sparing critical normal tissue
Báo cáo khoa học: " Radiotherapy of large target volumes in Hodgkin''''s lymphoma: normal tissue sparing capability of forward IMRT versus conventional techniques" docx
... also consider doses to critical organs and the related toxicity rates We found that the FPIMRT technique allows a reduction of normal tissue complication probability in all critical structures other ... for non-uniform normal tissue irradiation: the effective volume method Int J Radiat Oncol Biol Phys 1989, 16:1623-1630 Burman C, Kutcher GJ, Emami B, Goitein M: Fitting of normal tissue tolerance ... better target coverage and critical structures sparing have been recently proposed A sliding window mantle technique [12], using dynamic MLC (dMLC) and electronic tissue compensation, succeeded...
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Báo cáo khoa học: " A 4D IMRT planning method using deformable image registration to improve normal tissue sparing with contemporary delivery techniques" pot
... way, normal structure sparing is maximized as the free-breathing patient undergoes radiotherapy Methods of designing treatment plans with non-uniform dose distributions to achieve better normal tissue ... 4D dose, as shown in figure 2(j), still had enough dose coverage to the target and more normal tissue sparing than that of the ITV approach (figure 2(j) vs figure 2(h)) The derived AppD for the ... plug-in The conventional objectives that are not voxelized can still be used to control normal tissue sparing and target coverage From the treatment planner’s point of view, our method is an...
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Báo cáo khoa học: " 3D-conformal-intensity modulated radiotherapy with compensators for head and neck cancer: clinical results of normal tissue sparing" doc
... spared, green: not to be spared Discussion One important issue of 3D-c-IMRT is normal tissue sparing Among several critical tissues exposed when head and neck cancers are treated the parotid glands ... of fluence profiles to meet the prescribed doses for PTVs and critical normal tissues nearby to be spared Improved parotid gland sparing has been demonstrated after inverse planning compared ... contribution deals with dose characteristics achieved in planning treatment volumes and normal tissue sparing particularly the parotid gland in 3D-c-IMRT for locoregionally advanced squamous...
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Báo cáo toán học: " Effects of internal low-dose irradiation from 131 I on gene expression in normal tissues in Balb/c mice" ppt
... Internal Radiation Dose [MIRD] formalism [19]: ˜ ¯ Dtissue = Atissue × ni Ei × φi /mtissue , where tissue is the cumulated activity during 24 h in the tissue investigated; ni is the probability that ... transcripts were common for the different tissues (Table 4) No single transcript was A regulated in all five tissue types Among the transcripts regulated in more than one tissue, upregulation was more prevalent ... were affected in two or more tissue types (Table 5) The highest number of affected processes in common for two tissue types was observed for the kidney cortex-lung tissue combination and the kidney...
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Báo cáo khoa học: " Normal tissue toxicity after small field hypofractionated stereotactic body radiation" pdf
... absolute dose, in conjunction with the normal tissues being encompassed by lower isodose lines, provides a biologically sound rationale for using SBRT to reduce normal tissue exposure.[7] Radiobiology ... predict in vivo toxicity of normal tissues, in which alteration and/or injury of various cell types is of greater importance than cell survival.[10] Generally, normal tissue effects are more greatly ... migrate into the radioablated tissue from neighboring undamaged tissue SBRT is well suited for the sparing of tumors involving or abutting parallel functioning tissues (i.e kidneys, lung parenchyma...
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Báo cáo khoa học: " Dose reduction to normal tissues as compared to the gross tumor by using intensity modulated radiotherapy in thoracic malignancies" doc
... to the treatment-planning computer through direct cable network Contouring of the tumor and critical normal structures was done by the radiation oncologist with the assistance of a radiologist ... on every CT slice Prescription of dose to the target and defining dose constraints for the critical normal structure such as the lungs, cord, heart etc was done keeping in mind the partial tolerances ... A-mediastinum Soft Tissue Sarcoma (PO)*-right chest wall Non Small cell lung cancer T2N2M0-right upper lobe Non Small cell lung cancer Stage III-left upper lobe with chest wall infiltration Soft Tissue Sarcoma...
