... Arthritis Research & Therapy Vol No Ogawara et al as stress response, innate and adaptive immune reactions, and apoptosis [5-8] In endothelial cells, NF-κB is activated by inflammatory cytokines, ... To achieve selective gene transfer of dnIκB into endothelial cells, adenovirus can be used as a vector Infection by adenovirus is initiated by the high affinity binding of the carboxy-terminal ... [25] Among them, IL-6 and IL-8 are mainly produced by endothelial cells and are critical players in the initiation phases of immunity and inflammation Besides its active role in inflammation,...