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Genetic approaches to study liver development in zebrafish   core component sec13 in COPII complex is essential for liver development in zebrafish

Genetic approaches to study liver development in zebrafish core component sec13 in COPII complex is essential for liver development in zebrafish

Cao đẳng - Đại học

... synthesizes large quantities of cholesterol and phospholipids, which are either packaged with lipoproteins and transport to the rest of the body, or excreted in bile as cholesterol or bile acids after ... arthrogryposis-renal dysfunction-cholestasis (ARC) syndrome, which is the result of a mutation in another class C vps gene The tumor suppressor gene nf2 mutant develops extrahepatic choledochal cysts in ... to CLSD crusher mutants appear normal until the onset of craniofacial chondrogenesis Mechanism study revealed that crusher chondrocytes accumulate proteins in a bloated ER, resulting in severe...
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Expression analysis of GFAP like gene in zebrafish embryogenesis

Expression analysis of GFAP like gene in zebrafish embryogenesis

Tổng hợp

... overnight Embryos younger than 15 hpf were fixed before dechorionation and the chorion was removed afterwards Embryos older than 16 hpf were dechorionated before fixation After fixation, the embryos ... organizing centre of the ventral neural tube is the axial mesoderm, which is composed of the notochord and prechordal plate mesoderm The second organizing 25 centre is the floor plate, and is established ... notochord, showing the presence of zfgfap-l positive cells in the posterior neural tube dc-diencephalon; e-eye; fb-forebrain; mb-midbrain; hb-hindbrain; mhb-midbrainhindbrain boundary; n- notochord;...
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Báo cáo khoa học: Differential expression pattern of the novel serine⁄threonine kinase, STK33, in mice and men doc

Báo cáo khoa học: Differential expression pattern of the novel serine⁄threonine kinase, STK33, in mice and men doc

Báo cáo khoa học

... cells (gc), inner plexiform layer (ipl), inner nuclear layer (inl), outer nuclear layer (onl), choroid (ch) and sclera (sc) Dark staining in the pigmented epithelium (pe) was also observable ... described for yeast [42] On the other hand, STK33 orthologs are present in the genomes of several chordate organisms (Fig 7), but not found in yeast, fly or nematode genomes This is not too surprising ... et al STK33 expression pattern Fig Amino acid sequence alignment of Stk33 kinase domain in some chordates Proteins sequences from human (Hsa) and mouse (Mmu) as described in [1] Sequences from...
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báo cáo khoa học:

báo cáo khoa học: "Analysis of the expression pattern of the BCL11B gene and its relatives in patients with T-cell acute lymphoblastic leukemia" doc

Báo cáo khoa học

... effects with the BCL11B gene by decreasing mitochondrial cytochrome c release inhibitory action of the Wnt target gene osteopontin (SPP1) on mitochondrial cytochrome c release determines renal ... of T-ALL Recent evidence has suggested that multiple mechanisms may regulate the release of mitochondrial factors, some of which depend on the action of caspases BCL2L1 may inactivate caspase-8 ... formation in the plasma membrane, nucleus, and Golgi complex while diverting DISC formation to the mitochondria The inhibitory effects of BCL2L1 on DISC formation may play a significant role in protecting...
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Báo cáo khoa học: In vivo studies of altered expression patterns of p53 and proliferative control genes in chronic vitamin A deficiency and hypervitaminosis pot

Báo cáo khoa học: In vivo studies of altered expression patterns of p53 and proliferative control genes in chronic vitamin A deficiency and hypervitaminosis pot

Báo cáo khoa học

... Tris/HCl pH 8.0, 150 mM NaCl, 0.5% deoxycholate, 0.1% SDS, 1% NP-40, mM EDTA), once with high salt buffer (50 mM Tris HCl pH 8.0, 500 mM NaCl, 0.1% SDS, 0.5% deoxycholate, 1% NP-40, mM EDTA) once with ... Altered processing of precursor transcripts and increased levels of the subunit I of mitochondrial cytochorme c oxidase in syrian hamster fetal cells initiated with ionizing radiation Carcinogenesis ... cDNA synthesis was performed with lL of DNase-treated total RNA (0.1 lgÆlL)1), lL of oligo(dT) anchored primer (2 lM) 12 and lL dNTP mix (250 lM) (1 : : : 1) (v/v/v/v) using SuperScriptTM RNase...
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Báo cáo khoa học: High and complementary expression patterns of alcohol and aldehyde dehydrogenases in the gastrointestinal tract Implications for Parkinson’s disease docx

Báo cáo khoa học: High and complementary expression patterns of alcohol and aldehyde dehydrogenases in the gastrointestinal tract Implications for Parkinson’s disease docx

