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rheumatoid arthritis osteoarthritis and gout

Báo cáo y học:

Báo cáo y học: "Role of RUNX in autoimmune diseases linking rheumatoid arthritis, psoriasis and lupus" pptx

Báo cáo khoa học

... rheumatoid arthritis Nat Genet 2003, 35:341-348 John S, Eyre S, Myerscough A, Barrett J, Silman A, Ollier W, Worthington J: Linkage and association analysis of candidate genes in rheumatoid arthritis ... of the PD1.3 A allelle of the PDCD1 gene in patients with rheumatoid arthritis negative for rheumatoid factor and the shared epitope Arthritis Rheum 2004, 50:1770-1773 Helms C, Cao L, Krueger ... bone formation and repair, and it is of particular interest when considering the susceptibility to response to treatment of patients with rheumatoid arthritis or to disease severity and damage 10...
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Báo cáo y học: "Myocardial dysfunction in rheumatoid arthritis: epidemiology and pathogenesis" pps

Báo cáo khoa học

... failure in rheumatoid arthritis Fewer statistics on incidence and prevalence rates for CHF in patients with RA are available and are derived from a handful of population-based [24-26] and clinic-based ... failure in rheumatoid arthritis: A population-based study over 46 years Arthritis Rheum 2005, 52:412-420 Wolfe F, Michaud K: Heart failure in rheumatoid arthritis: Rates, predictors, and the effect ... metabolic syndrome features in rheumatoid arthritis Arthritis Res 2002, 4:R5 Svenson KLG, Pollare T, Lithell H, Hallgren R: Impaired glucose handling in active rheumatoid- arthritis: Relationship to...
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Báo cáo y học:

Báo cáo y học: " Environmental risk factors differ between rheumatoid arthritis with and without auto-antibodies against cyclic citrullinated peptides" potx

Báo cáo khoa học

... Silman AJ: The pill, parity, and rheumatoid arthritis Arthritis Rheum 1990, 33:782-789 Kay A, Bach F: Subfertility before and after the development of rheumatoid arthritis in women Ann Rheum ... purposes) Arthritis Research & Therapy Vol No Pedersen et al Table (Continued) Tobacco smoking, coffee and alcohol intake, body mass index, physical activity, and pets and risk of rheumatoid arthritis, ... purposes) Table Non-genetic factors and risk of anti-CCP-positive and anti-CCP-negative rheumatoid arthritis, Denmark 1998 to 2003 Anti-CCP-positive rheumatoid arthritis Number of patients/controls...
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Báo cáo y học:

Báo cáo y học: "Contribution for new genetic markers of rheumatoid arthritis activity and severity: sequencing of the tumor necrosis factor-alpha gene promoter" docx

Báo cáo khoa học

... TNF-α gene, between nucleotides -1,318 and +49, of 554 patients with RA from 11 Portuguese rheumatology centers serving the mainland and Azores and Madeira Islands An association was found between ... the 238, -308, -857, and -863 positions, and systemic manifestations, functional status, radiological damage, work disability, and joint surgeries and between haplotypes and radiological damage ... for the classification of rheumatoid arthritis Arthritis Rheum 1988, 31:315-324 Fonseca JE, Canhão H, Reis P, Jesus H, Pereira da Silva JA, Viana Queiroz M: [Rheumatoid arthritis clinical protocol]...
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Báo cáo y học:

Báo cáo y học: "The need for prognosticators in rheumatoid arthritis. Biological and clinical markers: where are we now" potx

Báo cáo khoa học

... the Treatment of Rheumatoid Arthritis of Early Onset Study Group: Combination of infliximab and methotrexate therapy for early rheumatoid arthritis: a randomized, controlled trial Arthritis Rheum ... with rheumatoid arthritis Arthritis Rheum 2004, 50:1390-1399 Landewe RB, Geusens P, Van der Heijde DM, Boers M, van der Linden SJ, Garnero P: Arthritis instantaneously causes collagen type I and ... acute phase proteins in rheumatoid arthritis Scand J Rheumatol Suppl 1994, 100:9-19 Otterness IG: The value of C-reactive protein measurement in rheumatoid arthritis Semin Arthritis Rheum 1994,...
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Báo cáo y học:

