các dạng hư hỏng của thịt do vi sinh vật
Báo cáo y học: "Primary prevention of Down’s syndrome"
... evidence for an effect comes from a study of French donor insemination centres, where there is a large age difference between donors and recipients [27] A statistically significant effect of donor ... interviewer takes a clinical history from the mother, including about previous affected pregnancies The study identified five cases of Down’s syndrome occurring among 5404 pregnancies previous ... prevent fetal neural tube defects (NTDs) might incidentally reduce the DS risk provided a high enough dose is used 4.1 Evidence of a link A study of 41 mothers of DS infants found a statistically significant...
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Handbook of Tourette''''s Syndrome and Related Tic and Behavioral Disorders, Second Edition doc
... Conneally VII 411 427 455 467 475 SPECIAL TOPICS 25 The Child and Adolescent with Tourette’s Syndrome: Clinical Perspectives on Phenomenology and Treatment James F Leckman and Donald J Cohen 481 viii ... OCD when behavioral problems develop later in the course of TS (2,10,13) Although the natural history of various behavioral problems has not been well documented, there is some evidence that ... (10), involving 179 adult patients, and by Musisi et al (48), involving 33 patients (both adolescents and adults)—were patients under the care of physicians Musisi et al found an overall downward...
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Cushing''''s Syndrome pdf
... another, little is known about what makes these tumors occur There does not appear to be any specific genetic, immune, or environmental factor HOW COMMON IS CUSHING'S SYNDROME? Iatrogenic Cushing's ... disease, some allergies, and others Spontaneous overproduction of cortisol in the adrenals is divided into two groups those due to an excess of ACTH and those that are independent of ACTH A pituitary ... "iatrogenic" (caused by the treatment) form is unfortunately a necessary side effect when high doses of these steroid hormones must be used to treat certain life-threatening illnesses, such as...
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HOW IS CUSHING''''S SYNDROME DIAGNOSES? pptx
... abnormal, usually a day test divided into low and high dose dexamethasone is needed To separate ACTH dependent from independent types, a blood test for ACTH in the morning is done Blood and urine tests ... doing a dexamethasone suppression test Dexamethasone (steroid) pills are given by mouth, then blood and urine are collected for cortisol and other adrenal hormones A screening test might be done ... injured in order to cure the Cushing's disease, leaving the person with a deficiency of ACTH and the other pituitary hormones This can be treated by giving replacement hormones for cortisol, thyroid...
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HỘI CHỨNG CUSHING (Cushing’s syndrome) ppt
... (carcinoma) vỏ thượng thận, giảm bình thường có u lành (adenoma), cường sản vỏ thượng thận bình thường tăng + Các xét nghiệm để chẩn đoán phân biệt hội chứng Cushing bệnh Cushing (do cường thùy ... + X quang thượng thận có bơm sau phúc mạc chụp thận có bơm thuốc cản quang phát thấy khối u thượng thận + Chụp CT scanner thượng thận + Chụp cộng hư ng từ: thấy khối u nhỏ, đo kích thước vị trí ... Ung thư thai, ung thư buồng trứng, ung thư tế bào phổi, khối u đại tràng, u tuyến ức mà thân khối u tiết chất giống ACTH (hormon like) Bệnh có nhiều nguyên nhân hậu gây cường tiết hormon vỏ thượng...
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Báo cáo y học: "Genetic aspects of Sjögren’s syndrome" pptx
... syndrome Arthritis Rheum 2001, 44:176-179 Rischmueller M, Limaye V, Lester S, Downie-Doyle S, Pile K, Bardy P, Gordon TP: Polymorphisms of the interleukin 10 gene promoter are not associated with ... confirmed The IL-1 receptor antagonist regulates IL-1 activity in inflammatory disorders by binding to IL-1 receptors and thus inhibiting the activity of IL-1 The human IL-1 receptor antagonist gene ... fully understood It is not known how tolerance breakdown and autoantibody response to Ro/SSA and La/SSB is generated The ribonucleoproteins are endogenous proteins that are normally hidden from the...
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Báo cáo y học: "α Anti-α-fodrin antibodies do not add much to the diagnosis of Sjögren’s syndrome" pot
... Fourteen sera contained anti-Ro60 (SS-A) antibodies (sensitivity 67%) and 13 sera contained anti-La (SS-B) antibodies (sensitivity 62%) These activities were confirmed by at least one other technique ... confirm the presence of antiRo and anti-La antibodies, as previously described [16] Immunoblotting To confirm the ELISA results, reactivity of sera against recombinant fodrin–GST was evaluated by ... detection of anti-α-fodrin antibodies and showed that IgA antibodies against α-fodrin provided an even higher sensitivity than IgG antibodies [12] The objective of this study was to measure the presence...
