Thông tin tài liệu
ALLERGIC DISEASES –
HIGHLIGHTS IN THE CLINIC,
MECHANISMS AND
TREATMENT
Edited by Celso Pereira
Allergic Diseases – Highlights in the Clinic, Mechanisms and Treatment
Edited by Celso Pereira
Published by InTech
Janeza Trdine 9, 51000 Rijeka, Croatia
Copyright © 2012 InTech
All chapters are Open Access distributed under the Creative Commons Attribution 3.0
license, which allows users to download, copy and build upon published articles even for
commercial purposes, as long as the author and publisher are properly credited, which
ensures maximum dissemination and a wider impact of our publications. After this work
has been published by InTech, authors have the right to republish it, in whole or part, in
any publication of which they are the author, and to make other personal use of the
work. Any republication, referencing or personal use of the work must explicitly identify
the original source.
As for readers, this license allows users to download, copy and build upon published
chapters even for commercial purposes, as long as the author and publisher are properly
credited, which ensures maximum dissemination and a wider impact of our publications.
Notice
Statements and opinions expressed in the chapters are these of the individual contributors
and not necessarily those of the editors or publisher. No responsibility is accepted for the
accuracy of information contained in the published chapters. The publisher assumes no
responsibility for any damage or injury to persons or property arising out of the use of any
materials, instructions, methods or ideas contained in the book.
Publishing Process Manager Molly Kaliman
Technical Editor Teodora Smiljanic
Cover Designer InTech Design Team
First published March, 2012
Printed in Croatia
A free online edition of this book is available at www.intechopen.com
Additional hard copies can be obtained from orders@intechweb.org
Allergic Diseases – Highlights in the Clinic, Mechanisms and Treatment,
Edited by Celso Pereira
p. cm.
ISBN 978-953-51-0227-4
Contents
Preface IX
Part 1 Allergens, Inflammation and Basic Mechanisms 1
New Challenges for Old Diseases: The Impact of -Omics
Chapter 1
Technologies in the Understanding of Allergic Diseases 3
Blanca Cárdaba, Miriam Aguerri, David Calzada and Carlos Lahoz
Expression of the Histamine H
4
Receptor
in
Human
Tissue 31
Chapter 2
Katsunori Yamaura, Masahiko Suzuki,
Takao Namiki and Koichi Ueno
The Type I and Type II Receptor
Chapter 3
Complexes for IL-4 and IL-13 Differentially
Regulate Allergic Lung Inflammation 43
Nicola M. Heller, Preeta Dasgupta, Nicolas J. Dorsey,
Svetlana P. Chapoval and Achsah D. Keegan
Enzymatic and Chemical Modifications of Food Allergens 83
Chapter 4
Dragana Stanić-Vučinić
and Tanja Ćirković Veličković
Characterization of Seafood
Chapter 5
Proteins Causing Allergic Diseases 107
Anas M. Abdel Rahman, Robert J. Helleur,
Mohamed F. Jeebhay and Andreas L. Lopata
Birch Pollen-Related Food Allergy: An Excellent Disease
Chapter 6
Model to Understand the Relevance of Immunological
Cross-Reactivity for Allergy 141
Brinda Subbarayal, Marija Geroldinger-Simic and Barbara Bohle
Part 2 Clinical Allergy 165
Anaphylaxis: Etiology, Clinical
Chapter 7
Manifestations, Diagnosis and Management 167
Aslı Gelincik and Suna Büyüköztürk
VI
Contents
Allergic Airway Inflammation 195
Chapter 8
Gabriel Morán, Claudio Henriquez
and Hugo Folch
Asthma and Sensitization Pattern in Children 209
Chapter 9
Ute Langen
Wheezing Infant 231
Chapter 10
Yukinori Yoshida, Tomoshige Matsumoto,
Makoto Kameda, Tomoki Nishikido,
Isamu Takamatsu and Satoru Doi
Comorbidities of Allergic Rhinitis 239
Chapter 11
Doo Hee Han and Chae-Seo Rhee
Allergy and Benign Lesions of the Vocal Cord Mucosa 255
Chapter 12
Alenka Kravos
Drug Hypersensitivity 261
Chapter 13
María L. Sanz, Cristobalina Mayorga,
Ruben Martínez-Aranguren and Pedro M. Gamboa
Diagnosis and Management of
Chapter 14
Cows’ Milk Protein Allergy in Infants 279
Elisabeth De Greef, Gigi Veereman-Wauters,
Thierry Devreker, Bruno Hauser and Yvan Vandenplas
Natural Rubber Latex Allergy 289
Chapter 15
Ana Maria Sell and Jeane Eliete Laguila Visentainer
Part 3 Specific Aspects of Allergic Diseases 311
Psychological Factors in Asthma
Chapter 16
and Psychoeducational Interventions 313
Lia Fernandes
Obesity, Diet, Exercise and Asthma in Children 339
Chapter 17
Luis Garcia-Marcos and Manuel Sanchez-Solis
Asthma and Health Related Quality
Chapter 18
of Life in Childhood and Adolescence 365
Esther Hafkamp-de Groen and Hein Raat
Part 4 Treatment Strategies 373
Specific Immunotherapy and
Chapter 19
Central Immune System 375
Celso Pereira, Graça Loureiro,
Beatriz Tavares and Filomena Botelho
Contents VII
β
2
-Adrenoceptor Agonists and Allergic Disease:
Chapter 20
The Enhancing Effect of β
2
-Adrenoceptor
Agonists on Cytokine-Induced TSLP Production
by Human Lung Tissue Cells 403
Akio Matsuda and Kyoko Futamura
Microbiota and Allergy: From Dysbiosis to Probiotics 413
Chapter 21
Anne-Judith Waligora-Dupriet and Marie-José Butel
Natural Products
Chapter 22
and Dermatological Hypersensitivity Diseases 435
Clayton MacDonald and Marianna Kulka
Preventive Phytotherapy
Chapter 23
of Anaphylaxis and Allergic Reactions 461
Elaine A. Cruz, Michelle F. Muzitano,
Sonia S. Costa and Bartira Rossi-Bergmann
Cissampelos sympodialis (Menispermaceae): A Novel
Chapter 24
Phytotherapic Weapon Against Allergic Diseases? 477
M.R. Piuvezam, C.R. Bezerra-Santos,
P.T. Bozza, C. Bandeira-Melo, G. Vieira and H.F. Costa
Derived Products of Helminth in the Treatment of
Chapter 25
Inflammation, Allergic Reactions and Anaphylaxis 499
C.A. Araujo and M.F. Macedo-Soares
