assumptions underlying the translation of gene expression into metabolic changes
Báo cáo y học: "The Proteomic Code: a molecular recognition code for proteins" docx
... reverse (5'→3'/5'→3') orientation The Origin of Proteomic Code as part of the Genetic Code The theory of Ikehara [reviewed in [96,97]] about the origins of gene, genetic code, protein and life is ... under the control of the strong lacUV5 promoter A protein of interest is fused to the bacterial phage λcI protein by inserting its gene into the multiple cloning site at the 3' end of the λcI gene ... target sequences the progression of the residues Synthesis pattern for construction of depending on the and Synthesis pattern for construction of target sequences and the progression of the permutations...
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Báo cáo khoa học: A novel plant protein disulfide isomerase family homologous to animal P5 – molecular cloning and characterization as a functional protein for folding of soybean seed-storage proteins docx
... (supplementary Fig S4) Nucleotide sequence of the ORF of the GmPDIM gene was identical to that of the cDNA Comparison of the soybean genomic sequence of GmPDIM with those of A thaliana (AGI number At1g04980 ... grew to 100 mg Expression of GmPDIM increased in the late stage of seed development (Fig 3B) These results suggest that upregulation of the expression of GmPDIM occurs at a time when the requirement ... Large amounts of seed-storage proteins are synthesized and are translocated to the ER during the maturation stage of embryogenesis Previously, we demonstrated that the synthesis of glycinin was...
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Báo cáo hóa học: "Reference values and physiological characterization of a specific isolated pig kidney perfusion model" doc
... examine the creatinine clearance used as approximation of the glomerular filtration rate (GFR) The creatinine clearance represents the mathematical product of the U/Pcrea quotient and the urine-flow ... for the collection time at 60 after start of the perfusion Generally the blood parameters were kept in approximation to the physiological ranges by periodically controlling the composition of the ... qualify the outcome of the isolated kidney In this respect, considering the nephron's handling of substrates, the tubular reabsorption of sodium is a further prominent mechanism and the fractional...
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Báo cáo hóa học: " Design and Characterization of a 5.2 GHz/2.4 GHz ΣΔ Fractional-N Frequency Synthesizer for Low-Phase Noise Performance" potx
... Each of the three loops is identical The input of the second loop is taken from the quantized error Eq1 of the first loop, while the input of the third loop is taken from the quantized error Eq2 of ... between these two curves at an offset frequency of 200 kHz Therefore the best possible out -of- band phase noise is the raw phase noise of the VCO and the inband phase noise will be dominated by the ... phase of the output and ϕn (t) is the time-variant random phase fluctuation of the output signal due to any noise sources in the PLL Phase noise is often quoted in units of dBc/Hz or rad2 /Hz The...
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Báo cáo khoa học: A strategy for the generation of specific human antibodies by directed evolution and phage display An example of a single-chain antibody fragment that neutralizes a major component of scorpion venom docx
... C noxius venom To the best of our knowledge, this is the first report of the generation of a human recombinant antibody fragment capable of neutralizing the toxic effects of the whole venom from ... One of these changes occurred at framework of the heavy chain (Asp74Asn) and of the light chain Two of the changes (Thr152Ile and Ser197Gly) occurred at frameworks and 3, respectively, and the ... of mouse weight) [13] Clone 3F was matured by three cycles of directed evolution The use of a set of stringent conditions in the third cycle allowed the selection of several improved clones The...
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Báo cáo hóa học: " Nucleotide mismatches between the VP7 gene and the primer are associated with genotyping failure of a specific lineage from G1 rotavirus strains" potx
... was reported that the accumulation of point mutations in VP4 and VP7 genes was the main cause of the failure of the G or P-typing of rotavirus strains [7,8,12,16-21] At least, there are four multiplex ... out of 121 G1 strains from lineage I showed the four specific mismatches at the 5' end of the 9T1-1 primer This was associated with the failure of genotyping of G1 strains from Bangladesh Two of ... suggested the use of modified or degenerated primers to avoid the mismatches between the primer and the VP7 gene [17,20] Lineage I In a recent paper published by Rahman et al [19], it was reported the...
