systems biology in psychiatric research from complex data sets over wiring diagrams to computer simulations
Tài liệu Báo cáo khoa học: Applications and trends in systems biology in biochemistry docx
... describing systems biology applied to biochemistry in the years 2000–2010 employing the ten most commonly used software tools models, lindo (Lindo Systems Inc., Chicago, IL, USA; www.lindo.com) ... makes systems biology research less tractable than it should be In our opinion, this must change In addition, terminologies in such an interdisciplinary field have to be chosen with care To exemplify ... kinase; IL, interleukin; IP3, inositol 1,4,5-triphosphate; IRS, insulin receptor substrate; JAK-STAT, janus kinase-signal transducer and activator of transcription, mitogen-activated protein kinase;...
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Báo cáo y học: " Review of "Systems Biology in Practice" by Edda Klipp, Ralf Hertwig, Axel Kowald, Christoph Wierling and Hans Lehrach" docx
... admit, the continuum hypothesis is unlikely to be valid in modelling many aspects of signal processing and transcriptional regulation Because of the rate of progress in systems biology, it seems ... is to be hoped that these (mostly minor) defects will be eliminated in the next edition However, they detract little from the value of the work as it stands I expect to consult it regularly over ... example, equation 3.21 (p 63) is incorrect, 'sites' is written for 'sides' (p 67) and 'mitochondrium' for 'mitochondrion' (p 168) In places, the writing would have benefited from the assistance of a...
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Báo cáo y học: "Integrating systems biology with clinical research" potx
... better suited to a fine-grained stratification of patients, allowing personalized therapies and decreasing the likelihood of overtreating or wrongly treating patients A complex interplay between ... consisting of the ErbB receptor family, AKT1 and MEK1 signaling intermediates, estrogen receptor alpha and Myc transcription factors, and cyclins D1 and E1 as well as cyclin-dependent kinases ... proteins in yeast exert their function in complexes with other proteins She stressed the point that protein complexes are, in general, highly dynamic structures, and often the same proteins are...
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Báo cáo hóa học: " Research Article Video Data Hiding for Managing Privacy Information in Surveillance Systems" ppt
... amount of distortion by setting δ close to zero, or the least amount of bit rate increase by setting δ close to one In order to avoid any overhead in communicating the embedding positions to the decoder, ... removal to be used Using data hiding for privacy data preservation is more flexible as it completely isolates preservation from modification Since our introduction of using data hiding for privacy data ... perceptually filled in the Obfuscation Unit using video in- painting as proposed in [14] The privacy object information is sent to the Secure Data Hiding unit to be encrypted and embedded inside the modified...
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Báo cáo hóa học: " Modeling Nonlinear Power Amplifiers in OFDM Systems from Subsampled Data: A Comparative Study Using " potx
... was born in Vitoria, ı Spain in 1967 He received his Telecommunication Engineer degree and his Ph.D degree in electrical engineering from the Polytechnic University of Madrid, Spain in 1991 and ... B.S degree in engineering and the Telecommunication Engineer degree from the Universidad de Cantabria, Spain in 1992 and 1995, respectively In 1995, he joined the Departamento de Ingenier´a de ... include nonlinear modeling techniques, adaptive systems, and machine learning theories and their application to digital communication systems ´ Jesus Ib´ nez was born in Santander, Spain a˜ in 1971...
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Báo cáo y học: "The Inferelator: an algorithm for learning parsimonious regulatory networks from systems-biology data sets de novo" pptx
... is similar to that on the training data (the mean RMS over the training set is within standard deviation of the mean RMS over the new data) , indicating that our procedure is enforcing reasonable ... limiting the set of potential predictors to include only TFs, and grouping together regulators that are in some way similar) In the latter case, gene expression clustering, or unsupervised learning ... edges), but tolerance to noise, irregular sampling, and undersampling is difficult to assess at this point Using cMonkey as a preliminary step to determine co-regulated groups also helps us to resolve...