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báo cáo khoa học: "Scintigraphic features of Morquio’s syndrome: a case report" pptx
... case report and review of clinical findings N Y State Dent J 1998, 64:48-50 Mikles M, Stanton RP: A review of Morquio syndrome Am J Orthop (Belle Mead NJ) 1997, 26:533-540 doi:10.1186/1752-1947-5-42 ... any accompanying images A copy of the written consent is available for review by the Editor-in-Chief of this journal Abbreviations MBq: megabecquerel; Tc-99m: metastable technetium-99 Authors’ ... Accepted: 28 January 2011 Published: 28 January 2011 Figure Localized anterior bone scan view of the pelvis of a 46-year-old Caucasian man with Morquio’s syndrome demonstrating bilateral hip replacements...
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Báo cáo khoa hoc:" Effectiveness of low-dose doxycycline (LDD) on clinical symptoms of Sjögren''''s Syndrome: a randomized, double-blind, placebo controlled cross-over study" potx
... is independent from their antimicrobial effect [20] Doxycycline given in low doses (low-dose doxycycline, LDD) decreases significantly MMP activity by multiple mechanisms in the inflammatory diseases ... All the patients were women This was a randomized, double blind, placebo-controlled clinical trial, and the patients were randomized at the baseline Randomization was performed by use of a computer-generated ... the onset of the study according to the need The patients were randomly assigned to receive either lowdose doxycycline (20 mg doxycycline; Periostat®; further referred as LDD) or matching placebo...
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Báo cáo y học: "A possible variant of Bouveret’s syndrome presenting as a duodenal stump obstruction by a gallstone after Roux-en-Y gastrectomy: a case report" pot
... abandoned early to reduce the risk of small bowel perforation A forward-viewing endoscope may be safer than a side-viewing endoscope in this group of patients and has been recommended previously ... patients with Billroth II gastrectomy: a comparative study of the forward-viewing endoscope and the side-viewing duodenoscope Endoscopy 1997, 29:82-85 Galloway SW, Chan AC, Chung SC: Transhepatic balloon ... syndrome: a comprehensive review of 128 cases Am J Gastroenterol 2006, 101:2139-2146 Hintze RE, Adler A, Veltzke W, Abou-Rebyeh H: Endoscopic access to the papilla of Vater for endoscopic retrograde...
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Báo cáo y học: " Adrenocortical oncocytic neoplasm presenting with Cushing''''s syndrome: a case report" pot
... 1992, 27:263-304 Bisceglia M, Ludovico O, Di Mattia A, Ben-Dor D, Sandbank J, Pasquinelli G, Lau SK, Weiss LM: Adrenocortical oncocytic tumors: report of 10 cases and review of the literature Int ... manuscript and revised the draft over the course of submission DS coordinated the design and drafting of the initial version and revised the draft over the course of submission GO carried out endocrinological ... prediction of biologic behavior and clinical outcome can be difficult There is no single histological parameter that is predictive of the clinical outcome and biologic behavior of adrenocortical...
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Báo cáo y học: " Pathogenic effect of interleukin-17A in induction of Sjögren’s syndrome-like disease using adenovirus-mediated gene transfer" docx
... adenovirus vectors used in this study were generously provided by Dr Jay K Kolls (Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA) These vectors are based on the first generation adenovirus ... baseline levels or with C57BL/6J mice receiving the control Ad5LacZ vector at 10 viral particles per salivary gland, demonstrating the efficacy of this viral vector to produce IL-17A In addition, ... He et al [40] provided evidence that ductal cannulation of salivary glands can also have systemic effects due to the secretory nature of the salivary glands which are well endowed with protein...
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Cushing’s Disease in Children: Report of Three Cases potx
... syndrome J Clin Endocrinol Metab 2001;86:5711−4 Davies JH, Storr HL, Davies K, et al Final adult height and body mass index after cure of paediatric Cushing’s disease Clin Endocrinol (Oxf) 2005;62:466−72 ... syndrome in children and adolescents: current diagnostic and therapeutic strategies J Endocrinol Invest 2002;25:181−94 Leinung MC, Zimmerman D Cushing’s disease in children Endocrinol Metab Clin North ... specific drugs had been prescribed previously Although she had visited other hospitals, no diagnostic conclusion had been reached She also experienced regressive behavior, depression, and poor school...
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báo cáo hóa học:" Rapid serological detection of autoantibodies associated with Sjögren''''s syndrome" docx
... 2005, 38:55-63 Kapogiannis B, Gussin HA, Teodorescu MR, Teodorescu M: Differences in clinical sensitivity of ELISA tests for autoantibodies with human and bovine extractable nuclear antigens Lupus ... positive Previously, we found that all individuals have detectable anti-Ro52 antibodies by LIPS [20] However, unlike the normal range of anti-Ro52 antibody titers in healthy individuals, some ... assays; WHR, provided patient sera from cohort with clinical information and was involved in critical revision; MJI helped develop the high-throughput assay and was involved in critical revision and...
