potential for intervention in stress related allergic diseases
Báo cáo lâm nghiệp: "High potential for increase in CO2 flux from forest soil surface due to global warming in cooler areas of Japan" ppt
... obtained by incubation method RESULTS 3.1 CO2 flux from the forest floor The CO2 flux from the forest floor fluctuated seasonally, showing maximum in summer and minimum in winter The CO2 fluxes during ... S., Takahashi M., A method for measuring fluxes of greenhouse gases from forest soils, Bull For For Prod Res Inst 392 (2004) 259–265 [25] Schlesinger W.H., Carbon balance in terrestrial detritus, ... measured using an NC analyzer (NC-800, Sumitomo Chemical Co., Japan) The inorganic NH4 and NO3 in the extractant of 10 g fresh soil shaken with 100 mL 2M KCl for h were determined using a flow-injection...
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Báo cáo y học: "Diagnostic evaluation of food-related allergic diseases" docx
... discussed first before exploring the specific details of food allergen skin testing Extensive variability exists in skin prick test devices, skin testing techniques used, and the grading and interpretation ... Diagnosing peanut allergy with skin prick and specific IgE testing J Allergy Clin Immunol 2005, 115:1291-6 Sporik R, Hill DJ, Hosking CS: Specificity of allergen skin testing in predicting positive ... been providing clinical data to clinicians in Europe for several years, but is not yet cleared by North American regulatory agencies for clinical use Historically, specific IgE testing has been...
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Prevalence and risk factors for refractive errors and their associations with major age related eye diseases in adult singapore indians
... 12 Housing Type in the Singapore Indian Eye Study…………………… 202 Figure 13 Individual Monthly Income in the Singapore Indian Eye Study………203 Figure 14 Smoking Categories in the Singapore Indian ... Length in Population-Based Studies The means of AL adults were reported to be 23.23 mm in Singapore Chinese17, 23.55 mm in Singapore Malays92, 22.6 mm in India Indians117, 23.38 mm in Latinos18, ... Weight in the Singapore Indian Eye Study.205 Figure 16 Distribution of Blood Pressure in the Singapore Indian Eye Study… 206 Figure 17 Distribution of Intraocular Pressure in the Singapore Indian...
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The study of gene and protein vaccines for allergic diseases in mice
... model of allergic asthma that closely resembled human asthma is important as they contribute in gaining insights into the pathogenesis of allergy and in defining the potential strategies for therapeutic ... studies indicated that CD4 T lymphocytes were the primary responding cells in these assays These responses were maintained in vaccines for at least a year (longest time point tested), indicating ... immunosorbent assay hour(s) interfereon Immunoglobulin interleukin intramuscular intraperitoneal liter monoclonal antibody minute(s) optical density phosphate buffered saline polymerase chain reaction paranitrophenyl...
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Tài liệu Báo cáo khoa học: Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases pptx
... ANGPTLs in obesity and related metabolic diseases T Kadomatsu et al characterized by a coiled-coil domain in the N-terminus and a fibrinogen-like domain in the C-terminus Angiopoietins have a ... circulating ANGPTL2 may also function in obesity -related insulin resistance but also obesity -related or unrelated cardiovascular disease Interestingly, the circulating ANGPTL2 concentration in patients ... cardiovascular disease in an autocrine or paracrine manner Blocking ANGPTL2 signaling may also be beneficial also in preventing and treating cardiovascular disease (Fig 1) To date, integrins have been...
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Báo cáo khoa học: The calcium-binding domain of the stress protein SEP53 is required for survival in response to deoxycholic acid-mediated injury pdf
... plated in media containing Geneticin to select for cell containing vector DNA (as in Fig 5A,G) After three weeks, the number of cells was determined by fixing cells and staining with dye Individual ... plated in media containing Geneticin to select for cell containing vector DNA After three weeks, the number of cells were determined by fixing cells and staining with dye and quantified in (H) ... minimizing cell injury and maintaining tissue integrity in response to damaging levels of an environmental agent As such, the integrity of this system plays a role in modifying progression of diseases...
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Allergic Diseases – Highlights in the Clinic, Mechanisms and Treatment Edited by Celso Pereira docx
... me for successfully enduring this ordeal yet again In my humble opinion, Allergic diseases - highlights in the clinic, mechanisms and treatment represents a shining example of a productive international ... determination of individual protein concentrations present in the biological sample being investigated, whereas functional proteomic determines constituent proteinprotein, protein-DNA, and protein-RNA ... generations, constituting a heritable change (Baye et al., 2010) The role of epigenetic in diseases, and specifically in allergic diseases is becoming increasingly evident (review in Kumar et al.,...