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SCIENTIFIC BASIC RESEARCH FOR ESTABLISHING DATA TOPOGRAPHIC MAP IN SERVICE OF MILITARY PURPOSE FROM GEOGRAPHICAL DATABASE AND REMOTE SENSING IMAGE
... in building and updating map database 2.2.1 Digital map 2.2.2 Building map database 2.2.3 Updating database by remote sensing image 2.3 Building database 2.3.1 Factors affecting to the building ... managing, sharing data of military topographic map, contributing to supporting the efficient exploitation of topographic information, expanding to many different objects having knowledge about information ... background database covering multi-purpose as original documentation to derive into database for many different purposes Therefore, it is necessary to study the ability to organize mapping database in...
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RESEARCH ON THE CHANGE OF 2-AP AND OTHER VOLATILE COMPOUNDS IN PROCESSING BUN FROM RICE
... 3°C/min then from1 15°C to 220°C at 30°C/min and finally maintained at 220◦C for The detector port was maintained at 2500C Concentration of 2-AP in samples s is identified and quantified in the ... 400C for minutes, the following temperature programs were applied: - For SDE: from 400C to 2200C at a rate of 30C/min and finally maintained at 2200C for min; - For SPME: from 40°C to 115°C at ... transfer line and the Fig Adsorption phase in SPME extraction injector temperature were respectively maintained at 260°C and 250°C He at ml/min was the carrier gas The column was maintained at...
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Tài liệu Combining Data in Tables from Heterogeneous Data Sources docx
... heterogeneous data sources to be accessed without setting up linked servers by providing the information required to connect to each data source in the SQL statement This is done using either the ... supports two methods to access data from heterogeneous data sources through OLE DB: linked servers and ad hoc connector names You can refer to linked servers in SQL statements using a four-part name ... SqlDataAdapter da = new SqlDataAdapter(sqlSelect, ConfigurationSettings.AppSettings["Sql_ConnectString"]); DataTable dt = new DataTable( ); da.Fill(dt); // Set up and bind a view with data from...
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Tài liệu PTSD in Women Returning From Combat: Future Directions in Research and Service Delivery doc
... needed into developing appropriate screening and treatment of PTSD for service members returning from combat and reentering into the private sector Summary: Developing a Research Agenda and Improving ... sector and VA providers need to be developed to overcome private sector physicians’ fear of ‘losing’ patients to the VA system Private sector clinicians need more and better tools for opening ... contributing factor to PTSD in men and women returning from combat A 2008 study of combat service members found that almost half of service members suffering from mild traumatic brain injuries...
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Tài liệu Environmental impacts of petroleum production: Fate of inorganic and organic chemicals in produced water from the Osage-Skiatook Petroleum Environmental Research sites, Osage County, Oklahoma doc
... available Historical methods included discharge into surface streams, storage in unlined impoundments, disposal in poorly maintained injection wells, and simply running the water over the ground ... eroded to depths of as much as m Seepage of salt water from a shallow sandstone aquifer continues and active salt scarring persists This area drains into the Cedar Creek arm of Skiatook Lake Drilling ... scarring, soil salinization and oil contamination, and brine and petroleum contamination of ground water and surface water, including Skiatook Lake, a 4,250-hectare reservoir that provides drinking...
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Tài liệu Báo cáo khoa học: A systems biology approach for the analysis of carbohydrate dynamics during acclimation to low temperature in Arabidopsis thaliana doc
... et al ¨ how to engineer plant metabolism in order to improve freezing tolerance, one could suggest increasing the maximum activities of enzymes participating in sucrose cycling Assuming that Rsch ... [20,24] However, it has to be kept in mind that the sink export rate in our model is composed of assimilate export to sink organs and flux into further pools of carbon-containing metabolites and structural ... rapidly become integrated into metabolic research, driven by the need to study complex interactions among components of biological systems [16] Basically, the intention of systems biology is Fig...
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Báo cáo khoa học: Measuring enzyme activities under standardized in vivo-like conditions for systems biology pdf
... enzyme–kinetic data, including a precise description of the assay conditions [9,10] Strict adherence to these standards in public databases will be of great help in evaluating the data for use in computer ... at least three independent cell-free extracts from steady-state samples from a single chemostat culture Enzyme In vivo-like Vmax (mmolÆmin)1Æg protein)1) Flux (mmolÆmin)1Æg protein)1) HXK PGI ... shown in Table The in vivo-like Vmax values were sufficient to support the maximal flux Discussion In order to support coordinated efforts to standardize experimental conditions for systems biology, ...
