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Plexin a2 and neuropilin 2 in the axonal guidance of cranial nerves in avian embryos

Plexin a2 and neuropilin 2 in the axonal guidance of cranial nerves in avian embryos

Plexin a2 and neuropilin 2 in the axonal guidance of cranial nerves in avian embryos

... patterns of plexin- A1, plexin- A2, plexin A4 and Npn-1 and Npn -2 in the developing hindbrain of chick embryos Finally, we knocked down the function of plexin- A2 and Npn -2 at the desired level of chick ... understanding how their receptors (plexin- As and neuropilins) take part in the axonal guidance of cranial and spinal motor neurons It has been demonstrated that plexin- A2 and neuropilin- 2 (Npn -2) ... fasciculation of cranial nerves in the hindbrain of chick embryos 51 Fig 21 : Representative diagram of the in- vivo function of plexin- A2 and Npn -2 in the hindbrain . 52 IV...
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Báo cáo khoa học: Cytosolic phospholipase A2-a and cyclooxygenase-2 localize to intracellular membranes of EA.hy.926 endothelial cells that are distinct from the endoplasmic reticulum and the Golgi apparatus pdf

Báo cáo khoa học: Cytosolic phospholipase A2-a and cyclooxygenase-2 localize to intracellular membranes of EA.hy.926 endothelial cells that are distinct from the endoplasmic reticulum and the Golgi apparatus pdf

... (1996) Cytosolic phospholipase A2 is in the nucleus of subconfluent endothelial cells but confined to the cytoplasm of confluent endothelial cells and redistributes to the nuclear envelope and cell ... vein endothelial cells (HUVECs) and rabbit coronary endothelial cells have reported a redistribution of cPLA2-a to the nuclear envelope [26,27] The localization of cPLA2-a in human endothelial cells ... according to cell type EA.hy.926 cells are a hybrid derived from HUVEC and A549 cells [30] In order to establish the validity of the EA.hy.926 cells as a model for studies on cPLA2-a in endothelial cells, ...
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báo cáo hóa học:

báo cáo hóa học:" The role of FGF-2 and BMP-2 in regulation of gene induction, cell proliferation and mineralization" pptx

... article as: Hughes-Fulford and Li: The role of FGF-2 and BMP-2 in regulation of gene induction, cell proliferation and mineralization Journal of Orthopaedic Surgery and Research 2011 6:8 Submit ... Figure FGF-2 and BMP-2, the yin and yang of mineralization: Contrast of effect of 24 hours of treatment with FGF-2 or BMP2 on fold increase in abundance of mineralization-related gene expression Mineralizing ... maintained the mineralizing RNA profile of igf-1, alp, and bmp-2 and significantly increased expression of other genes associated with mineralization like col1a1, fn, ilgf-1, noggin and oc Fgf-2, ...
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báo cáo hóa học:

báo cáo hóa học:" The role of FGF-2 and BMP-2 in regulation of gene induction, cell proliferation and mineralization" pdf

... article as: Hughes-Fulford and Li: The role of FGF-2 and BMP-2 in regulation of gene induction, cell proliferation and mineralization Journal of Orthopaedic Surgery and Research 2011 6:8 Submit ... Figure FGF-2 and BMP-2, the yin and yang of mineralization: Contrast of effect of 24 hours of treatment with FGF-2 or BMP2 on fold increase in abundance of mineralization-related gene expression Mineralizing ... maintained the mineralizing RNA profile of igf-1, alp, and bmp-2 and significantly increased expression of other genes associated with mineralization like col1a1, fn, ilgf-1, noggin and oc Fgf-2, ...
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Báo cáo y học:

Báo cáo y học: "Synergistic role of c-Myc and ERK1/2 in the mitogenic response to TGF-1 in cultured rat nucleus pulposus cells" ppsx

... cell cycle distribution in nucleus pulposus cells We then used flow cytometry to determine cell cycle progression by quantifying DNA Effects of inhibition of c-Myc transcriptional activity and inhibition ... high and constant level of c-Myc Also, the contribution of Ras/Raf/ERK prevented the rapid degradation of c-Myc by phosphorylation of the serine 62 residue in the N-terminal of cMyc [24] They also ... Myc function in nucleus pulposus cells using specific inhibitors The mitogenic response to TGF1 suppressed by pathway inhibitors Figure 7a,b indicate that the same levels of endogenous c-Myc...
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Báo cáo khoa học:

Báo cáo khoa học: "Expression of the metalloproteases MMP-1, MMP-2, MMP-3, MMP-9, MMP-11, TIMP-1 and TIMP-2 in angiocentric midfacial lymphomas" potx

... 11, 13 and TIMP-1 and TIMP-2 and their distribution in tissue is shown in table The expression in all the cases of MMP-1 thus neoplastic, fibroblasts and endothelial cells, may indicate a link action ... action in the degradation of the stroma The expression of MMP-2 was present basically in the neoplastic cells In the case of MMP-9 most of the cases were negative both tumoral and reactive cells The ... cellular components of the vascular wall On the other hand, 12 cases of the present series showed a more intense expression of TIMP-1 in epithelial cells, mainly the mucosal gland, whose structures...
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Báo cáo y học:

