo cáo khoa học: TioS T-TE – a prototypical thioesterase responsible for cyclodimerization of the quinoline- and quinoxaline-type class of chromodepsipeptides potx
... thiocoraline, the sulfhydryl groups of l-Cys3form a disulfide crossbridge minimizing conforma-tional freedom to a great extent. It can be assumedthat the oxidative formation of the crossbridge is car-ried ... biosynthesis, an oxidoreductase (Ecm17) isfound within the biosynthetic operon proposed to be responsible for disulfide formation [35]. This oxidore-ductase, although lacking in the gene cluster enablingthiocoraline ... The lack ofN-methylation of l-Cys3 ⁄ 4 is presumably responsible for the absence of DNA-bisintercalation activity.N-methylation induces conformational changes andelevates rotational barriers...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose