... dehydro-genases (ADH) in the brain is of great interest because of their role in both ethanol and retinoic acid metabolism.Conflicting data have been reported in the literature. ByNorthern blot and enzyme ... because of their implications in the metabolism of ethanol and retinoic acid. In vitro and in vivo data indicatethat ADH1, ADH3 and ADH4 can oxidize retinol toretinal, with ADH4 having very ... expression of ADH3 in most of the analyzed areas in the brain, withhighest expression levels in hippocampus, cerebellum and particularly in human brain, in the red nucleus. Using the same methodology,...