alpha beta and their receptor

Báo cáo sinh học: " Synergistic inhibition of human cytomegalovirus replication by interferon-alpha/beta and interferon-gamma" pot

... NK cells and activated T-cells in response to virus-infected cells [25] Both types of IFNs achieve their antiviral effects by binding to their respective receptors (IFN-α/β or IFN-γ receptors), ... Effect of IFN-α, IFN-β and/ or IFN-γ on HCMV plaque formation Treatment Vehicle IFN-α IFN-α IFN-β IFN-β IFN-γ IFN-γ IFN-α and IFN-β IFN-α and IFN-γ IFN-β and IFN-γ IFN-α, IFN-β and IFN-γ IU/mla Log ... activates inflammatory cytokine responses via CD14 and Toll-like receptor J Virol 2003, 77:4588-4596 Sainz B Jr, Halford WP: Alpha/ Beta interferon and gamma interferon synergize to inhibit the replication...

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báo cáo hóa học:" Synergistic inhibition of human cytomegalovirus replication by interferon-alpha/beta and interferon-gamma" docx

Danh mục: Hóa học - Dầu khí

... NK cells and activated T-cells in response to virus-infected cells [25] Both types of IFNs achieve their antiviral effects by binding to their respective receptors (IFN-α/β or IFN-γ receptors), ... Effect of IFN-α, IFN-β and/ or IFN-γ on HCMV plaque formation Treatment Vehicle IFN-α IFN-α IFN-β IFN-β IFN-γ IFN-γ IFN-α and IFN-β IFN-α and IFN-γ IFN-β and IFN-γ IFN-α, IFN-β and IFN-γ IU/mla Log ... activates inflammatory cytokine responses via CD14 and Toll-like receptor J Virol 2003, 77:4588-4596 Sainz B Jr, Halford WP: Alpha/ Beta interferon and gamma interferon synergize to inhibit the replication...

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Báo cáo khoa học: "Real time PCR analyses of expression of E-cadherin, alpha-, beta- and gamma-catenin in human breast cancer for predicting clinical outcome" pps

Danh mục: Báo cáo khoa học

... IO: An immunohistochemical examination of the expression of E-cadherin, alpha- and beta/ gamma-catenins, and alpha2 - and beta1 -integrins in invasive breast cancer J Pathol 1999, 187:523-529 Dillon ... breast cancer Br J Cancer 2001, 85:1958-1963 Bukholm IK, Nesland JM, Karesen R, Jacobsen U, Borresen-Dale AL: E-cadherin and alpha- , beta- , and gamma-catenin protein expression in relation to metastasis ... invasion and degradation of surrounding matrix, and migration into the vasculature and surrounding tissue, E-cadherin catenin complex is reintroduced and cells adhere to the vasculature and form...

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Cytoskeleton reorganization mediates alpha beta integrin-associated actions of laminin on proliferation and survival, but not on steroidogenesis of ovine granulosa cells pdf

Danh mục: Sức khỏe phụ nữ

... pg/well) and the intra- and inter-assay coefficients of variation were less than 7% and 9% respectively The progesterone detection limit was 12 pg/tube (60 pg/ well), and the intra- and inter-assay ... conceived the study, participated in its design and coordination, statistical analysis and interpretation of data and drafted the manuscript FLB, SF and DM read and approved the final manuscript CP died ... JP: Analysis of the roles of RGD-binding integrins, alpha( 4) /alpha( 9) integrins, alpha( 6) integrins, and CD9 in the interaction of the fertilin beta (ADAM2) disintegrin domain with the mouse egg...

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Báo cáo khoa học: Arthropod nuclear receptors and their role in molting pptx

Danh mục: Báo cáo khoa học

... recognized by other receptors For example, vertebrate steroid hormone receptors (such as GRs, mineralcorticoid receptors, progesterone receptors and androgen Arthropod nuclear receptors receptors) bind ... create the hydrophobic ligand-binding pocket Several differences are evident when comparing unliganded and ligand-bound receptors [16] Ligand binding to the receptor (holo -receptor) occurs through ... (NRs) and cofactors, and then summarize the study of arthropod ecdysteroid receptors, including sequences, functions, ligand-binding characteristics and the application of ligand receptor complexes...

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báo cáo hóa học:" RAGE (Receptor for Advanced Glycation Endproducts), RAGE Ligands, and their role in Cancer and Inflammation" pptx

Danh mục: Hóa học - Dầu khí

... an extracellular "decoy receptor" , antagonizing flRAGE and other receptors by binding DAMPs and other ligands and inhibiting leukocyte recruitment in a variety of acute and chronic inflammatory ... protein families that readily form aggregates and oliogmers – Amyloid beta peptide, Collagen, and AGEs RAGE and Abeta The Amyloid -beta peptide (Abeta) is a peptide most commonly of 40 or 42 amino ... Conclusion RAGE and its ligands play essential roles in inflammation, neurobiology, cancer, and numerous other conditions Each ligand distinctly activates RAGE and contributes to the innate and adaptive...

