what weather is associated with stratocumulus clouds
Báo cáo y học: " A Novel Variable Number of Tandem Repeat of the Natriuretic Peptide Precursor B gene’s 5’-Flanking Region is Associated with Essential Hypertension among Japanese Females"
Ngày tải lên :
26/10/2012, 10:04
...
region of the NPPB gene was discovered. This poly-
morphism was associated with EH in female subjects.
However, this finding does not necessarily imply that
there is a relationship between the ... accession
number AB265677). This VNTR polymorphism is a
tandem repeat of the 4-nucleotide sequence TTTC (Fig.
1A). There were 8 alleles of this VNTR polymorphism,
ranging from 9-repeat to ... a
deletion of this gene develop disorders that resemble
the symptoms of subjects with a deleted allele in the
5’-untranslated region of NPRA. We previously iso-
lated a missense mutation of...
- 7
- 612
- 1
Tài liệu Báo cáo khoa học: The splicing factor ASF/SF2 is associated with TIA-1-related/ TIA-1-containing ribonucleoproteic complexes and contributes to post-transcriptional repression of gene expression doc
Ngày tải lên :
16/02/2014, 15:20
... be associated with
polysomes. Although the association of DDX21 with
TIAR relies on RNA intermediate, DDX5, hnRNP M
and ASF ⁄ SF2 are associated with TIAR by protein–
protein interaction. It is ... molecular
processes. However, the physiological existence of
ASF ⁄ SF2-TIA complexes is conditioned by the tissue
distribution of TIA protein [46], which is clearly more
restricted compared to ASF ⁄ ... acting synergistically
for optimal interaction with RNA, both RRMs mediate
interactions with distinct motifs present in mRNA mol-
ecules addressed to SGs upon stress. ASF ⁄ SF2 is a
bona fide...
- 19
- 666
- 0
Tài liệu Báo cáo khoa học: Down-regulation of heme oxygenase-2 is associated with the increased expression of heme oxygenase-1 in human cell lines docx
Ngày tải lên :
19/02/2014, 05:20
... HO-2
expression with each of two different siRNAs is consis-
tently associated with increased expression of HO-1
mRNA and protein. Moreover, we provide evidence
that at least three mechanisms may account ... cells with HO-2 siRNA induced the expres-
sion of HO-1 mRNA and protein without affecting
the concentration of GAPDH mRNA and b-actin
(Fig. 4A,B). Likewise, the selective reduction of HO-2
mRNA with ... underlined is an artificial
HindIII site. A full-length HO-2 cDNA fragment was iso-
lated from pCR-hHO-2-1 with EcoR1 and subcloned into
the pMACS4-IRES vector (Miltenyi Biotec Inc., Bergisch-
Gladbach,...
- 14
- 487
- 0
Báo cáo khoa học: Muramyl-dipeptide-induced mitochondrial proton leak in macrophages is associated with upregulation of uncoupling protein 2 and the production of reactive oxygen and reactive nitrogen species docx
Ngày tải lên :
05/03/2014, 23:20
... iden-
tical to those of the unstimulated cells. This view is
consistent with a previous report showing that MDP,
but not a safe analogue such as MB, is capable of
inducing mitochondrial proton leak ... purine
nucleotides [4]. UCP2 is widely expressed in many tis-
sues with high levels detected in the spleen, thymus,
pancreatic b-cells, heart, lung, white and brown adi-
pose tissue, stomach, testis and macrophages, ... MDP. The question raised at
this stage is whether UCP2 is responsible for the
increase in mitochondrial proton permeability (state 4)
induced in macrophages after stimulation with MDP.
Purine nucleotides...
- 11
- 430
- 0
Báo cáo khoa học: Cellular refractoriness to the heat-stable enterotoxin peptide is associated with alterations in levels of the differentially glycosylated forms of guanylyl cyclase C pdf
Ngày tải lên :
08/03/2014, 08:20
... long-term
treatment of cells with ST. As the 130 kDa form of GC-C is
still on the surface after prolonged ST treatment, it is not
clear at this time whether the 130 kDa form alone is
recycled, or not ... cells with ST at 4 °C
suggest that down-regulation is brought about by selective
internalization of the 145 kDa form through endocytosis
and subsequent degradation. The mechanisms involved in
this ... 20-day-old
Caco2 cells were washed with serum-free DMEM/F12 and
incubated with or without 10
)7
M
SThinDMEM/F12for
9 h. Monolayers were then washed and re-stimulated with
fresh STh (10
)7
M
) in the...
