ca2 causes facilitation of transmitter release
Tài liệu Báo cáo khoa học: Synchronization of Ca2+ oscillations: involvement of ATP release in astrocytes pdf
... apyrase [5,7] Third, visualization of the release of ATP demonstrates that the velocity of ATP release correlates well with that of the Ca2+ wave in astrocytes [5] All of these findings suggest that ... to evoke Ca2+ transients in the cell (b) If neurons are excessively excited, perisynaptic astrocytes causes frequent Ca2+ transients or Ca2+ oscillations, followed by the spreading of Ca2+ transients ... results in the formation of Ins(1,4,5)P3, leading to Ca2+ release from Ca2+ stores (B) Multiple pathways for the release of ATP Hemichannels of connexin or pannexin, maxi-anion channels, P2X7 receptors...
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Báo cáo khoa học: ATP-binding domain of heat shock protein 70 is essential for its effects on the inhibition of the release of the second mitochondria-derived activator of caspase and apoptosis in C2C12 cells potx
... role of HSP70 in the inhibition of the release of Smac and apoptosis GAPDH Ratio of HSP70 to GAPDH 14 # 12 # 10 * The role of the ATP-binding domain of HSP70 in the prevention of the release of ... over-expression of both mutant HSP70DPDB and full-length HSP70WT similarly inhibited the release of Smac from mitochondria, but mutant HSP70DATP-BD lost its ability to inhibit the release of Smac These ... prevention of the release of Smac from mitochondria Similarly, over-expression of HSP70DPDB behaved similarly to full-length HSP70 (HSP70WT) in other functional assays, including the inhibition of the...
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Báo cáo khoa học: Functional significance of five noncanonical Ca2+-binding sites of human transglutaminase 2 characterized by site-directed mutagenesis potx
... 2009 FEBS 7091 Ca2+ -binding sites of TG2 ´ly R Kira et al Fig Multiple sequence alignment of Ca2+ -binding sites of transglutaminases Sequence alignments of Ca2+ -binding sites of TG2 compared ... contributions Ca2+ binding of mutant TG2 proteins To compare the Ca2+ binding of wild-type and mutant enzymes in equilibrium dialysis, a free Ca2+ concentration of 1.7 mm was used In case of the WT, ... binding of celiac autoantibodies to TG2 is influenced by the presence or absence of Ca2+ in the case of guinea pig TG2 [27] Therefore, we also examined the effect of Ca2+ and GDP on the binding of...
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Báo cáo khoa học: Frataxin deficiency causes upregulation of mitochondrial Lon and ClpP proteases and severe loss of mitochondrial Fe–S proteins pot
... expression of any of the mitochondria-encoded genes tested at and weeks of age in the hearts of MCK mutants as compared with control littermate mice (Table 1) In contrast, at a late stage, five genes of ... decreasing its rate of turnover We also addressed the fate of several mitochondrial Fe–S proteins in cardiac tissue of MCK mutants, and showed an overall clearance in protein levels of key mitochondrial ... Results Modulation of Lon and ClpP expression in cardiac muscles of MCK mutants Using the MCK mutants, we investigated the effect of frataxin deficiency on the possible regulation of the two mitochondrial...
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Báo cáo khoa học: Irregular dimerization of guanylate cyclase-activating protein 1 mutants causes loss of target activation ppt
... in the absence of Ca2+ However, staining intensity of the large fragment b was lower in the absence of Ca2+ indicating that progessive trypsin digestion of the Ca2+ -free form of CaM–GCAP-1 had ... binding of Ca2+ smaller and the majority of CPG–GCAP-1 eluted as a protein of apparent molecular mass of 45 kDa and is similar to the behaviour of the CaM–GCAP-1 mutant in the presence of EGTA ... approximately two Ca2+ (1.8 ± 0.3) at saturating free [Ca2+ ] and not as expected three bound Ca2+ However, denaturing Chelex treated wild-type GCAP-1 led to the additional release of 1.2 ± 0.75 Ca2+ per...
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Báo cáo hóa học: " Research Article Efficient Compensation of Transmitter and Receiver IQ Imbalance in OFDM Systems" pptx
... compensation of transmitter and receiver IQ imbalance from the compensation of channel distortion The proposed schemes require the presence of frequency selective channel fading for the estimation of IQ ... for transmitter IQ imbalance Figure 4: BER versus SNR for OFDM system (a) D-FEQ based transmitter IQ imbalance compensation for a 16QAM OFDM system Frequency independent amplitude imbalance of ... obtained by taking the average of the BER curves over 104 independent channels Figure 4(a) considers the presence of only transmitter IQ imbalance in a 16QAM OFDM system The transmitter filter impulse...
