Investigation of the role of microRNAs in spinocerebellar ataxia type 3
Investigation of the role of microRNAs in spinocerebellar ataxia type 3
... 19 -33 Ataxia type (SCA1) Spinocerebellar Ataxia type (SCA2) Spinocerebellar Ataxia type (SCA3) Spinocerebellar Ataxia type (SCA6) calcium channel subunit Spinocerebellar ATXN7 Ataxin 4 -35 37 -30 6 ... interspersed by introns that are omitted in the ATXN3 mRNA (b) The initial exons code for the Josephin domain in the ATXN3 protein, the rest of the exons code for the C-terminal domain with the ... TATA-binding 25-44 47- 63 Ataxia type (SCA7) Spinocerebellar Ataxia type 17 protein (SCA17) Huntington’s Disease HTT Huntingtin 6 -35 36 -121 AR Androgen receptor 10 -36 38 -62 ATN1 Atrophin 7- 23 47-55...
- 139
- 507
- 0
an investigation into the role of chemokines in haemopoietic stem cell quiescence
... 1 AN INVESTIGATION INTO THE ROLE OF CHEMOKINES IN HAEMOPOIETIC STEM CELL QUIESCENCE Amy Sinclair BSc (hons), MRes Submitted in fulfilment of the requirements for the degree of Doctor of Philosophy ... heavily involved in the production and regulation of all cell types in the biological system, including in haemopoiesis The identification of stem cells marked an important discovery in the field of ... field of biology and medicine The haemopoietic system represents an important component in the stem cell time line, beginning with a variety of observations including the acceptance of donor bone...
- 309
- 522
- 0
The role of microRNAs in embryonic stem cell development and differentiation
... as in embryonic carcinoma (EC) cells, which may have conserved roles in mammalian pluripotent stem cells (2) microRNAs expressed specifically in ESCs but not in other cells including EC cells These ... putative minimal promoter The number and precise sequences of the pre -microRNAs, their distance from the promoter and the polyadenylation sites, the regions flanking the hairpins, and the types, ... THE ROLE OF MICRORNAS IN EMBRYONIC STEM CELL DEVELOPMENT AND DIFFERENTIATION TAY MEI SIAN YVONNE B.Sc (Hons), NUS A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY NUS...
- 192
- 377
- 0
Investigation into the role of interactive learning, aimed at increasing k40 studentsenglish speaking ability in hanoi pedagogical university n0 2
... nevertheless popular and effective tools to improve students‟ English speaking ability ii STATEMENT OF AUTHORSHIP Title: INVESTIGATION INTO THE ROLE OF INTERACTIVE LEARNING, AIMED AT INCREASING K40 ... ROLE OF INTERACTIVE LEARNING, AIMED AT INCREASING K40 STUDENTS‟ ENGLISH SPEAKING ABILITY IN HANOI PEDAGOGICAL UNIVERSITY NUMBER 2 II Spoken English ability II.1 The importance of speaking English ... focuses on investigating the role of interactive learning among K40 students at Hanoi Pedagogical University Number (HPU2) The study therefore begins by giving a theoretical background of interactive...
- 51
- 381
- 0
báo cáo hóa học:" Emerging role of microRNAs in diagnosis and treatment of various diseases including ovarian cancer" pdf
... deletion or loss -of- function mutations in the survival of motor neuron (SMN) protein results in SMA [12] Gemin and Gemin are shared components of SMN and miRNAcontaining ribonucleoprotein particles ... overexpression of miR-375 resulted in suppressed glucose-stimulated insulin secretion and its inhibition resulted in enhanced insulin secretion Myotrophin, a protein that has a role in exocytosis, ... up-regulated and were down-regulated It was determined that increased expression of miR-181a, miR-181b, and miR-213 in OVCA cell lines results in resistance to doxorubicin and gemcitabine and increased...