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Báo cáo khoa học: " A comparison of mantle versus involved-field radiotherapy for Hodgkin''''s lymphoma: reduction in normal tissue dose and second cancer risk" docx
... [1,5,7,29] and car- Figure Proportional reduction in integral dose to normal tissues Proportional reduction in integral dose to normal tissues Page of 11 (page number not for citation purposes) Radiation ... of tissue receiving ≥ 4Gy) [5,8,22,23] and bilateral lung V5 [22] V30 for the whole heart was also calculated [23] Second cancer risk modeling Given a dose-volume histogram (DVH) for a normal tissue ... evidence [5,7,8] The aims of this study were to quantify the reduction of radiation dose to normal tissues associated with the transition from 35 Gy mantle RT to 35 Gy IFRT to 20 Gy IFRT for...
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Báo cáo y học: "Application of Small Angle X-ray Scattering (SAXS) for Differentiation between Normal and Cancerous Breast Tissue"
... of tissue types: 20 pure adipose tissues, 17 mixed (adipose plus fibroglandular) normal tissues, 41 carcinoma and 21 fibrocystic changes Effects of storage – In order to study the effects of tissue ... histological analysis whilst the remaining tissue was prepared for scatter analysis All measurements were made with the tissue at room temperature and all tissues were stored between measurements ... which the tissue was stored at liquid nitrogen temperatures Results Mean diffraction profiles for the four different tissue types studied in this work are shown in Figure Adipose 119 tissue presents...
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Tài liệu Báo cáo khoa học: Comparison of membrane fraction proteomic profiles of normal and cancerous human colorectal tissues with gel-assisted digestion and iTRAQ labeling mass spectrometry pptx
... of membrane proteins from paired tumoral and adjacent normal tissue of CRC patients A total of eight tumor tissues and eight matched normal tissues were collected from eight CRC patients (Table ... from tumoral and adjacent normal tissues After surgery, paired tumoral and adjacent normal tissues were obtained from the same CRC patient and stored at )80 °C Frozen tissues were unfrozen rapidly ... peptides from the normal tissue of one patient were labeled with iTRAQ114 and peptides from tumor tissue of the same patient were labeled with iTRAQ115 The resulting peptides from normal tissue of another...
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Báo cáo y học: "Differential expression of the angiogenic Tie receptor family in arthritic and normal synovial tissue" doc
... and normal synovial tissues (6%) The inflammatory and vascularity scores were higher in RA synovial tissue in comparison to OA and normal In accordance with the staining data, RA synovial tissue ... expression was significantly higher in RA synovial tissue compared to OA synovial tissue (threefold), normal synovial tissue (9.5-fold) and RA synovial tissue fibroblasts (sixfold) Western blot analysis ... levels were significantly higher in RA synovial tissue compared to OA synovial tissue (1.9-fold), normal synovial tissue (fourfold) and RA synovial tissue fibroblasts (9.6-fold) Tie2 protein expression...
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Báo cáo y học: "Fragmentation of decorin, biglycan, lumican and keratocan is elevated in degenerate human meniscus, knee and hip articular cartilages compared with age-matched macroscopically normal and control tissues" pptx
... Leonards, New South Wales, Australia All tissues, normally discarded at surgery, were obtained with informed consent Menisci (pooled medial and lateral tissue) , knee (pooled femoral and tibial) ... remaining tissue extracts from individual donors/tissues were similarly dialyzed but were not fractionated by centrifugal diafiltration Chondroitinase ABC and keratanase-I digestion of tissue extracts ... distribution of the total knee and hip replacement tissue donors used in this study (b) Pooled tissue extracts were examined by Western blotting Pooled M GuHCl tissue extracts were fractionated by centrifugal...
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Báo cáo y học: "Significance of differential expression of thymidylate synthase in normal and primary tumor tissues from patients with colorectal cancer" ppsx
... tumor cells Thirty of them (39.49%) have showed higher level of TS in primary tumors than in normal tissues To study the significance of the differential expression of TS in primary tumors, clinicopathological ... as: Liu et al.: Significance of differential expression of thymidylate synthase in normal and primary tumor tissues from patients with colorectal cancer Journal of Hematology & Oncology 2011...
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Báo cáo y học: " Histology of adipose tissue inflammation in Dercum’s disease, obesity and normal weight controls: a case control study" doc
... histological appearance of the adipose tissue in DD has been described Fat biopsies in different case reports have revealed histologically normal adipose tissue without inflammation [8,10] However, ... of the nerves in the adipose tissue of the painful sites [1,20], which has only been confirmed in one case report [21] As regards inflammatory signs in the adipose tissue in DD, leukocytes and ... obese, body mass index (BMI)-matched controls and controls with normal BMI Patients and Methods Patients A total of 53 women with adipose tissue pain were recruited to the study All patients were diagnosed...
