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... pumps isassumed to correspond to the outward-facing confor-mation. The energy produced by the hydrolysis ofATP is harnessed for the resetting of the transporterto the initial high-affinity, inward-facing ... supported by the restoration of high-affinity binding in the ADP-bound conformation. That this step of the catalyticcycle is associated with the greatest free energy changealso makes it ideal for the ... although the binding data cannotunequivocally inform on the orientation of the sites,only their affinity for interaction with drugs. The data presented here suggest that the ABC-G2R482Gisoform...

... 0‐12**≥50%ofaudiencemustbechildren;**≥35%ofaudiencemustbechildren;***≥30%ofaudiencemustbechildren.****≥25%ofaudiencemustbechildren.~ unless anadultispresent.~~ unless adultspredominate.+≥35% for someshowsand≥50% for others.++11 for printmedia, otherwise 12.Whichproductscanbepromoted?In the USAalargenumberofcompany‐promotedmodelshavebeenproposed for defining the nutritionalcriteria for foodstobemarketedtochildren21andasimilarproblemhasariseninEurope. The nexttablegivesexamplesofnutrientmethods for definingfoodsassuitable for marketingtochildren,asproposed by someof the companiesin the EUpledge:Table2Company‐setcriteria for foodstheycanmarkettochildrenCompany ... 221SummaryDuring the lastdecadeconsumergroups,parentsandteachers’bodies,andpublichealthadvocacyorganisationshavecalled for greatercontrolon the marketingoffoodsandbeveragestochildren.Anumberofauthoritativereportshavehighlighted the needtorestrictsuchmarketingtoensurethatchildren are notundulyinfluencedtoconsumefoodshighinfats,sugarandsalt.A2009reviewofregulations (the PolMarkstudy1)suggestedthatsuccessfulregulationrequiredgovernmentleadershipwithspecifiedtimelinesandclear,measurableobjectives.In2010 the WorldHealthAssemblypassedaResolutionwhichurgedmemberstatestointroducecontrolson the marketingoffoodsandbeveragestochildren,andissuedasetofRecommendationsidentifying the approachesthatcouldbetaken2.Theseincreasingcalls for actionhaveledtoaseriesofpolicyresponses,includinggovernment‐ledvoluntaryagreementswithindustryandstatutoryregulation.Ofparticularimportanceis the responseofleadingfoodandbeveragecompanies,whohaveproposed the proposedaseriesofcompany‐ledpledgestoreducetheirmarketingactivitiesdirectedatchildren.Thesepledgescovertypesofmarketingpracticewhichmaylieoutside the traditionalindustry‐widecodesofconductandnationalregulationsonadvertising.However,comparisonofdifferentcompanypledgesandstatementsshowsadegreeofinconsistency,asshowninthisreport,whichmakesevaluationof the impactof the pledgeshardtoassess.Furthermorethereappeartobelapsesin the adherencetothesepledgeswithinEurope,andevidencethatthey are notappliedinotherregions(givingriseto‘off‐shore’marketingtoEuropeanchildrenvia the internet)socallingintoquestion the companies’strengthofcommitment.Inordertoassistgovernmentsandguideindustry, the StanMarkprojectundertookaseriesofpolicyandresearchmeetingsinvolvingexpertsandofficialsfromcountriesinEuropeandNorthAmerica,fundedunder the PilotProjectsprogrammeof the EuropeanUnion’sExternalAffairsService3.Fromthesemeetingsaseriesofproposalsweregeneratedand are presentedhere for use by WHOmemberstategovernments. For cross‐bordermarketingitisintendedthat the foodandadvertisingindustrieswillrecognise the advantagesofacommon,universalsetofstandardsapplicabletoallcompaniesandwhichcanprotectchildrenacross the globe. The standardsproposed are basedon the WHOrecommendations,whichidentifyboth‘exposure’and‘power’asindependentfactorsdetermining the effectivenessofmarketingmessages. The StanMarkprojectproposes the following:• ... acids, free sugars, or salt, to children. 4. Governments should set clear definitions for the key components of the policy, thereby allowing for a standard implementation process. The setting...

... FEBS(e) The reaction mixture is accessible. This allows the synthesis of proteins in the presence of other pro-teins provided in excess at the start of or during the reaction, e.g., for the purpose ... produced in highyields in vivo are also suitable for efficient production by cell -free synthesis. In order to compensate for the increased effort and expense required for the produc-tion and selective ... protein samples for analysis by NMR spectroscopy.(a) The target protein is the only protein synthesizedand labelled during the reaction. Consequently the iso-tope-labelled amino acids are used very...

... XCHAPTER X The Fight for a Free Sea: A Chronicle of by Ralph D. Paine The Project Gutenberg EBook of The Fight for a Free Sea: A Chronicle of the War of 1812, by Ralph D. Paine This eBook is for the ... of them straggled in the rear, their crewstugging at the long sweeps or oars. Two of the faster of these, the Scorpion and the Ariel, were slipping alongin the van where they supported the ... Stillthey died in their tracks, until the survivors were actually pushed over a cliff and down to the bank of the river.There they surrendered, for there were no boats to carry them across. The...

... their composition is known.• The B adapter contains a 5’ biotin tag used for mobilization.• The beads are magnetized and attract the biotin in the B adaptors.Filtering the Mess•There are ... emitted by luciferase is proportional to the number of nucleotides incorporated.•Therefore, if the intensity of a single read is 3 times the intensity of a previous read, there are 3 times the ... lengths are around 200-300 bases.•400,000 reads of parallel sequencing•100mb of output per run•Run time 7.5 hours *Unless otherwise stated, read and output data are provided on the 454...

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... Write a report for a university lecturer describing the information in the graphs below.You should write at least 150 words. You should spend...

... report for a university lecturer describing the information in the two graphs below.You should write at least 150 words. You should spend about 20 minutes on this task.model answer: The pie ... should spend about 20 minutes on this task.model answer: The pie charts compare the highest level of education achieved by women in Someland across two years, 1945 and 1995. It can be clearly seen ... received a much higher level of education in Someland in 1995 than they did in 1945. In 1945 only 30% of women completed their secondary education and 1% went on to a first degree. No women...

... of them are the officers, who pay much attention to the products. There is a 2Trương Thuỳ Chi- CQ503891- Business English 50Asurvey for the Viet A Company’s customers and a survey for the ... although they can aware the brand, it is only at the Brand recognition in the Brand Awareness Hierarchy.In short, through the three charts, the Viet A brand equity can be evaluated as the second ... promotionAs the chart show, 80 percent of the customer will be willing to use the Viet A products again if the next purchase, they can get the special promotion. The other thinks that they will...