efficient unsupervised discovery of word categories
Tài liệu Báo cáo khoa học: "Computationally Efficient M-Estimation of Log-Linear Structure Models∗" doc
... inside,and outside of noun phrases. Each state emits atag and a word (independent of each other given thestate). We replaced the first occurrence of every tagand of every word in the training ... theperformance of the HMM and test different estima-tion methods, we use Sha and Pereira’s feature tem-plates, which include subsequences of labels, tags,and words of different lengths and offsets. ... the minimization of (w) as a way of training a log-linear model.4 Algorithms for Models of Sequences andTreesWe discuss here some implementation aspects of theapplication of M-estimation...
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Báo cáo khoa học: "Unsupervised Discovery of Rhyme Schemes" pdf
... 2011.c2011 Association for Computational Linguistics Unsupervised Discovery of Rhyme SchemesSravana ReddyDepartment of Computer ScienceThe University of ChicagoChicago, IL 60637sravana@cs.uchicago.eduKevin ... extremely useful forlarge-scale statistical analyses of poetic texts.• Historical Linguistics/Study of DialectsRhymes of a word in poetry of a given timeperiod or dialect region provide clues ... repetition of rhymes,and have made no assumptions about word pronun-ciations. Therefore, the algorithm’s performanceis strongly correlated4with the predictability of rhyming words. For writing...
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Tài liệu Báo cáo khoa học: Efficient killing of SW480 colon carcinoma cells by a signal transducer and activator of transcription (STAT) 3 hairpin decoy oligodeoxynucleotide – interference with interferon-c-STAT1-mediated killing pdf
... potentia-tion of the pro-apoptotic effect of doxorubicin wasfound, whereas inhibition of STAT3 with a dominantnegative or a platinum derivative increased thepro-apoptotic effect of doxorubicin ... doxorubicin [43]. Thus, theefficiency of blocking STAT3 may depend onthe absence of the inhibition of STAT1. Indeed, celldeath induced by ODN and by IFN-c may be theresult of completely different mechanisms. ... increased bymore than twofold (Fig. 6B). In the absence of IFN-ctreatment, there was a low but clearly detectablephosphorylation of STAT3. Finally, to analyse theinteraction of both STAT1 and STAT3...
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Tài liệu Báo cáo khoa học: Reversible tetramerization of human TK1 to the high catalytic efficient form is induced by pyrophosphate, in addition to tripolyphosphates, or high enzyme concentration ppt
... Hofstee plot of the data.B. Munch-Petersen Enzymatic regulation of human TK1FEBS Journal 276 (2009) 571–580 ª 2008 The Author Journal compilation ª 2008 FEBS 577Reversible tetramerization of ... pathway of deoxy-ribonucleotide metabolism, catalyzing the first step in the synthesis of dTTP by transfer of a c-phosphate group from a nucleoside triphosphateto the 5¢-hydroxyl group of thymidine, ... co-operativity as indicated by con-cave Hofstee plots of v versus v ⁄ s (insets to the kineticplots), Hill coefficients < 1 and high K0.5values(Table 1). All of the tetrameric forms showed approxi-mately...
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Tài liệu Báo cáo khoa học: The role of N-glycosylation in the stability, trafficking and GABA-uptake of GABA-transporter 1 Terminal N-glycans facilitate efficient GABA-uptake activity of the GABA transporter pptx
... terminaltrimming of N-glycans is involved in the regulation of the stability and trafficking of GAT1. It has beenreported that a variety of molecular chaperones andfolding enzymes assist the folding of newly ... membrane traffick-ing and reduced stability of the N-glycosylationmutants of GAT1 must be a result of misfolding of these proteins.The deficiency of N-glycosylation results in a mark-edly reduced ... normalized for the surface pro-tein of these mutants. Double N-glycosylation mutantsshowed a marked reduction of GABA-uptake activity of 60–40% of that of the wild type. GAT-mediatedGABA transport...
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Tài liệu Báo cáo khoa học: Efficient RNA ligation by reverse-joined hairpin ribozymes and engineering of twin ribozymes consisting of conventional and reverse-joined hairpin ribozyme units ppt
... reaction, the oxygen atom of the free 5¢-OHgroup of one RNA fragment attacks the phosphorous of the cyclic 2¢,3¢-phosphate group of another, result-ing in ligation of the two fragments. In contrast ... beprocessed, such that variation of the distance betweenthe two sites seems reasonable only at this stage.In summary, the demonstration of functionality of HP–TWRJ provides proof of the principle that, ... Because of the specific hairpin ribozyme cleavage–ligation charac-teristics described above a fragment of residingsequence is removed in the first part of the reactionfollowed by binding of another...