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Histology of adipose tissue inflammation in Dercum’s disease, obesity and normal weight controls: a case control study pdf
... histological appearance of the adipose tissue in DD has been described Fat biopsies in different case reports have revealed histologically normal adipose tissue without inflammation [8,10] However, ... of the nerves in the adipose tissue of the painful sites [1,20], which has only been confirmed in one case report [21] As regards inflammatory signs in the adipose tissue in DD, leukocytes and ... obese, body mass index (BMI)-matched controls and controls with normal BMI Patients and Methods Patients A total of 53 women with adipose tissue pain were recruited to the study All patients were diagnosed...
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Báo cáo y học: "Quantification of lean and fat tissue repletion following critical illness: a case report" doc
... crossing the tissue This measurement allows partitioning between bone versus soft tissue and fat versus lean tissue in pixels of the body where there is no overlaying calcified tissue The assessment ... perhaps what many in this field had suspected – lean tissue repletion during rehabilitation and recovery from critical illness is minimal Although critically ill patients are a complex patient group, ... if, patients replenish lean tissue lost during critical illness Competing interests The authors declare that they have no competing interests Weight gain following critical illness is largely...
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Báo cáo y học: " Fat tissue and adiponectin: new players in critical care" docx
... have a rethink of the role of fat tissue in the critical state in humans Obviously the authors did not investigate the mechanism of decreased adiponectin in critical illness, as it was not the ... Critical Care Vol 13 No Owecki a well-known defense mechanism against hypotension and stress, whereas ... and being spread throughout the body hormone-producing and cytokine-producing machinery, adipose tissue cannot stand passively by in the face of severe threat to life, and is involved in numerous...
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Báo cáo y học: "Correction: A DNA microarray survey of gene expression in normal human tissues" pdf
... sample mRNA versus normal female genomic DNA, or indirectly by multiplying the ratio of prostate sample mRNA versus common reference mRNA by the ratio of common reference mRNA versus normal female ... transcript level for all expressed genes), calculated indirectly using the common reference mRNA versus normal female genomic DNA hybridization data ...
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BuMP and norMal MaPPIng
... the Normal button to add normal map to the list If other types of maps are listed, click the Remove Map button in the section for the map you want to remove 11 Click the folder next to the Normal ... Tangent Space Normals This tells Maya the texture you’re applying is a normal map and not a bump map You can leave the Bump Depth at 1; it has no effect on the strength of the normal map Switch ... The low-resolution model with all of its normal maps Normal maps are difficult but not impossible to edit in a 2D paint program such as Photoshop If the normal map has just a few small glitches,...
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Critical Systems Specification
... identification Identify the risks faced by the critical system In safety -critical systems, the risks are the hazards that can lead to accidents In security -critical systems, the risks are the potential ... Chapter Slide Risk-driven specification Critical systems specification should be riskdriven This approach has been widely used in safety and security -critical systems The aim of the specification ... ©Ian Sommerville 2004 Software Engineering, 7th edition Chapter Slide 18 Strategy use Normally, in critical systems, a mix of risk reduction strategies are used In a chemical plant control...
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- malignant benign and normal non malignant tissue
- feedback inhibitors in normal and tumor tissues
- typhimurium strains a1 and a1 r in normal tissue in vivo
- 3the aged skeletal muscle niche impairs normal regeneration tgf beta 1 signaling maintains satellite cell quiescence and leads to scar tissue formation
- 5 abnormalities of normal breast tissue in the vicinity of cancers
- genetic alterations in normal and malignant breast tissue
- determination of critical depths and normal depths
- isolation of stem cells from normal and tumor breast tissues
- normal tissue tolerance iort
- normal tissue tolerance to ioert ebrt or both animal and clinical studies
- normal tissue complications and protection in head and neck cancer patients
- the physiology of metabolic tissues under normal and disease states
- use of surrogate tissues nontumor normal tissues in pd studies
- converting 3d dose to biological outcomes tumour control probability tcp and normal tissue complication probability ntcp
- technique target volume and critical normal structure definition
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