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báo cáo hóa học:" Social care and changes in occupational accidents and diseases - the situation in Eastern Europe in general and for skin diseases in particular" pptx
... differences in the definition of insurance groups, including the level of the insurance premia and who has to pay these, in the guaranteed payments for total and partial invalidity and in additional ... Labour Inspectorate Social Insurance Institute Belarus Ministry of Health Ministry of Labour Ministry of Statistics Bosnia-Herzegovina Ministry of Health Federation of Bosnia and Herzegovina Ministry ... Full invalidity: from 40% Slovenia No independent insurance Risks are covered by sickness, invalidity and dependent insurance All employees; Students, trainees, handicapped persons during training,...
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ALLERGIC DISEASES – HIGHLIGHTS IN THE CLINIC, MECHANISMS AND TREATMENT potx
... me for successfully enduring this ordeal yet again In my humble opinion, Allergic diseases - highlights in the clinic, mechanisms and treatment represents a shining example of a productive international ... determination of individual protein concentrations present in the biological sample being investigated, whereas functional proteomic determines constituent proteinprotein, protein-DNA, and protein-RNA ... generations, constituting a heritable change (Baye et al., 2010) The role of epigenetic in diseases, and specifically in allergic diseases is becoming increasingly evident (review in Kumar et al.,...
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In silico drug discovery on computational Grids for finding novel drugs against neglected diseases
... preparing the binding site of the protein by taking ~6–8 °A from the co-crystallized ligand, taking care the significant amino acids for the activity are included in the binding site Information ... Gametocytes 4- Amino Quinolines Chloroquine, Amidoquine Intra-erythrocytic stages, Gametocytes Quinoline-alcohols Quinine, Mefloquine Erythrocytic stages Aryl-alcohols Halofrantine, Pyronaridine Erythrocytic ... MM-PBSA scoring against plasmepsin docking conformations 109 Figure 31: MM-GBSA scoring against plasmepsin docking conformations 110 Figure 32: Analysis procedure employed for final selection...
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Báo cáo y học: "The role of Probiotics in allergic diseases" pptx
... probiotics in allergic disorders The interest in probiotic therapeutic potential in allergic disorders stemmed from the fact that they have been shown to reduce inflammatory cytokines and improve intestinal ... intestinal permeability in vitro Such effects would be desirable in treating allergic disorders Therefore, several studies have been designed to examine the efficacy of probiotics in many allergic ... number not for citation purposes) Allergy, Asthma & Clinical Immunology 2009, 5:5 c) The role of probiotics in Allergic Rhinitis Reports on the efficacy of probiotics in treating allergic rhinitis...
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Báo cáo y học: "The potential of human regulatory T cells generated ex vivo as a treatment for lupus and other chronic inflammatory diseases" pot
... Weiner HL, Hafler DA: Induction of circulating myelin basic protein and proteolipid protein-specific transforming growth factor-beta1secreting Th3 T cells by oral administration of myelin in ... agents now in use This treatment is especially promising in autoimmune diseases characterized by a relapsing and remitting course such as SLE, inflammatory bowel disease or certain forms of multiple ... production, depending on how they are activated In each case, regulatory function depends on the cytokines produced [33] In determining the T-cell response to myelin basic protein, another group...
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Báo cáo lâm nghiệp: "Diagnosing plant water status as a tool for quantifying water stress on a regional basis in Mediterranean drylands" pdf
... water saving This appeared to be true also in the case of Q coccifera growing in different areas of Turkey In fact, when growing in degraded sites, this species reduced gL, thus maintaining high ... corrected for large differences in this variable Diagnosing plant water status in Mediterranean drylands -Ψmin, MPa tance strategy was adopted by this species growing in Turkey in that plants combined ... impressively increasing impacts of water stress in more degraded areas (sites D) with respect to those growing in the reference site H When Ψpd, Ψmin and ∆Ψ (= Ψpd – Ψmin), were plotted versus WSIS, linear...