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Báo cáo y học: "Validation of a specific measure to assess healthrelated quality of life in patients with schizophrenia and bipolar disorder: the ‘Tolerability and quality of life’ (TOOL) questionnaire" doc
... in these multidimensional scales we used the unweighted scores In both cases, the higher the scores, the better the HRQoL, and vice versa (2) The Spanish version of the TOOL questionnaire The ... responded to the inverse scoring of the measures In addition, the associations between the TOOL items and the generic measures of HRQoL (Table 4) were negative, Montejo et al Annals of General Psychiatry ... from the report from the Chair of the Outcomes Reference Group Leeds, UK: National Institute of Mental Health in England; 2005 Thornicroft G, Tansella M: Growing recognition of the importance of...
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Báo cáo y học: "Association of a specific haplotype across the genes MMP1 and MMP3 with radiographic joint destruction in rheumatoid arthritis" ppt
... significant at the 5% level In factorial regression, there also was a correlation of the SE with the Ratingen score (P = 0.044) The presence or absence of the SE explained 29% of the variance of the Ratingen ... of the inheritable factors of RA has largely focused on components of the immune system, such as the SE and the cytokine network [1,2,30] In the cohort investigated here, the association of the ... attributed to the proximity of the MMP1 and MMP3 genes Both genes have been mapped to the long arm of chromosome 11 in the region 11q22.3 [16], with a distance between them of 37.64 kilobases The biological...
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Báo cáo y học: "The identification and characterization of a novel protein, c19orf10, in the synovium" docx
... sequence of c19orf10 (a) The chromosomal localization of the region containing the c19orf10 c19orf10 gene is indicated on the ideogram The area containing the c19orf10 gene is expanded and the base-pair ... area of the putative signal peptide were poorly conserved although the majority of the residues were non-polar The remainder of the protein showed a high degree of conservation between the human ... product of 3T3 fibroblasts as they differentiate into adipocytes Collectively, these observations suggest that c19orf10 may not be unique to the synovial compartment; however, the results of the...
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báo cáo khoa học: "Design and characterization of protein-quercetin bioactive nanoparticles" doc
... measurements of the BSA system The concentration of BSA was 1.5 × 10-5 mol/L (A) ACF of BSA vs the concentration of DMSO; (A’) Size distribution histogram of BSA vs the concentration of DMSO; (B) ACF of ... measurements of the Lys system The concentration of Lys was 1.5 × 10-5 mol/L (A) ACF of Lys vs the concentration of DMSO; (A’) Size distribution histogram of Lys vs the concentration of DMSO; (B) ACF of ... measurements of the Mb system The concentration of Mb was 1.5 × 10-5 mol/L (A) ACF of Mb vs the concentration of DMSO; (A’) Size distribution histogram of Mb vs the concentration of DMSO; (B) ACF of Mb...
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Design and characterization of functional novel oligopeptides
... Three of the peptides synthesized consist of alternating hydrophobic and hydrophilic residues Out of these three peptides, two of them consist of a cell adhesion motif ‘RGD’ in the middle of the ... self-assembly offers the possibility of incorporating biofunctionality into the material 1.2 Self-Assembly of Peptides Molecular self-assembly is the spontaneous organization of molecules under thermodynamic ... complete automation of the entire synthesis is possible At the same time, some of the potential disadvantages of the stepwise SPPS involve incomplete reactions and the gradual buildup of insoluble by-products...
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Design and characterization of interposers for high speed fine pitch wafer level packaged device testing
... contributing to the signal degradation is the design of the printed circuit board (PCB) part of the interposer 75 % of the loss of the overall test system is attributed to this board viii List of Figures ... 4.7: Cross sectional view of the interposer showing the thickness of the layers and the composition of the materials used 63 Figure 4.8: Top view showing the layout of the proposed elastomer interposer ... governed by the number of probes in the array and their proximity to each other Varying the width of the blade shank increases or decreases the surface area where the blade is attached to the probe...
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Tài liệu Báo cáo khoa học: Characterization of a chemosensory protein (ASP3c) from honeybee (Apis mellifera L.) as a brood pheromone carrier pdf
... and transferred into the Pichia pastoris yeast host by the electroporation method as described in the manual (version 3.0) of the Pichia expression Kit (Invitrogen) The selection of multicopy integrants ... equivalent (Qeq), the average amount of pheromone found in the gland of mated queen [50] The synthetic pheromone blend was dissolved in ethanol to a final concentration of 10 mgÆmL)1 Other competitor ... frame encodes a 130-amino acid polypeptide The comparison of the amino acid sequence deduced from the cDNA sequence with that of the N-terminal sequence of the natural ASP3c protein [20] showed that...
