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sle and rheumatoid arthritis

Báo cáo y học:

Báo cáo y học: "Women, men, and rheumatoid arthritis: analyses of disease activity, disease characteristics, and treatments in the QUEST-RA Study" ppsx

Báo cáo khoa học

... seventy-five rheumatoid arthritis patients studied over nine years Arthritis Rheum 1984, 27:864-872 Kaarela K: Prognostic factors and diagnostic criteria in early rheumatoid arthritis Scand J Rheumatol ... with rheumatoid arthritis and the general population Ann Rheum Dis 2004, 63:494-497 Katz PP, Criswell LA: Differences in symptom reports between men and women with rheumatoid arthritis Arthritis ... Swedish patients with rheumatoid arthritis in 1995 compared with 1978 Scand J Rheumatol 1999, 28:160-165 Pincus T, Sokka T, Kautiainen H: Patients seen for standard rheumatoid arthritis care have...
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Báo cáo y học:

Báo cáo y học: "Electrophoretic characterization of species of fibronectin bearing sequences from the N-terminal heparin-binding domain in synovial fluid samples from patients with osteoarthritis and rheumatoid arthritis" doc

Báo cáo khoa học

... osteoarthritis (OA) [3,6–9], and fragmented forms of FN have been detected in synovial fluid (SF) and articular cartilage from patients with OA and patients with rheumatoid arthritis (RA) [10–17] On ... cluster in samples 1, 3, 4, 7, and (diagonal arrows pointing upward and to the left) (2) ~185-kDa (denoted by small brackets facing downward): OA samples and (b,d), and and (f,g) (blots/exposures ... 1, 3, 4, 7, and 8, as well as RA samples 11–15 (denoted by diagonal arrows pointing upward and to the left in Figs and 5; Table 1) In of the OA samples (1 and in Fig 4, also samples and in blots...
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Báo cáo y học:

Báo cáo y học: "Citrullination, a possible functional link between susceptibility genes and rheumatoid arthritis" ppsx

Báo cáo khoa học

... quantitative genetic contribution to rheumatoid arthritis using data from twins Arthritis Rheum 2000, 43:30-37 Gabriel SE: The epidemiology of rheumatoid arthritis Rheum Dis Clin North Am 2001, ... specificity and structural relationships of the natural substrates trichohyalin and filaggrin J Biol Chem 1996, 271: 30709-30716 Utz PJ, Gensler TJ, Anderson P: Death, autoantigen modifications, and ... Death, autoantigen modifications, and tolerance Arthritis Res 2000, 2:101-114 Silman AJ, Pearson JE: Epidemiology and genetics of rheumatoid arthritis Arthritis Res 2002, 4(Suppl 3):S265-S272 Hill...
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Báo cáo y học:

Báo cáo y học: "Expression analysis of three isoforms of hyaluronan synthase and hyaluronidase in the synovium of knees in osteoarthritis and rheumatoid arthritis by quantitative real-time reverse transcriptase polymerase chain reaction" potx

Báo cáo khoa học

... osteoarthritis hyaluronidase-1, -2, and -3 in the synovium synthase-1, 2, and -3 and (OA) levels of the messages (RA) Relative expressionand rheumatoid arthritis for hyaluronanof knees in 2, and ... HAS-1, -2, and -3 and Available online http:/ /arthritis- research.com/content/6/6/R514 Table Baseline data for subjects with osteoarthritis (OA) or rheumatoid arthritis (RA) or without arthritis ... knees in 2, and -3 and hyaluronidase-1, -2, and -3 in the synovium of knees in osteoarthritis (OA) and rheumatoid arthritis (RA) Total RNA was isolated from knee synovium and expression levels...
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Báo cáo y học:

Báo cáo y học: "Tolerability and adverse events in clinical trials of celecoxib in osteoarthritis and rheumatoid arthritis: systematic review and meta-analysis of information from company clinical trial report" potx

