translational implications of micrornas in clinical diagnostics and therapeutics
Báo cáo y học: "Sustained remission of rheumatoid arthritis with a specific serotonin reuptake inhibitor antidepressant: a case report and review of the literature" ppsx
Ngày tải lên :
11/08/2014, 00:23
... and preparation of the manuscript RTK was involved in collating information regarding the case and getting informed consent from the patient JC was involved in review of literature and revising ... improvement in joint pain, skin pain, or itching, suggesting that the improvement in mood was independent of improvement in psoriasis Serotonergic systems modulate inflammation Descending serotonergic ... decrease in 5-HT2A binding potential, suggesting a decrease in receptor density over a period of six weeks They found that this decrease in binding potential became less pronounced with increasing...
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formation of zno thinfilms consisting of nano-prisms and nano-rods with a high
Ngày tải lên :
06/05/2014, 13:23
... recombination between electrons in the conduction band and holes in the valence band and visible emission is related to the defects in the ZnO [20] The UV emission of ZnO thin films grown in the ... concentration and show a high intensity of deep-level emission results from defect-related emission in the thin film indicating the deterioration of characteristics In addition, the small grain size and ... Zn(NO3)$6H2O and mM of Al(NO3)$6H2O dissolved in 80 ml of DI water Solution D was formulated with 0.03 M of Zn (NO3)$6H2O, mM of Al(NO3)$6H2O and mM of Na3C6H5O7 dissolved in 80 ml of DI water...
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Báo cáo hóa học: "Reference values and physiological characterization of a specific isolated pig kidney perfusion model" doc
Ngày tải lên :
20/06/2014, 00:20
... transformed into logarithmic scaling and linear lines instead of curves are resulting for constant values of the creatinine clearance In that way figure was constructed and the interrelation of the ... the exception of creatinine Creatinine was added to the perfusate for the purpose of determination of the exogenous creatinine clearance, resulting in 3–4 fold concentration levels in comparison ... declining lines in the nomogram Using this approach, two hypergroups or clusters of kidneys were found (figure 1): The first cluster containing groups CON and A arrange in a falling linear band...
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Báo cáo khoa học: "Commissioning and early experience with a new-generation low-energy linear accelerator with advanced delivery and imaging functionalities" doc
Ngày tải lên :
09/08/2014, 09:21
... recently introduced in the clinical arena (at the moment with the exclusion of USA, Canada and Japan) by Varian Medical Systems The results of the commissioning tests and of the first period of clinical ... settings and during clinical usage was included Results: Isocenter virtual diameter was measured as less than 0.2mm Observed accuracy of isocenter determination and repositioning for 2D-2D matching ... Index (fraction of points passing the gamma criteria) of 97.0±1.6% on the first 182 arcs verified Conclusions: The results of the commissioning tests and of the first period of clinical operation,...
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Báo cáo y học: "gA retroperitoneal abscess caused by Haemophilus parainfluenza after endoscopic retrograde cholangiopancreatography and open cholecystectomy with a common bile duct exploration: a case report" ppt
Ngày tải lên :
11/08/2014, 12:20
... obtaining images ZH carried out the search and obtained data on H parainfluenza, and cross referenced its occurrence to extra-respiratory infections, assisted in compiling the manuscript, and ... occur in less than 1% of patients [5] The majority of these abscesses are colonized by gastrointestinal tract flora [5] H parainfluenza is a normal inhabitant of the human respiratory tract and ... route of translocation into the gastrointestinal tract is largely unknown We postulate that, in this case, the H parainfluenza found in the retroperitoneal abscess originated from the oropharynx and...
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Báo cáo y học: " A gastrointestinal stromal tumour presenting incidentally with haemorrhage and perforation associated with a Meckel’s diverticulum: a case report" pps
Ngày tải lên :
11/08/2014, 17:21
... range of presenting features, including abdominal pain, an abdominal mass, gastrointestinal bleeding, small bowel obstruction, weight loss, fever, abscess or perforation [7] Competing interests ... (11.4%) and leiomyoma (9.4%) with overall malignancy in 77% of cases [7] The definition of a gastrointestinal stromal tumour (GIST) has varied since the first use of the term in 1983 Originally, ... GIST accounts for 0.1% and 3% of all gastrointestinal neoplasms, most commonly occurring in the stomach or small bowel, and is now the most common sarcoma of the small intestine [10] Small bowel...