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Báo cáo khoa học: A novel mechanism of V-type zinc inhibition of glutamate dehydrogenase results from disruption of subunit interactions necessary for efficient catalysis doc
... enzyme.Titrations of enzyme alone and enzyme in the presence of 20 mM glutamate, together with equivalent titrationsin the presence of 100 lM zinc and control titrations of NADPH in the absence of enzyme, ... observed.Effects of zinc on the stability of the enzymeThe thermal stability of the enzyme was determinedusing differential scanning calorimetry in the presenceand absence of zinc under a variety of conditions. ... wavelength of 340 nm and an emission wave-length of 450 nm, were performed in the presence of vari-ous combinations of 100 lM zinc acetate and 20 mMglutamate as well as in the absence of other...
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Báo cáo khoa học: Efficient and targeted delivery of siRNA in vivo pdf
... transport of macromoel-cules > 5 nm in diameter is significantly inhibited innormal tissues [36]. However, transport of macromole-cules across the tumor endothelium is more efficient than that of ... FEBSMINIREVIEW Efficient and targeted delivery of siRNA in vivoMin Suk Shim1and Young Jik Kwon1,2,31 Department of Chemical Engineering and Materials Science, University of California, Irvine, ... California, Irvine, CA, USA2 Department of Pharmaceutical Sciences, University of California, Irvine, CA, USA3 Department of Biomedical Engineering, University of California, Irvine, CA, USAIntroductionRNA...
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Báo cáo khoa học: "Exploring Deterministic Constraints: From a Constrained English POS Tagger to an Efficient ILP Solution to Chinese Word Segmentation" ppt
... features of a word. Endings or prefixes of English words donot deterministically mark their morphological in-flections. We propose to compute the morph feature of a word as the set of all of its ... corresponding word count features of possible words that are composed of the boundary and contextual characters of wi. Thespecific word- based feature templates are illustratedin the second row of Table ... sequence cto the set of all possible segmentations of c. Forexample, w = (c1 cl1) (cn−lk+1 cn) represents asegmentation of k words and the lengths of the firstand last word are l1and...
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Báo cáo khoa học: "Efficient Optimization of an MDL-Inspired Objective Function for Unsupervised Part-of-Speech Tagging" docx
... agood start). In Proceedings of the ACL.S. Goldwater and T. L. Griffiths. 2007. A fullyBayesian approach to unsupervised part -of- speechtagging. In Proceedings of the ACL.M. Hyder and K. Mahata. ... minimize the size of the model simultane-ously. We define the size of a model as the number of non-zero probabilities in its parameter vector.Let θ1, . . . , θnbe the components of θ. We wouldlike ... Optimization of an MDL-Inspired Objective Function for Unsupervised Part -of- Speech TaggingAshish Vaswani1Adam Pauls2David Chiang11Information Sciences InstituteUniversity of Southern...
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Báo cáo khoa học: "Unsupervised Learning of Acoustic Sub-word Units" pot
... to ML-SSS.4.2 Unsupervised Learning of Sub -word UnitsWe used about 30 minutes of phonetically tran-scribed Japanese speech from one speaker6providedby Maekawa (2003) for our unsupervised ... concurrently and efficiently.Choosing the best subset of splits from among theseis then cast as a constrained knapsack problem, towhich an efficient solution is devised. Another con-tribution of this ... eigen-vector of Σsand 0 < 1 is typically 0.2.3. Re-estimate all parameters of this (overgrown)HMM. Gather the Gaussian sufficient statisticsfor each of the 4N states from the last pass of re-estimation:...
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Báo cáo khoa học: Efficient inhibition of b-secretase gene expression in HEK293 cells by tRNAVal-driven and CTE-helicase associated hammerhead ribozymes doc
... preclearing process of thecell protein extract (100 lg of protein in 500 lLofextract) was carried out as described above. Immuno-precipitation and determination of the intracellular level of Ab40 was ... of the BACE mRNA level because of the lowerexpression of ribozyme. A similar profile of the targetmRNA was obtained for the cells transfected with the Rz-2plasmid (data not shown).Effect of ... level of extra- and intracellular release of b-amyloid peptide, which is a product of the catalyticactivity of the target protein. Our efforts to use Western blotanalysis for detection of the...
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Báo cáo khoa học: A new and efficient method for inhibition of RNA viruses by DNA interference pptx
... deprived of the 2¢-OH group of ribose. We showed the silencing effect of targetedRNA in HeLa cells to be at the level of approximately78% when 100 nm siDNA was used (Fig. 2). Applica-tion of higher ... slightly less efficient than inthe case of dsRNA, and a higher dose of siDNA isrequired for efficient silencing, dsDNA shows highercellular stability than dsRNA. The other advantages of ABFig. ... phases of RNAi. Ago proteinsare key components of RISC responsible for the cleav-age of the target RNA. The cleavage is catalysed by aPiwi domain of Ago proteins, the structural homolog of RNase...
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- efficient method of moments
- efficient method of moments emm
- renewable and efficient electric power systems
- the discovery of mexico
- unsupervised recognition of literal
- effects of word confusion
- efficient inference of crfs
- efficient handling of uncertainty
- efficient unsupervised discovery of word categories
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