Báo cáo y học: ""Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence" doc
Báo cáo y học: " Derivation and preliminary validation of an administrative claims-based algorithm for the effectiveness of medications for rheumatoid arthritis"
... and preliminary validation of an administrative claims-based algorithm for the effectiveness of medications for rheumatoid arthritis Jeffrey R Curtis1,#, John W Baddley1,2, Shuo Yang1, ... corresponds to the article as it appeared upon acceptance. Copyedited and fully formatted PDF and full text (HTML) versions will be made available soon. Derivation and preliminary validation of an administrative ... and specificity, unlike PPV and NPV, should be less dependent on the prevalence in the population, and more reflective of the test itself, lessening the impact of any unique features of the...
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Báo cáo y học: " Induction and effector phase of allergic lung inflammation is independent of CCL21/CCL19 and LT-beta
... initiation and effector phase of allergic lung inflammation is independent of LTβ and CCL21. Materials and Methods Mice LTβ knockout mice (“LTβ-KO”) backcrossed to C57BL/6 were kindly provided by ... in the absence of secondary lymphoid tissue (in LTα knockout mice [40]). Thus, allergic lung inflammation can be generated independently of organized secon-dary lymphoid tissue and the associated ... 3128-35. [29] Li L, Crowley M, Nguyen A, Lo D. Ability of a nondepleting anti-CD4 antibody to inhibit Th2 responses and allergic lung inflammation is independent of coreceptor function. J Immunol...
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Tài liệu Báo cáo Y học: Human and Drosophila UDP-galactose transporters transport UDP-N-acetylgalactosamine in addition to UDP-galactose doc
... USA) and the radioactivity retained on the đlterwas measured.Staining with lectin and antibodyLectin staining and indirect immuno¯uorescence stainingwere carried out as described previously ... molecule.Keywords: UDP-galactose transporter; UDP-galactose; UDP-N-acetylgalactosamine; nucleotide sugar transporter;site-directed mutagenesis.Oligosaccharide chains of secretory and membrane-boundglycoproteins ... obtained from the đrst PCRsể FEBS 2002 UDP-Gal transporter transports UDP-GlcNAc (Eur. J. Biochem. 269) 129 Human and Drosophila UDP-galactose transporters transport UDP-N-acetylgalactosamine...
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Báo cáo Y học: Structural and biochemical characterization of calhepatin, an S100-like calcium-binding protein from the liver of lungfish (Lepidosiren paradoxa) docx
... previously identified S100 A8 and S100 A9 from piggranulocytes [9] and discovered another member of the S100family, the S100 A12 [10]. Hofmann et al. [11] proved thatS100 A12, and possibly other ... experiments with the calhepatin antibodiesfollowed by SDS/PAGE analysis, only lungfish liver and intestine showed the calhepatin band (data notshown).Fig. 3. Primary structure of calhepatin and its ... supernatant of lungfish liver (lane 1), skeletal muscle (lane 2), intestine (lane 3), lung (lane 4),brain (lane 5), adipose tissue (lane 6), heart (lane 7) and skin (lane 8)homogenates and those of...
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Báo cáo Y học: Function and cellular localization of farnesoic acid O -methyltransferase (FAMeT) in the shrimp, Metapenaeus ensis ppt
... acid O- methyltransferase in M. ensis and is the first demonstration of the biological function of this gene. The refolding of the protein during renaturation isimportant for the function of the ... J. Yagi2 and S M. Chan11Department of Zoology, The University of Hong Kong, Pokfulam Road, Hong Kong, China;2Department of Zoology,University of Toronto, Ontario, Canada;3Department of ... may also be involved in other physiological processes apart from its role in repro-duction and metamorphosis. Further, the specific cellular localization of FAMeT in the X-organ-sinus gland complexsuggests...
