how many plants and animals are there in the amazon rainforest
nuclear import and export in plants and animals - t. tzfira, vitaly citovsky
... of the nucleic acid-binding affin-ity of the zinc finger domain, and therefore most likely mediated by protein-protein interac-tions. In a search for protein-protein interaction partners, and ... bindingis reduced as W1W2 repeats are deleted, indicating that their copy number is involved in high-affinity binding. Fine mapping indicated that the 10 amino acid segment EPRRVRRRVL in the ... Nuclear Import and Export in Plants and Animals 8conserved. They contain roughly the same mass and occupy the same volume as the correspond-ing unit in the normal pore. In other words the larger...
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Báo cáo sinh học: "Adaptive evolution of centromere proteins in plants and animals" ppt
... is rapidly evolving in plants and animals, so adaptation of the major centromere DNA-binding proteins would maintain an interface with the con-served kinetochore machinery. Indeed, regions ... CENP-C proteins in animals, yeast and plants. The CENPC motif and conserved regions found at the termini of CENP-C proteins are indicated. For pairwise comparisons of protein-coding sequences, ... Mif2pproteins, but others align only at conserved regions. Portions of the human CENP-C protein implicated in centromere-targeting (purple bars) and DNA-binding (black bars) are shown at the top. The...
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Báo cáo y học: "Vive la différence: biogenesis and evolution of microRNAs in plants and animals" ppt
... reads in Ago-IP samples.)Perhaps more importantly, there are few data on how ‘well’ a miRNA hairpin is processed. If only 1% of a miRNA hairpin transits the processing machinery, and these are ... duplex is shown, but there can be several such duplexes depending on the length of the stem. These are transported from the nucleus via HASTY, an Exportin5 (Exp5) homolog, for loading into an Argonaute ... substrates, including hairpin RNAs (hpRNAs). ese long structured hairpins resemble long miRNA hairpins, in that they have internal mismatches and bulged positions; however, they are not processed...
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Báo cáo khoa học: The starch-binding capacity of the noncatalytic SBD2 region and the interaction between the N- and C-terminal domains are involved in the modulation of the activity of starch synthase III fromArabidopsis thaliana pdf
... confirmed the results obtained in the pull-down assays, showing that there is a physicalinteraction between the N- and C-terminal domains ofSSIII in vitro.Mapping of the CD-binding region in the N-terminal ... not the individual starch-binding domains, are involved in the interaction with the catalytic domain. We also determined that the resi-dues W366 and Y394 in the D2 domain are important in starch ... CD–23 and CD–St2.1, butnot for the CD–St2.2 protein, showing the importanceof the interacting region in the D2 domain and the lin-ker region connecting CD and SBDs for full SSIIIactivity. In...
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Báo cáo khoa học: Apo a-lactalbumin and lysozyme are colocalized in their subsequently formed spherical supramolecular assembly doc
... isnear 4–5) and their calcium-binding properties (a-lact-albumin has a specific calcium-binding site). Interest-ingly, the formation of spherical particles containing the two proteins in an equimolar ... performed using the standardmode for the acquisition of images and the spectral modefor the acquisition of the spectra of the dyes. For the acqui-sition of images using the standard mode, FITC and ... protein molecules can be incorporated.However, the precise internal organization is stillunknown; in particular, how solvent molecules are sequestered and how both proteins are arranged in the three-dimensional...
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Báo cáo khoa học: Sp1 and Sp3 are involved in up-regulation of human deoxyribonuclease II transcription during differentiation of HL-60 cells pptx
... anti-Sp3 IgG, indicating they contain proteinsother than Sp1 or Sp3. It is not clear whether theseunknown factors interact with Sp1 or Sp3, facilitating theirbinding to GC-I and enhancing their transcriptional ... be involved in increasing the DNA binding and transcriptional activities ofSp1. As shown in Fig. 4A, two DNA–protein complexesother than C1, C2, and C3 were detected in PMA-treatedcells, the ... Sp1 and Sp3 are able to bind to the GCboxes and that binding of Sp1 forms complex C1 and binding of Sp3 forms complexes C2 and C3.PMA treatment increases Sp1 and Sp3 proteinexpression in HL-60...
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báo cáo hóa học: " Indoors illumination and seasonal changes in mood and behavior are associated with the health-related quality of life" pdf
... challenge these time-keeping mechanisms ofaction as, for instance, the evening-active cells yield the dominance to the morning-active cells within the princi-pal circadian clock following the shortening ... 2000 and July 2001. The two-stage stratified cluster sampling designwas planned by Statistics Finland. The sampling framecomprised adults aged 30 years and over living in main-land Finland. ... signing, and a questionnairecontaining self-reports such as the SPAQ, the 15D, the GHQ-12 and the Beck Depression Inventory (BDI) thatinterviewees were asked to fill in and bring along to the health...
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Báo cáo y học: "QTc and psychopharmacs: are there any differences between monotherapy and polytherapy" ppsx
... significantly in the monotherapy and the polytherapy group. More than one third of included women exceeded the thresholdvalue of borderline QTc interval (450 ms) before starting treatment. This finding ... when used in combination.Concomitant use of antipsychotics and antidepressants is not rare in our clinical practice. The studycompares the length of QT interval in patients on monotherapy with ... conceived of the study, performed the statistical anal-ysis and helped to draft the manuscript. VB, PB, MH and MSŠ participated in the design of the study and collectingpatients for inclusion and helped...