Báo cáo khoa học

... R650 Arthritis Research & Therapy Vol No Moore et al Results Trials Clinical reports of 31 randomised trials – 21 in osteoarthritis, in rheumatoid arthritis, and in mixed osteoarthritis or rheumatoid ... maximum daily dose, and rofecoxib was used at 25 mg daily Information for osteoarthritis and rheumatoid arthritis was combined because the number of patients in trials with rheumatoid arthritis was ... review and meta-analysis of celecoxib in osteoarthritis and rheumatoid arthritis was conducted using information from company clinical trial reports, supplied by Pfizer Ltd, of completed randomised,...
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Báo cáo y học:

Báo cáo y học: "Natural killer T cells and rheumatoid arthritis: friend or foe" ppt

Báo cáo khoa học

... terminal effector mechanisms of RA The development of antibody-induced arthritis was first examined in Jα18–/– and CD1d–/– mice and was found to be less severe compared to wild-type controls In addition, ... to healthy mice causes inflammatory arthritis by deposition of autoantibody in joint spaces, inducing an inflammatory cascade with activation of complement and Fcγ receptor pathways [14] This ... Available online http:/ /arthritis- research.com/content/7/2/88 NKT cells in antibody-induced arthritis in the K/BxN serum transfer model [13] Transfer of serum...
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Báo cáo y học:

Báo cáo y học: "Androgen conversion in osteoarthritis and rheumatoid arthritis synoviocytes – androstenedione and testosterone inhibit estrogen formation and favor production of more potent 5α-reduced androgens" ppt

Báo cáo khoa học

... synovial cells of three patients with rheumatoid arthritis (RA) and osteoarthritis (OA), we demonstrated that DHEA can be converted to testosterone, estrone (E1), and 17β-estradiol (E2) [17] In collagen ... [4-14C]androstenedione (ASD, 4androsten-3,17-dione, 1983.2 MBq/mmol), [4-14C]dehydroepiandrosterone (DHEA, 5-androsten-3β-ol-17-one, 2053 MBq/mmol), or [4-14C]testosterone (testosterone, 4androsten-17β-ol-3-one, ... OA, osteoarthritis; RA, rheumatoid arthritis Other abbreviations are as given in the legend to Fig dihydrotestosterone, 5α-dihydro-ASD, 6βOH-testosterone, and small quantities of E1 and E2 (Fig...
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Báo cáo y học:

Báo cáo y học: "Association between occupational exposure to mineral oil and rheumatoid arthritis: results from the Swedish EIRA case–control study" docx

Báo cáo khoa học

... developing collagen- and oil-induced arthritis Scand J Immunol 1995, 42:128-134 29 Svelander L, Mussener A, Erlandsson-Harris H, Kleinau S: Polyclonal Th1 cells transfer oil-induced arthritis Immunology ... risk and 95% confidence interval for developing rheumatoid factor (RF)-positive rheumatoid arthritis (RA), RF- RA, antibodies to citrullinecontaining peptides (anti-CP)-positive RA, anti-CP- RA and ... Investigation of Rheumatoid Artrhitis study group consists of: Ingeli Andréasson, Landvetter; Eva Baecklund, Akademiska Hospital; Ann Bengtsson and Thomas Skogh, Linköping Hospital; Johan Bratt and Ingiäld...
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Báo cáo y học:

Báo cáo y học: "Enumeration and phenotypical analysis of distinct dendritic cell subsets in psoriatic arthritis and rheumatoid arthritis" pps

Báo cáo khoa học

... quantify and characterise the distribution and phenotype of mDCs and pDCs in blood from PsA patients and RA patients in comparison with osteoarthritis (OA) patients and healthy donors and synovial ... (×104/ml) in rheumatoid arthritis and psoriatic arthritis peripheral blood and matched synovial fluid White blood cells Myeloid dendritic cells Plasmacytoid dendritic cells Rheumatoid arthritis ... subsets Rheumatoid arthritis (RA) and psoriatic arthritis (PsA) peripheral blood (PB) plasmacytoid DC subsets dendritic cells (pDCs) and myeloid dendritic cells (mDCs) have an immature phenotype and...
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Báo cáo y học:

