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Báo cáo y học: "A novel approach to measure the contribution of matrix metalloproteinase in the overall net proteolytic activity present in synovial fluids of patients with arthritis" pptx

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Báo cáo y học: " A Practical Approach to Managing Patients with HCV Infection"

... international normalized ratio (INR), and a liver panel. Although the serum aminotransferase level correlates poorly with liver histology, the ratio of aspartate aminotransferase (AST) to alanine ... duration and dosage, as well as the response rate depend on HCV genotype, HCV load and other factors. The pegylated interferon is an interferon that has a polyethylene glycol moiety attached, ... decompensation, development of HCC, and mortality. In addition, HCV infection has been linked to a variety of extra-hepatic manifestations such as autoimmune diseases, lymphoma, monoclonal gammopathies...
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Báo cáo y học: "A Practical Approach to Management of Chronic Hepatitis B"

... bbiiooggrraapphh y y Ke-Qin Hu, MD, is the Director of Hepatology Services and Associate Professor of Clinical Medicine, Divisions of Gastroenterology and Transplantation, University of California, ... different stages of chronic hepatitis B infection. Hepatology 2002; 36:1408-1415. 20. Yang LM, Xu KC, Zhao YL, Wu ZR, Chen TF, Qin ZY,et al. Clinical significance of liver biopsy in chronic hepatitis ... sensitive to LAM treatment [16]. 4. Indications of HBV Treatment Historically, levels of HBV DNA and ALT, and histological activity of liver biopsy have been used as the three main factors to determine...
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Báo cáo khoa học: "A Novel Approach to Semantic Indexing Based on Concept" ppt

... weightingã Term reweighting based on conceptã Semantic index term extractionThe former two components are based on conceptextraction using lexical chains, and the latter two com-ponents are related ... as a concept vector inconcept vector space, and the overall text vector wasmade up of those concept vectors. The semantic im-portance of concepts and words was normalized ac-cording to the ... capturing the semantic importance of in a document, and to represent the lexical cohesionstructure of a document(Morris, 1991).3 Semantic Indexing Based on ConceptCurrent approaches to index weighting...
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Báo cáo y học: "A novel approach to measure the contribution of matrix metalloproteinase in the overall net proteolytic activity present in synovial fluids of patients with arthritis" pptx

... stoichiometric binding of protease inhibitors to the catalytic site of the activated forms of the enzymes. In the present work, we have measured by flow cytometry the net proteolytic activity ... 1 Proteolytic activity in synovial fluid of patients with osteoarthritis and inflammatory arthropathiesProteolytic activity in synovial fluid of patients with osteoarthritis and inflammatory ... secreted in SF by infiltrating inflam-matory cells and/or by stromal cells stimulated by inflammatorycytokines [21,22]. To assess whether inflammation does cor-relate with the proteolytic activity...
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Báo cáo y học: "A new approach to understanding the impact of circadian disruption on human health'''' pps

... employed to estimate the functional input to the human circadian system, which appears to apply to bothlight-induced nocturnal melatonin suppression andphase shifting [23].Examination of Figure ... CentralPage 1 of 14(page number not for citation purposes)Journal of Circadian RhythmsOpen AccessResearchA new approach to understanding the impact of circadian disruption on human healthMark ... humans the period of the master clock isslightly longer than 24 hours [1]. To maintain synchronywith the external world, the light-dark pattern incident on the retina resets the timing of the...
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Báo cáo y học: "A novel method to identify and characterise peptide mimotopes of heat shock protein 70-associated antigens" pptx

... purposes)Journal of Immune Based Therapies and VaccinesOpen AccessOriginal researchA novel method to identify and characterise peptide mimotopes of heat shock protein 70-associated antigensBlanca ... developed a novel method to identify syntheticmimic peptides of Hsp70-PCs and to test their ability to activate T-cells. Peptides (referred to as"recognisers") that bind to Hsp70-PCs ... displaylibrary to a non-tumourigenic Hsp70-PC fraction to enrich for true tumour-specific recogniser peptides and/ orthe use of tandem mass spectroscopy to directly sequence and identify the peptides...
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Báo cáo y học: "A novel approach to sonographic examination in a patient with a calf muscle tear: a case report" docx

... report a case of a middle-aged man with tennisleg. Ultrasound examination had normal findings during the first two attempts. During the thirdattempt, with the patient s calf muscles examined in an ... revealednegative sonographic findings. However, he still complained of persistent pain in his left calf area. A different ultrasound examination approach was then performed with the patient lying in the supineposition ... bony fractures.The patient returned to the clinic one week latercomplaining that the pain in his left calf area persistedand could be further aggravated by tiptoeing and weightbearing maneuvers....
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Báo cáo khoa học: "A novel approach to inhibit HIV-1 infection and enhance lysis of HIV by a targeted activator of complement" docx

