CHARACTERISATION OF GLUTAMYL TRANSPEPTIDASE AND ELUCIDATING ITS ROLES IN THE PATHOGENESIS OF HELICOBACTER PYLORI
CHARACTERISATION OF GLUTAMYL TRANSPEPTIDASE AND ELUCIDATING ITS ROLES IN THE PATHOGENESIS OF HELICOBACTER PYLORI
... recombinant proteins in E coli Raising and characterizing specific polyclonal and monoclonal antibodies against GGT Determining the subcellular localization of GGT in H pylori Investigating the ... Assessing the ability of GGT in inducing IL-8 generation in various cell types Analyzing GGT entry into host cells and its probable downstream effects Examining the role of GGT in vacuolation induction ... ability to maintain long-term colonization in the gastric mucosa of the mice compared to the wild type strain, indicating the importance of catalase in the chronic persistence of H pylori (Harris...
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Báo cáo y học: "Bench-to-bedside review: Functional relationships between coagulation and the innate immune response and their respective roles in the pathogenesis of sepsis" ppsx
... carboxyl terminus of peptides and proteins In the case of fibrin, removal of carboxyl-terminal lysine residues renders the fibrin less sensitive to lysis by decreasing the ability of plasminogen and ... Functional interrelationships between clotting and the innate immune response The close ancestral and functional linkage between clotting and inflammation is readily appreciated in study of human physiologic ... [7,15] Any injury to the exoskeleton of the crab immediately jeopardizes the integrity of the internal milieu of the organism Not only is there a real threat of loss of internal contents of the crab...
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Báo cáo y học: " Th2 cytokines and asthma Interleukin-4: its role in the pathogenesis of asthma, and targeting it for asthma treatment with interleukin-4 receptor antagonists" pot
... circulating cytokine, coupled with the high specificity and high affinity of binding for the cytokine, makes the soluble receptor ideal as a cytokine antagonist Soluble recombinant human IL-4 receptor ... heterodimer of high-affinity IL-4Rα and either the common γ chain or the IL-13 receptor α chain Binding of IL-4 results in the tyrosine phosphorylation of signal transduction molecules including motifs ... chains of the heterodimer are required to initiate intracellular signaling (b) The sIL-4R consists of the extracellular portion of IL-4Rα It retains the ability to bind IL-4 with high affinity and...
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Characterization of helicobacter pylori y glutamyl transpeptidase and its role in pathogenesis
... assay 57 3.5.2 Growth of different H pylori strains 57 3.5.3 Inhibitory effect of serine borate complex on H pylori GGT activity 58 3.5.4 Stimulatory effect of GSH and glycyl-glycine on H pylori ... activity of H pylori 100 4.2.2.2 GSH enhances the GGT acitivity of H pylori 101 4.2.2.3 Effects of GGT inhibitor and enhancer on the growth of H pylori 102 4.3 Sequencing of ggt gene of H pylori ... fuction of H pylori GGT thereby providing a new focus in H pylori- mediated IL-8 generation The role that membrane bound GGT plays in affecting growth of H pylori, its effect on hydrogen peroxide and...
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Characterization of candida albicans cyclase associated protein CAP1 and its roles in morphogenesis g actin associates with the adenylyl cyclase cyr1 through cap1 and regulates cAMP synthesis in candida albicans hyphal morphogenesis
... CHARACTERIZATION OF CANDIDA ALBICANS CYCLASE- ASSOCIATED PROTEIN CAP1 AND ITS ROLES IN MORPHOGENESIS — G- actin Assoicates with the Adenylyl Cyclase Cyr1 through Cap1 and Regulates cAMP Synthesis ... resulting in impaired response to the hyphal- inducing signals Furthermore, the finding that the purified Cyr1 /Cap1/ actin complex can increase cAMP synthesis in response to hyphal- inducing molecules ... activate cAMP synthesis by binding to the LRR domain of Cyr1, suggesting that Ras1 may not be essential for hyphal induction In some conditions, the G protein- coupled receptor Gpr1 and the G protein...
