ambiguous conflicting if their findings vary widely with regard to the direction statistical significance and clinical significance size of the effect
Báo cáo khoa học: Expressed as the sole Hsp90 of yeast, the a and b isoforms of human Hsp90 differ with regard to their capacities for activation of certain client proteins, whereas only Hsp90b generates sensitivity to the Hsp90 inhibitor radicicol pdf
... arise with mutation to Hsp90, with altered cochaperone function and with the loss of plasma membrane drug efflux pumps [35] The results of this study point to the two isoforms of human cytosolic ... interaction of these MAP kinases with the two isoforms of human Hsp90 was strengthened by heat shock (Fig 5A) The stronger interaction of ERK5 with Hsp90b, relative to Hsp90a, was then confirmed ... signaling to Mkk1 ⁄ 2p [3,14,18] We used the yeast two-hybrid (Y2H) system to determine the relative strengths of in vivo interaction of these two MAP kinases with the two isoforms of human Hsp90 In the...
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Báo cáo y học: "Diagnostic value and clinical laboratory associations of antibodies against recombinant ribosomal P0, P1 and P2 proteins and their native heterocomplex in a Caucasian cohort with systemic lupus erythematosus" pot
... full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis RB, CD, FH and WSchlumberger contributed to study design ... and 11 (7.8%) positive for aRibPR2 Some of those sera were further exclusively positive for one of the recombinant aRibPs and showed an increased titer up to twofold of the corresponding cutoff ... Fisher’s exact test; dstatistically significant findings, highlighted in bold; eGGT values of men and from other laboratories have been standardized on cutoffs of GGT for women at the Charité University...
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Báo cáo khoa học: "Entailment-based Text Exploration with Application to the Health-care Domain" pot
... Fragment of the entailment graph for ‘asthma’ (top), and its conversion to a DAG (bottom) Figure 4: The roots of the entailment graph for the ‘asthma’ query 3.2 Exploration Scheme The objective of the ... as the roots of the DAG As a starting point, only the roots of the DAG are displayed to the user Figure shows the five roots for the ‘asthma’ query Exploration process The user selects one of the ... service handles the logic of the entailment relations (for both the entailment graph and the taxonomy) The index server applies periodic indexing of new texts, and the exploration server serves the...
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Báo cáo khoa học: Sensitivity to Hsp90-targeting drugs can arise with mutation to the Hsp90 chaperone, cochaperones and plasma membrane ATP binding cassette transporters of yeast docx
... investigating whether the expression of T101I and A587T mutant forms of Hsp82 influences the capacity of an Hsp90 inhibitor to activate the heat shock response In the absence of heat stress, a ... found these effects of the sti1D mutation on drug sensitivity to be influenced strongly by the isoform of Hsp90 that is expressed (at a similar level) in the cells Increased GA and RD sensitivity with ... photographed after days of growth at 30 °C on YPDA in the absence or presence of the indicated concentrations of GA or RD (B) RD and GA sensitivities of strains bearing deletions of the Pdr5 and...
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The preference of a Female Greek island population in regard to the gender of their gynecologist pdf
... 15-25% of the women consider the sex of the doctor to be an important factor in choosing their gynecologist.3,10,11 Furthermore, gender could make a significant difference in the type of services offered ... variables From the total of the examined variables, the ones that presented a significant statistic correlation with the choice of the sex of the gynecologist were identified The choice of the sex (malefemale) ... correlated with the choice of the sex Indeed, studies have attempted to reveal a connection between the demographic information of the respondents and their preference of the sex of their doctor It seems...
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Báo cáo hóa học: " Research Article A Generalized Approach to Linear Transform Approximations with Applications to the Discrete Cosine Transform" pptx
... is the approximation operator for the corresponding input xi , Dxi (Ti ) is the distortion due to the approximation Ti for the ith element of the input set (i.e., xi ), and d(·) is the distortion ... (17) If the approximation candidate sets (Φ1 , , ΦW ) and the input set X are given, Q, N, and W are fixed Then the metadata size is a linear function of the number of operating points K on the ... problem Let Q denote the cardinality of the given approximation candidate set Φ and let N the cardinality of the input set X Then the number of possible achievable C-D pairs is N Q Therefore, computational...