Báo cáo khoa học

... of SN compared to ventral tegmental area [40] Mitochondrial dysfunction is another event implicated in PD pathogenesis and inhibition of mitochondrial complex I and III leads to elevated levels ... RalDH-I and the mouse homolog was formerly known as AHD2 There are two other classes of ALDHs, mitochondrial ALDH2 and stomach cytosolic ALDH3, neither of which has been found to participate in RA ... Neurobiol Dis 14, 637–647 Grimm J, Mueller A, Hefti F & Rosenthal A (2004) Molecular basis for catecholaminergic neuron diversity Proc Natl Acad Sci USA 101, 13891–13896 Mandel S, Grunblatt E, Riederer...
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Expression pattern of matrix metalloproteinases in human gynecological cancer cell lines ppt

Expression pattern of matrix metalloproteinases in human gynecological cancer cell lines ppt

Sức khỏe phụ nữ

... Placenta Chorioncarcinoma Primary tumor Produce hCG, HCS, progesterone [36,37] JAR Placenta Chorioncarcinoma Primary tumor Produce estrogen, progesterone, hCG, HCS [38] BeWo Placenta Chorioncarcinoma ... for RT-PCR analysis: endometrium carcinoma (Endo-CA), cervical carcinoma (Cervix-CA), chorion carcinoma (Chorio-CA), ovarian carcinoma (OV-CA) and teratocarcinoma (Terato-CA) Primers, specific ... in comparison to the abovementioned cell lines, BeWo cells could be the best choice for future experiments concerning chorioncarcinoma cell lines and the Ishikawa cell line concerning endometrial...
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Báo cáo khoa học: Molecular identification and expression study of differentially regulated genes in the Pacific oyster Crassostrea gigas in response to pesticide exposure doc

Báo cáo khoa học: Molecular identification and expression study of differentially regulated genes in the Pacific oyster Crassostrea gigas in response to pesticide exposure doc

Báo cáo khoa học

... of myelin-like structures in Cyprinus carpio hepatocytes, swelling of mitochondria and disappearance of the internal mitochondrial membrane in carp at both exposure concentrations [17] However, ... pesticide dimethoate on cardiac and acetylcholinesterase activity in the shore crab, Carcinus maenas Aquat Toxicol 40, 23–26 69 Fulton MH & Key PB (2001) Acetylcholinesterase inhibition in estuarine ... Bocquene G, Roig A & Fournier D (1997) Cholinesterases from the common oyster (Crassostrea gigas) FEBS Lett 14, 1–6 ´ 71 Bocquene G & Galgani F (1998) Cholinesterase inhibition by organophosphorous...
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Báo cáo sinh học:

Báo cáo sinh học: "High ERCC1 expression predicts cisplatin-based chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area" pdf

Hóa học - Dầu khí

... has yet to be defined; the concomitant administration of cisplatin represents a widely accepted choice It has been reported that induction chemotherapy (IC) with cisplatin and fluorouracil (PF) ... staining intensity to obtain a final semi-quantitative H score The median value of the H score was chosen as the cutoff point for separating low and high levels of ERCC1 expression [22] survival ... JL, De Raucourt D, Rhein B, Wibault P, Marandas P, Coche-Dequeant B, Stromboni-Luboinski M, Sancho-Garnier H, Luboinski B: Randomized trial of neoadjuvant chemotherapy in oropharyngeal carcinoma...
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báo cáo hóa học:

báo cáo hóa học:" High ERCC1 expression predicts cisplatin-based chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area" pdf

Hóa học - Dầu khí

... has yet to be defined; the concomitant administration of cisplatin represents a widely accepted choice It has been reported that induction chemotherapy (IC) with cisplatin and fluorouracil (PF) ... staining intensity to obtain a final semi-quantitative H score The median value of the H score was chosen as the cutoff point for separating low and high levels of ERCC1 expression [22] survival ... JL, De Raucourt D, Rhein B, Wibault P, Marandas P, Coche-Dequeant B, Stromboni-Luboinski M, Sancho-Garnier H, Luboinski B: Randomized trial of neoadjuvant chemotherapy in oropharyngeal carcinoma...
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Báo cáo khoa học:

Báo cáo khoa học: " Linkage disequilibrium pattern of the ATM gene in breast cancer patients and controls; association of SNPs and haplotypes to radio-sensitivity and post-lumpectomy local recurrence" doc

Báo cáo khoa học

... Sedgwick RP: Ataxia-telangiectasia (Clinical and immunological aspects) Psychiatr Neurol Med Psychol Beih 1970, 13-14:8-16.:8-16 Olsen JH, Hahnemann JM, Borresen-Dale AL, Tretli S, Kleinerman ... Correlates With The Number of Risk Alleles Int J Radiat Oncol Biol Phys 2007, 68:229-235 Lee KM, Choi JY, Park SK, Chung HW, Ahn B, Yoo KY, Han W, Noh DY, Ahn SH, Kim H, Wei Q, Kang D: Genetic...
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Báo cáo y học:

