Mild cognitive impairment is associated with falls among older adults findings from the irish longitudinal study on ageing (TILDA)

Mild cognitive impairment is associated with falls among older adults findings from the irish longitudinal study on ageing (TILDA)

Mild cognitive impairment is associated with falls among older adults  findings from the irish longitudinal study on ageing (TILDA)
... ACCEPTED MANUSCRIPT Mild cognitive impairment is associated with falls among older adults: findings from the Irish Longitudinal Study on SC R IP T Ageing (TILDA) Stefanos Tyrovolas1,2, ... IP T The prevalence of mild cognitive impairment was 10% in the Irish older population Mild cognitive impairment is related with higher rates of falls among older adults Mild cognitive impairment ... this study was to evaluate the IP association between MCI and number of falls or occurrence of non-accidental falls SC R among older adults Methods: Data from the first wave of the Irish longitudinal...
  • 24
  • 28
  • 0

Báo cáo khoa học: Muramyl-dipeptide-induced mitochondrial proton leak in macrophages is associated with upregulation of uncoupling protein 2 and the production of reactive oxygen and reactive nitrogen species docx

Báo cáo khoa học: Muramyl-dipeptide-induced mitochondrial proton leak in macrophages is associated with upregulation of uncoupling protein 2 and the production of reactive oxygen and reactive nitrogen species docx
... correlating the uncoupling effect induced by these molecules with the level and function of UCP2 and free radical production in macrophages We find that MDP induces reactive oxygen and nitrogen species ... effects on the UCP2 modulates MDP-induced mitochondrial inefficiency central nervous system, and the lack of induction of in ammatory responses [22 ] Despite a long-standing interest in the field of muramyl ... (3.6-fold, P < 0.05) On the other hand, analysis of the kinetics of induction of UCP2 protein in MDP-treated macrophages revealed a significant increase starting h after stimulation (2. 2-fold, P < 0.05),...
  • 11
  • 162
  • 0

Báo cáo y học: "Mannose-binding lectin deficiency is associated with early onset of polyarticular juvenile rheumatoid arthritis: a cohort study" pdf

Báo cáo y học:
... determined by studying six 'extended' genotype groups: YA/YA, YA/XA, XA/XA, YA/O, XA/O and O/O Statistical analysis Data are presented as median and IQR because clinical and laboratory variables were ... XA/O and O/O Individuals with YA/YA and YA/XA haplotypes have high or normal MBL levels Therefore, patients can be classified into high (YA/YA and YA/XA), medium (XA/XA and YA/O) and low (XA/O ... citation purposes) bility to JRA and whether MBL2 genotypes are associated with severity of JRA, as assessed based on patient characteristics and disease variables Materials and methods Patients...
  • 11
  • 162
  • 0

Báo cáo y học: "Early drotrecogin alpha (activated) administration in severe sepsis is associated with lower mortality: a retrospective analysis of the Canadian ENHANCE cohort" ppsx

Báo cáo y học:
... confidence interval; DrotAA = Drotrecogin alfa activated readily available variables may be potential early clinical predictors of outcome, and that, when indicated, early rather than late administration ... that continued or worsening coagulopathy during the first day of severe sepsis was associated with new organ failure and increased mortality at 28 days [18] Data from an integrated sepsis database ... trial and have had direct input into the drafting, revisions, and final approval of this manuscript BL was responsible for statistical analysis, and HF had direct input into the drafting, analysis, ...
  • 10
  • 57
  • 0

Accounting for Changes in Social Support Among Married Older Adults: Insights From the MacArthur Studies of Successful Aging pptx

Accounting for Changes in Social Support Among Married Older Adults: Insights From the MacArthur Studies of Successful Aging pptx
... by their friends and relatives The men’s social support increased over time for all types of support from all sources The women’s social support increased over time for all types of support from ... result in the loss of support In fact, although the number of reported social ties decreased over time, the amount of emotional and instrumental support reported, for the most part, increased These ... in social support Changes in Social Support The present study extends previous work on the dynamic nature of support (e.g., Antonucci, 1991) On the positive side, to the extent that the pruning...
  • 10
  • 133
  • 0

báo cáo khoa học: " Trends in beliefs about the harmfulness and use of stop-smoking medications and smokeless tobacco products among cigarettes smokers: Findings from the ITC four-country survey" pdf

báo cáo khoa học:
... article as: Borland et al.: Trends in beliefs about the harmfulness and use of stop-smoking medications and smokeless tobacco products among cigarettes smokers: Findings from the ITC four-country ... trends in beliefs about the harmfulness of nicotine itself, stop-smoking medication including NRT, and SLT over the last to years in Canada, the US, the UK and Australia This paper also examines ... McNeill A, Borland R, Hammond D, King B, Boudreau C, Cummings KM: Smokers’ beliefs about the relative safety of other tobacco products: findings from the ITC collaboration Nicotine & Tobacco Research...
  • 11
  • 63
  • 0

Báo cáo y học: " A Novel Variable Number of Tandem Repeat of the Natriuretic Peptide Precursor B gene’s 5’-Flanking Region is Associated with Essential Hypertension among Japanese Females"