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Báo cáo y học: "Dialectical Behavioral Therapy for Adolescents (DBT-A): a clinical Trial for Patients with suicidal and self-injurious Behavior and Borderline Symptoms with a one-year Follow-up" pot
Ngày tải lên :
13/08/2014, 18:21
... treatment, that includes concurrent individual therapy once a week, family therapy as needed and a multifamily skills training group in an outpatient setting An open clinical trial by Rathus and Miller ... were defined as follows: Inclusion criteria - Age at the beginning of therapy between 13 and 19 years - Non-suicidal self-injurious and/ or suicidal behavior in the past 16 weeks - Diagnosis of BPD ... DBT-A, nor in the year following therapy All adolescents had shown non-suicidal self-injurious behavior and cutting of the skin of the forearms (mainly superficial) prior to therapy In the month...
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Báo cáo y học: "Blunt traumatic pericardial rupture and cardiac herniation with a penetrating twist: two case reports" ppt
Ngày tải lên :
13/08/2014, 23:21
... includingthe heart demonstrating most of the axial findings Coronal3chest CT into the right hemithorax and displaceCoronal chest CT demonstrating most of the axial findings including the prominent ... requiring high dose norepinephrine and epinephrine to sustain his mean arterial pressure He was re-trauma called at this stage and plain radiographs were obtained to further ascertain and clarify ... may report symptoms of palpitations, shortness of breath and chest pain as well as angina type pains as a result of coronary obstruction following herniation [2,11] The main clinical signs, which...
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money and trade considered, with a proposal for supplying the nation with money
Ngày tải lên :
05/11/2014, 09:13
... notwithstanding the difference of Interest If Money in Scotland were equal to the Demands at per cent, the Dutch could not trade so cheap in Herring; The Hinderances of that Trade being the Consequences ... the Trouble, Hazard, and Expense, to himself of offending Money out, to the other of bringing Money home, and to both the Expense of Re-coyining So long as Forreign Trade, and Expense kept equal, ... London And the 400000 lib of English Goods in Holland, are only worth 360000 lib that Sum being equal by Exchange to 400000 lib in England So in place of Englands having an Advantage of 40000...
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The herpetofauna of the peruvian dry forest along the andean valley of the marañón river and its tributaries, with a focus on endemic iguanians, geckos and tegus
Ngày tải lên :
19/11/2015, 15:51
... Fingers lacking expanded terminal discs; finger I longer than finger II …….……7 Fingers with expanded terminal discs………… ………………………………… Dorsolateral folds and longitudinal ridges present and distinct………………………………… ... Lemairocereus), and by terrestrial and aboreal bromeliads (e.g., Pitcairnia, Tillandsia) (Duellman & Pramuk 1999, Hughes et al 2004) Principle sources of income of the majority of people inhabiting the investigation ... compilation of map; writing and proof reading 18 BIODIVERSITY OF THE PERUVIAN DRY FOREST HERPETOFAUNA Abstract A checklist of the amphibians and reptiles of 22 localities situated in the northern...
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Báo cáo khoa học: Structural and biological effects of a b2- or b3-amino acid insertion in a peptide Application to molecular recognition of substance P by the neurokinin-1 receptor ppt
Ngày tải lên :
08/03/2014, 08:20
... and w and were subsequently refined by varying /, w angles in intervals of 10° and setting h angle to ) 60 ± 10° and 60 ± 10° Each /, h, and w-value was fixed by applying a harmonic potential and ... within the specific NK-1m binding site The CH2b of the pyrrolidine ring of [Pro9]SP probably fits within this hydrophobic subsite and thus compensates destabilizing interactions due to CH2c and ... cause steric hindrance and does not confine orientations of the side chain to regions of space different from those permitted in the a-amino acid Thus, insertion of a single b-amino acid in a bioactive...
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Báo cáo Y học: Selection of effective antisense oligodeoxynucleotides with a green fluorescent protein-based assay Discovery of selective and potent inhibitors of glutathione S-transferase Mu expression doc
Ngày tải lên :
31/03/2014, 15:20
... EGFPcontaining proteins were visualized with enhanced chemiluminescence The positions and molecular weights of the marker proteins are indicated in the left margin In the right margin, the estimated ... confirmed the in- frame ligation of the GSTM cDNAs and the absence of any PCR-induced mistakes in the inserts TRITC-labelling of ODN A 24-mer PO-ODN, provided with three PS-linkages at the 5¢-end and a ... biomarkers in in vitro and in animal models As GSTM knock-out mice are still unavailable, temporal modulation of the expression of GSTM isoforms by AS-ODNs in relevant in vitro and in vivo models...
