understanding the role of drugs vaccines and funding
báo cáo hóa học: " Discrimination and reliability: equal partners? Understanding the role of discriminative instruments in HRQoL research: can Ferguson''''s Delta help? A response" pptx
... points Delta then indexes the degree to which the instrument makes valid discriminations Wyrwich suggests that the results of another study [6], in which the dichotomous scoring method of the GHQ-12 ... measure of discrimination would be useful if the discriminations observed were meaningful Recall that the value of Delta is derived from ordinal comparisons of persons that classify them as either the ... incorrect The magnitude of the reliability coefficient tells us nothing about the variability between subjects, and nothing about the extent to which people differ: indeed, this is the whole point of...
- 3
- 384
- 0
Tài liệu Báo cáo khoa học: Structural effects of a dimer interface mutation on catalytic activity of triosephosphate isomerase The role of conserved residues and complementary mutations pptx
... position 13 of the other subunit [25,26], yielding a covalently bridged dimer The 4170 oxidized and reduced forms of the Y74C mutant had very different thermal stabilities While the stability of the ... and in the presence of denaturants [27] Extending these studies, we examine here the effect of increasing the bulk of the residue at position 74 Surprisingly, the Y74W mutant exhibited loss of ... across the dimer interface, while T75 interacts with N10 and E97 of the second subunit The backbone NH group of R98 forms a hydrogen bond with the backbone CO of F102 Furthermore, the orientation of...
- 15
- 635
- 0
Báo cáo khoa học: The role of helix 8 and of the cytosolic C-termini in the internalization and signal transduction of B1 and B2 bradykinin receptors potx
... patterns of B2wt and of B1 ⁄ B2 chimeras reflect their agonist-inducible internalization The segment between the NPXXY motif and the conserved cysteine represents one of the regions with the highest ... influences the formation of a helical structure These authors proposed that activation of the receptor, and subsequently of the G protein, leads to a change in the environment of helix resulting in the ... to enhance their adherence Expression vectors The sequence of the human B2wt starting with the third encoded methionine [9], the sequence of the human B1wt, truncations and chimeras of both were...
- 12
- 595
- 0
Báo cáo khoa học: The role of residues R97 and Y331 in modulating the pH optimum of an insect b-glycosidase of family 1 pdf
... As the pKa values of the catalytic residues determine the pH optima, the ionization constants (pKa) of the catalytic glutamates (E187 and E399) in the ES complex and in the free enzyme (E) of ... the expression of the recombinant b-glycosidases Lysis of induced bacteria Fig Schematic representation of the Sfbgly50 active site E399 is the nucleophile and E187 is the proton donor Y331 and ... b-glucosidase affected the rate constant of the glycosylation step and also changed the enzyme pH optimum [14] Despite that, the effect of the tyrosine on the pKa values of the b-glycosidase catalytic glutamates...
- 10
- 522
- 0
Báo cáo khoa học: Dissecting the role of protein–protein and protein–nucleic acid interactions in MS2 bacteriophage stability potx
... urea-induced and GdnHCl-induced changes in the secondary structure of the proteins, we analyzed the UV CD spectra of MS2 and VLPs in the absence and presence of 5.0 m and 9.0 m urea and 3.5 m and 5.0 ... determined the effects on stability of genetic fusion of the two subunits of the dlFG dimer using the variant named 2CTdlFG, which takes advantage of the physical proximity of the N-terminus and C-termius ... Effect of pressure on the coat protein in the presence of bis-ANS for (n) dlFG and (e) sc-dlFG and in the absence of the probe for (m) dlFG and (r) sc-dlFG, was analyzed at room temperature The...
- 13
- 448
- 0
the role of labour mobility and informal networks for knowledge transfer
... for explaining the determinants of economic growth The focus on labor and capital as the primary factors of production, and the general exclusion or trivialization of the role of knowledge, was ... skilled labor, and technology The neo-technology theories focused on the role of R&D and the creation of new economic knowledge in shaping the comparative advantage and flows of foreign direct ... function of the number and concentration of permanent links 199 Dispersion as a function of the number and concentration of permanent links 200 Expertise as a function of the number and concentration...
- 230
- 396
- 0
báo cáo hóa học: " Understanding the role of discriminative instruments in HRQoL research: can Ferguson''''s Delta help?" docx
... the Hankins' paper, and there is no explanation for how the use of Ferguson's Delta would enhance interpretability Although the use of Ferguson's Delta may someday improve our understanding of ... allow the reader to know the basis of this validity assessment Moreover, no results on the relationship of the reported measures or items in Example and are provided Likewise, the third and perhaps ... demonstration of the usefulness of this novel psychometric method in HRQOL research that fully encompasses the intent of the taxonomy, integrates the relevant properties described above, and reflects the...
- 2
- 456
- 0
Báo cáo hóa học: " The role of feed-forward and feedback processes for closed-loop prosthesis control" doc
... (ADC) on the the microcontroller, streamed to PC software Position sensors were attached to the thumb and forefinger, the wrist and the base of the object, to enable accurate Saunders and Vijayakumar ... random unpredictable delays to the hand controller In contrast to experiments and 2, where the control of the hand was repeatable and predictable, this experiment was designed to examine the role ... briefly before the start of the first trial, with full feedback sensibility, so that they could get used to the control mechanism of the hand Subjects performed the four blocks of the experiment...