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Báo cáo y học: "Clinical and immunological effects of Rituximab in patients with lupus nephritis refractory to conventional therapy: a pilot study" doc
... flow cytometry before (day 0), and at days 30 and 90 of Rituximab ther-apy. Data from all samples studied are shown in (a) , and representative histograms of flow cytometry analysis are shown in ... nephritis. In an openclinical trial, 22 patients with active systemic lupus erythematosis and renal involvement (mainly class III and IVaccording to the WHO classification) that was refractory ... systemic lupus erythematosusEffect of Rituximab therapy on different laboratory and clinical parame-ters in patients with systemic lupus erythematosus. Twenty-two sys-temic lupus erythematosus...
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Báo cáo y học: "Passage and reversal effects on gene expression of bovine meniscal fibrochondrocytes" pdf
... expression profiles of meniscal fibrochondrocytesAggrecan gene expression profiles of meniscal fibrochondrocytes. The x-axis refers to the passage number, and the y- axis to the gene expression abundance ... expression profiles of meniscal fibrochondrocytesCollagen II gene expression profiles of meniscal fibrochondrocytes. The x-axis refers to the passage number, and the y- axis to the gene expression ... chondrocytes in morphology and to upregulateFigure 2Collagen I gene expression profiles of meniscal fibrochondrocytesCollagen I gene expression profiles of meniscal fibrochondrocytes. The x-axis refers...
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Báo cáo y học: "Circadian phase-shifting effects of a laboratory environment: a clinical trial with bright and dim light" ppsx
... quality, the home and first laboratory acrophases only differed, on average, by 0.03hours. Baseline aMT6s acrophase was compared acrosstreatment and age group via 3 ì 2 ANOVA. Final aMT6acrophase ... baseline and final aMT6s acrophase data.Baseline measures of circadian malsynchronization and phase dispersion were compared via 3 ì 2 treatment-by-age group ANOVAs. Two measures of circadian ... Likewise, mean home sleep diarydata was compared with the mean diary reports of the lasttwo nights in the laboratory. Analysis of polysomono-graphic data compared data averaged across the first...
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Báo cáo y học: " Efficacy and hypnotic effects of melatonin in shift-work nurses: double-blind, placebo-controlled crossover trial" ppt
... melatonin in patients with insomnia than in healthy controls, and Haimov et al [31] found lower levels of urinary 6-sulpha-toxymelatonin in elderly patients with insomnia than in healthy elderly ... about melatonin effect on different kinds of insomnia parameters (difficulty falling asleep, difficultystaying asleep, problem waking up too early, and sleepquality) causing by shift working ... delayed sleep phasesyndrome: clinical and investigative findings in 14 subjects. JNeurol Neurosurg Psychiatry 1992, 55:665-670.39. Tzischinsky O, Dagan Y, Lavie P: The effects of melatonin...
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Báo cáo y học: "Phenotypic and functional abnormalities of bone marrow-derived dendritic cells in systemic lupus erythematosus" pot
... is properly cited.Research articlePhenotypic and functional abnormalities of bone marrow-derived dendritic cells in systemic lupus erythematosusYing J Nie1, Mo Y Mok1, Godfrey CF Chan2, ... BMDCs, bone marrow-derived dendritic cells; BMCs, bone marrow cells; FLDCs, dendritic cells induced by FL; mDCs, myeloid dendritic cells; FL, FMS-like tyrosine kinase 3 ligand; GM-CSF, granulocyte ... SLE, systemic lupus erythematosus; FLDCs, dendritic cells induced by FL; mDCs, myeloid dendritic cells induced by GM-CSF + IL-4; FL, FMS-like tyrosine kinase 3 ligand; GM-CSF, granulocyte macrophage-col-ony-stimulating...
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Báo cáo y học: " Weight and metabolic effects of cpap in obstructive sleep apnea patients with obesity" pot
... changes in insulinsensitivity induced by CPAP in this setting are mainlydetermined by changes in body weight. CPAP treatmentinduced a decrease in fasting ghrelin levels, althoughbody weight increased ... unchanged. Forty percent of patients gained weight significantly. Changes in body weight directly correlated with changes in insulin and IR. Ghrelin changesinversely correlated with changes in IR but ... treatment in thispopulation. These findings also suggest that CPAP alonemay not reduce body weight, and that in the face of weight gain CPAP treatment may not reduce insulinresistance and leptin...