Báo cáo y học: "Epstein–Barr virus and rheumatoid arthritis: is there a link''''" docx

Báo cáo khoa học

... the annual and longterm direct costs of rheumatoid arthritis: the impact of poor function and functional decline Arthritis Rheum 1999, 42: 1209-1218 McIntosh E: The cost of rheumatoid arthritis ... mortality of rheumatoid arthritis Arthritis Rheum 1994, 37:481-494 Pincus T, Callahan LF: Taking mortality in rheumatoid arthritis seriously—predictive markers, socioeconomic status and comorbidity ... proliferation in patients with rheumatoid arthritis and their unaffected siblings Arthritis Rheum 1996, 39:904913 Kotzin BL: The role of B cells in the pathogenesis of rheumatoid arthritis J Rheumatol...
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Báo cáo y học:

Báo cáo y học: " Decrease in expression of bone morphogenetic proteins 4 and 5 in synovial tissue of patients with osteoarthritis and rheumatoid arthritis" ppt

Báo cáo khoa học

... Differential expression of cathepsins B and L compared with matrix metalloproteinases and their respective inhibitors in rheumatoid arthritis and osteoarthritis: a parallel investigation by semiquantitative ... A similar distribution and predominant expression of different BMPs in fibroblastoid and macrophagocytic cells was also shown by Lories and colleagues [18] and van Lent and colleagues [26] That ... recruitment and performed the 'synovitis score' AP and CK conducted part of the patient recruitment and data evaluation FS, GAM and GRB provided substantial input into data evaluation All authors read and...
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Báo cáo y học:

Báo cáo y học: "What determines the evolution of early undifferentiated arthritis and rheumatoid arthritis? An update from the Norfolk Arthritis Register" ppt

Báo cáo khoa học

... Classification of inflammatory polyarthritis and rheumatoid arthritis When NOAR was initially established, its aim was to study the natural history of rheumatoid arthritis (RA) The net was deliberately ... Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis Arthritis Rheum 1995, 38:44-48 van Gestel AM, Haagsma CJ, van Riel PL: Validation of rheumatoid arthritis ... classification of rheumatoid arthritis Arthritis Rheum 1988, 31:315-324 Wiles N, Symmons DPM, Harrison B, Barrett E, Barrett JH, Scott DGI, Silman AJ: Estimating the incidence of rheumatoid arthritis: ...
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Báo cáo y học:

Báo cáo y học: "Differential effects on BAFF and APRIL levels in rituximab-treated patients with systemic lupus erythematosus and rheumatoid arthritis" pot

Báo cáo khoa học

... organs [6] and is inducible by cells of myeloid origin (monocytes, macrophages, neutrophils, and dendritic cells) and also by osteoclasts (reviewed by Ng and colleagues [3] and Dillon and colleagues ... BAFF and APRIL in patients with SLE and RA In this context, already at baseline, our cohort of patients with SLE were treated with cyclophosphamide and our patients with RA with methotrexate and/ or ... design, acquired, analysed and interpreted data, prepared the manuscript, and performed statistical analysis MH and IG selected and collected samples and interpreted and provided clinical data...
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Báo cáo y học:

Báo cáo y học: "Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis" pdf

Báo cáo khoa học

... of osteoarthritis and rheumatoid arthritis patients included in the study Osteoarthritis Gender (number) Rheumatoid arthritis Female (18) Male (14) Female (12) Male (1) Mean age ± standard deviation, ... ethanolamide (PEA) ,and rheumatoid arthritis (RA) (n = synovial fluid of non-inflamed normal volunteers (control) (n = 6) and of patients with osteoarthritis (OA) (n = 14) and rheumatoid arthritis (RA) ... synovium tissue and synovial fluid in normal, osteoarthritis, and rheumatoid arthritis samples The synovial tissue from OA and RA patients was used to measure endocannabinoid and entourage compounds...
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Báo cáo y học:

Báo cáo y học: "The relationship between cancer and rheumatoid arthritis: still a large research agenda" ppsx