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Báo cáo hóa học: " Research Article Analysis and Compensation of Transmitter and Receiver I/Q Imbalances in Space-Time Coded Multiantenna OFDM Systems" ppt
... estimation error figure of merits with transmitter and receiver I/Q imbalances and received SNR of 20 dB, as a function of subcarrier index k in a × 256-subcarrier STC-OFDM system; extended vehicular ... data modulation and the number of OFDM subcarriers is N = 256, with subcarrier spacing of 120 kHz The powerdelay profiles of the individual radio channels between the transmitters and the receiver(s) ... rejection of state of the art RF-IC 40 39 Attenuation (dB) 38 37 36 35 34 33 32 31 30 −8 −7 −6 −5 −4 −3 −2 −1 Frequency (MHz) Figure 1: Measured mirror-frequency attenuation of state -of- theart...
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báo cáo khoa học: " Over-expression of miR172 causes loss of spikelet determinacy and floral organ abnormalities in rice (Oryza sativa)" pps
... analysis of accumulation of miR172 in wild-type RNA gel blot analysis of accumulation of miR172 in wild-type plants A, Accumulation of miR172 in vegetative tissues 2L-S and 2L-R: shoot and root of ... result of repression of SNB and at least one of the other four target genes, most likely Os03g60430, by the elevated levels of miR172 in plants over-expressing miR172b Our analyses of expression of ... each PCR, μl of 1:40 diluted template cDNA was mixed with μl of 10 × PCR buffer, 0.7 μl of 50 mM MgCl2, 0.4 μl of mM dNTPs, 0.4 μl each of 10 mM forward and reverse primers, 0.5 μl of 1:10000 diluted...
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Báo cáo y học: "A targeted lipidomics approach to the study of eicosanoid release in synovial joints" pdf
... (baseline, no treatment administered yet), hours of placebo, hours of NSAID, 24 hours of placebo, 24 hours of NSAID, 168 hours of placebo, and 168 hours of NSAID The x- and y-axes denote discriminant ... those of commercially available standards of the compound of interest Only peaks with the correct combination of m/z transition and RT were considered to be positively identified as the analyte of ... screening of SF samples by using an IS for estimation of extraction efficiency and requires only 300 μL of SF to analyze a much wider spectrum of eicosanoids, thus enabling the detection of mediators...
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Báo cáo khoa học: "Fatality after deliberate ingestion of sustained-release ibuprofen: a case report" pdf
... This is the first reported case of fatality following ingestion of sustainedrelease ibuprofen and the first fatality following isolated ibuprofen toxicity Ibuprofen is a NSAID commonly used as ... presumed sustained -release case would support the use of multidose activated charcoal in the management of patients who have ingested a sustainedrelease preparation of ibuprofen in any subsequent ... that symptoms of ibuprofen toxicity following ingestion of a standard release preparation usually occur within four hours of ingestion [4,5] Severe toxicity is uncommon following ibuprofen self-poisoning,...
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Báo cáo y học: "Identification of signaling components required for the prediction of cytokine release in RAW 264.7 macrophages" pdf
... estimate of the amount of cytokine released Results Signaling pathways and cytokine release after ligand stimulation The AfCS provides a global profiling of signaling responses and cytokine release ... allows the elucidation of the common and different signaling modules required for the release of different cytokines, and the quantitative prediction of amounts of cytokines released The Alliance ... cytokine releases Indeed, significant positive correlations were observed between activation of any of ERK1/2, GSK3A, GSK3B, JNKs, p38, NFκB, PKCµ2, RSK or Rps6 and any of the cytokine releases...
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industrial ecology approach to management of fly ash from fluidized bed combustion production of slow-release fertilizer and soil conditioner
... Potassium content of the pellets • Leaching test of the pellets (to ascertain the rate of potassium release, and the presence of trace elements in the leachate) • Mechanical strength of the pellets ... influence of introduced CaCO3 was shown by an increment of pH and 30 of the concentration of Ca and HCO3 in the soil’s leachate in the first week of liming Other liming effects included increase of ... that causes a decrease in pH by means of the acid displacement of cations of the interchanging complex towards the solution The interchangeable aluminum reduction in the low part of the profile...
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facilitation of protein three-dimensional structure determination using enhanced peptide amide deuterium exchange mass spectrometry (dxms)
... Software QTOF Data Analyzed with QTOF Data Analyzed with DXMS Reduction Software DXMS Reduction Software LCQ Data Analyzed with LCQ Data Analyzed with DXMS Reduction Software DXMS Reduction Software ... of data analysis using deuterium exchange data reduction software allows correct identification of peptides (Fig 3C), thus ensuring that the pool of peptides used for structural analyses is of ... example of validation studies of HR-DXMS de-convolution HR-DXMS deconvolution of Cytochrome-c 224 Figure 6-3: high-density fragmentation DXMS data on a 221 aa two-tandem- repeat construct of...