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Báo cáo hóa học: " Research Article Hop-Distance Estimation in Wireless Sensor Networks with Applications to Resources Allocation Liang Zhao and Qilian Liang" pot
... Communications and Networking point distribution is analogous to the 1D case, replacing the length of the segment by the area of the range Vural and Ekici reexamined the study under the sensor networks ... and kurtosis satisfy the Gaussianity condition within tolerance of error Furthermore, The postulated distribution and histogram are drawn together in Figures 2(a), 2(b), 2(c), and 2(d), which clearly ... examples, latency and energy estimation, in this section To emphasize the role of the number of hops in the estimation, we use general time and energy models On how to derive the parameters such...
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Báo cáo toán học: "Flattening Antichains with Respect to the Volume" doc
... < k and ≤ m ≤ p, the size of the new-shadow of the last m k-sets of Fk (p) is greater than or equal to 2m (ii) For ≤ p < n − k and ≤ m ≤ p, the size of the new-shade of the first m k-sets of Lk ... being the union of one of the singletons of [K] with the set {K + 2, , n} It is now easy to see that this collection is itself preceded by K+1 sets, each of them being the union of one of the ... that, if A is an antichain of size s and volume V , then there exists a flat antichain of size s and volume V Note that the result by Kleitman and Milner[5] and others is a special case of the...
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Báo cáo toán học: "A graph-theoretic method for choosing a spanning set for a finite-dimensional vector space, with applications to the Grossman-Larson-Wright module and the Jacobian conjecture" pdf
... and M(3, 4)5 = In the proof of Theorems 4.3 and 4.4 we refer to the diameter of an unrooted tree and the height of a rooted tree These are standard terms from graph theory The distance between two ... Equation 3.3 with Theorem 3.4 and the Gap Theorem, the link between the homogeneous symmetric reduction of the Jacobian conjecture and the Grossman-LarsonWright module is summarized as follows: Theorem ... in the reverse lexicographic ordering The crux of the proof is that there is a natural ordering of the mλ ’s and the eλ ’s in which the corresponding coefficient matrix is unitriangular Since the...
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Báo cáo y học: "Treatment of eccrine porocarcinoma with metastasis to the parotid gland using intensity-modulated radiation therapy: a case report" pptx
... lessons from clinical experience with the more common SCC of the head and neck The parotid gland is a common site for metastasis of cutaneous tumors of the scalp, frontotemporal and periauricular ... one year of therapy [17] In general, chemotherapy, if considered at all, is reserved for metastatic EPC On the other hand, the role of radiation therapy in EPC seems to have changed over the years ... and a scar at the previous frontotemporal lesion Figure Photomicrographs of surgical pathology specimens (AB) Photomicrograph of left parotid mass showing tumor cells of similar cytology to the...
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Báo cáo y học: "Typology of adults diagnosed with mental disorders based on socio-demographics and clinical and service use characteristic" pdf
... who were identified with mental or emotional problems were invited to indicate the services they used, type and frequency of utilisation, and degree of appropriateness of the service they used Services ... according to their overall contribution to inter-class homogeneity Results Description of the sample: predisposing, enabling and needs factors Among the 2,433 people who took part in the survey, ... all cases of mania, the greatest proportion of drug dependence, and the highest mean psychological distress score It ranked second with regard to the proportion of alcohol dependence and anxiety...