Báo cáo y học: "PKC and PKA Phosphorylation Affect the Subcellular Localization of Claudin-1 in Melanoma Cells"

... junction barrier integrity (7) Conversely, activation of atypical PKC isoforms using bryostatin instead increased the expression of claudin-1 in the tight junction complex, and increased tight ... cell motility We have previously shown that increasing the levels of CLDN-1 increases the invasion of melanoma cells (4) To determine if the increase in claudin-1 needs to be cytoplasmic and not ... nuclear localization of claudin-1 was related to the increased invasive capacity of melanoma cells, we created a claudin-1 expression vector expressing claudin-1 containing a nuclear localization...
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Báo cáo khoa học: Tumour necrosis factor-a attenuates insulin action on phosphoenolpyruvate carboxykinase gene expression and gluconeogenesis by altering the cellular localization of Foxa2 in HepG2 cells pptx

Báo cáo khoa học: Tumour necrosis factor-a attenuates insulin action on phosphoenolpyruvate carboxykinase gene expression and gluconeogenesis by altering the cellular localization of Foxa2 in HepG2 cells pptx

... a series of events beginning with the TNFa-mediated prevention of the effect of insulin on Foxa2 localization and leading to the abrogation of insulin inhibition of gluconeogenesis and glucose ... status in the presence and absence of insulin and ⁄ or TNFa Figure 2A, B shows the effects of TNFa pretreatment on insulin action on the localization of Foxa2 and Foxo1 within the cell Incubation ... effects of TNFa on insulin- mediated Foxa2 localization in HepG2 cells, and the ensuing effect on gluconeogenesis and glucose output Our results show that, in the presence of TNFa, insulin- induced inhibition...
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Báo cáo hóa học:

Báo cáo hóa học: " Vaccination with a plasmid DNA encoding HER-2/ neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial" pptx

... this article as: Norell et al.: Vaccination with a plasmid DNA encoding HER-2 /neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial ... tolerability of Her2-pDNA vaccination in combination with GM-CSF and IL-2 in a small number of advanced breast cancer patients who are on concurrent trastuzumab treatment with findings warranting ... combinations had an estimated median survival of about 58 weeks on the combination of lapatanib and capacitabine [55] The relatively long survival from the start of vaccination for patients #3 and...
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Báo cáo sinh học:

Báo cáo sinh học: " Possible active origin of replication in the double stranded extended form of the left terminus of LuIII and its implication on the replication model of the parvovirus" pptx

... at the right terminus of LuIII gesting that the left hairpin of LuIII does constitute a replication origin in the extended double stranded hairpin configuration Given the functionality of the left ... hairpin of LuIII as an origin of replication in the extended double stranded form a replication model of LuIII can be predicted resulting in equivalent amounts of plus and minus DNA viral strands ... representing the left end hairpin of LuIII in double stranded form The smaller of the two bands, of greater intensity, may represent the left hairpin with an alternate conformation A faint band of similar...
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báo cáo hóa học:

báo cáo hóa học:" Possible active origin of replication in the double stranded extended form of the left terminus of LuIII and its implication on the replication model of the parvovirus" ppt

... at the right terminus of LuIII gesting that the left hairpin of LuIII does constitute a replication origin in the extended double stranded hairpin configuration Given the functionality of the left ... hairpin of LuIII as an origin of replication in the extended double stranded form a replication model of LuIII can be predicted resulting in equivalent amounts of plus and minus DNA viral strands ... representing the left end hairpin of LuIII in double stranded form The smaller of the two bands, of greater intensity, may represent the left hairpin with an alternate conformation A faint band of similar...
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Báo cáo y học:

Báo cáo y học: "Expression of novel extracellular sulfatases Sulf-1 and Sulf-2 in normal and osteoarthritic articular cartilage" pdf

... processes Competing interests The authors declare that they have no competing interests Sulf-1 and Sulf-2 expression in murine temporomandibular joints joints Safranin O staining (a-c) and immunohistochemistry ... cartilage Sulf-1 and Sulf-2 are highly expressed in OA cartilage, especially in clusters and even in normal- appearing cartilage in OA joints The ability of Sulfs to regulate growth factor pathways (such ... Mankin score: to points) as determined by real-time PCR (Figure 1) Localization of Sulf-1 and Sulf-2 proteins in human articular cartilage Young and old normal samples as seen on safranin O staining...
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báo cáo khoa học:

báo cáo khoa học: " Comparison of hyperthermia and adrenaline to enhance the intratumoral accumulation of cisplatin in a murin model of peritoneal carcinomatosis" potx

... this article as: Facy et al.: Comparison of hyperthermia and adrenaline to enhance the intratumoral accumulation of cisplatin in a murin model of peritoneal carcinomatosis Journal of Experimental ... uptake of platinum in peritoneal nodules and in peritoneum lining muscle when adrenaline was used in combination with cisplatin, as compared to HIPEC This underlines the interest of adrenaline to increase ... randomized studies have compared heated with non-heated intraperitoneal cisplatin in ovarian carcinoma In previous papers, we reported that intraperitoneal adrenaline increased platinum uptake...
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