... research of Steck et al.3 on anti- rickettsial acridines and Elslager et al.4 on anti- bacterial acridine N-oxides were the last major investigations on the antimicrobial properties of acridines.5 Ironically, ... presentation at the Medicinal Chemistry Symposium Jan 2008 National University of Singapore Nguyen, T.H.T; Lee, C.Y.; Ong, W.Y.; Doh-ura, K.; Go, M.L Investigation on antiprion activities of acridine derivatives ... Analysis of the brains of CJD patients and scrapie-infected Syrian hamsters revealed elevated levels of products of oxidation, lipoxidation, and glycoxidation.75 However, the administration of one...