... CentralPage 1 of 4(page number not for citation purposes)Virology JournalOpen AccessHypothesis A novel approach to inhibit HIV- 1 infection and enhance lysis of HIV by a targeted activator of ... surface-likemembrane cofactor protein (MCP), decay acceleratingfactor (DAF) and protectin (CD59), and the soluble factorH(fH) that can down-regulate complement activation atseveral stages of ... complement activator, CR2-Fc, can be used as a novel approach to HIV therapy by abrogating the complement-enhanced HIV infection of cells.Published: 12 August 2009Virology Journal 2009, 6:123...
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Báo cáo khoa học: " A novel approach to inhibit HIV-1 infection and enhance lysis of HIV by a targeted activator of complement" doc

... CentralPage 1 of 4(page number not for citation purposes)Virology JournalOpen AccessHypothesis A novel approach to inhibit HIV- 1 infection and enhance lysis of HIV by a targeted activator of ... complement activator, CR2-Fc, can be used as a novel approach to HIV therapy by abrogating the complement-enhanced HIV infection of cells.Published: 12 August 2009Virology Journal 2009, 6:123 ... complementactivation by the generation of many C3-fragments, such as C3dg and C3d. It has been demonstrated thatactivation of complement can enhance HIV infection through the binding of special complement...
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Báo cáo y học: " An integrated approach to diagnosis and management of severe haemoptysis in patients admitted to the intensive care unit: a case series from a referral centre" ppsx

... period and may provide a useful frame-work for the therapeutic management of haemoptysis in this clinical setting. To summarize, a multidisciplinary approach remains the cornerstone for the management ... and mycetoma. A simple set of clinical variables on admission combinedInitial management and short-term outcomeFigure 3Initial management and short-term outcome. †Life sustaining therapy was ... and management of severe haemoptysis in patients admitted to the intensive care unit: a case series from a referral centreMuriel Fartoukh*†1, Antoine Khalil†2, Laurence Louis†1, Marie-France...
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Báo cáo y học: " A stronger approach to weakness in the intensive care unit" doc

... distally in the Figure 1 A flow chart giving an approach to generalized weakness and/or ventilatory failure in the intensive care unit. CK, creatine kinase; CSF,cerebrospinal fluid; GBS, Guillain–Barré ... andtheir relative contributions to the weakness may varyconsiderably when this occurs. Elevated serum creatinekinase may help to identify CIM, but the peak may be missed in the membranopathy/necrotizing ... necessary if the needle biopsies are inadequate.Being aware of the incidence and signs of ICU-acquired weakness with ventilatory failure and having an approach to such disorders will prove valuable...
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Báo cáo y học: " A novel approach for prediction of tacrolimus blood concentration in liver transplantation patients in the intensive care unit through support vector regression" doc

... relevant input variables.BackgroundHospital information systems in intensive care medicine gener-ate large datasets on a daily basis. These rapidly increasingamounts of data make the task of ... models for tacrolimus blood concentration canimprove clinical care by optimizing monitoring of theseconcentrations, especially in the initial phase after transplantation during intensive care unit ... fewer variables: only 2 input variables were used instead of 15 and 16 variables by the linear methods. Apparently,these 2 input variables contained more information in a nonlin-ear way than the...
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Báo cáo y học: "A novel approach to modelling water transport and drug diffusion through the stratum corneum" pdf

... et al.: A novel approach to modelling water transport and drug diffusion through the stratum corneum. Theoretical Biology and Medical Modelling 2010 7:33.Submit your next manuscript to BioMed ... all the components of the tensor:KKKKKKKKKKxxzzxy xzyx yy yzzx zy=⎡⎣⎢⎢⎢⎤⎦⎥⎥⎥.Considering the mass flux of fluid into an REV, and by further d efining R* Δx y z to be the ... hcis the capillary rise and Pwis the capillary pressure between water and airin the porous m edium. Thus, we refer to “capillary head”, and the difference between the head pressures at the top...
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Báo cáo y học: " A statistical approach to estimating the strength of cell-cell interactions under the differential adhesion hypothesis" pptx

... contrast to these approaches, the mathematical back-ground of marked point processes allows the establish-ment of a statistical framework. In this study, we haveshown that our model was able to ... suggeststhat stationarity was indeed reached. Statistical estimation of the adhesion strength parameterIn this section, we study the sensitivity of simulationresults to the adhesion strength parameter ... CentralPage 1 of 13(page number not for citation purposes)Theoretical Biology and Medical ModellingOpen AccessResearch A statistical approach to estimating the strength of cell-cell interactions...
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Báo cáo y học: "A novel approach to identifying regulatory motifs in distantly related genomes" pps

... Article R113MethodA novel approach to identifying regulatory motifs in distantly related genomesRuth Van Hellemont*, Pieter Monsieurs*, Gert Thijs*, Bart De Moor*, Yves Van de Peer† ... successful in the identification of regulatory motifs, phylogenetic footprintingmethods still show some shortcomings. To assess these difficulties, most apparent when applyingphylogenetic footprinting ... more distantly related species can greatly improve the detection of conserved regulatory motifs. By adding more distantly related sequences, the conserved functional motifs can be more easilydistinguished...
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