Báo cáo y học: "Activation of transforming growth factor-β1 and early atherosclerosis in systemic lupus erythematosus" pptx
Báo cáo khoa học: Control of transforming growth factor b signal transduction by small GTPases pot
... endocyto-sis and recycling. The cycling of Rab5 between the GTP and GDP forms may in uence the length and intensity of TGFb ⁄ activin signalingcascades by regulating TGFb–activin type I ⁄ II receptor ... phosphorylate and activate LIM-kinases 1 and 2, respectively [128–132]. Eventually, LIM-kinases1 and 2 phosphorylate actin-depolymerizing proteinssuch as cofilin, destrin and actin-depolymerizing ... disintegrin and metalloprotein-ase) facilitated signaling by inducing the accumulation of TbRII in early endosomal vesicles and counteract-ing the internalization of TbRII into a caveolin1-posi-tive...
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Báo cáo khoa học: Activation of hepatocyte growth factor activator zymogen (pro-HGFA) by human kallikrein 1-related peptidases docx
... Osada2 and Hiroaki Kataoka11 Section of Oncopathology and Regenerative Biology, Department of Pathology, Faculty of Medicine, University of Miyazaki, Japan2 Department of Urology, Faculty of Medicine, ... proteins were extracted, and the processing of pro-HGF ⁄ SF was analyzed by immunoblot analysis. Themigration capability of SUIT-2KLK5 cells was analyzedusing poly(vinyl pyrrolidone)-free polycarbonate ... Thermolysin also activated pro-HGFA, and the addition of phosphoramidoncompletely inhibited the activity of thermoly-sin. Processing of pro-HGFA was deter-mined by SDS ⁄ PAGE under reducingconditions...
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Báo cáo Y học: Interaction of bovine coagulation factor X and its glutamic-acid-containing fragments with phospholipid membranes A surface plasmon resonance study pdf
... Ca2+ligatingamino acids in the N-terminal part of the first EGF-likedomain of factor X in uences the amidolytic activity of theintact protein [36]. However, direct interactions between theGla and serine ... for binding intact factor X and Gla–EGFN(data not shown).Kinetics of membrane bindingThe kinetics of binding to PL membranes of the zymogenfactor X, activated factor X (factor Xa) and the ... Mode of action of vitaminK and calcium binding properties of bovine prothrombin. Bio-chemistry 11, 4961–4964.24. Stenflo, J. & Ganot, P. (1973) Binding of Ca2+to normal and dicoumarol-induced...
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Báo cáo Y học: Activation of transcription of the human presenilin 1 gene by 12-O-tetradecanoylphorbol 13-acetate pdf
... Tremblay, R., Chakravarthy, B., Mealing, G.,Morley, P., Small, D. & Song, D. (1997) Evidence that the early loss of membrane protein kinase C is a necessary step in theexcitatory amino acid-induced ... detect changes in the bindingactivity of the proteins recognizing specifically the )10region of the PS1 promoter in nuclear extracts of SK-N-SHcells treated with TPA (Fig. 6). In dimethylsulfoxide-treatedFig. ... an increase in the rate of initiation of transcription of PS1.PS1 protein level increases with TPATo confirm and extend the previous observations we haveexamined the level of PS1 protein in...
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Báo cáo Y học: Activation of transcription through the ligand-binding pocket of the orphan nuclear receptor ultraspiracle docx
... ability of the wild-type dUSP and dominant negative, ligand-binding pocket mutant dUSP tobind methyl epoxyfarnesoate. In a ligand-binding assay thatdetects methyl epoxyfarnesoate binding through ... movement of the ligand-binding domain a-helix 12. Ligand-bindingpocket point mutants of USP that do not bind methylepoxyfarnesoate act as dominant negative suppressors of methyl epoxyfarnesoate-activation ... carbon backbone and blue terminal carboxylate oxygens) lainmanually in the dUSP ligand-binding pocket with the carboxy and distal (epoxy) ends, respectively, situated in similar regions of the pocket...
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Báo cáo Y học: Activation of a covalent outer membrane phospholipase A dimer pptx
... determined in kinetic assays. Catalytic calcium binding was determined in both wild-type OMPLA and the covalentOMPLA dimer in the kinetic assay, in which the mole fraction of substrate in the ... This stronglysuggests that the type of substrate in uences dimerizationthereby indirectly in uencing binding of the catalyticcalcium for wild-type OMPLA.Subsequently, it was investigated ... covalentOMPLA dimer was independent of type and concentration of detergent in micellar systems. In such systems, the cova-lent OMPLA dimer invariantly displayed high calciumaffinity. In contrast, high...