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Báo cáo hóa học: " Comparison of three rapamycin dosing schedules in A/J Tsc2+/- mice and improved survival with angiogenesis inhibitor or asparaginase treatment in mice with subcutaneous tuberous sclerosis related tumors" docx
Ngày tải lên :
18/06/2014, 16:20
... agent vincristine, combination vincristine plus rapamycin, single agent sunitinib, combination sunitinib plus rapamycin, single agent bevacizumab, and combination bevacizumab plus rapamycin As ... is favored, and mTOR kinase is constitutively activated causing hyperphosphorylation of the downstream effectors (p70 S6 kinase and 4E-binding protein1) resulting in increased protein translation, ... rapamycin treated, asparaginase treated, asparaginase plus rapamycin combination treated, vincristine treated, vincristine plus rapamycin combination treated, sunitinib treated, sunitinib plus...
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Báo cáo sinh học: "Gene therapy with tumor-specific promoter mediated suicide gene plus IL-12 gene enhanced tumor inhibition and prolonged host survival in a murine model of Lewis lung carcinoma" pptx
Ngày tải lên :
18/06/2014, 19:20
... Bank of the Chinese Academy of Science (Shanghai, China) and maintained in 5% CO2 at 37°C in Dulbecco’s minimum essential medium (DMEM) containing 10% fetal bovine serum (FBS), 100 U/ml penicillin ... by measuring cell viability, and in vivo, by determining the tumor size and animal survival, assessing both tumoral histology and infiltration of Page of 10 T-lymphocytes, and evaluating toxic ... proliferation and cytotoxic activity of T cells and NK cells and initiating Th1-type immune responses by activation of CD4+ and CD8+ cells [16] In the present study, we investigated a combined target...
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báo cáo hóa học: " The possible link between the elevated serum levels of neurokinin A and anti-ribosomal P protein antibodies in children with autism" pot
Ngày tải lên :
19/06/2014, 22:20
... within the brain Tachykinins may have a role in augmenting the immune functions of CNS glial cells resulting in the progression of damaging inflammation within the CNS [39] Brain mast cells in ... proliferation, invasion into living cells and starting apoptosis, a defect in the synthesis of apolipoprotein B resulting in accumulation of lipids inside the cell, and downregulation of the total protein ... of tachykinins and neurokinins Trends Pharmacol Sci 2000;21: 173–175 6- Almeida TA, Rojo J, Nieto PM, Pinto FM, Hernandez M, Martin JD, et al Tachykinins and tachykinin receptors: structure and...
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Báo cáo hóa học: " Nucleotide mismatches between the VP7 gene and the primer are associated with genotyping failure of a specific lineage from G1 rotavirus strains" potx
Ngày tải lên :
20/06/2014, 01:20
... years it was reported that the accumulation of point mutations in VP4 and VP7 genes was the main cause of the failure of the G or P-typing of rotavirus strains [7,8,12,16-21] At least, there are four ... [7,12,17,20,21], and In order to evaluate how many G1 strains included in the GenBank database have these four specific mismatches and its clustering within specific lineages, we collected 173 sequences of ... lineages are represented in the tree as follows: lineage I (orange), lineage II (green), lineage III (blue) and lineage IV (red) lected to understand this complex epidemiology [15] However, in...
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báo cáo hóa học:" Gene therapy with tumor-specific promoter mediated suicide gene plus IL-12 gene enhanced tumor inhibition and prolonged host survival in a murine model of Lewis lung carcinoma" doc
Ngày tải lên :
20/06/2014, 03:20
... Bank of the Chinese Academy of Science (Shanghai, China) and maintained in 5% CO2 at 37°C in Dulbecco’s minimum essential medium (DMEM) containing 10% fetal bovine serum (FBS), 100 U/ml penicillin ... by measuring cell viability, and in vivo, by determining the tumor size and animal survival, assessing both tumoral histology and infiltration of Page of 10 T-lymphocytes, and evaluating toxic ... proliferation and cytotoxic activity of T cells and NK cells and initiating Th1-type immune responses by activation of CD4+ and CD8+ cells [16] In the present study, we investigated a combined target...
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Báo cáo y học: "Validation of a specific measure to assess healthrelated quality of life in patients with schizophrenia and bipolar disorder: the ‘Tolerability and quality of life’ (TOOL) questionnaire" doc
Ngày tải lên :
09/08/2014, 01:21
... afford greater insight in describing and grading the impact of side effects associated to antipsychotic drugs [15,16] A brief instrument is preferred for use in clinical practice and in investigations ... males (n = 151) Sociodemographic and clinical characteristics of the sample are shown in Tables and The percentage of missing values in each of the items contained in the questionnaire was less ... UK: National Institute of Mental Health in England; 2005 Thornicroft G, Tansella M: Growing recognition of the importance of service user involvement in mental health service planning and evaluation...
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