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... effectiveness and cost. The capacity ofthe three ministries to implement the revised approach was then built at the provincial and district levels, the intervention expanded throughout the original two ... facilitate the process of “adapting and institutionalizing” the reproductive health and HIV activities within the three ministries at the district level initially, and to create conditions for their ... Heads of schools and chairpersons of School Management Committees MGSCSS: 72 Provincial and District level Ministry Officials MOH: 169 Ministry of Health staff public health officers at all levels...
... oxidation of the catalytic cysteine [14]. To test whether the move-ment ofthe P-loop in PhyAsr is due to oxidation of the catalytic cysteine, we oxidized crystals of PhyAsrTable 1. Effect of ionic ... anagreement with the Alberta Synchrotron Institute(ASI). The ALS is operated by the Department of Energy and supported by the National Institute of Health. Beamline 8.3.1 was funded by the NationalScience ... bondswith the P-loop main chain and Od1 and Od2.Although there are movements in the P-loop, thereare no other major conformational changes in the protein. Most notably, the loop containing the...
... hydrolysis wasconfirmed by the disappearance ofthe (Met1)-ONC(M23L) signal in the MALDI-TOF mass spectra 1 h after the addition of AAP. The pH was adjusted to 2.5, 8.0 and 11.5 andthe samples were incubated ... When evaluating the influence of Table 2. Thermodynamic parameters ofthe thermal denaturaturation ofthe different onconase (ONC) variants at 25 C and pH 2.0. (CGdm/HCl)ẵ13,midpoint of guanidinium ... foldsback against the N-terminal a-helix (a1) and forms ahydrogen bond with the CO group of Val96 in the C-terminal b-sheet. Pyr1 is also hydrogen bonded to the e-amino group ofthe Lys9 side-chain,...
... orshy (33% of females and 27% of males) and beingafraid (32% of females and 16% of males). Approximately 70% ofthe respondents had heardabout voluntary counseling and testing and while the majority ... further with their educa-tion. The other prevalent reasons for leaving schoolwere lack of interest, cited especially among the younger females; illness (17% of younger males and females); and ... or both of their bio-logical parents had died) (Table 3.3). About twice asmany respondents had lost their father (14%) than hadlost their mother (8% ofthe females and 7% of the males). Approximately...
... structures of EcR and USP from L. decemlineata (b) the analysis of mRNAexpression profile of L. decemlineata, EcR and USP, and (c) the measurement ofthe binding affinity of steroidal and nonsteroidal ... integument (INT) and whole body(WB) at day 4 in the last larval instar, in the INT at day 0, 2, 4, 6 and 8 in the last larvalinstar, and in the adult male WB (#), femaleWB ($), testis TES and ovary ... binding with PonA and a DBH analogBYI06830 [44]. We examined the conservation of these amino acid residues among several insects bycomparing the sequences ofthe ligand bindingdomain of EcRs (Fig....
... (the equivalent residue ofthe first cysteine ofthe CXXCHmotif of S. cerevisiae cytochrome c) overlays almostperfectly with the CH2group ofthe equivalent cyste-ine. Thus, the position ofthe ... 2831 ofthe alanine ofthe AXXCH motif (Ala25) (ingreen) andthe unsaturated vinyl group ofthe heme(cyan) are separated by 3.41 A˚(as compared with atypical thioether bond length of 1.8 ... called the C8vinyl), as is observed for the C-terminal cysteine of the typical CXXCH c-type cytochrome heme-bindingmotif [1,13]. The heme iron is coordinated by the Ne of the histidine of...
... constitutional law ofthe Community andthe analysis of the gaps between competition and free movement. Their actual scope, appropriatelevel of analysis and relationship with other parts ofthe legal ... commands, the law of one sovereignmust apply at the expense ofthe law ofthe other, and in the federal or transnationalunion, if the union and integration—are to be meaningful, it must be the ... in addition to those of the liberal age, are those of private economic power, the guarantee and reach of the social state and social rights, andthe globalisation of markets and politics.When...
... residing in the island of Manhattan, in the FortAmsterdam, under the government ofthe High and Mighty States-General ofthe United Netherlands and the West India Company, privileged by the Senate ... Bay with two ships, the Griffin andthe Key of Kalmar. From the Indians he bought large tracts of land in what is now the State of Delaware, and on the site ofthe present city of Wilmington he ... only pawns in the great game being played inEurope between Spain andthe Papacy on the one hand andthe Protestant countries, England, Sweden, and the United Netherlands on the other. Once apprehending...
... social, spiritual and moral well-being and physical and mental health. To thisend, States Parties shall: (a) Encourage the mass media to disseminate information and material of social and cultural ... dreams and their own local, social and ethnic culture and reality portrayed in the media.—Strengthened ability and curiosity, and increased media competence, i.e., their critical under-standing of ... information and material injurious to his or her well-being, bearing in mind the provisions of articles 13 and 18. Article 12 ofthe Convention on the Rights ofthe Child recognizes the right of the children...