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Báo cáo khoa học: Metabolomics, modelling and machine learning in systems biology – towards an understanding of the languages of cells potx
... are many things one might wish to with an SBML or other biochemical model, including creating it, storing it, editing it, comparing it with other stored models, nding it again in a principled way, ... is in addition a large historical database of facts that could be useful to systems biology Text mining is an emerging eld concerned with the process of discovering and extracting knowledge from ... proling data using machine learning Plant Physiol 126, 943951 Kell DB (2002) Metabolomics and machine learning: explanatory analysis of complex metabolome data using genetic programming to produce...
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BÁO CÁO "RESEARCH ON THE CHANGE OF 2-AP AND OTHER VOLATILE COMPOUNDS IN PROCESSING BUN FROM RICE" doc
... 3°C/min then from1 15°C to 220°C at 30°C/min and finally maintained at 220◦C for The detector port was maintained at 2500C Concentration of 2-AP in samples s is identified and quantified in the ... 400C for minutes, the following temperature programs were applied: - For SDE: from 400C to 2200C at a rate of 30C/min and finally maintained at 2200C for min; - For SPME: from 40°C to 115°C at ... transfer line and the Fig Adsorption phase in SPME extraction injector temperature were respectively maintained at 260°C and 250°C He at ml/min was the carrier gas The column was maintained at...
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Báo cáo khoa học: Systems biology: model based evaluation and comparison of potential explanations for given biological data pot
... conceptual introduction to the whole article Introductory example The example is concerned with insulin signaling, and is inspired by the developments in [12] Insulin signaling occurs via the insulin ... active already during the first few minutes in response to insulin, and it is only the first few minutes that are observed in the experimental data Therefore, it is interesting to consider explanations ... for the insulin signaling example in the introductory example are depicted The top one includes both internalization and recycling after dephosphorylation, but not the lower one The figure to the...
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Visual Event Recognition in Videos by Learning from Web Data ppt
... Rochester in Fall 2011 His research interests include image processing, machine learning, computer vision, social multimedia data mining, biomedical informatics, and ubiquitous computing He has ... three consumer videos from each event (18 videos in total) as the labeled training videos in the target domain, and the remaining videos in the target domain are used as the test data We sample the ... IN VIDEOS BY LEARNING FROM WEB DATA In A-SVM, the auxiliary classifiers are learned by using only the training samples from the auxiliary domain In contrast, the prelearned classifiers used in...
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Báo cáo khoa học: From functional genomics to systems biology Meeting report based on the presentations at the 3rd EMBL Biennial Symposium 2006 (Heidelberg, Germany) Sergii Ivakhno pot
... Functional genomics and systems biology S Ivakhno Table Overview of the topics covered in the meeting report according to systems biology applications, types of high-throughput ... (Boston, MA, USA) He described the chromosome conformation capture methodology which uses formaldehyde cross-linking to covalently link interacting chromatin segments in intact cells [5] Cross-linked ... suggested that individual research groups should continually contribute small subnetworks to the global interactome repository in the way it was done during sequencing of the human genome The incompleteness...
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quinkert - essays in contemporary chemistry - from molecular structure towards biology (wiley, 2001)
... dozen laboratories in the world working on protein structure: Perutz and Kendrew in Cambridge working on haemoglobin and myoglobin, Dorothy Hodgkin in Oxford on insulin, David Harker in Brooklyn ... building in molecular biology, the forerunner of the untold investment in computer- assisted molecular modeling in present day research I am pleased that I helped to give it its name The following ... the structure of the ri- FROM MOLECULAR STRUCTURE TOWARDS BIOLOGY 21 bosome with fascinating insights into the mechanism of the protein making machinery There seems to be no end There may be...
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essential issues in soc design - designing complex systems-on-chip - y. lin (springer, 2006) ww
... parts of the SOC To integrate it into the SOC, we have to collaborate with the original vendor to create synthesis, simulation and test models in addition to hardening the processor into a high-speed ... optimizing probe card overdrive spec, optimizing power relay waiting time, and retargeting Isat and Vth by optimizing poly CD in the foundry according to results from corner lot splitting A ... problem An NoC brings the computer networking technology (i.e., packet routing) to the SOC in order to simplify the design and management of communication among IPs in an SOC To design a complex SOC,...
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