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báo cáo hóa học:" Identification of a public CDR3 motif and a biased utilization of T-cell receptor V beta and J beta chains in HLA-A2/Melan-A-specific T-cell clonotypes of melanoma patients" potx

Danh mục: Hóa học - Dầu khí

... T-cell receptor (TR) plays a central role in the immune response, interacting with peptide antigens (Ags) and with major histocompatibility complex (MHC) molecules TR alpha (TRA) and beta subunits ... contributions FS, and AS have made substantial contribution in the acquisition and alignment of sequences, in the analysis and interpretation of data, and helped to draft the manuscript LC, BP, PGN, and PN, ... Bodmer HC, McMichael AJ, Bell JI: Extensive conservation of alpha and beta chains of the human T-cell antigen receptor recognizing HLA-A2 and influenza A matrix peptide Proc Natl Acad Sci USA 1991,...

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Báo cáo y học: "Genetic analysis of HIV-1 Circulating Recombinant Form 02_AG, B and C subtype-specific envelope sequences from Northern India and their predicted co-receptor usage" pot

Danh mục: Báo cáo khoa học

... envelope sequence comparison and coreceptor usage HIV-1 envelope sequence comparison and coreceptor usage HIV-1 envelope gene was amplified from infected individuals and subjected to sequencing ... regions are shown with their accession numbers, their subtype assignment and possible co -receptor usage Dots in the sequence indicate identity with consensus C, B, 02_AG and A sequences; asterisk ... envelope showed exclusive use of CCR5 co -receptor [11] It is important to note that Samples A82 and C5 showed discrepancy in their predicted coreceptor usage and this is because the two programs...

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Báo cáo khoa hoc:" Expression of estrogen and progesterone receptors in vestibular schwannomas and their clinical significance" docx

Danh mục: Báo cáo khoa học

... obtained and the standard streptavidin biotin peroxidase immunohistochemical method was used for the expression of estrogen and progesterone receptors Estrogen receptor (Clone 1D5, Dako, USA) and ... the most common cerebellopontine angle tumor and represents 9% of all brain tumors (Figure 1) Expression of estrogen and progesterone receptors and their potential role in the progression of vestibular ... cerebellopontine angle tumor and it expresses various hormone receptors for examples estrogen, progesterone, androgen, somatostatin and glucocorticoid The clinical significance of these receptors is that...

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Báo cáo y học: " Bench-to-bedside review: Toll-like receptors and their role in septic shock" pps

Danh mục: Báo cáo khoa học

... humans these include not only the receptor and accessory protein for IL-1, but also the IL-18 receptor and its accessory protein, and the long-sought signaling receptor for LPS, TLR4 [1,8] The ... and the type interleukin-1 receptor (IL-1R1) complex AcP, accessory protein; Ig, immunoglobulin; MyD88, myeloid differentiation factor; R, receptor; TIR, Toll/IL-1 receptor (IL-1R1) This expanding ... Postreceptor signaling of the IL-1R is well understood Binding of the ligand causes receptor dimerization and, with involvement of IL-1RAP (an accessory protein), the intracellular part of the receptor...

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Báo cáo y học: "The mouse “xenotropic” gammaretroviruses and their XPR1 receptor" pps

Danh mục: Báo cáo khoa học

... structure is not representative of all retroviral receptors, some of which, like the lentivirus CD4 receptor and the receptors for alpha- and betaretroviruses have single TM domains [99] Although ... silenced, and the Env glycoproteins of infectious recombinant P-MLVs have narrow receptor requirements and reduced receptor binding efficiency, these multiple mechanisms ensure their transmission and ... mice, MLVs can and cause disease in their natural hosts, and the induction of disease can involve X-MLVs and P-MLVs as well as E-MLVs Mouse strains carrying active Emvs, like AKR, HRS, and C58, have...

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Báo cáo y học: "Impact of IL8 and IL8-Receptor alpha polymorphisms on the genetics of bronchial asthma and severe RSV infections" doc

Danh mục: Báo cáo khoa học

... has been described with asthma [8] and RSV bronchiolitis [9,10] IL8 binds with high affinity to two different receptors: IL8 receptor alpha (IL8RA, CXCR1) and beta (IL8RB, CXCR2) These closely ... described with asthma and chronic obstructive pulmonary disease [13] We were interested in the relationship between severe RSV infection and/ or bronchial asthma and IL8 and IL8RA polymorphisms ... polymorphisms (-251A/T and 781C/T) and three amino acid variants in IL8RA (M31R, S276T and R335C), which are located in the N-terminus of the protein, in the third extracellular loop and in the Cterminus...

