... writing process resulted in either an unin-tentional significant reduction inthe probability of treatmentbeing timely and effective or an unintentional significantincrease inthe risk of harm when ... prescribing errors [13].Most of the errors were defined as 'minor' in outcome and, assuch, did not cause the patient harm but, in some cases, mayhave lead to an increase in monitoring ... adverse incident reports. Patient outcome was assessedby the pharmacist and clinical director, who were not blindedto the prescribing system; this could have introduced the potential for bias in the...
... entered into the 2003 NBI. The delay may be due to a lag betweeninspection and entry of data into the NBI. Therefore, data on bridges built during 2001 and 2002 maybe incomplete. The incomplete ... maintaining the NBI is to monitor the condition of bridgescarrying public highways. Therefore, for funding and reporting purposes, the FHWA considers onlystructures meeting the following criteria:ã ... for the application of this information. The Portland Cement Association DISCLAIMSany and all RESPONSIBILITY and LIABILITY for the accuracy of the application of the informationcontained in...
... 1% inthe Ciskei bought their food from the farm gate. This finding is consistent with information that has established the decline of agriculture generally inthe province. Inthe Ciskei, the ... significantly high and are close to the 2008 peak levels, with the World Bank Food Price Index increasing by 33 percent inthe last year. Investigating what people buy andthe factors influencing their ... long way in influencing the target market and marketing approach to drive the demand of organics. The second LDF 2 identified the person responsible for shopping andthe location of the consumer...
... and finance since controlling the risk-taking in banking relates directly to the protection both of depositors andthe financial system as a whole. Moreover, there is a clear conflict inside ... (1995) or Anderson and Fraser (2000) analyse the link between managerial ownership and risk-taking. Demsetz and Strahan (1997) analyse the link between size and bank risk. Risk taking inthe Spanish ... the results of the estimation andthe tests of the hypotheses. Section 6 contains the main conclusions. 2. Theoretical Background and Hypotheses 2.1. The moral hazard problem and owner-manager...
... between the cardiac muscle fibers and appears to‘diffuse’ into the myofibrils, is also evident in the Fabry mice (Fig. 7A). The VT1 binding inthe Fabrymouse lung (Fig. 7C) was increased inthe bronchiolarepithelium. ... excess staining was removed by immersing sections in distilled water for 4 min and ‘blued’ by immersing in tapwater for 4 min. Sections were then dehydrated for 2 min. in each of 70%, 95% and 100% ... 6A), but within the Fabry liverVT1 binding detected Gb3 in the stellate Kupffer cells,distributed throughout the section, andin cells lining the portal triad. The levels detected in Fabry mouseliver...
... damagedprotein and/ or a decrease inthe amount of this protein in the matrix. We have not detected any significant modifica-tion inthe amount of this protein inthe matrix. We canconclude that the decrease ... matrix.Western blotting of modified proteinsWe identified the major proteins inthe mitochondrialmatrix by performing SDS/PAGE separation and staining the gel with Coomassie blue or Western blotting. Analysisof ... oxygen consumed per minute and per mg protein. The rate of oxygen consumption in state 3 andin state 4,respiratory control ratio (RCR) of oxygen consumptions in states 3 and 4 andthe ADP/O ratio...
... can be oxidized in brain homogenates and that catalase is involved in the accumulation of acetaldehyde inthe brain [27], explainingits presence despite the absence of ADH1 andthe factthat acetaldehyde ... because of their implications inthe metabolism ofethanol and retinoic acid. In vitro andin vivo data indicatethat ADH1, ADH3 and ADH4 can oxidize retinol toretinal, with ADH4 having very high ... dehydro-genases (ADH) inthe brain is of great interest because oftheir role in both ethanol and retinoic acid metabolism.Conflicting data have been reported inthe literature. ByNorthern blot and enzyme...
... determining the inhibitory action of MIH and CHH on the target tissue, receptor binding, a secondmessenger pathway, MIH and CHH peptide and transcriptlevels inthe XO with reference to the moult ... quantitativeRT-PCR, and stored neuropeptide levels inthe sinus glandwere quantified during intermoult and premoult. The resultsshow that the most important level of moult control lieswithin the signalling ... CHHduring the moult cycle is not at the receptor level. In view of these observations, we also investigated levelsof MIH and CHH peptides inthe sinus gland and levels oftranscripts in XO neurones...
