Báo cáo y học: " Induction and effector phase of allergic lung inflammation is independent of CCL21/CCL19 and LT-beta
Báo cáo y học: " Induction and effector phase of allergic lung inflammation is independent of CCL21/CCL19 and LT-beta
... initiation and effector phase of allergic lung inflammation is independent of LT and CCL21. Materials and Methods Mice LT knockout mice (LT-KO) backcrossed to C57BL/6 were kindly provided by Dr. S. ... in the absence of secondary lymphoid tissue (in LTα knockout mice [40]). Thus, allergic lung inflammation can be generated independently of organized secon-dary lymphoid tissue and the associated ... ooff MMeeddiiccaall SScciieenncceess 2009; 6(2):85-92 © Ivyspring International Publisher. All rights reserved Research Paper Induction and effector phase of allergic lung inflammation is independent...
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Tài liệu Báo cáo Y học: Induction of (2¢)5¢)oligoadenylate synthetase in the marine sponges Suberites domuncula and Geodia cydonium by the bacterial endotoxin lipopolysaccharide docx
... the (2–5)A pathway is also induced byinterferons [15]. The major enzyme in this pathway, the(2–5)A synthetase catalyzes the synthesis of a series of 2¢)5¢-linked oligoadenylates, termed (2–5)A ... by thin-layer chromatog-raphy, immunologically and by high-performance liquidchromatography. The biological activity of (2–5)A oligo-mers was verified by inhibition of the protein synthesis ... invading microorganisms is the (2¢)5¢)oligoadenylate synthetase [(2–5)A synthetase]system [11–13]. The (2–5)A synthetase(s) is activated bycertain classes of RNA, mainly double-stranded RNA [14].In...
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Báo cáo y học: "MALDI-TOF MS Combined With Magnetic Beads for Detecting Serum Protein Biomarkers and Establishment of Boosting Decision Tree Model for Diagnosis of Colorectal Cancer"
... examination of the colon remains to be the gold standard for diagno-sis, which is however invasive, unpleasant and carries associated risk of morbidity and mortality. Identifica-tion of high-risk ... biochemistry test. But, the sensitiv-ity and specificity of the current biomarkers in tumor diagnosis is low (usually less than 70%) and compli-cated by high return of ‘false-positives’ and ... specificity and sensitivity [30-34]. Matrix-assisted laser desorption/ionization time -of- flight mass spectrometry (MALDI-TOF MS) is one useful tool for integrating separation and analysis of complex...
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Báo cáo y học: "Grb2-associated binder 1 polymorphism was associated with the risk of Helicobactor pylori infection and gastric atrophy"
... study of the molecular mechanisms of action of this polymorphism. Because these results were based on the low frequency of A/A, they might be inconsistent due to the random errors. Studies of ... with the risk of Helicobactor pylori infection and gastric atrophy Yasuyuki Goto 1, Takafumi Ando 2, Kazuko Nishio 1, Sayo Kawai 1, Yoshiko Ishida 1, Mariko Naito 1, Hidemi Goto 2, Nobuyuki Hamajima ... Conclusions: This study represents that the Gab1 polymorphism was associated with the low risk of H. pylori infection and the high risk of gastric atrophy among seropositive healthy controls, and that seropositive...
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Báo cáo Y học: Baboon cytochrome P450 17a-hydroxylase/17,20-lyase (CYP17) Characterization of the adrenal microsomal and cloned enzymes docx
... 17-OHPROG.Understanding of the complexity of hydroxylase and lyase activity of CYP17 by way of primary sequencealignments of CYP17 from different species has limitations.Even though CYP17 homology ranges from 65 ... biosynthesis of aldosterone, cortisol and androgens. The 17a-hydroxylation of the D5-andD4-steroids, pregnenolone (PREG) and progesterone (PROG),yields 17a-hydroxypregnenolone (17-OHPREG) and 17a-hydroxyprogesterone ... diethylpyrocarbonate; DHEA, dehydro-epiandrosterone; DHEA-S, dehydroepiandrosterone-sulphate; DOC,deoxycorticosterone; CYP17, cytochrome P450 17a-hydroxylase;CYP21, cytochrome P450 21-hydroxylase;...
