... (17+,18+,19+,20+) for the reduced form, indicating a more open form of protein struc-ture for protonations upon disulfide-bonds reduction. Furthermore, the mol-ecular weight information obtained ... severalisoforms in addition to the target protein, as shown in its reversed-phaseAPPLICATIONS FOR BIOTECHNOLOGY PRODUCTS AND DRUG TARGETS 851 HPLC chromatogram (Figure 19 -6). Two of the three isoforms, ... cells. It not only interferes with foreign invaders that maycause infections, but also prevents the growth and spread of other diseased837 HPLC for Pharmaceutical Scientists, Edited by Yuri Kazakevich...