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Convention on facilitation of international maritime traffic 1965 (FAL 1965)
... State of ship Last port of call/Next port of call Number of persons on board 10 Quantity Place of storage 11 Official use Convention on Facilitation of International Maritime Traffic Name of article ... type of ship 1.2 IMO number 1.3 Call sign Port where report is made Flag State of ship Name of master Port of loading/Port of discharge Marks and Nos Number and kind of packages; description of ... the cargo • number of crew • number of passengers • brief particulars of voyage • date and time of arrival, or date of departure • port of arrival or departure • position of the ship in the port...
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Mechanism of arsenic release to groundwater, Bangladesh and West Bengal
... for irrigation wells outside of town sites Tungipara, in the district of Gopalganj, is 100 km SW of Dhaka (inset) The area within the dotted line marks the border of the Madhupur Tract new tubewells ... oxidation of Asbearing pyrite, with a concomitant release of As to groundwater (Das et al., 1995, 1996; Roy Chowdhury et al., 1998) Such a mechanism is incompatible with the redox chemistry of the ... De, 1995) The nature of ¯uvial deposits, however, makes dicult the de®nition of laterally continuous or contiguous sedimentary layers The evolution of the most recent parts of the sedimentary...
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Detailed kinetic mechanism of gasphase reactions of volatiles released from biomass pyrolysis
... Kinetics of devolatilization of reference species in the solid/ metaplastic phase; Kinetics of the gas-solid gasification and combustion of residual char; Secondary gas-phase reactions of gas ... range of experimental conditions Recently, experimental data showed the overshooting of temperature at the center of thick biomass particles, and allowed a better evaluation of the endothermic release ... parameters of abstraction of secondary Hatoms in alkanes (Fig 2) Similarly, the abstraction parameters of a H-atoms, such those of iso-propanol and 2-butanol, are ~1.5 times the corresponding ones of...
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Báo cáo hóa học: " Involvement of intracellular free Ca2+ in enhanced release of herpes simplex virus by hydrogen peroxide" ppt
... Results are representative of independent experiments Effect of buffering [Ca2+ ]i on H2O2-mediated enhancement of viral release The effect of Ca2+ depletion on the release of HSV-1 was examined Eighteen ... buffering of [Ca2+ ]i by Ca2+ chelators diminished the effect of H2O2 on the release of HSV-1, we concluded that the enhanced viral release following H2O2 treatment was ascribed to a Ca2+ -mediated ... (% of control) B 500 Virus titer (% of control) A 60 40 * * 60 40 20 20 100 ** ** 100 0 H2O2 (mM) BAPTA quin-2 EGTA BAPTA quin-2 Figureof Ca2+ depletion Effects on viral release Effects of Ca2+ ...
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Báo cáo y học: "Does switching from oral extended-release methylphenidate to the methylphenidate transdermal system affect health-related quality-of-life and medication satisfaction for children with attention-deficit/hyperactivity disorder&
... dose of drug delivered depends on the surface area of the patch and the length of time that the patch is worn, which allows for tailoring the duration of medication effect with reductions of first-pass ... satisfied with the efficacy of the study medication on their child's attention The majority of caregivers (93.1%) indicated a high level of satisfaction with the duration of effect of the study medication ... dose of oral ERMPH, the AIM-C child HRQL mean (SD) score was 62.4 (20.5) At end of study, the child HRQL mean (SD) score increased to 73.4 (18.4), reflective of a 17.5% increase after weeks of...
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Release of anti-cyanobacterial allelochemicals from aquatic and terrestrial plants applicable for artificial floating islands
... Hishikaki, Japan) Confirmation of the release of anti-cyanobacterial allelochemicals In order to confirm the release of anti-cyanobacterial allelochemicals, the culture solution of each plant was subjected ... 500 Figure Comparison of fragment pattern of the peak E (a) at 13.508 with that of vanillic acid-TMS ester (b) and fragment pattern of the peak F (c) at 14.513 with that of protocatechuic acid-TMS ... demonstrated the growth inhibition of M aeruginosa, thereby confirming the release of anti-cyanobacterial compounds from these plants GC/MS analyses of the solid extract of C alternifolius culture solution...
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Effect of Coagulant on Phosphorus Uptake and Release in EBPR Process
... stabilization of phosphorus removal efficiency was investigated The objective of this study is to clarify the effect of coagulant on phosphorus uptake and release as well as the stabilization of phosphorus ... Summary of Experimental Results The mean and standard deviation of MLSS, SRT, effluent SS, D-BOD and T-N are shown in Table By the removal of the activated sludge as the excess sludge, MLSS of each ... and release during the anaerobic and aerobic phases Therefore, three key points of phosphorus behavior namely, the initial phosphorus release rate (vrel), phosphorus concentration at the end of...
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Tìm thêm: xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến tốc độ rôto n fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25