Báo cáo khoa học: "Speech emotion recognition with TGI" pot

Tài liệu Báo cáo khoa học: Basis of recognition between the NarJ chaperone and the N-terminus of the NarG subunit from Escherichia coli nitrate reductase pdf

... biphasic, with the best fit obtained with a two binding sitemodel, comprising a first site with binding stoichiome-try (n) of 0.3 ± 0.2 and a binding constant (Kd)of3.4 ± 4 · 10)9m and a second with ... only befitted with the 1 : 1 Langmuir model of simple binding,confirming the existence of a single state of NarJ at thispH. These results are in full agreement with thoseobtained with ITC (Table ... anextended b-hairpin in close contact with both NarH andNarI subunits [4]. Here we addressed the question ofthe structure adopted by the N-terminus of NarG dur-ing the recognition process. At first,...

Tài liệu Báo cáo khoa học: An allosteric DNAzyme with dual RNA-cleaving and DNA-cleaving activities doc

... allostericDNAzyme with dual RNA-cleaving and DNA-cleaving activities is verychallenging. We used an in vitro-selected pistol-like (PL) DNAzyme as aDNA scaffold for designing a DNAzyme with dual catalytic ... As compared with PL DNAzyme, DRc DNA-zyme function seemed to have decreased sensitivity tothe reaction temperature. DRc DNAzyme exhibited abroad functional range for temperature, with optimumactivity ... L-ascorbate inthe reaction. Lanes M I and M II were loaded with 5¢-32P-labeled synthetic DNAs of different lengths as indicated, each with a sequence thatcorresponded to the respective 5¢-terminus...

Tài liệu Báo cáo khoa học: DNA modiﬁcation with cisplatin affects sequence-speciﬁc DNA binding of p53 and p73 proteins in a target site-dependent manner pptx

... cisplatin DNA treatmentcorrelated with the occurrence of sequence motifs forming stable bifunc-tional adducts with the drug (namely, GG and AG doublets) within thetarget sites. Binding of ... protein with cer-tain response elements can be controlled by changes inDNA topology inducing formation of non-B DNAstructures within the binding sites [11,12]. Interactionsof p53 with DNA ... was observed with the anticancer tri-nuclear platinum complex BBR3464 but not with theclinically ineffective transplatin. Quite recently, it hasbeen shown that DNA modiﬁcation with a transplatinanalog,...

Tài liệu Báo cáo khóa học: Point mutations associated with insecticide resistance in the Drosophila cytochrome P450 Cyp6a2 enable DDT metabolism doc

... theRDDTRstrain were measured with all recombinant pro-teins, namely testosterone hydroxylation and DDT meta-bolism. Testosterone was hydroxylated at the 2b position with little quantitative variation ... 271, 1250–1257 (2004) Ó FEBS 2004 doi:10.1111/j.1432-1033.2004.04025.xrelation with xenobiotic metabolism or with metabolism ofendogenous compounds [24,25]. Models for CYP51 werealso built ... mutagenesis studies focused in the vicinity or insidethe substrate recognition sites (SRS [31]). These areaswere proposed to interact with the substrates of cyto-chrome P450 and thus to be responsible...

Tài liệu Báo cáo khoa học: The RNA recognition motif, a plastic RNA-binding platform to regulate post-transcriptional gene expression ppt

... in complex with RNA (the N-terminal domain of U1A in complex with U1snRNA stem-loop II [26]) that founded our under-standing of RRM–RNA recognition, 10 structuresof RRMs in complex with RNA or ... nucleolin in com-plex with RNA [28] (pdb:1fje), (C) sex-lethalin complex with RNA [31] (pdb:1b7f),(D) PABP in complex with RNA [33](pdb:1cvj), and (E) U1A homodimer in com-plex with RNA [29] (pdb:1dz5). ... copies within a protein(44%, two to six RRMs) and ⁄ or together with otherdomains (21%). Among the latter, the most abundantare the zinc ﬁngers of the CCCH and CCHC type(21% of those with an...

Tài liệu Báo cáo khoa học: "Learning to Translate with Multiple Objectives" doc

... weaklypareto-optimal if there is no other hypothesis thatimproves all the metrics; a hypothesis is pareto-optimal if there is no other hypothesis that improvesat least one metric without detriment to other ... A hypothesish∗∈ L is weakly pareto-optimal iff there is no otherhypothesis h ∈ L such that M(h) > M (h∗).Weakly pareto-optimal points are a superset ofpareto-optimal points. A hypothesis ... pareto-optimal.Deﬁnition 1. Pareto Optimal: A hypothesis h∗∈L is pareto-optimal iff there does not exist anotherhypothesis h ∈ L such that M(h)  M(h∗).In Figure 1, the hypotheses indicated by circle(o)...

Tài liệu Báo cáo khoa học: Tet repressor mutants with altered effector binding and allostery docx

... 4-ddma-atc and rescreened forinduction with 0.4 lm atc and without inducer onMacConkey agar plates. We screened 17 600 colonies with mutations in helix a1, 29 840 with mutations inhelix a4 and 3900 ... repres-sion. TetRi2-E15A L17V shows repression to 12.5% with 4-ddma-atc and to 58% with atc, thus showingonly ﬁvefold improved repression with 4-ddma-atc overatc. A similar result is found for ... L60M yield aTetRi2mutant with reduced inducibility. TetRi2-I59VH63Q exhibits a reverse phenotype but only littlespeciﬁcity with fourfold increased corepression with 4-ddma-atc over atc....

Tài liệu Báo cáo khoa học: "Transition-based parsing with Conﬁdence-Weighted Classiﬁcation" pdf

... confidence-weightedclassifiers with transition-based dependency pars-ing yields results comparable with the state-of-the-art results achieved with Support Vector Machines- with faster training and ... feature selection has been used for languagesmarked with an *.curacy a lot. In this section we will compare re-sults obtained with CW-classifiers with the resultsfor the MaltParser from CoNNL-X. ... ex-periments with using CW-classifiers in transition-based parsing.5.1 Online classifiersWe compare CW-classifiers with other online al-gorithms for linear classification. We compare with perceptron...

Tài liệu Báo cáo khoa học: "K-means Clustering with Feature Hashing" docx

... authors also justiﬁed theirmethod by showing that with feature hashing, dot-product is unbiased, and the length of each vectoris well-preserved with high probability under someconditions.Plausibly ... explain in detail. In NLP, features can beoften expediently expressed with strings. For in-stance, a feature ‘the current word ends with -ing’can be expressed as a string cur:end:ing (herewe suppose ... γ−1Ψ−2where 0 < γ <= 1, with probability at least 1 −γ, RSS is additively distortedby .Proof. Note that a hashed feature map φ(h,ξ)is lin-ear, since φ(x) = Mx with a matrix M suchthat...

Tài liệu Báo cáo khoa học: "Answering Opinion Questions with Random Walks on Graphs" docx

... to deal with suchquestions are called opinion QA systems. Re-searchers (Stoyanov et al., 2005) have found thatopinion questions have very different character-istics when compared with fact-based ... the candidate without matching thequestion sentiment (Stoyanov et al., 2005). How-ever, topic and opinion are not independent in re-ality. The opinion words are closely associated with their ... PageRank Performance with varying parameter λ (µ = 0.5)0.220.240.26PR_r PR_F Base_r Base_FF(3)0.120.140.160.180.20 0.2 0.4 0.6 0.8 1ʅFigure 6: Opinion PageRank Performance with varying parameter...

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