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Báo cáo y học: "Potential involvement of oxidative stress in cartilage senescence and development of osteoarthritis: oxidative stress induces chondrocyte telomere instability and downregulation of chondrocyte function" pptx
... stimuli with ageing and exhibit an age -related decline in response to growth factors such as the anabolic cytokine insulin-like growth factor-I [6] These findings provide evidence supporting the concept ... standard histological procedures For nitrotyrosine staining, the sections were deparaffinized and hydrated, and then were immunostained using antibody for nitrotyrosine in accordance with the method ... immunohistochemical staining for nitrotyrosine in the articular cartilage from an OA patient (female, 67 years old) Immunostaining for nitrotyrosine was most apparent in the degenerated regions...
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Báo cáo y học: " Is interleukin-1 a good target for therapeutic intervention in intervertebral disc degeneration: lessons from the osteoarthritic experience" pdf
... improvement in clinical indicators of pain and disease activity A first randomized controlled trial in patients with knee OA demonstrated a good safety profile for one intra-articular injection ... performed β in osteoarthritis with IL-1β blockers? It is indeed tempting to compare IVD degeneration to OA because the profile of cytokine production in human IVDs looks like the one observed in ... We performed a multicenter, randomized, double-blind, placebo-controlled study to evaluate the clinical response, safety, and tolerability of a single intra-articular injection of anakinra (50...
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Báo cáo y học: "Identification of possible candidate genes regulating Sjögren''''s syndrome-associated autoimmunity: a potential role for TNFSF4 in autoimmune exocrinopathy" docx
... Acknowledgements We thank Robert Haynes for the countless hours spent in caring for and maintaining precise records of these RI lines and Sung Kim for his help in analyzing the function and pathway associations ... region (RI lines 02 and 03) During the subsequent inbreeding, we were successful in generating 39 new homozygous Aec2 RI lines To map each genetic segment of the Aec2 region remaining within each ... fixed in 10% formalin, embedded in paraffin, and sectioned and stained with hematoxylin and eosin (H&E) dye Representative H&E-stained histological sections of lacrimal glands of selected recombinant...
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báo cáo khoa học: "Data for improvement and clinical excellence: protocol for an audit with feedback intervention in long-term care" ppt
... application of RAI data to continuing care settings in Alberta Settings and sample The settings are nine LTC nursing units in four facilities or nursing homes (NHs) in Edmonton, Alberta, Canada ... the intervention We have discussed the rationale for measuring intent to change behavior earlier Including intent to change behavior as an intermediate process outcome will assist in assessing ... provided single point in time comparisons for each unit compared to the combined other eight units After the first monthly report, we began showing data as monthly points with a trend line joining...
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Báo cáo y học: " Hydrodebridement of wounds: effectiveness in reducing wound bacterial contamination and potential for air bacterial contaminatio" pptx
... remove residual water before allowing drying Gold was used as a sputter coating before being mounted for viewing on the SEM Specimen inoculation On completion of baseline sampling the artificial wounds ... undergone training in the theory and practise of the Versajet in a clinical setting During debridement the operator wore gloves, plastic apron, bonnet, visor and mask for protection against contamination ... electron microscopy were fixed in 10% neutral buffered formalin for 48 hours to kill any bacteria The formalin was removed by washing in distilled water then passing through various concentrations...
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báo cáo khoa học: "Activation of stress-related signalling pathway in human cells upon SiO2 nanoparticles exposure as an early indicator of cytotoxicity" pps
... clinical medicine, Institute of Molecular Medicine, Trinity College Dublin, Dublin8, Ireland 2Centre for Research on Adaptive Nanostructures and Nanodevices (CRANN), Naughton Institute, Trinity ... ranging from 15 minutes to 24 h in a 37°C incubator with 5% CO2 Then, cells were washed in phosphate-buffered saline solution (PBS) at pH 7.4 and fixed in 3% paraformaldehyde (PFA) For the 4°C assay, ... allows changes in lysosomal physiology to be determined For instance, an increase or decrease in ph of acidic organelles and the changes in lysosome numbers by compound toxicity results in a decrease...
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báo cáo khoa học: " Characterization of singlet oxygen-accumulating mutants isolated in a screen for altered oxidative stress response in Chlamydomonas reinhardtii" ppsx
... found in strains 35H11 and 18F6 (Figure 2), indicating that mutations in a single nuclear gene is responsible for the increased GPXH expression in each case The same was true for 21B4 except for ... been found to be involved in NPQ in Chlamydomonas reinhardtii indicating that other unidentified components might function in photoprotection and prevention of 1O2 formation in photosynthetic ... strongly induced by the increased production of 1O2 in the chloroplast To identify components affecting 1O2-induced gene expression in C reinhardtii, a mutant screen was performed using the GPXH-arylsulfatase...
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