- 9
- 440
- 0
báo cáo khoa học: "Characterization of the stress associated microRNAs in Glycine max by deep sequencing" pot
... 15.69% in the alkalinity induced library The relatively lower percentage of 24 nt reads indicates that more kinds of miRNAs are involved in the response of G max to alkalinity compared with other stress ... complete profile of miRNAs in Glycine max Keyword: deep sequencing, Glycine max, microRNAs, stresses associated, miRNA Background Terrestrial plants face serious abiotic stresses (e.g drought, salinity, ... Characterization of the stress associated microRNAs in Glycine max by deep sequencing Haiyan Li1, 2, §, Yuanyuan Dong1, §, Hailong Yin2, Nan Wang1, Jing Yang1, Xiuming Liu1, 2, Yanfang Wang1, 2, Jinyu Wu1,...
- 32
- 280
- 0
Báo cáo y học: "cGlobal analysis of microRNA target gene expression reveals the potential roles of microRNAs in maintaining tissue identity" ppsx
... Global analysis of microRNA target gene expression reveals the potential roles of microRNAs in maintaining tissue identity Zhenbao Yu* , Zhaofeng Jian, Shi-Hsiang Shen, Enrico Purisima, and Edwin ... its targets for their expression Theoretically, the tissues with low level of the expression of the targets of a miRNA are probably the tissues in which the miRNA is functionally involved Systematical ... targets These findings strongly suggest that miRNAs play a most important role in driving tissue terminal differentiation and particularly in maintaining tissue identity rather than in determining...
- 47
- 313
- 0
Investigation of demotivators in English speaking lessons of the 10th grade students at Nam Sach High School = Nghiên cứu các yếu tố gây nên sự mất hứng thú tro
... communicativeness - General evaluation - The teaching of listening skills - The teaching of speaking skills - The teaching of reading skills - The teaching of writing skills - The teaching of grammar ... Table 4.2) The lowest mean was 2.51, indicating that half of the students were not satisfied with the design of the textbook Indeed, 50% were not attracted by the design of the textbook The highest ... mean of 2.5 Indeed, out of teachers disagreed that the design of the textbook was attractive The organizational structure of the textbook, in contrast, got a high mean of 4.13, indicating a high...
- 61
- 865
- 0
FACTORS AFFECTING JOB PERFORMANCE AN INVESTIGATION OF EMPLOYEES IN THE VIETNAMESE BANKING INDUSTRY
... Unfortunately, the demand of banking employees is forecasted to be in the down –trend in the next few years According to the point of view of specialists in banking industry, many banks will cut off the employees ... services of banks (See more information about Vietnamese Banking Industry in Appendix A) Among many industries, banking industry is one of the most industry has the fastest growth in the human resources ... improve key factors in order to enhance the job performance In point of view of employees in Vietnamese banking industry, both the factors of psychology capital and quality of working life are...
- 69
- 575
- 0
Tài liệu Báo cáo khoa học: "An Empirical Investigation of Discounting in Cross-Domain Language Models" ppt
... of occurrences in the test data for trigrams that appeared 10 times in training data Discounting by a single value is plausible in the case of similar train and test corpora, where the mean of ... this second point in constructing our language model, an advantage of our approach over subsampling is that we use our entire training corpus, and in so doing compromise between minimizing errors ... Modeling Computer Speech & Language, 15(4):403– 434 Bo-June (Paul) Hsu and James Glass 2008 Ngram Weighting: Reducing Training Data Mismatch in Cross-Domain Language Model Estimation In Proceedings...
- 6
- 444
- 0
Tài liệu Báo cáo khoa học: "An Empirical Investigation of Proposals in Collaborative Dialogues" docx
... the intervening dialogue renders the solution size determinate In out of the indeterminate antecedent AD+Os, our hypothesis is verified (see excerpt (1), where [35] is an AD+ with indeterminate ... exist to the set of constraint equations, each varl in the set of equations must have a solution For example, if instances of sofas are known for varsola, but every assignment of a value to varsoIa ... considers joint actions as decomposable into in- dependent Influence-on-Speaker / Hearer dimensions 4Space constraints prevent discussion of segments and it is 1) past; or 2) non past, and contains...