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Cadmium Removal by the Hydroponic Culture of Giant Reed (Arundo donax) and Its Concentration in the Plant
... effect of the cadmium addition on the appearance of the plant body was not observed during days in runs to Assimilation of cadmium in giant reed Fig shows the cadmium concentration in giant reed ... wetland is not enough to design the multi-functional wetland The purposes of this study are thus to clarify the dynamics of cadmium removal by giant reed, and investigate its concentration in plant ... gramineous plants, i.e., maize, oat, barley, and rice Thus, the dynamics of cadmium in giant reed culture seems to affect the GSH production Therefore, the production property of GSH in giant reed...
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Expansion and its realization in the short story “the law of life” by jack london
... features of the text and the intention of the writer In this thesis, the text chosen is the short story The Law of Life” by the famous American writer, Jack London Aims of the study The study ... Expansion and its realization in the short story The Law of Life by Jack London has been finished Now we shall sum up the results of the study In chapter of the study, the theoretical background of the ... 1996 The story The Law of Life” was written by Jack London and first published in Mc Clure’s Magazine in 1901 Since its appearance, the story has made big impression on the reader and has been...
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Tài liệu Báo cáo khoa học: High affinity copper binding by stefin B (cystatin B) and its role in the inhibition of amyloid fibrillation docx
... interface formed in the tetramer would disrupt copper < /b> binding < /b> Inhibition of amyloid fibril formation by < /b> stefin < /b> B in presence of copper < /b> The mechanism of amyloid fibril formation of cystatins is being studied ... histidine residues are central to copper < /b> binding < /b> in many proteins they probably form part of the copper < /b> binding < /b> sites in this protein Although there are four histidines in the C-terminal, another ... copper < /b> binding < /b> or loss of its binding < /b> could be related to specific cerebellar function(s) of stefin < /b> B [18], which remains to be seen by < /b> more in vivo studies Stefin < /b> B as a copper < /b> binding < /b> protein We...
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Tài liệu Báo cáo khoa học: Inorganic pyrophosphatase in the roundworm Ascaris and its role in the development and molting process of the larval stage parasites doc
... that the hypodermis of the body wall, which synthesizes components of the cuticle, may offer a useful target for studies into the mechanism of the development and molting process in the roundworms ... presence of increasing concentrations of inhibitors for 10 days, and the number of molting larvae was determined Molting was manifested by shedding of the L3 cuticle Results Identification of cDNA ... involved in the molting process, we examined the effects of two PPase specific inhibitors, imidodiphosphate (IDP, 1-0631; Sigma) and NaF on development and molting of A suum lungstage L3 to fourth-stage...
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Báo cáo khoa học: Identification and characterization of 1-Cys peroxiredoxin from Sulfolobus solfataricus and its involvement in the response to oxidative stress pdf
... thioredoxins were found In this study we examined the involvement of the peroxiredoxin Bcp2 in oxidative stress in the hyperthermophilic aerobic archaeon Sulfolobus solfataricus Furthermore, ... clarified in detail and could play a key role in the detoxification processes In this study we examined the role of Bcp2 in order to increase the knowledge of the enzymatic activity involved in the oxidative ... Furthermore, we report the cloning, the expression and the characterization of the recombinant protein rBcp2 in order to shed light on its role in the detoxification process and on its catalytic mechanism...
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Báo cáo khoa học: FLIP and MAPK play crucial roles in the MLN51-mediated hyperproliferation of fibroblast-like synoviocytes in the pathogenesis of rheumatoid arthritis pdf
... followed by the blocking of FLS apoptosis FLIP upregulated by MLN51 plays a crucial role in the anti-apoptosis of MH7A cells We examined whether FLIP was involved in the antiapoptosis of MH7A cells ... affect MLN51 and FLIP induction in MH7A cells (Fig 5B), indicating that ERK is unlikely to be involved in the GM-CSF-mediated induction of MLN51 and FLIP in RA FLSs These data suggest that MAPK, particularly ... 3551 FLIP and MAPK in MLN51-mediated FLS hyperproliferation J.-E Ha et al A Fig Summary diagram showing the role of MLN51 in the GM-CSF-mediated proliferation of RA FLSs via MAPK activation and induction...