Báo cáo khoa học

... Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: systematic review and meta-analysis of rare harmful effects in randomized controlled trials JAMA ... between rheumatoid arthritis and malignancy Rheum Dis Clin North Am 2004, 30:271-284, vi Bongartz T, Sutton AJ, Sweeting MJ, Buchan I, Matteson EL, Montori V: Anti-TNF antibody therapy in rheumatoid ... NIH (AR 047782 and AR055989) References Smitten AL, Simon TA, Hochberg MC, Suissa S: A meta-analysis of the incidence of malignancy in adult patients with rheumatoid arthritis Arthritis Res Ther...
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Báo cáo y học:

Báo cáo y học: "Lack of association or interactions between the IL-4, IL-4Rα and IL-13 genes, and rheumatoid arthritis" pptx

Báo cáo khoa học

... antibodies and rheumatoid factor with radiographic severity of rheumatoid arthritis Arthritis Res Ther 2006, 8:R128 10 Larsen A: How to apply Larsen score in evaluating radiographs of rheumatoid arthritis ... of Rheumatoid Arthritis, GORA) and the Arthritis Research Campaign References Wellcome Trust Case Control Consortium: Genome-wide association study of 14,000 cases of seven common diseases and ... odds ratio; RA, rheumatoid arthritis Page of (page number not for citation purposes) Arthritis Research & Therapy Vol 10 No Marinou et al Table The extend of LD across the IL-13 and IL-4 genes...
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Báo cáo y học:

Báo cáo y học: "κ The roles of the classical and alternative nuclear factor-κB pathways: potential implications for autoimmunity and rheumatoid arthritis" ppsx

Báo cáo khoa học

... between IL-17 and TNF-α below) [94,95] Activated macrophages also produce IL-6 and IL-1 IL-6 (and by some accounts IL-1, TNF-α and IL-17), in addition to Toll-like receptor-2 and -4 ligands, directly ... including immunity and cell development [82,83] κ The T-helper-17/IL-17/nuclear factor-κB axis in rheumatoid arthritis Continued inflammation and the resulting destruction of bone and cartilage in ... guiding the survival and differentiation of developing B and T lymphocytes [21,22] These are summarized in Figures and Brief summaries of positive and negative selection of B and T cells follow...
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Báo cáo y học:

Báo cáo y học: "Altered lipoprotein metabolism in chronic inflammatory states: proinflammatory high-density lipoprotein and accelerated atherosclerosis in systemic lupus erythematosus and rheumatoid arthritis" ppsx

Báo cáo khoa học

... erythematosus and rheumatoid arthritis Arthritis Rheum 2006, 54:2541-2549 56 del Rincón ID, Williams K, Stern MP, Freeman GL, Escalante A: High incidence of cardiovascular events in a rheumatoid arthritis ... atherosclerosis in SLE and RA becomes apparent In our studies [55], the presence of piHDLs was common in SLE and a strong predictor of subclinical atherosclerosis A study of 154 women with SLE compared ... lipoproteins (HDLs) isolated from healthy controls (left column) and patients with systemic lupus erythematosus (SLE) (middle column) and rheumatoid arthritis (RA) (right column) Numbers below 1.0 are normal;...
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Báo cáo y học:

Báo cáo y học: "Women, men, and rheumatoid arthritis: analyses of disease activity, disease characteristics, and treatments in the QUEST-RA Study" potx

Báo cáo khoa học

... seventy-five rheumatoid arthritis patients studied over nine years Arthritis Rheum 1984, 27:864-872 Kaarela K: Prognostic factors and diagnostic criteria in early rheumatoid arthritis Scand J Rheumatol ... with rheumatoid arthritis and the general population Ann Rheum Dis 2004, 63:494-497 Katz PP, Criswell LA: Differences in symptom reports between men and women with rheumatoid arthritis Arthritis ... Swedish patients with rheumatoid arthritis in 1995 compared with 1978 Scand J Rheumatol 1999, 28:160-165 Pincus T, Sokka T, Kautiainen H: Patients seen for standard rheumatoid arthritis care have...
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