Báo cáo y học:
... region of < /b> the < /b> type A < /b> human natriuretic < /b> peptide < /b> receptor gene and association analysis using a < /b> novel < /b> microsatellite in essential hypertension Am J Hypertens 1999; 12: 1144-8 26 Takahashi Y,< /b> Nakayama ... Germany) Int J Med Sci 2007, Statistical analysis Data are presented as the < /b> mean ± SD The < /b> Hardy-Weinberg equilibrium was assessed by doing chi-square (χ2) analysis Differences in the < /b> clinical data ... and its association with essential hypertension and left ventricular hypertrophy in the < /b> Japanese Circ Res 2000; 86: 841-5 13 Nakayama T, Soma M, Rahmutula D, Ozawa Y,< /b> Kanmatsuse K Isolation of...
  • 7
  • 152
  • 1

báo cáo hóa học: "Quantitative gait analysis under dual-task in older people with mild cognitive impairment: a reliability study" doc

báo cáo hóa học:
... Gait variability under single and dual tasks for the six gait variables assessed at baseline Gait variability under single and dual tasks for the six gait variables assessed at baseline viduals ... falls in older adults[8], walking while performing a secondary task (dual-task paradigm) has become a classic way to assess the relationship between cognition and gait Because the dual-task paradigm ... future falls[8] In our sample of people with Mild Cognitive Impairment, gait variability significantly increased under dual-task conditions While gait variability is minimal under dual-task conditions...
  • 6
  • 143
  • 0

báo cáo hóa học: " Peripheral reductive capacity is associated with cognitive performance and survival in Alzheimer''''s disease" potx

báo cáo hóa học:
... (dashed line) initial AOC levels with Cumulative survival of patients with Alzheimer's disease with low (solid line) and high (dashed line) initial AOC levels Low and high AOC levels were defined ... and of its capacity to cope with inflammatory and oxidative insults The lower levels of peripheral AOC observed in AD patients is also consistent with the finding of lower oxidative resistance of ... measuring their peripheral AOC and to examine the association between AOC levels, the severity of cognitive impairment, and patient survival We found that serum AOC is reduced in AD patients and is...
  • 6
  • 134
  • 0

Báo cáo y học: " The COMTval158met polymorphism is associated with symptom relief during exposure-based cognitive-behavioral treatment in panic disorder" ppt

Báo cáo y học:
... contradictory findings This study aimed at transfering the experimental results of the COMTval158met polymorphism on extinction into a clinical setting by investigating the efficacy of CBT (in particular ... Lonsdorf et al.: The COMTval158met polymorphism is associated with symptom relief during exposure-based cognitivebehavioral treatment in panic disorder BMC Psychiatry 2010 10:99 Submit your next manuscript ... depending on the COMTval158met polymorphism Further, we can exclude the possibility that this differential treatment response may be driven by the met/met group having tendentially lower anxiety symptom...
  • 9
  • 77
  • 0

Báo cáo y học: "Tight perioperative glucose control is associated with a reduction in renal impairment and renal failure in non-diabetic cardiac surgical patients" ppsx

Báo cáo y học:
... Implementing tight glycemic control is associated with an increased risk of hypoglycemia A recent meta-analysis in critically ill patients has demonstrated that intensive insulin therapy is associated ... contributions All authors actively participated in this study, read the manuscript and attest to the validity and legitimacy of the data and its interpretation Key messages • In non-diabetic cardiac surgical ... requiring dialysis [3,5-7] In cardiac surgery poor intraoperative glycemic control in diabetics is associated with a sevenfold increase in postoperative renal failure, whereas severe hyperglycemia...
  • 12
  • 57
  • 0

Gait initiation time is associated with the risk of multiple falls—a population based study

Gait initiation time is associated with the risk of multiple falls—a population based study
... in the community Therefore, in a population- based sample of older people the aims of this study were to examine whether: 1) overall GI time or its components were associated with falls 2) GI time ... 2.73) Discussion In this population- based study of older community-dwelling people, slower overall GI time under single and dual-task was associated with increased risk of multiple falls The strength ... independent of other physiological or psychological falls risk measures In the majority of cases the addition of these other measures did not change the associations between GI and multiple falls The...
  • 6
  • 21
  • 0

Báo cáo y học: "Elevated plasma homocysteine is positively associated with age independent of C677T mutation of the methylenetetrahydrofolate reductase gene in selected Egyptian subjects"

Báo cáo y học:
... Tsai MY C677T and A1298C polymorphisms of the methylenetetrahydrofolate reductase gene: incidence and effect of combined genotypes on plasma fasting and post-methionine load homocysteine in vascular ... Kruyssen DA The 677C >T mutation in the methylenetetrahydrofolate reductase gene: associations with plasma total homocysteine levels and risk of coronary atherosclerotic disease Atherosclerosis ... Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease Am J Hum Genet 1996;58(1):35-41...
  • 12
  • 168
  • 0

Tài liệu Báo cáo khoa học: The splicing factor ASF/SF2 is associated with TIA-1-related/ TIA-1-containing ribonucleoproteic complexes and contributes to post-transcriptional repression of gene expression doc

Tài liệu Báo cáo khoa học: The splicing factor ASF/SF2 is associated with TIA-1-related/ TIA-1-containing ribonucleoproteic complexes and contributes to post-transcriptional repression of gene expression doc
... of gene expression As each step of the RNA metabolism is tightly regulated, the regulation of mRNA export, stability and translation rate is essential for the control of the expression of mRNAs ... localized in the UTRs of the transcript and the trans-acting factors (RNA-binding proteins and noncoding regulatory RNAs) that bind to these sequences Among the best studied regulatory sequences, the ... of the reporter protein fused with the full-length ASF ⁄ SF2 protein, or with the RRM1 alone Most likely, this difference is partly a result of the absence of the RS domain that contributes to...
  • 19
  • 219
  • 0

Xem thêm