Parasite-Derived Proteins Inhibit
Chapter 26
Allergic Specific Th2 Response 531
Hak Sun Yu
Pharmaceutical Treatment of Asthma
Chapter 27
Symptoms in Elite Athletes – Doping or Therapy 545
Jimmi Elers and Vibeke Backer
Preface
The clinical and basic science of allergic disease is moving and evolving so rapidly that
it is nearly impossible to keep up full of information regarding the news mechanisms,
signalling cell markers, cellular plasticity and expression, biological mediators targets
or molecular and genetic discovers aspects related to the allergy. Moreover the
systemic impact of this pathology determines the complexity of the more recent
evidence demonstrates that the rapid regulation of central immune organs in clinical
response of the mucosa to the allergen or offending agent. The enormous diversity
clinical, etiologic, pathogenic, diagnose and therapy is not possible to develop in a
sustainable way in this book all forms of allergic diseases present in the clinic.
Therefore, this book tried to incorporate into its own matrix the crucial issues that are
recent contributions to learning less frequent topics, with very promising therapy
approaches. So the aim and the project was at the final the scope of the title “Allergic
diseases - highlights in the clinic, mechanisms and treatment”, since it would not be
possible to materialize a project that seeks to be a formal Medical Treaty covering the
full breadth and complexity of allergy. Nevertheless, this book provides an accurate
and current learning of many clinical issues.
The quality and scientific preciseness of the authors coming from several countries,
does much to give strength to the whole book, especially as it reflects local and
regional realities that characterize the diversity of expression allergic. In fact, the
etiology and clinical response of allergic patient is very different, depending on the
location, habits, socio-economic conditions and even the specific interests of key lines
of investigation developed that the authors have incorporated into the chapters, but
always guided by higher values of accuracy.
The basic and clinical aspects of allergic disease were described, namely concepts of
innate and adaptive immune response, systemic and localized immune-mediated
allergic disease, including recent update on pathogenesis. The clinical aspects were
also subject and comprehensive developed and described, affecting different organ
systems, particularly the anaphylaxis the main severe form of allergy.
This book will provide a valuable reference text in allergy and immunology not only
for primary care physicians which are the first interfaces for an overall higher
X Preface
prevalent pathology, but also for residents in training as well for specialists. The
chapters develop themes with enormous depth and expertise, supported by updated
references, and often illustrated with personal research of great interest to further key
points of clinical investigation. Our understanding of the inflammatory process in
allergic disease is clearly defined in many of these chapters, as is the application of
science to clinical treatment. The technologies enrolled in the genetic approach were
also described as well highlight the tools for molecular study of allergy.
Overall the allergy is a sustained process of chronic inflammation why aspects of
quality of life and the contribution and understanding of the psychological dimension,
emotional and psychiatric naturally had to be enrolled in this book.
The chapters on treatment modalities and new strategies bring the latest concepts on
the use of actual and very promising researches based on the better understanding of
the mechanism of the allergic disease. Each of these topics is as current as possible and
written by a leader in the field. Clinicians will all benefit from these reviews.
The effort and dedication of the authors in the time expended in the writing of the
different chapters is fully demonstrated by the final quality of this project. To them
goes my greatest of gratitude.
I am particularly indebted to Drs Graça Loureiro, Beatriz Tavares, Daniel Machado
and Prof A Segorbe Luís, from Immunoallergy Departement of Coimbra University
Hospital Center who willingly assisted me in the review and in the scientific
discussion of some fundamental aspects that have benefited the final version. The
preparation of this edition for publication depends heavily on the excellent
professional secretarial work of Ms Molly Kaliman, Publishing Process Manager. Of
course a special thanks to the Intech-Open Access Publisher who had honored me with
that feat challenge. I am exceedingly grateful to my family and all those who are close
to me for successfully enduring this ordeal yet again.
In my humble opinion, “Allergic diseases - highlights in the clinic, mechanisms and
treatment” represents a shining example of a productive international collaboration
among colleagues, and the information inserted in this book should conduct to an
improved health care for patients with allergic diseases which are the essence of our
work.
Celso Pereira, PhD, MD
Immunoallergology
Coimbra University Hospital Center, Coimbra
Portugal
. ALLERGIC DISEASES –
HIGHLIGHTS IN THE CLINIC,
MECHANISMS AND
TREATMENT
Edited by Celso Pereira
Allergic Diseases – Highlights. patterns in the sample
Allergic Diseases – Highlights in the Clinic, Mechanisms and Treatment
8
being analyzed. In the most common approach, the colours
Ngày đăng: 23/03/2014, 17:20
Xem thêm: Allergic Diseases – Highlights in the Clinic, Mechanisms and Treatment Edited by Celso Pereira docx