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Báo cáo y học: " Implementation of a new emergency medical communication centre organization in Finland an evaluation, with performance indicators"
... prolongation in theanswering and processing times of emergency calls in Helsinki, the capital of Finland [5].EMCC organization and EMD in Finland - before and nowThere used to be 45 municipality-based ... handbook for drawing up an alarmprocedure. Finland Helsinki; 2005, 56.7. Kuisma K, Boyd J, Väyrynen T, Repo J, Nousila-Wiik M, Holmström P:Emergency call processing and survival from out of ... dispatching centres into one entity:effects on performance. Acta Anaesthesiol Scand 2010, 54(6):689-695.6. Handbooks of the Ministry of Social Affairs and Health Ambulance and emergency care...
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Báo cáo khoa học: Activation of activating transcription factor 2 by p38 MAP kinase during apoptosis induced by human amylin in cultured pancreatic b-cells ppt
... treatment, as shown by increased intensities of both shifted bands in hA-treated cells. In addition,the increased CRE binding activity was suppressedby JNK inhibitor I and SB 203580, implying thathA-evoked ... CRE binding is mediated by both the JNK and the p38 kinase pathways.Additionally, supershift assays (antibody pre-incuba-tions) were performed to determine which types of CRE-binding protein ... Dragunow2 and Garth J. S. Cooper11 The School of Biological Sciences, Faculty of Science, University of Auckland, New Zealand2 Department of Pharmacology and Clinical Pharmacology, Faculty of Medical...
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Báo cáo Y học: Complexation of ytterbium to human transferrin and its uptake by K562 cells pot
... Lu3+,Sm3+ and Eu3+,respect-ively [34]. Both UV and ICP-AES data suggested that twoYb3+bind to apo-Tf in the specific iron binding site and twotyrosines are involved in binding of Yb3+ in both ... with Band Pass (BP) filter and LongPass (LP) 590 nm filter.RESULTSBinding of Yb3+to apo-hTfThe thermodynamics of binding of Yb3+to apoTf.Binding of Yb3+to apo-Tf was investigated by addition of ... study of uptake of Yb3+by human Tf (hTf) by UV-vis and NMR spectroscopy, and inductively coupled plasma atomic emission spectro-metry (ICP-AES). The binding of Yb-bound Tf to humanerythroleukemia...
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Báo cáo Y học: Overexpression of a recombinant wild-type and His-tagged Bacillus subtilis glycine oxidase in Escherichia coli pptx
... Analogously, GO and MSOX show a fairlysimilar activity o n s arcosine and N-ethylglycine. In contrast,an appreciable activity on glycine, glycine-ester a ndD-pipecolic acid was only observed using ... Comparison of thethree-dimensional protein and nucleotide struc ture of the FAD-binding domain of p-hydroxybenzo ate hy droxy lase with the FAD-as well as NADPH-binding domains of glutathione ... confirms that Y2 46 ishighly c onserved and is located a t a position resembling that of Y2 23 in DAAO and Y2 54 in MSOX. Even the arginineresidue (R285 in yeast D AAO) which e lectrostaticallyinteracts...
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Từ khóa: transforming growth factorβ1 induced epithelialmesenchymal transition in hepatic fibrosisbáo cáo y họcbáo cáo y họcbáo cáo y học cổ truyềnmẫu báo cáo y học cổ truyềnbao cao y hoc colchicinphan ban luan trong bao cao y hoc co truyeninduction of cardiac fibrosis by transforming growth factorβ1transforming growth factor β1transforming growth factorβ1 from human plateletstransforming growth factorβ1 humantransforming growth factorβ1 genemicrornas transforming growth factor beta1 and tissue fibrosistransforming growth factor b and cns scarringnghia pham thien ngoc nguyen quoc tuan 2011 research the concentrations of placenta growth factor plgf and soluble fms like tyrosin kinase 1 sflt 1 in the serum of normal pregnant women medical practice no 12 2011 pp 16 19Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Phát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngTìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinChuong 2 nhận dạng rui roTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Tăng trưởng tín dụng hộ sản xuất nông nghiệp tại Ngân hàng Nông nghiệp và Phát triển nông thôn Việt Nam chi nhánh tỉnh Bắc Giang (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)MÔN TRUYỀN THÔNG MARKETING TÍCH HỢPQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