- 12
- 503
- 0
báo cáo hóa học:" The role of FGF-2 and BMP-2 in regulation of gene induction, cell proliferation and mineralization" pptx
... mineralizing RNA profile of igf-1, alp, and bmp-2 and significantly increased expression of other genes associated with mineralization like col1a1, fn, ilgf-1, noggin and oc Fgf-2, on the other hand, significantly ... matrix and promote healing [24] In this study, we have documented the relative efficiency of bone growth factors FGF-2, TGFb, and PGE2 markedly enhanced the synthesis of the total protein content of ... proliferation and mineralization [2,26-29] These two stages are the result of a specific sequential regulation of gene expression from the early phase of osteoblast proliferation to the final steps of mineralization...
- 8
- 547
- 0
báo cáo hóa học:" The role of FGF-2 and BMP-2 in regulation of gene induction, cell proliferation and mineralization" pdf
... mineralizing RNA profile of igf-1, alp, and bmp-2 and significantly increased expression of other genes associated with mineralization like col1a1, fn, ilgf-1, noggin and oc Fgf-2, on the other hand, significantly ... matrix and promote healing [24] In this study, we have documented the relative efficiency of bone growth factors FGF-2, TGFb, and PGE2 markedly enhanced the synthesis of the total protein content of ... proliferation and mineralization [2,26-29] These two stages are the result of a specific sequential regulation of gene expression from the early phase of osteoblast proliferation to the final steps of mineralization...
- 8
- 460
- 0
From Conflict to Peacebuilding The Role of Natural Resources and the Environment pdf
... equality, the rule of law and respect for and protection of human rights […] Recognizing the need to strengthen the important role of the United Nations in the prevention of violent conflicts, and ... emerged from the growing realization of the need to put the poor and all aspects of their lives and means of living at the centre of development and humanitarian work, while maintaining the sustainability ... and development activities, and requests the Secretary-General to submit a detailed review of the capacity of the United Nations system in the context of the report on the implementation of the...
- 50
- 468
- 0
Báo cáo khoa học: "The role of Bcl-xL and nuclear factor-kB in the effect of taxol on the viability of dendritic cells" ppsx
... rationale for the use of taxol in DC immunotherapy and insights into the development of combinational DC therapies with other anticancer drugs that not harm the viability or activity of DCs Acknowledgments ... (A) The optical density of each band was divided by that of the β-actin band, and the ratio at h was set at 100% (B) Fig NF-κB involvement in the taxol-induced effects on dendritic cells (DCs) The ... future study, the knockdown study of Bcl-xL using siRNA may further confirm their role of taxol-treated DCs Although the expression of Bax was increased in TaxolDCs, the expression of Bax occurred...
- 5
- 335
- 0
Báo cáo khoa học: " The role of marine salt and surfactants in the decline of Tyrrhenian coastal vegetation in Italy" ppt
... Finally, the comparison between the different behaviour of the species tested suggests that resistance to the action of aerosols is the result of the strength of the structures protecting the leaf, and ... illustrate the results of a number of experiments the aim of which was to measure the toxic- ity of the various components of polluted sea spray, both in isolation and in synergy MATERIALS AND METHODS ... collected both near the coast and 2-3 km inland Samples of bulk deposits were taken from pine trees (Pinus pinea L) from the section of the crown exposed to the sea and also from the opposite side...
- 11
- 371
- 0
Báo cáo y học: "The role of synovial macrophages and macrophage-produced cytokines in driving aggrecanases, matrix metalloproteinases, and other destructive and inflammatory responses in osteoarthritis" pps
... contribution of these two proinflammatory cytokines on the production of each other, on other proinflammatory mediators, on the expression and production of various MMPs and TIMPs, and on ADAMTS4 and ... as percentage of the production of untreated cells, and the standard error of the mean is given (n = 6–7) anisms behind the macrophage stimulation of other cells in OA cultures of synovial cells, ... or the combination of the two (p < 0.01) (Figure 4a) We also studied the effect of Enbrel and/ or the neutralising anti-IL-1β antibody on the spontaneous production of the major MMPs (1, 3, 9, and...
- 12
- 325
- 0
báo cáo khoa học: " Exploring the role of organizational policies and procedures in promoting research utilization in registered nurses" potx
... influencing the use of RBPs among staff nurses in the Canadian province of Newfoundland and Labrador with the specific aim of understanding the role of P&Ps in promoting research utilization Theoretical ... can be drawn Understanding of policies and procedures All nurses should have a basic understanding of what P&Ps are, and when and how to use them Fear of the legal ramifications of not following ... that the existence of practice policies was significantly associated with the use of only one of the eight practices examined However, we went a step further and examined whether the number of...
- 11
- 417
- 0
- enos uncoupling in cardiovascular diseases the role of oxidative stress and inflammation
- the role of teachers schools and communities in quality education
- explain the role of art music and dance in african society
- the role of students attitudes and motivation in second language learning in online language courses
- the role of sound music and sound effect in the film industry
- the role of oxidative stress and inflammation in dry eye disease
- the role of effective communication and interpersonal interaction in health and social care
- analyze the role of critical thinking and education for life
- what is the role of effective communication and interpersonal interaction in health and social care
- the role of oxidative stress and antioxidant treatment in experimental diabetic neuropathy
- the role of oxidative stress and endothelial injury in diabetic neuropathy and neuropathic pain
- the role of effective communication and interpersonal interaction in health and social care context
- the role of critical thinking and communication in the construction industry
- the role of oxidative stress and antioxidants in male infertility
- the role of teachers schools and communities in quality education a review of the literature
Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 sự cần thiết phải đầu tư xây dựng nhà máy phần 3 giới thiệu nguyên liệu