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Báo cáo khoa học: Characterization of Trypanosoma brucei PEX14 and its role in the import of glycosomal matrix proteins pptx
... We interpret this observation as the retainment of newly synthesized proteins in the cytosol due to the inability to import matrix proteins by the fraction of growing and dividing glycosomes The ... lower (not shown) In order to determine the in uence of the reduction of the expression of TbPEX14 on the import of glycosomal matrix proteins, the subcellular distribution of glycolytic enzymes ... identified in yeast) PEX17 Several other peroxins are involved in the subsequent steps of the import The import of matrix proteins seems to involve a cascade of interactions between the cargo-loaded...
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Báo cáo khoa học: Roles of prolactin-releasing peptide and RFamide related peptides in the control of stress and food intake potx
... Takayanagi and T Onaka PrRP and RFRPs in metabolism and stress Table Summary of mammalian RFamide peptides and their receptors The effects of administration of RFamide peptides upon stress responses ... in the termination of meals and the induction of energy consumption Energy homeostasis and stress interact with each other Stress affects food intake and energy expenditure On the other hand, ... progress in research investigating the roles of these two peptides in the control of energy metabolism and stress PrRP PrRP was considered to serve as a hypothalamicreleasing factor and to act on the...
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Báo cáo khoa học nông nghiệp " Investigation of rice kernel cracking and its control in the field and during post-harvest processes in the Mekong Delta of Vietnam " docx
... not defined Institute Information Project Name Investigation of rice kernel cracking and its control in the field and during post-harvest processes in the Mekong Delta of Vietnam Vietnamese Institution ... provincial councils in Mekong Delta 22 shared the existing information and experiences on rice cracking The document prepared (in Vietnamese only) during the workshop will be presented in the next progress ... investigate the effect of tempering on the increase in the mechanical strength of rice This was the preliminary work mainly to establish the methodology and feasibility of the research The glass transition...
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Project Progress Report: " Investigation of rice kernel cracking and its control in the field and during post-harvest processes in the Mekong Delta of Vietnam - Ms5" pot
... Name Investigation of rice kernel cracking and its control in the field and during post-harvest processes in the Mekong Delta of Vietnam Vietnamese Institution Nong Lam University Vietnamese Project ... training courses, based on the outcome of the survey and experiments The above activities can be clustered into groups: - The 8-ton dryer - The 1-ton dryer - Survey, training, and extension The ... more rice cracking during milling This explains why dryers installed since 2003 have been more and more of the reversible principle - Air reversal also decreased the drying time - The drying temperature...
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Từ khóa: compare and contrast the roles of for profit and non profit organizations in the economychromium roles in the regulation of lean body mass and body weightoverview of the finding concurrency design space and its place in the pattern languageoverview of the algorithm structure design space and its place in the pattern languageoverview of the supporting structures design space and its place in the pattern languageadjuvant online review of evidence concerning its validity and other considerations relating to its use in the nhsamp 151 a new experimental method and its application in the photodissociation of small aromatic molecules cheng liang huang yuan t lee and chi kung nis disease and do the initial results of its ef •cacy implicate al in the pathogenesis of the diseasequot bystander effect quot and its role in the breakdown of self tolerance a positive regulator of the onset of autoimmunitya comparative analysis on the motion verbs and their lexicalization patterns in the chapter the battle of hogwarts and its vietnamese versionwater distribution and its balance in the bodyorganisational structures and job roles in the interactive media industryphilosophy and organization theory research in the sociology of organizationshow many different species of animals and plants are there in the amazon rainforestrates market rates and retail bank rates in the euro area in the context of the recent crisisBáo cáo quy trình mua hàng CT CP Công Nghệ NPVchuyên đề điện xoay chiều theo dạngNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Nghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngTìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinThơ nôm tứ tuyệt trào phúng hồ xuân hươngThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíKiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtĐổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namMÔN TRUYỀN THÔNG MARKETING TÍCH HỢPTÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