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báo cáo hóa học: " Primary Sjögren''''s Syndrome: health experiences and predictors of health quality among patients in the United States" potx
... We documented reduced functioning among PSS patients in every domain of the SF-36, and increased utilization of health care services including medications, hospitalization rates, provider visits ... experienced, treatments used, provider visits, hospitalizations within the past years, dental visits and costs of dental care as well as the overall impact of Sjogren's on activity, family and social ... Patients (n = 201): Sicca severity (domain from SSI) Somatic fatigue (domain from PROFAD-SSI) Mental fatigue (domain from PROFAD-SSI) Depression (CES-D) Pain severity (domain from BPI) Age Duration...
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Báo cáo y học: "Psychiatric disorder as clinical presentation of primary Sjögren’s syndrome: two case reports." pdf
... outpatient psychiatry service for the treatment of a depressive episode, characterised by depressed mood, anhedonia, anorexia with weight loss, hypersomnia, diminished libido, and poor concentration ... was diagnosed (structured clinical interview for DSM-IV axis II personality disorders (SCID-II)) Paroxetine (at a dose of 20 mg/day) and alprazolam (at a dose of mg/ day) were given and partially ... was given at a dose of 40 mg/day and was tapered gradually using alternate day method After being treated with prednisolone, citalopram (at a dose of 40 mg/day), and lorazepam (at a dose of mg/day)...
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Báo cáo y học: "Abnormalities of B cell phenotype, immunoglobulin gene expression and the emergence of autoimmunity in Sjögren’s syndrome" pdf
... recep- Recent studies in patients with RA [9,54,55] provided evidence that receptor editing/revision might also be more active in the synovium of these patients than in normals In contrast with ... subsequent Ig rearrangements by downregulating the expression of recombination activating gene (RAG) and RAG2 enzymes in the bone marrow However, recent studies provide evidence that immature B cells ... related to lupus disease activity, analysis in pSS [40] showed a clear predominance of CD27– naive B cells (Fig 1) that also lacked expression of CD5 compared with normal donors as well as patients...
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Báo cáo y học: "Genetic control of disease in an experimental model for Sjögren’s syndrome Åsa Andersson" potx
... from the Tnfsf4 gene encoding the OX40 ligand (OX40L) This molecule negatively influences the activity of type regulatory T cells [7,8], thereby possibly contributing to autoimmunity The other pathway ... background Arthritis Rheum 2002, 46:1390-1398 Johannesson M, Karlsson J, Wernhoff P, Nandakumar KS, Lindqvist AK, Olsson L, Cook AD, Andersson Å, Holmdahl R: Identification of epistasis through a partial ... Ito T, Wang YH, Duramad O, Hanabuchi S, Perng OA, Gilliet M, Qin FX, Liu YJ: OX40 ligand shuts down IL-10-producing regulatory T cells Proc Natl Acad Sci USA 2006, 103:1313813143 Takeda I, Ine...
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Báo cáo y học: "Increased circulating levels and salivary gland expression of interleukin-18 in patients with Sjögren''''s syndrome: relationship with autoantibody production and lymphoid organization of the periductal inflammatory infiltrate" pptx
... infiltrates, double IHC was performed for CD68/IL-18 using the DAKO EnVision Doublestain System Briefly, for double staining, after antigen unmasking with 0.1% trypsin in PBS, endogenous peroxidase ... Sections were double-stained for CD3 (T cells) and CD20 (B cells) using the DAKO EnVision Doublestain System and single-stained for FDC (CD21) For CD3/CD20 double staining, we adopted the same ... classified as having SS on the basis of the recently revised criteria of the American–European Consensus Group [34] The presence of other, underlying autoimmune diseases or hepatitis C virus infection...
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Báo cáo y học: "Analysis of immunoglobulin light chain rearrangements in the salivary gland and blood of a patient with Sjögren’s syndrome" pptx
... anti-CD19 antibodies and FACS sorting of individual B cells were carried out as previously described for peripheral blood B cells [9–11] A total of 188 individual CD19+ B cells obtained from the parotid ... blood of two healthy normal donors (26 and 45 years old) analyzed previously [10,11] were used for comparison Both the nonproductive and productive repertoires of these donors exhibited a comparable ... negative selection of these Vλ gene segments Mutations within each codon were analyzed and expressed as the percentage of individual codons with replacement or silent mutations Mutational ‘hot spots’...
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