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Báo cáo y học: "Expression of aromatase and estrogen receptor alpha in chondrosarcoma, but no beneficial effect of inhibiting estrogen signaling both in vitro and in vivo" ppt

Danh mục: Báo cáo khoa học

... JJ012) and primary chondrosarcoma cell cultures (L869 and L835), and a positive control (ZR-75-1) were trypsinized and washed twice with cold PBS Cells were formalin-fixed over night and subsequently ... enzyme responsible for the conversion of androstenedione and androgens to estrogens, was expressed in 86% (38 out of 44) and 93% (25 out of 27) of the central and peripheral chondrosarcomas respectively ... aromatase inhibitors (anastrozole, letrozole, and exemestane), and two estrogen -receptor antagonists/downregulators (4-hydroxytamoxifen and fulvestrant) and again no effect was shown in the Discussion...

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Báo cáo y học: "The chemokine and chemokine receptor superfamilies and their molecular evolution" pot

Danh mục: Báo cáo khoa học

... usually bind to multiple receptors and vice versa (the complex and promiscuous ligand -receptor relationships; Figure 1); and second, cluster chemokines Classification, clustering and gene duplication ... that chemokines and their receptors first arose as molecules controlling the transit of various cells within organisms simpler than mammals, and suggests that chemokines and their receptors have ... superfamily, arranged by the receptors they bind to Chemokines are represented by only their ligand number, and the receptor name also indicates whether each ligand is a CC or CXC; for example,...

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Study of GDNF family receptor alpha 2 and inhibitory activity of GDNF family receptor alpha 2b (GFR alpha 2b) isoform

Danh mục: Cao đẳng - Đại học

... neurotrophic factors GDNF and NTN exert their effects through a multi-component receptor system consisting of the GDNF family receptor alpha (GFRα) and the co -receptor RET and/ or NCAM GDNF preferentially ... family of ligands (GDNF family of ligands, GFLs) Chapter Literatures review and receptors (GDNF family of receptors alpha, GFRα) in neuronal and non-neuronal systems 2.2 GDNF family of ligands (GFLs) ... ligands (GFLs) 2.3 GDNF family receptors _ 2.4 Alternatively spliced isoforms of GFRs and their co-receptors 14 2.5 GFRα2 and GFRα1 receptor...

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Synthesis of crown ether and cyclam capped beta cyclodextrin bonded silica particles and their application as chiral stationary phases in liquid chromatography

Danh mục: Cao đẳng - Đại học

... RESULTS AND DISCUSSION Selective modification of the primary and secondary hydroxyl groups of β-CD is complicated and very difficult to control because of statistical and steric problems D′Souza and ... isomers of disubstituted benzenes and stereoisomers of chiral compounds under both normal phase and reversed-phase conditions in HPLC and UHPLC The enantioselectivity and column efficiency for columns ... Ettre and K.I Sakodynskii, Chromatographia, 35 (1993) 329 (5) E Katz, R Eksteen, P Schoenmakers and N Miller, Handbook of HPLC, Marcel Dekker Inc., New York, 1998, ch (6) A.J.P Martin and R.L.M...

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Cloning of medaka glial cell derived neurotrophic factor (GDNF) and its receptor GFR alpha 1

Danh mục: Tổng hợp

... tyrosine kinase is mediated by GDNFR -alpha, a novel receptor for GDNF Cell 85, 1113-24 Jing S, Yu Y, et al (1997) GFRalpha-2 and GFRalpha-3 are two new receptors for ligands of the GDNF family J Biol ... Fig GDNF-family ligand interaction with their receptors All GFLs activate RET tyrosine kinase via different GFRα receptors Solid arrows indicate the preferred functional ligand -receptor interactions, ... H, Hoffer B, Olson L (1997) Neurturin and glial cell line-derived neurotrophic factor receptor -beta (GDNFR -beta) , novel proteins related to GDNF and GDNFR -alpha with specific cellular patterns...

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Attackers and Their Attacks

Danh mục: Kỹ thuật lập trình

... disinformation and propaganda – Deny service to legitimate computer users – Commit unauthorized intrusions into systems and networks that result in critical infrastructure outages and corruption ... malicious intent • Use their skills to expose security flaws Crackers • Person who violates system security with malicious intent • Have advanced knowledge of computers and networks and the skills to ... employees, and cyberterrorists • Password guessing is a basic attack that attempts to learn a user’s password by a variety of means • Cryptography uses an algorithm and keys to encrypt and decrypt...

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Báo cáo y học: " Predictors of hepatic steatosis in HBeAg-negative chronic hepatitis B patients and their diagnostic values in hepatic fibrosis"

Danh mục: Y học thưởng thức

... evaluate the predictors of clinical and pathological characteristics in these patients with steatosis and their diagnostic values in hepatic fibrosis Patients and methods Patients A total of 204 ... steatosis (83 men and 23 women, mean age: 41.08±10.23 years) and the remaining 98 patients were excluded from hepatic steatosis (79 men and 19 women, mean age 39.4±9.81 years) Their diagnoses were ... activity), and G3 (severe activity) All the sections were blindly and independently assessed by pathologists and the results were processed by the Kappa concordance test The inter- and intra-observer...

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LEAN MANUFACTURING PRINCIPLES AND THEIR APPLICATION 2008

Danh mục: Tài liệu khác

...

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