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Báo cáo y học: " MRI bone oedema scores are higher in the arthritis mutilans form of psoriatic arthritis and correlate with high radiographic scores for joint damage" ppt
... imaging of the wrist; the patientwas repositioned so that the fingers were within the coil; and then enhanced imaging of the fingers was performed. Boneoedema was investigated using short tau inversion ... pertain only to baseline findings in thesepatients, before administration of the study drug or placebo.All patients gave informed consent according to the require-ments of the New Zealand Multiregion ... scores (skin or joint) or inflammatorymarkers. Interestingly, the MRI bone oedema score was alsohigher in the AM group and correlated strongly with erosion and joint space narrowing scores. These...
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Báo cáo y học: "Reduced proportions of natural killer T cells are present in the relatives of lupus patients and are associated with autoimmunity" ppt
... cytokinesthat are secreted by the NKT cells in the different lupus mousemodels, with interleukin-4-secreting NKT cells inhibiting lupus and interferon-γ-secreting NKT cells exacerbating lupus[53,54,56,57]. ... stained with various combinations of conjugated mAbs, fixed, and analyzed by flow cytometry (as outlined in the Materials and methods section and shown in Figure 1). (a) Shown are plots for the ... for the classification of SLE and had two living parents who agreed to participate in the study. In total 144 patients, 288 parents, and 79 siblings wereinvestigated. Population control individuals...
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Báo cáo y học: "MRI bone oedema scores are higher in the arthritis mutilans form of psoriatic arthritis and correlate with high radiographic scores for joint damage" ppsx
... and, where there was disagreement byconsensus, blinded to clinical and MRI findings.Clinical definition of arthritis mutilansClinical digitised photographs of the hands and feet wereobtained ... unenhanced imaging of the wrist;contrast injection; enhanced imaging of the wrist; the patientwas repositioned so that the fingers were within the coil; and then enhanced imaging of the fingers was ... sequences and acquisitions are shown in Table 1. The sequence of imaging was as follows: unenhanced imag-ing of the fingers; the patient was repositioned so that the wrist was within the coil;...
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HANDBOOK OFCHEMICAL RISK ASSESSMENT Health Hazards to Humans, Plants, and Animals ( VOLUME 1 ) - PART 1 ppsx
... electroplating ofmotor parts and in the manufacture of batteries. The cadmium load in soils and terrestrial biota in other industrialized countries also appears to be increasing and is of great ... 1980). During anaerobic conditions in the lake’shypolimnion, a marked decrease in the dissolved fraction and a corresponding increase in the suspended fraction were noted. The dominant form ... organotins into air, soil, and water8.5 Total tin flux to the atmosphere and hydrosphere8.6 Tin concentrations in nonbiological materials8.7 Tin concentrations in field collections of living flora and...
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HANDBOOK OFCHEMICAL RISK ASSESSMENT Health Hazards to Humans, Plants, and Animals ( VOLUME 1 ) - PART 2 pptx
... practices in North America and Europe have increased the proportionof women among workers in nickel mines and refineries and in nickel-plating industries and haveincreased the concern regarding possible ... excreted in the urine during the first 3 days after injection in rats and during the first day in rabbits (Norseth 1986). Exhalation via the lungs is the primary route ofexcretion during the first ... agree that albumin is the main transport protein for nickel in humans and animals and that nickel is also found in nickeloplasmin — a nickel-containing alpha-macro-globulin — and in an ultrafilterable...
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HANDBOOK OFCHEMICAL RISK ASSESSMENT Health Hazards to Humans, Plants, and Animals ( VOLUME 1 ) - PART 3 ppsx
... widely used herbicide in the Chesapeake Bay watershed — and in the surrounding coastal plain — has been atrazine. Since its introduction into the region in the early 1960s, atrazine use has grown ... 1987). The total amount of atrazine reaching the Wye River, Maryland, estuary depended on the quantity applied in the watershed and the timing of runoff. In years of significant runoff, 2 to 3%of the ... and Angle 1987). Most of the atrazine in surface runoffwas lost during the first rain after application. In 1979, the year of greatest precipitation, 1.6% of the atrazine applied moved from the...
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HANDBOOK OFCHEMICAL RISK ASSESSMENT Health Hazards to Humans, Plants, and Animals ( VOLUME 1 ) - PART 4 doc
... chitin by insects and of HA byvertebrates, and because diflubenzuron interferes with the incorporation of UDPAGA into chitinby insects, diflubenzuron may interfere with the formation of HA in ... weeks in water containing 3.2 àg diazinon/L (Allison and Hermanutz 1977), in yearlingbrook trout (Salvelinus fontinalis) within a few weeks at 4.8 àg/L (Allison and Hermanutz 1977), and in various ... reactions to chitin chains in the outer mantle epithelium secretory cells, producing unstabilized chitin and increasing shellfragility. On this basis, the comparatively resistant burrowing bivalve...
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