Báo cáo y học: "Expression of 5-lipoxygenase and 15-lipoxygenase in rheumatoid arthritis synovium and effects of intraarticular glucocorticoids" docx

Báo cáo khoa học

... Lipoxygenase enzymes in rheumatoid arthritis and osteoarthritis synovial tissue 5-Lipoxygenase (5-LO) and 15-LO-1 enzymes are present in both tissue rheumatoid arthritis (RA) and osteoarthritis (OA) synovial ... synovial tissue and clinical improvement in rheumatoid arthritis Arthritis Rheum 2004, 50:3783-3791 49 Harris ED Jr: Prednisolone in early rheumatoid arthritis: an antiinvasive effect Arthritis Rheum ... expression in rheumatoid arthritis synovial fluid cells and 15-hydroxyeicosatetraenoic acid production Rheumatoid arthritis (RA) production synovial fluid cells express 15-lipoxygenase-1 (15-LO-1) and...
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Báo cáo y học: " CTLA4-Ig interacts with cultured synovial macrophages from rheumatoid arthritis patients and downregulates cytokine production" ppt

Báo cáo khoa học

... in rheumatoid arthritis Clin Exp Rheumatol 2007, 25:S4-11 Miossec P: Dynamic interactions between T cells and dendritic cells and their derived cytokines/chemokines in the rheumatoid synovium Arthritis ... strategy in the treatment of rheumatoid arthritis? Arthritis Res Ther 2005, 7:S15-20 Buch MH, Vital EM, Emery P: Abatacept in the treatment of rheumatoid arthritis Arthritis Res Ther 2008, 10:S5 ... Ther 2008, 10:S2 Olsen NJ, Stein MC: New drugs for rheumatoid arthritis N Engl J Med 2004, 350:2167-2179 Abbott JD, Moreland LW: Rheumatoid arthritis: Developing pharmacological therapies Expert...
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Báo cáo y học:

Báo cáo y học: "α α Upregulated hypoxia inducible factor-1α and -2α pathway in rheumatoid arthritis and osteoarthritis" pps

Báo cáo khoa học

... hypoxia inducible factor; OA, osteoarthritis; RA, rheumatoid arthritis OA RA HIF-2α Overexpression of hypoxia inducible factor (HIF)-1α and HIF-2α in osteoarthritic (OA) and rheumatoid arthritic (RA) ... of a dense, viable and hyperpermeable vascular system RHEUMATOID PATHOLOGY Schematic representation of the suggested pathogenetic model in osteoarthritis (OA) and rheumatoid arthritis (RA) HIF, ... necrosis factor alpha and interleukin-1 in rheumatoid arthritis Arthritis Rheum 1998, 41:1258-1265 38 Szekanecz Z, Kim J, Koch AE: Chemokines and chemokine receptors in rheumatoid arthritis Semin Immunol...
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Báo cáo y học:

Báo cáo y học: "Electrophoretic characterization of species of fibronectin bearing sequences from the N-terminal heparin-binding domain in synovial fluid samples from patients with osteoarthritis and rheumatoid arthritis" doc

Báo cáo khoa học

... fragments and their role in inflammatory arthritis Semin Arthritis Rheum 2000, 29:252265 Peters JH, Loredo GA, Benton HP: Is osteoarthritis a “fibronectin-integrin imbalance disorder”? Osteoarthritis ... osteoarthritis (OA) [3,6–9], and fragmented forms of FN have been detected in synovial fluid (SF) and articular cartilage from patients with OA and patients with rheumatoid arthritis (RA) [10–17] On ... cluster in samples 1, 3, 4, 7, and (diagonal arrows pointing upward and to the left) (2) ~185-kDa (denoted by small brackets facing downward): OA samples and (b,d), and and (f,g) (blots/exposures...
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Báo cáo y học:

Báo cáo y học: "Expression analysis of three isoforms of hyaluronan synthase and hyaluronidase in the synovium of knees in osteoarthritis and rheumatoid arthritis by quantitative real-time reverse transcriptase polymerase chain reaction" potx