- 10
- 427
- 0
Báo cáo khoa học: N-Methylation in polylegionaminic acid is associated with the phase-variable epitope of Legionella pneumophila serogroup 1 lipopolysaccharide pptx
Ngày tải lên :
08/03/2014, 10:20
... stereoisomerism). The lower-đeld
1
H NMR signal of 3 belonged to the N-methyl group at N
2
in the E isomer and t he higher-đeld signal t o that in t he
Z isomer, in which N
1
is in trans and cis ... stereoisomers,
E and Z, with regard to the partial double bond at N
2
, while
the NMR spectra showed the presence of only one isomer.
Molecular modelling data ( not shown) suggested t hat this
isomer ... an
(N,N-dimethylacetimidoyl)amino group is presen t (Fig. 8,
structure 2). This group is linked to C5 of a legionaminic
acid residue, which is substituted with a nonmethylated
N-acetimidoyl group...
- 13
- 434
- 0
Báo cáo khoa học: Suppression of urokinase receptor expression by bikunin is associated with inhibition of upstream targets of extracellular signal-regulated kinase-dependent cascade pptx
Ngày tải lên :
17/03/2014, 11:20
... reported that bikunin expression is
associated with a less malignant phenotype [24]. There is
evidence that bikunin significantly prevented pulmonary
metastasis of mouse Lewis lung carcinoma 3LL cells ... sodium vanadate
is associated with increased uPAR expression: bikunin has
no ability to inhibit overexpression of uPAR in cells treated
with sodium vanadate, indicating that bikunin is able to
suppress ... analysis.
(B) Unstimulated cells were treated with PD098059 (60 l
M
) or vehicle for 12 h. C, Cells were pretreated with staurosporin (50 n
M
), PD098059
(60 l
M
), U0126 (20 l
M
), or with a...
- 13
- 314
- 0
Báo cáo khoa học: The unique pharmacology of the scorpion a-like toxin Lqh3 is associated with its flexible C-tail pdf
Ngày tải lên :
23/03/2014, 09:20
... Whereas substitutions of
His15, His36 and His43 did not reduce Lqh3 sensitiv-
ity to pH, substitutions of His66 had a clear impact
with the utmost decrease obtained with H66R
(Table 3). Unexpectedly, ... onto the oocyte, suggesting that Lqh3
sensitivity to pH is associated with some later stage in
the binding process to the channel. This is corrobor-
ated by previous binding studies, which demonstrated
that ... 6B).
Discussion
Insight into the molecular basis of preferential interac-
tions of scorpion a-toxins with insect or mammalian
Na
v
s was thus far obtained mainly from mutagenesis
and comparison...
- 14
- 206
- 0
Báo cáo khoa học: A distinct sequence in the adenine nucleotide translocase from Artemia franciscana embryos is associated with insensitivity to bongkrekate and atypical effects of adenine nucleotides on Ca2+ uptake and sequestration pdf
Ngày tải lên :
29/03/2014, 00:20
... untreated with ADP
than in those treated with the nucleotide. This is in line
with the experimental findings on Ca
2+
uptake capacity
in the presence and absence of adenine nucleotides.
Mitochondria isolated ... rotein
sequence with that of other species (Xenopus, Drosophila,
mouse isoforms 1, 2, and 4, rat isoforms 1 and 2,
bovine isoforms 1, 2, 3, and 4, and human isoforms 1,
2, 3, and 4) is shown in Fig. ... failed to inhibit
ANT operation as compared with the control (5 mm
NH
4
OH, which is the vehicle of BKA, trace c). With
the same BKA stocks, this poison fully inhibited ANT
operation in rat liver...
- 15
- 505
- 0
Báo cáo khoa học: Homologous desensitization of guanylyl cyclase A, the receptor for atrial natriuretic peptide, is associated with a complex phosphorylation pattern pot
Ngày tải lên :
29/03/2014, 09:20
... top). This suggests that this
phosphorylation site, in contrast with the others, is
phosphorylated during homologous desensitization.