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Báo cáo khoa học: Characterization of the role of a trimeric protein phosphatase complex in recovery from cisplatin-induced versus noncrosslinking DNA damage potx
... Substitution of the H2AX Ser129 by Ala restored the ability of the pph3D strain to turn off checkpoint signalling in a timely manner and re-enter the cell cycle after DNA repair of the double-strand ... amounts of cH2AX generated in the presence of increasing doses of MMS (Fig 3C) and even with the low levels of cH2AX that were sometimes present in yeast cell lysates in the absence of DNA-damaging ... [9] One of the earliest events in the cellular response to many DNA-damaging agents is the phosphorylation of histone 2AX (H2AX) at Ser129 in its C-terminal tail and the accumulation of the phosphorylated...
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Báo cáo khoa học: Proteome analysis of a rat liver nuclear insoluble protein fraction and localization of a novel protein, ISP36, to compartments in the interchromatin space pptx
... from the interchromatin region and found in the periphery of condensed chromosomes (Fig 9, panels and 7) Some of the ISP36 did not diffuse into the cytoplasm and remained near the chromosomes These ... underneath the inner nuclear membrane and function to maintain the nuclear architecture [3] The majority of vimentin may be bound to the nuclear lamina from the outside the nucleus [18] The presence of ... actin in the nucleus has been demonstrated by immunogold staining with partial digestion of the surface lamina of the nuclear matrix to allow penetration of the gold particles into the nuclear...
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Knowledge transfer in Tehran University of Medical Sciences: an academic example of a developing country pdf
... Priorities of the professoriate New York, The Carnegie Foundation for the Advancement of Teaching; 1990 Glassick CE, Huber MT, Maeroff GI: Scholarship assessed: Evaluation of the professoriate ... of the total score The maximum score attainable in the active strategies was six and the mean score of the researchers' performance in these strategies was 0.54 (SD = 1.02), which consisted of ... 9% of the total score Table and show the results of a linear regression analysis with the 'Enter' method As shown in tables and 4, the dependent variables in these regressions are the scores of...
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báo cáo khoa học: " Knowledge transfer in Tehran University of Medical Sciences: an academic example of a developing country" pot
... Priorities of the professoriate New York, The Carnegie Foundation for the Advancement of Teaching; 1990 Glassick CE, Huber MT, Maeroff GI: Scholarship assessed: Evaluation of the professoriate ... of the total score The maximum score attainable in the active strategies was six and the mean score of the researchers' performance in these strategies was 0.54 (SD = 1.02), which consisted of ... 9% of the total score Table and show the results of a linear regression analysis with the 'Enter' method As shown in tables and 4, the dependent variables in these regressions are the scores of...
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Magnetic resonance spectroscopy correlation with histological analysis in gliomas and structure determination of a hypothetical protein
... shifts of metabolites With the chemical shift database of metabolites and the correlations between protons provided by the COSY spectrum, almost all of the metabolites shown in the HSQC spectrum of ... absence of NAA and the presence of Lactate or lipids An excellent correlation between regional neuron loss and regional NAA decrease was found Furthermore, the disappearance of the metabolites of ... detect and diagnose type of brain diseases at the beginning The more efficient and accurate the diagnosis is made, the higher the possibility for the patient to be cured Therefore it is significant...
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Báo cáo khóa học: Functional properties of the protein disulfide oxidoreductase from the archaeon Pyrococcus furiosus A member of a novel protein family related to protein disulfide-isomerase doc
... the presence of the nucleotide These experiments indicate that the binding and/or hydrolysis of ATP not have any effect on the conformation of PfPDO, possibly because of the localization of the ... participation of both N-terminal and C-terminal active sites Refolding of the scrambled RNase in the presence of PDI was used as a positive control, and the absence of the recovery of the RNase activity ... using PDI However, the temperature of the assay, which is limited by the stability of the protein substrate RNase, is very far from the optimal growth temperature of the hyperthermopilic micro-organism...
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Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25