... (NUTRIM), Department of Human Biology,Maastricht University, the NetherlandsGlutamine has an important function in the smallintestine with respect to maintaining the gut epithelialbarrier in ... intestinal cells obtain glutamine through exo-genous and endogenous routes. The exogenous gluta-mine comes from uptake of the amino acid itself or of glutamine-containing peptides from the intestinallumen ... compartment, similar tothe intestinal barrier in in vivo situations [27,28].ResultsUptake of glutamine by differentiating Caco-2 cells To determine whether the glutamine uptake is depend-ent...