Hence, homologous desensitization of GC-A is associ-
ated with ... also
included in all subsequent purifications. After incubation
with lysis buffer for 30 min on ice with vigorous vortexing,
the cell debris and nuclei were pelleted by centrifugation at
2000 g for ... by incubation with anti-FLAG IgG coupled
to agarose beads (M2 agarose, Sigma-Aldrich) for 2 h at
4 °C, followed by extensive washing with Tris buffer. The
protein was eluted in Tris buffer containing...
- 14
- 313
- 0
Báo cáo khoa học: Mutation of epidermal growth factor receptor is associated with MIG6 expression docx
Ngày tải lên :
30/03/2014, 01:20
... hormone administration. For the tran-
scriptional analysis, cells were incubated with 10 nm EGF
for 0.5, 1, 2, 4, 6 or 10 h and then washed twice with
NaCl ⁄ Pi. Cells not treated with growth ... non-
small-cell lung cancer (NSCLC) cell line H1299 with
EGFR overexpression (wild-type: EGFR-WT) and
with or without the mutation in which Leu858 is
substituted with Arg (mutant: L858R), in addition to
the ... RALT is known to be a transcriptional feed-
back regulator of the ErbB-MAPK signaling pathway
[14,15] and its loss is associated with ErbB2 ⁄ HER-2
oncogenic potency leading to Herceptin resistance
[16]....
- 13
- 347
- 0
báo cáo hóa học:" Higher percentage of CD133+ cells is associated with poor prognosis in colon carcinoma patients with stage IIIB" pptx
Ngày tải lên :
18/06/2014, 15:20
... function
of CD133 is unknown, preliminary evidence proposed
that expression of CD133 is associated with the activation
of stemness-related signal pathway, resistance to apopto-
sis and bioenergetic ... cells is
associated with the prognosis of cancer patients, the over-
population hypothesis would be substantially supported.
By now, the relationship between the percentage of
CD133 and prognosis ...
tumor cells and
the prognosis of colorectal cancer patients. This study
showed that the percentage of CD133
+
tumor cells was
associated with the prognosis among patients with locally
advanced colon...
- 8
- 550
- 0
báo cáo hóa học:" A MIF haplotype is associated with the outcome of patients with severe sepsis: a case control study" pdf
Ngày tải lên :
18/06/2014, 15:20
... Kaczmar-
ski EB, Borrow R, Wilson AG: The tumor necrosis factor poly-
morphism TNF (-308) is associated with susceptibility to
meningococcal sepsis, but not with lethality. Crit Care Med
2009, 37:1237-1243.
... characteristics of patients with severe sepsis and patients with abdominal surgery without signs of infection or
inflammation (* unpaired t test, ** Fisher's exact test).
Severe Sepsis
(n ... pol-
ymorphism with inflammatory bowel disease in Chinese Han
population. Cytokine 2008, 41:44-47.
28. Hizawa N, Yamaguchi E, Takahashi D, Nishihira J, Nishimura M:
Functional polymorphisms in the...
- 8
- 554
- 0
Báo cáo hóa học: " Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer" ppt
Ngày tải lên :
18/06/2014, 16:20
... assisted with
the data collection and helped draft the manuscript. IBJ assisted with the
statistical analysis. JM assisted with data collection and helped to draft the
manuscript. JB assisted with ... expression
was associated with a significantly improved OS in uni-
variate and multivariate analysis. This is in line with
previous findings from two independent breast cancer
cohorts where RBM3 was associated ... found to be associated with a
good prognosis in both cohorts. RBM3 expression was
also examined in vitro using the cisplatin sensitive
ovarian cancer cell line A2780 and its cisplatin resistant
derivative...
- 12
- 531
- 0
Báo cáo hóa học: " MMP-1 is a (pre-)invasive factor in Barrettassociated esophageal adenocarcinomas and is associated with positive lymph node status" doc
Ngày tải lên :
18/06/2014, 16:20
... was
significantly (p = 0.01) lower in comparison to EAC without BE. Normal tissue is considered as one-fold (b). Statistically significant value is
indicated with an asterisk.
Grimm et al. Journal of Translational ... survival
effect [46] but may be associated with neoplastic pro-
gression in BE [47]. Therefore, our results may indicate
that MMP-1 expression is associated with multistep car-
cinogenesis according to clonal ... same as described for immunohistochemistry
Table 1 Clinicopathological characteristics of the EAC study
population (with and without histological proven BE)
Characteristics Patients
(n = 60)
MMP-1...
- 11
- 647
- 0