- 5
- 452
- 0
Báo cáo khoa học: A study of microRNAs in silico and in vivo: diagnostic and therapeutic applications in cancer pot
... et al (2005) A microRNA polycistron as a potential human oncogene Nature 435, 828–833 39 Hayashita Y, Osada H, Tatematsu Y, Yamada H, Yanagisawa K, Tomida S, Yatabe Y, Kawahara K, Sekido Y & Takahashi ... this approach discriminates normal and neoplastic tissues in various cancer types, including CLL, breast cancer, glioblastoma, thyroid papillary carcinoma, hepatocellular carcinoma, lung cancer, ... minireview was to provide, in overview, a summary of the potential application of miRNAs as diagnostic and therapeutic targets in cancer TranslaƟonal repression Fig miRNA generation and gene regulation...
- 8
- 432
- 0
Báo cáo khoa học: A study of microRNAs in silico and in vivo: bioimaging of microRNA biogenesis and regulation doc
... stages and the changes of these networks in disease and after application of a variety of therapeutic strategies Critically, 2172 the noninvasive imaging approach of miRNA generation and its activity ... monitoring the therapeutic potential of miRNAs in cancer Bioimaging of microRNA biogenesis The molecular mechanisms involved in miRNA generation are complex, and at least several processing steps in ... measuring the decrease of optical signal in vivo [34] Also, miRNA21 is a potential therapeutic 2170 target for cancer treatment, as overexpression of antimiRNA21 in hepatocellular carcinoma and...
- 10
- 463
- 0
Báo cáo hóa học: " Investigation of cracks in GaN films grown by combined hydride and metal organic vaporphase epitaxial method" ppt
... doi:10.1186/1556-276X-6-69 Cite this article as: Liu et al.: Investigation of cracks in GaN films grown by combined hydride and metal organic vapor-phase epitaxial method Nanoscale Research Letters 2011 ... stresses during metalorganic chemical vapor deposition of GaN on sapphire Appl Phys Lett 2005, 86:261907 Hoffman RW: In situ observation of coalescence-related tensile stresses during metalorganic ... Akasaki I: Relaxtion Process of the thermal Strain in the GaN/ α-Al2O3 Heterostructure and Determination of the Insrinsic Lattice Constants of GaN Free from the strain Jpn J Appl Phys 1992, 31:L.1454...
- 8
- 295
- 0
investigation of effectiveness in pair group work in teaching English
... classroom in FFL CHAPTER II: LITERATURE REVIEW/THEORITICAL FRAMEWORK 2.1 Definitions of Pair work and Group work Pair work -group work has been incorporated into language teaching and learning in most ... benefits of having students work in pairs or groups? Shown in Table Q13 In your opinion, what are the obstacles in the implementation of pair work and group work in your speaking classes? Shown in ... am doing research on Pair work -Group work in teaching speaking for the first year students of FFL - IUH” This questionnaire aims to investigate the implementation of pair work and group work...
- 43
- 859
- 4
Từ khóa: the emerging role of micrornas in adult stem cellsthe role of micrornas in the management of liver cancerthe discovery of the involvement of micrornas in human cancerjr camargo ca anwaruddin s et al 2005 the n terminal probnp investigation of dysnea in the emergency department pride study am j cardiol 95 948 954translational implications of micrornas in clinical diagnostics and therapeuticsdiagnosis biopsy and investigation of pathology in childrenfive decades of investigation of somitogenesis in xenopus laevisthe role music plays in filmthe role music plays in our lifethe role music plays in my lifevariations on a theme of paganini in a minor op 35a role for micrornas in therapy resistanceadherence metabolic control and quality of life in adolescents with type 1 diabetes the idea is found in oda s emily bronte and the gothic female characters in wuthering heights page 3spinocerebellar ataxia type 10 a disease caused by a large attct repeat expansionBáo cáo quy trình mua hàng CT CP Công Nghệ NPVNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhPhát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngNghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngĐịnh tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Thơ nôm tứ tuyệt trào phúng hồ xuân hươngChuong 2 nhận dạng rui roBT Tieng anh 6 UNIT 2chuong 1 tong quan quan tri rui roGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vật