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Báo cáo sinh học: "Promoter architecture and the evolvability of gene expression" pdf

Báo cáo sinh học:

Báo cáo sinh học: "Promoter architecture and the evolvability of gene expression" pdf

... amplifying gene expression. Notably, the binding of the PIC to the TATA box and the binding of transcription factors to other sites could be cooperative [44]. This would make the effect of the TATA ... underlying these differences, and how they may contribute to the evolvability of gene expression. Yeast is an excellent model for studying the evolution of gene expression because of its simplicity ... activity of the chromatin regulator, could affect transcription of the downstream target gene. Unstable tandem repeatsSo far we have discussed the role of promoter architecture in the sensitivity...
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báo cáo sinh học:

báo cáo sinh học:" Human resources and the quality of emergency obstetric care in developing countries: a systematic review of the literature" potx

... resources; and four, organizationalresources. The structural aspects of EmOC and the inter-personal constituents of the EmOC process were easilyidentified. The clinical aspects of EmOC, where the ... AND "quality health care ORquality care" AND "developing countries".Based on the advice of one of the authors (PF), an expertin the field of maternal health and EmOC, the ... results.Once the relevant data had been extracted and the studiessummarized, the remainder of the analysis was carried outusing the data extraction form and the analytical frame-work presented in the...
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Báo cáo sinh học:

Báo cáo sinh học: " Evolutionary genomics and the reach of selection" pps

... specify ESEs. The issue of gene location gets to the heart of the relationship between genome organization and the control of gene expression. The simplest model supposes that a gene with its ... gene can potentially influence, by accident, the expression of neighboring genes. Indeed, the transcription rate of atransgene corresponds to that of the genes adjacent to the position ... reflected in the use of the term ‘junk DNA’ todescribe intergene spacer DNA.These two schools of thought then could not be moreantithetical. And this is where genome evolution comes in. The big...
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Báo cáo sinh học:

Báo cáo sinh học: " Mayr, mathematics and the study of evolution" pot

... population genetic theory will play anincreasing role. The rise of molecular methods has led to an increase in the importance of mathematics in population genetics and evolution. The abundance of data ... it mathematically. One final exampleis the inheritance of the ABO blood groups, which was indoubt from the time of their discovery at the turn of the twentieth century until Bernstein’s mathematical ... [10]support it and favor the view that speciation genescorrespond to normal genes, selected for their effects within the species. Furthermore, there is evidence that these genesevolve rapidly....
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Báo cáo khoa học:

Báo cáo khoa học: "Mechanical Translation and the Problem of Multiple Meaning" pdf

... uncorrelativity of the random force is the shortness of its time of the correlation as compared with the time of the relaxation of the velocity for the large Brownian particles (large frequency of the ... expressed by the formula of the Boussinet, then the assumption about the random force will lead, in particular, to the results of the work. The physical reason of the assumption about the uncorrelativity ... legitimate and the theory correctly describes the process, taking place in the interval of the time within the time of the relaxation (and more), then it is, nevertheless, not applicable for the...
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Báo cáo sinh học:

Báo cáo sinh học: " Nucleocapsid formation and RNA synthesis of Marburg virus is dependent on two coiled coil motifs in the nucleoprotein" pot

... arenecessary and sufficient to mediate protein-protein inter-action.We then investigated whether the integrity of the coiledcoil region of NP is important for the binding of NP to the polymerase cofactor ... for the homooligomerization of NP,formation of NP-induced intracellular inclusions, interac-tion of NP with VP35 and for the function of NP in RNAsynthesis.Materials and methodsCells and ... consisting of NP, VP35, and L with VP35 connecting L and NP [6]. Three of the four nucleocapsid proteins, NP, VP35, and L, are essentialfor transcription and replication of the viral RNA [12]. The fourth...
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Báo cáo sinh học:

Báo cáo sinh học: " No relationship between the distribution of mast cells and the survival of stage IIIB colon cancer patients" pdf

... en-ter of Sun Yat-Sen University. All the patients under-went radical surgery, and none of them had undergoneeither chemotherapy or radiotherapy before the collec-tion of the samples. The histopathologic ... Committee of our institution. Patients were informed of the investiga-tional nature of the study and provided their writteninformed consent.Follow-up of patientsFollow-up was provided to all of the ... 9:88http://www.translational-medicine.com/content/9/1/88Page 6 of 6These results also refute the randomized distributionmodel of mast cells in cancer tissues suggested byRibatti [20]. The reason that this kind of non-rando-mized distribution of mast...
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Báo cáo sinh học:

Báo cáo sinh học: "Phylogenetic evidence for the distinction of Saaremaa and Dobrava hantaviruses" pot

... participated in the analysis of the results and drafted the manuscript. AV participated in the analysis of the results and helped to draft the manu-script. AP designed the study, participated in the analysis of ... set [22,23]. The test for molecular clock and esti-mation of the time of split of these two viruses was donewith TreePuzzle [21].Competing interests The author(s) declare that they have no ... single-stranded RNAgenome of negative polarity [1]. The large (L) segmentencodes the viral RNA polymerase, the medium (M) seg-ment the two surface glycoproteins, and the small (S) seg-ment the...
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Báo cáo sinh học:

Báo cáo sinh học: "Wnt signaling and the developmental fate of lung cells" ppsx

... in them. of local injury and inflammation thereis local up-regulation of Wnt signaling and the activity of ␤-catenin, and thatthis is then switching some of the cellsto become progenitors of ... receptorat the surface of a cell, it blocks degradation of the co-factor ␤-catenin and frees it to interact with the transcription factors of the TCF/LEF family, thereby triggering the transcription of ... onepart of the body that normally belongin another. Neither group could get ahandle on how cells escape the usual‘rules’ that tell them which types of tissue to form in which part of the body....
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Báo cáo y học:

Báo cáo y học: "Human toxoplasmosis and the role of veterinary clinicians"

... toxoplasmosis is one of the most com-mon parasitic zoonoses worldwide. As for other zoonoses, veterinarians play an important role in the education of the human population regarding the risk of infection. ... perform the task, they should wear disposable gloves and wash their hands thoroughly with soap and wa-ter afterwards. Direct contact with cats is unlikely to result in transmission of toxoplasmosis ... pregnancy and that if they follow a few very simple “rules”, liv-ing with their pets need not represent any risk for infection with Toxoplasma gondii. Cats are the definitive host of T. gondii; they...
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