Báo cáo y học: " Differential binding and co-binding pattern of FOXA1 and FOXA3 and their relation to H3K4me3 in HepG2 cells revealed by ChIP-seq" docx

Báo cáo khoa học

... starting material Here, three fragment sizes were also chosen for the immunoprecipitation material, but only the 250- to 300-bp fragment size was chosen from the input The in-gel PCR was performed ... enzymes (GGT¥) Yuan et al *LDL, low density lipoproteins †ALT, alanine-aminotransferase ‡TC, total cholestrol §HDL, high density lipoproteins TG, triglycerides ¥GGT, gamma-glutamyl transferase for ... nuclei were resuspended in RIPA-buffer (1× phosphate-buffered saline (PBS), 1% NP-40, 0.5% Na-deoxycholate, 0.1% SDS, 0.004% Na-azide) for sonication with a Bioruptor (Diagenode, Liège, Belgium)...
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báo cáo khoa học:

báo cáo khoa học: " Isolation, identification and expression analysis of salt-induced genes in Suaeda maritima, a natural halophyte, using PCR-based suppression subtractive hybridization" doc

Báo cáo khoa học

... synthesis of choline occurs following the route phospho-ethanolamine (P-EA) to phospho-choline, P-choline (bold arrows, Fig 2) However, the route P-EA to phosphatidylcholine, Ptd-choline (normal ... phosphoethanolamine to phosphocholine, which is either dephosphorylated to form choline directly [92] or first incorporated into phosphatidylcholine and then metabolized to choline [93] (Fig 2) Primarily ... choline metabolites upon supply of 14C-choline demonstrated that choline import into chloroplast indeed limited its flux to glycinebetaine [99] Hence, it was postulated that a high-activity choline...
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Báo cáo y học:

Báo cáo y học: "Effects of ischemic pre- and postconditioning on HIF-1a, VEGF and TGF-b expression after warm ischemia and reperfusion in the rat liver" ppsx

Báo cáo khoa học

... preconditioning protects post-ischemic oxidative damage to mitochondria in rat liver Shock 2005, 24:370-375 15 Sun K, Liu ZS, Sun Q: Role of mitochondria in cell apoptosis during hepatic ischemia-reperfusion ... assessed by liver parameters, and we speculate that the explanation may be the same as above We choose the Knudsen et al Comparative Hepatology 2011, 10:3 http://www.comparative-hepatology.com/content/10/1/3 ... ischaemia exceeding h Br J Surg 1993, 80:1161-1165 10 Belghiti J, Noun R, Malafosse R, Jagot P, Sauvanet A, Pierangeli F, Marty J, Farges O: Continuous versus intermittent portal triad clamping...
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Báo cáo sinh học:

Báo cáo sinh học: "Cloning, chromosome mapping and expression pattern of porcine PLIN and M6PRBP1 genes" pdf

Báo cáo khoa học

... dropletassociated proteins of adipocytes, Proc Natl Acad Sci 90 (1993) 12035– 12039 [6] Ellegren H., Chowdhary B.P., Johansson M., Andersson L., Integrating the porcine physical and genetic linkage ... Hawken R.J., Murtaugh J., Flickinger G.H., Yerle M., Robic A., Milan D., Gellin J., Beattie C.W., Schook L.B., Alexander L.J., A first-generation porcine whole-genome radiation hybrid map, Mamm Genome ... Cabau C., Leroux S., Genet C., Lahbib Y., Tosser G., Robic A., Hatey F., Alexander L., Beattie C., Schook L., Yerle M., Gellin J., 226 [18] [19] [20] [21] [22] [23] [24] [25] [26] [27] [28] X Tao...
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Application of bayesian model selection in fluorescence correlation spectroscopy (FCS) to WNT3EGFP secretion and diffusion in zebrafish embryos

Application of bayesian model selection in fluorescence correlation spectroscopy (FCS) to WNT3EGFP secretion and diffusion in zebrafish embryos

Thạc sĩ - Cao học

... fluorescent proteins and their brightness in CHO cytoplasm 74 Figure 4.10 Model probabilities and model selection of fluorescent proteins in CHO cytoplasm at different excitation intensities ... different fitting models using EGFP measured in CHO cytoplasm 76 Figure 4.12 Model probabilities and model selection and of fluorescent proteins in CHO cytoplasm with different acquisition ... selection at 37 ° 78 C Figure 4.14 PMT-EGFP in CHO cells and its model probabilities 80 Figure 4.15 Inferred fitting parameters of PMT-EGFP on CHO membrane with different excitation intensities...
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