... synergy of enzymes degrading the pectin side chains was studied [34]. GALA had a positiveeffect on the activity of the other enzymes involved in the degradation of these side chains.DISCUSSIONA. ... from them, are the trueinducers of galA expression. This indicates that galA iscoexpressed with both the pectinolytic genes encoding mainchain cleaving enzymes as well as with the arabinanolyticgenes ... under the control of the xylanolytic activator protein [32,41]. The increase in expression levels of galA inthe CREA mutant,indicates that at least one of the detected putative CREAbinding sites...
... operating costs in 2005 were $4.31 per cwt inthe Northeast, $4.98 inthe Upper Midwest, and $6.49 inthe West. Milk price premiums received in 2005 were sufficient in all regions to cover the ... manure handling and storage structures, feed handling equipment, tractors, trucks, and purchased dairy herd replacements used up inthe annual production process, plus interest that the remaining ... about their future inthe business as significantly fewer had plans to exit inthe next 10 years, and significantly more planned to be in business 20 or more years. The primary difference in the...
... This indicates apredominant in uence of the catalytic domain onoligomerization.Role of the C-terminal cysteineMutation of the cysteine located at )4 from the C-ter-minus to a serine inthe ... (GNI) as a group; W8 and E9 together and separately; G13, N18, M22 and D23 together and sepa-rately; and N29 and D30 together, replacing theseresidues by the corresponding ones in a. We alsomutated ... However, inthe case ofBb, the cellular activity was decreased and secretionwas increased, suggesting that the presence of this cys-teine retains the enzyme intracellularly. In case of Aa,the...
... electrostatic interactions in SH2 domain recogni-tion: salt dependence of tyrosyl-phosphorylated peptide bindingto the tandem SH2 domain of the Syk kinase andthe singleSH2 domain of the Src kinase. ... tyrosines in TCRf and simulated trypsin digest of His-cTCRf. The ITAM tyrosineshave been named according to the ITAM they are inand their position within each ITAM (towards the NÂ or CÂ terminus). ... as 2, andthe farthest as 3. The two tyrosineswithin each ITAM are then further classified as N or C,reflecting their locations relative to the N-terminus and C-terminus (Fig. 1). Six synthetic...
... referential forms as to whether they leave behind an empty constituent inthe syntax and whether they are anaphoric inthe semantics. Empty. constituents inthe syntax are not in themselves refer- ... sented at the Annual Meeting of the Linguistic Soci- ety of America, January. Nancy Levin and Ellen Prince. 1982. Gapping and causal implicature. Presented at the Annual Meeting of the Linguistic ... features: (1) whether the form leaves behind an empty constituent inthe syntax, and (2) whether the form is anaphoric inthe semantics. In subsequent sections, we show how the distinct mecha-...
... closelyresembles the ZZ zinc-binding domain present in dystro-phin-like proteins, and CREB-binding proteins/p300homologues. The ZZ domain in dystrophin is t hought tobind calmodulin, and a missense ... motifs (see Fig. 1A).These domains include two putative metal binding regions;a zinc binding domain originally thought to belong to the B-box family of zinc binding domains and a n octicosapep-tide ... microscope (Zeiss).RESULTSNBR1 interacts with the PKC zeta interacting proteinFEZ1 andthe calcium and integrin binding protein CIB In order to identify proteins that interact with NBR1, ayeast...
... (retail chains) including: training, pricing, pecuniary and quality supervision, network control, inventory and accounting controls, advertising, local marketing and sales promotion and other network ... remains to be seen.It is the work of theoreticians of finance. Alas, they are consumed by mutual rubbishing and dogmatic thinking. The few that wander out of the ivory tower and actually bother ... contracted by the firm, including accountants, auditors, financial consultants, underwriters and brokers, the banking system and other financial venues.8. To maintain a working relationship and to...