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Báo cáo y học: "TLR2 and TLR4 triggering exerts contrasting effects with regard to HIV-1 infection of human dendritic cells and subsequent virus transfer to CD4+ T cells" docx
... through the use of HEK-Blue™ IFNα/β cells according to the manufacturer's protocol (InvivoGen) These cells allow the detection of bioactive IFNα and IFNβ by monitoring the activation of the ISGF3 ... levels of HIV-1 receptor and coreceptors on the surface of DCs can affect virus entry, other factors can also modulate the life cycle of HIV-1 in DCs (e.g distribution of viral receptor/coreceptors ... membrane turnover and macropinocytosis [62] However the TLR 2and 4-mediated reduced expression of CD4 and CCR5 cannot explain the opposite effects of these two ligands with regard to HIV-1 replication...
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Báo cáo y học: " Enhanced macrophage tropism of HIV in brain and lymphoid tissues is associated with sensitivity to the broadly neutralizing CD4 binding site antibody b12" ppsx
... increases exposure of the b12 epitope and enhances macrophage tropism [10] To better understand the relationship between macrophage tropism and sensitivity to reagents targeting the CD4 binding ... to further examine the association between neutralization sensitivity to reagents targeting the CD4 binding site and macrophage tropism The capacity of HIV to enter macrophages correlated with ... mAb b6, or HIV-infected patient serum These findings suggest that exposure of the b12 epitope overlapping the CD4 binding site, rather than exposure of the CD4 binding site per se, enhances HIV...
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An action research on developing speaking skill throught oral presentations with reference to the coursebook Talk Time for the second year non-major students
... to study their own classrooms – for example their own teaching methods, their own students, their own assessment – in order to better understand them and be able to improve their quality or effectiveness ... of the topics in the coursebook They chose the group members at the first period of the course The teacher provided a list of topics for them to choose or they could choose their own topics ... believed that they needed to read a lot to widen their vocabulary and choose the easiest way of expressions for the classmates to understand One of them claimed “there are many new words in their oral...
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A study of correlative conjunctions as cohesive devices (with reference to the upper-secondary english textbooks)
... experience with them and on the basis of the situations in which these waves and forms are used Discourse analysis is concerned with the contexts in and the processes through which we use oral and written ... Cohesion and Coherence 14 2.3 Segmenting Texts into Units 16 2.3.1 Using the sentence as the unit of segmentation 16 2.3.2 Using the T-unit as the unit of segmentation 17 2.3.3 Using the proposition ... segmental units with reference to the Upper-secondary English textbook 1.3 Scope of the study: The study concerns the contrastive analysis of correlative conjunctions which are taught in the Upper-secondary...
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An effective trajectory based algorithm for ball detection and tracking with application to the analysis of broadcast sports video
... video is that of identifying the sport-specific events within the video These events are specific to and defined by the sports and are usually wellknown to both players and viewers of the sport For ... the image, (b) the small size of the ball relative to the image size, (c) occlusion of the ball (say, by players) in many images, and so on Because of these inherent difficulties associated with ... of candidate ball-like objects Then, in the second step, we use information of the path trajectories of these candidate objects over a short sequence of frames to obtain the ball (and prune off...
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A study on structural and semantic features of english idioms denoting anger with reference to the vietnamese equivalents
... out the study such as the rationale for selecting the topic, the aims, the objectives, the scope, the significance and the structure of the thesis Chapter - “Literature Review” - presents the ... had a profound style of writing, which revealed the reality of the society during 1930 – 1945 period Their characters in these works use a lot of idioms of anger to express their hatred to the corrupt ... Aims of the research 1.3 Objectives of the research 1.4 Scope of the research 1.5 Significance of the research 1.6 Structural organization of the thesis Chapter 2: LITERATURE REVIEW 2.1 Review of...
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A study on different types of verbal responses to questions in english conversations with reference to the vietnamese equivalents
... English and Vietnamese, bilingual samples, on the basis of their communicative meaning; the data was classified into groups on the basis of the presented forms for the realization of responses to ... can make the observance of the maxims or non-observance of the maxims as the following examples: Husband: Where are the car keys? Wife: They’re on the table in the hall The wife has ... discusses some different types of verbal responses to questions in English conversation to find out some similarities and differences on theory 1.5 SIGNIFICANCE OF THE STUDY Theoretically, the study...
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