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Báo cáo y học: ""Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence" doc
... toxicity. Finally, we are currently searching for novel γ-glutamyl-cysteine synthetase inhibitors acting in the nanomolar range and displaying lower toxicity thanBSO in uninfected cells. The concept ... and LA conducted synthesis and development of the HDACi. LA conducted the HDACinhibitory assays. ATP and EG contributed the idea of using BSO for HIV-1 escape from latency and participated in ... HDACIs, MS-275 and buthionine sulfoximine (BSO), alone or in combinationFigure 4 Effects on HIV-1 replication and cell viability of class I-selective HDACIs, MS-275 and buthionine sulfoximine (BSO),...
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Báo cáo y học: "Pharmacokinetics and lung delivery of PDDS-aerosolized amikacin (NKTR-061) in intubated and mechanically ventilated patients with nosocomial pneumonia" ppsx
... bronchospasm.Conclusions PDDS delivery of aerosolized amikacin achievedvery high aminoglycoside concentrations in ELF fromradiography-controlled infection-involved zones, whilemaintaining safe serum amikacin concentrations. ... hospital-acquiredorganisms) with low trough serum concentrations, even in patients receiving amikacin twice daily, thereby avoiding renaltoxicity [27]. In that study, patients given 400 mg of amikacin twice daily received ... in accordance with a preliminary study, per-formed within the framework of a double-blind, placebo-con-trolled study of PDDS-delivered aerosolized amikacin in ventilated patients with Gram-negative...
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Báo cáo y học: "Incidence and prognostic impact of new-onset atrial fibrillation in patients with septic shock: a prospective observational study" docx
... shock patients with new-onset atrial fibrillation and septic shock patients with maintained sinus rhythm. AF, atrial fibrillation; SR, sinus rhythm.Figure 4 ICU length of stay of surviving patients. ... development and mainte-nance of AF. Therefore, we analyzed inflammationparameters before and after occurrence of new-onset AF.Finally, no data regarding the treatment of new-onset AF in critically ill ... 29% and was associated with a higher ICU admission rate, longer hospital stay and greater 30-day mortality [3]. In recent years increasing attention has been devoted to atrial arrhythmias after...
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Báo cáo y học: "Reversible and permanent effects of tobacco smoke exposure on airway epithelial gene expression" pptx
... properly cited. Effects of tobacco smoke on gene expression<p>Oligonucleotide microarray analysis revealed 175 genes that are differentially expressed in large airway epithelial cells of people ... number of common bronchial airway pathways. The accu-racy of a biomarker of tobacco smoke exposure using irrevers-ible genes in additional samples suggests that theirreversibility of these gene ... adaptive responseto tobacco exposure and the detoxification of tobacco smoke components. The cytochrome p450s, CYP1A1 and CYP1B1, forexample, are among the rapidly reversible genes and areinvolved...
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Từ khóa: báo cáo y họcbáo cáo y họcbáo cáo y học cổ truyềnmẫu báo cáo y học cổ truyềnbao cao y hoc colchicinphan ban luan trong bao cao y hoc co truyenbenefits such as pensions and other retirement benefits which are considered defined contributions in accordance with the recognition and measurement standardsbáo cáo khoa học y họcbáo cáo y tế học đườngmẫu báo cáo y tế học đườngbáo cáo y tế học đường cuối nămbáo cáo y tế học đường năm 2012báo cáo y tế học đường trường mầm nonbiểu mẫu báo cáo y tế trường họcbáo cáo y tế học đường trường tiểu họcBáo cáo quy trình mua hàng CT CP Công Nghệ NPVNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Nghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếThơ nôm tứ tuyệt trào phúng hồ xuân hươngTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtchuong 1 tong quan quan tri rui roNguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtĐổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namHIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀMTÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