Báo cáo khoa học

... hyaluronanof knees in 2, and -3 and hyaluronidase-1, -2, and -3 in the synovium of knees in osteoarthritis (OA) and rheumatoid arthritis (RA) Total RNA was isolated from knee synovium and expression levels ... 2-∆average∆CT Figure osteoarthritis hyaluronidase-1, -2, and -3 in the synovium synthase-1, 2, and -3 and (OA) levels of the messages (RA) Relative expressionand rheumatoid arthritis for hyaluronanof ... HAS-1, -2, and -3 and Available online http:/ /arthritis- research.com/content/6/6/R514 Table Baseline data for subjects with osteoarthritis (OA) or rheumatoid arthritis (RA) or without arthritis...
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Báo cáo y học:

Báo cáo y học: "Tolerability and adverse events in clinical trials of celecoxib in osteoarthritis and rheumatoid arthritis: systematic review and meta-analysis of information from company clinical trial report" potx

Báo cáo khoa học

... R650 Arthritis Research & Therapy Vol No Moore et al Results Trials Clinical reports of 31 randomised trials – 21 in osteoarthritis, in rheumatoid arthritis, and in mixed osteoarthritis or rheumatoid ... maximum daily dose, and rofecoxib was used at 25 mg daily Information for osteoarthritis and rheumatoid arthritis was combined because the number of patients in trials with rheumatoid arthritis was ... review and meta-analysis of celecoxib in osteoarthritis and rheumatoid arthritis was conducted using information from company clinical trial reports, supplied by Pfizer Ltd, of completed randomised,...
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Báo cáo y học:

Báo cáo y học: "Androgen conversion in osteoarthritis and rheumatoid arthritis synoviocytes – androstenedione and testosterone inhibit estrogen formation and favor production of more potent 5α-reduced androgens" ppt

Báo cáo khoa học

... synovial cells of three patients with rheumatoid arthritis (RA) and osteoarthritis (OA), we demonstrated that DHEA can be converted to testosterone, estrone (E1), and 17β-estradiol (E2) [17] In collagen ... substrate OA, osteoarthritis; RA, rheumatoid arthritis Other abbreviations are as given in the legend to Fig dihydrotestosterone, 5α-dihydro-ASD, 6βOH-testosterone, and small quantities of E1 and E2 ... [4-14C]androstenedione (ASD, 4androsten-3,17-dione, 1983.2 MBq/mmol), [4-14C]dehydroepiandrosterone (DHEA, 5-androsten-3β-ol-17-one, 2053 MBq/mmol), or [4-14C]testosterone (testosterone, 4androsten-17β-ol-3-one,...
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Báo cáo y học:

Báo cáo y học: " Decrease in expression of bone morphogenetic proteins 4 and 5 in synovial tissue of patients with osteoarthritis and rheumatoid arthritis" ppt

Báo cáo khoa học

... Differential expression of cathepsins B and L compared with matrix metalloproteinases and their respective inhibitors in rheumatoid arthritis and osteoarthritis: a parallel investigation by semiquantitative ... expressingwith fibrosis in osteoarthritis syno(BMP)-4 (a) and BMP-5 (b) in areas with fibrosis in osteoarthritis synovial tissue (original magnification ×20) Macrophagocytic (white arrows) and fibroblastoid ... experimental osteoarthritis Osteoarthritis Cartilage 2004, 12:627-635 Pagura SM, Thomas SG, Woodhouse LJ, Ezzat S, Marks P: Circulating and synovial levels of IGF-I, cytokines, physical function and anthropometry...
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Báo cáo y học:

Báo cáo y học: "Osteogenic protein 1 in synovial fluid from patients with rheumatoid arthritis or osteoarthritis: relationship with disease and levels of hyaluronan and antigenic keratan sulfate" ppt

Báo cáo khoa học

... from rheumatoid arthritis and osteoarthritis patients and organ donors Representative western blots of syndonors ovial fluid samples from asymptomatic donors (D) and osteoarthritis (OA) and rheumatoid ... markers in SF and joint changes in arthritic diseases [2-7], and have helped to identify markers that may have prognostic and/ or diagnostic value in rheumatoid arthritis (RA) and osteoarthritis (OA) ... asymptomatic donors (donor) and from osteoarthritis (OA) and rheumatoid arthritis (RA) patients detected by an OP-1 sandwich ELISA [19] The data are presented as the mean ± standard error of the mean...
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Báo cáo y học:

Báo cáo y học: "Differential expression of the FAK family kinases in rheumatoid arthritis and osteoarthritis synovial tissues" doc

Báo cáo khoa học

... classification and reporting of osteoarthritis Classification of osteoarthritis of the knee Arthritis Rheum 1986, 29:1039-1049 24 Altman R, Alarcon G, Appelrouth D, Bloch D, Borenstein D, Brandt K, ... citation purposes) Arthritis Research & Therapy Vol No Shahrara et al Figure Rheumatoid arthritis synovial tissue (RA ST) had higher pPyk2 immunopositive cells compared to osteoarthritis (OA) ST ... to 120 Available online http:/ /arthritis- research.com/content/9/5/R112 Figure pSrc is upregulated in rheumatoid arthritis synovial tissue (RA ST) compared to osteoarthritis (OA) ST (a) RA (×200),...
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Báo cáo y học: "Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis" pdf

Báo cáo khoa học

... histories of osteoarthritis and rheumatoid arthritis patients included in the study Osteoarthritis Gender (number) Rheumatoid arthritis Female (18) Male (14) Female (12) Male (1) Mean age ± standard ... from osteoarthritis (n = 5) and rheumatoid arthritis (n = 4) patients FAAH activity (pmol/minute/mg protein) Tissue Control + URB597 Osteoarthritis synovium 2.8 ± 0.46 Undetectable Rheumatoid arthritis ... haematoxylin and eosin micrographs of synovium biopsies taken at osteoarthritis or rheumatoid arthritis total knee arthroplasty (a-c) Osteoarthritis: (a) category (least inflamed), (b) category 2, and...
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Báo cáo y học:

Báo cáo y học: "Gene expression and activity of cartilage degrading glycosidases in human rheumatoid arthritis and osteoarthritis synovial fibroblast" potx

Cao đẳng - Đại học

... vial membrane and fibroblast samples Hc-gp 39, HexA and HexB gene expression in arthritis patients' synovial membrane and fibroblast samples Rheumatoid arthritis (RA) and osteoarthritis (OA) ... β-D-glucuronidase (GusB), hyaluronidase (Hyal1), and klotho genes was lower in rheumatoid arthritis (RA) and osteoarthritis (OA) synovial fibroblasts (SFs) than in RA and OA synovial membrane (SM) tissue ... α-D-mannosidase and β-D-galactosidase in serum and synovial fluid (SFl) of patients with RA and osteoarthritis (OA) On the contrary, SFl exoglycosidases (β-D-N-acetyl-glucosaminidase (NAG) and βD-glucuronidase...
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Báo cáo y học:

Báo cáo y học: "Plasma and synovial fluid microRNAs as potential biomarkers of rheumatoid arthritis and osteoarthritis" pot

Báo cáo khoa học

... classification and reporting of osteoarthritis Classification of osteoarthritis of the knee Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association Arthritis Rheum ... 10.1186/ar3013 Cite this article as: Murata et al., Plasma and synovial fluid microRNAs as potential biomarkers of rheumatoid arthritis and osteoarthritis Arthritis Research & Therapy 2010, 12:R86 Page 14 ... secretions, and menstrual blood [15], and expected to be diagnostic and prognostic biomarkers of various cancers [14,16,17] Several cellular or tissue miRNAs associate with rheumatoid arthritis...
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Báo cáo y học:

Báo cáo y học: " Tumor necrosis factor and norepinephrine lower the levels of human neutrophil peptides 1-3 secretion by mixed synovial tissue cultures in osteoarthritis and rheumatoid arthritis" ppt

Báo cáo khoa học

... Tumor necrosis factor and norepinephrine lower the levels of human neutrophil peptides 1-3 secretion by mixed synovial tissue cultures in osteoarthritis and rheumatoid arthritis Arthritis Research ... tissue/cells and density of synovial neutrophils (a) Levels of human neutrophil peptides 1-3 (HNP1-3) in superfusate of synovial tissue of two patients with rheumatoid arthritis (RA) and osteoarthritis ... Figure Influence of norepinephrine (NE) and cortisol (Cort) on human neutrophil peptides 1-3 (HNP1-3) levels in patients with rheumatoid arthritis (RA) and osteoarthritis (OA) (a, b) Influence of...
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