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Báo cáo Y học: Induction of chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI ) gene expression is mediated by ETS factor binding sites doc
... necessity for the accessory factors is likely due to poorDNA-binding af®nity of full-length Ets-1 rather than topoor potential of its activation domain. This is supported bythe existence (at ... af®nity even in theabsence of a ccessory factors. The auto-inhibitory domain is located within exon VII and a n alternative ly spliced form of Ets-1 t hat lacks this exon is constitutively ac ... Genbank accession number for this sequence is AY055471.Correspondence to S. Y. Tsai, Department of Molecular and CellularBiology, Baylor College of Medicine, One Baylor Plaza, Houston,Texas 77030,...
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Báo cáo Y học: Investigations into the mechanisms used by the C-terminal anchors of Escherichia coli penicillin-binding proteins 4, 5, 6 and 6b for membrane interaction ppt
... regions of dimyristoylglycerophosphoethanolamine and dimyristoylglycerophosphoglycerol membranes, P5appeared to show deep penetration of both these lattermembranes and dimyristoylglycerophosphocholine ... daphoenix@uclan.ac.ukAbbreviations:Myr2-PGro, dimyristoylglycerophosphoglycerol;Myr2-PCho, dimyristoylglycerophosphocholine; Myr2-PEtn,dimyristoylglycerophosphoethanolamine; FTIR, Fourier transforminfrared spectroscopy; ... (–) or in the presence of either: dimyristoylphosphatidylcholine (Myr2-PCho), dimyristoyl phosphatidylethanol-amine (Myr2-PEtn), or dimyristoyl phosphatidylglycerol (Myr2-PGro). For spectra...
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Báo cáo Y học: Conformationally constrained human calcitonin (hCt) analogues reveal a critical role of sequence 17–21 for the oligomerization state and bioactivity of hCt ppt
... Germany;2Rutgers University,Department of Chemistry and Chemical Biology, Piscataway, NJ, USACalcitonin (Ct) is a 32-residue peptide hormone that is mainly known for its hypocalcemic effect and ... acids and standard protection of the side-chains[Asp(OtBu), Glu(OtBu), G ln(Trt), Cys( Trt), H is( Trt),Lys(Boc), Tyr(tBu) and Thr(tBu)], with the exception of residues Lys21 and Asp17 of the cyclic ... N,N¢-diisopropylethylamine; DMS, dimethylsulfide; EDT,ethanedithiol; hCt, human calcitonin; MBHA, 4-methyl benzhydryl-amine resin; Mtt, 4-methyltrityl; Pip, 2-phenylisopropyl;OFm, fluoren-9-yl methylester; sCt, salmon...
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Báo cáo y học: "Electronic patient record use during ward rounds: a qualitative study of interaction between medical staff"
... period of 13 months: 1month prior to deployment of the EPR, 4 months after deploy-ment of the EPR, and 1 year after deployment of the EPR.Each time, six separate, randomly selected patient discussionswere ... pertinent details of the patient and any recentchanges. The discussion that ensues is led by the consultantworking systematically through a number of issues, as appro-priate. Any member of the ward-round ... todiscussion or may be specifically called on by the consultantfor their expertise. The ward round is usually close by the con-sultant asking &apos ;is there anything else?' Although there is...
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Báo cáo y học: " Laugh Yourself into a Healthier Person: A Cross Cultural Analysis of the Effects of Varying Levels of Laughter on Health"
... affluence and het-erogeneity of society. Most important to consider is “heterogeneity of society”. Mississauga is an ethni-cally diverse society where two or more cultures co-exist, this is considered ... Therefore, AUR and MISS were inde-pendently analyzed. Table 5: Cross cultural distributions of laughter and dis-ease patterns Level of laughter City Freq. of no disease Freq. of disease χ2 df ... “state of physical, mental and social well-being and not merely the absence of disease or bodily in-firmity,” and provided a holistic approach in assess-ing health. (21) An article by Richman J, offered...
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