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Báo cáo y học: "ntravenous transplantation of allogeneic bone marrow mesenchymal stem cells and its directional migration to the necrotic femoral head"

Báo cáo y học:

Báo cáo y học: "ntravenous transplantation of allogeneic bone marrow mesenchymal stem cells and its directional migration to the necrotic femoral head"

... study, we investigated the feasibility and safety of intravenous transplantation of al-logeneic bone marrow mesenchymal stem cells (MSCs) for femoral head repair, and observed the migration and ... transplanted the bone marrow stem cells into the necrotic femoral heads, and results show bone marrow stem cells can remove vascular lesions and promote angiogenesis in necrotic femoral heads, ... feasible and safe to treat femoral head necrosis by intravenous transplantation of allogeneic MSCs. Key words: femoral head necrosis; bone marrow mesenchymal stem cell; migration; safety Introduction...
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Báo cáo y học: " Low concentration of ethanol induce apoptosis in HepG2 cells: role of various signal transduction pathways"

... by a slight activation of the cell death receptor signaling pathway with increased phosphorylation of DAPK3 and DAPK1 equivalent to 56% and 38%, respectively. On the other hand, an anti-apoptotic ... inhibition of the JNK and the NFκB signaling pathway as demonstrated by a reduced phosphorylation of MEK4, IKKα, JNK and MEK6; with values of -36%, -33%, -27% and -26%, respectively. The pro-apoptotic ... ethanol inhibits the anti-apoptotic effect of the NFκB signaling pathway by reducing the phosphorylation of IKKα. Moreover, the increased expression of mRNA levels of NFκB after 6 hr of ethanol...
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Báo cáo y học:

Báo cáo y học: "Different effect of exercise on left ventricular diastolic time and interventricular dyssynchrony in heart failure patients with and without left bundle branch block"

... rest and during exer-cise by reducing LV dyssynchrony and thereby liber-ating a further segment of the RR interval for diastole (24). Considering that direct evaluation of LV dyssynchrony is ... closely re-lated to the phenomenon of mechanical dyssynchrony. These findings may further explain why patients with normal QRS duration may benefit from cardiac re-synchronization whether or not they ... defined as the time interval between the onset of the R-wave and the minimal volume on the time-activity curve (end-systole). The relative duration of left ventricular systole was derived as the product...
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Báo cáo Y học: Amidolytic activity of prostatic acid phosphatase on human semenogelins and semenogelin-derived synthetic substrates docx

Báo cáo Y học: Amidolytic activity of prostatic acid phosphatase on human semenogelins and semenogelin-derived synthetic substrates docx

... amidolytic activity was obtained by showing thatcommercial PAP hydrolysed the Abz-ISYQSSSTEEQ-EDDnp substrate at neutral pH, as does the puri®edenzyme. The ratio of the amidolytic activity of ... glutamine was the C-terminal residue of all peptides due to a requirement of the synthesis strategy [12]. All syntheses were performedwith Fmoc methodology using a multiple automatedpeptide synthesizer ... intramolecularly quenched¯uorogenic substrates. The system was standardized usingAbz-FR-OH prepared by total tryptic hydrolysis of Abz-FR-pNA, and its concentration was determined from the absorbance...
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Báo cáo Y học: Heterologous expression of a Rauvolfia cDNA encoding strictosidine glucosidase, a biosynthetic key to over 2000 monoterpenoid indole alkaloids pot

Báo cáo Y học: Heterologous expression of a Rauvolfia cDNA encoding strictosidine glucosidase, a biosynthetic key to over 2000 monoterpenoid indole alkaloids pot

... understanding the biosyn-thetic mechanisms. The next steps are to search for the participating genes and to clarify the regulation of productsynthesis, with the aim of influencing the biosynthesis ... for the C. roseus enzyme preparation. The reaction gives rise to the end product cathenamine and involves 4,21-dehydrocory-nantheine aldehyde as an intermediate. The enzymatichydrolysis of dolichantoside ... secologanin catalysed by the enzyme strictosidinesynthase (SS) [11]. The biosynthetic pathways leading to different classes of indole alkaloids branch off somewheredownstream of strictosidine. The first...
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Báo cáo Y học: Stimulated biosynthesis of flavins in Photobacterium phosphoreum IFO 13896 and the presence of complete rib operons in two species of luminous bacteria Sabu Kasai and Takumi Sumimoto pot

Báo cáo Y học: Stimulated biosynthesis of flavins in Photobacterium phosphoreum IFO 13896 and the presence of complete rib operons in two species of luminous bacteria Sabu Kasai and Takumi Sumimoto pot

... curve.Measurement of the total amount of flavins To obtain faster growth, the concentrations of polypeptone and yeast extract in the media used for this experiment wereincreasedto 5and2 .5gÆL)1, respectively. ... for M3, and 88% for M2. The growth rate of the parent strain culturedin 1% and 3% NaCl, was 67% and 33% of that of the threemutants, respectively. The maximum cell density of the parent cells ... prevail rapidly as if they grow faster and moredensely than the parent. The evidence above supports that the function of the lux operon is not to produce light, and light is a by-product of the bacterial...
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Báo cáo khoa học: Mechanistic investigation of a highly active phosphite dehydrogenase mutant and its application for NADPH regeneration pptx

Báo cáo khoa học: Mechanistic investigation of a highly active phosphite dehydrogenase mutant and its application for NADPH regeneration pptx

... PTDH and NAD is most likely due to the contributions of the hydrogen bonds between Glu175 and the 2¢- and 3¢-hydroxyl groups of the adenine ribose of NAD thatare lost in PTDH-E175A ⁄ A176R. The ... catalyzes the NADPH dependent conversion of xylose into xylitolwith very high catalytic efficiency. As xylitol produc-tion from xylose is commercially significant and haspreviously been coupled to ... may be greater than that of NADH regeneration. Currently, NADH-dependentenzymes are employed most frequently due to the expense of NADPH and the lack of a good regener-ation system. Hence the...
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Báo cáo Y học: Recombinant pronapin precursor produced in Pichia pastoris displays structural and immunologic equivalent properties to its mature product isolated from rapeseed pptx

Báo cáo Y học: Recombinant pronapin precursor produced in Pichia pastoris displays structural and immunologic equivalent properties to its mature product isolated from rapeseed pptx

... highcontent of cysteine residues. By means of the fusion of the pronapin with the secretion signal of the a-factor fromSaccharomyces cerevisiae and using a P. pastoris inducibleexpression system, ... degradation of the N-terminal end of rproBnIb resulted in a low yield(< 10%) of Gln. This behavior was identical to that of the protein obtained from the seeds and indicates the cyclation of the ... confirm the correct folding of the recombinant protein at the levels of secondary and tertiary structures.Immunological equivalence of rproBnIb and nBnIbIn order to quantify the IgG- and IgE-binding...
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Báo cáo y học:

Báo cáo y học: "A Comparison of Immuncapture Agglutination and ELISA Methods in Serological Diagnosis of Brucellosis"

... When they took the threshold value to be 1/320, they calculated these values to be 100 %, 59.1 %, 88.6 % and 100 % respectively. The Coombs test was taken as the reference test in our study, ... were similar to one another; in the follow-up of the treatment, the antibody titers determined via these tests were close to one another and it was concluded that they were well ... respectively (10). When the two ELISA Ig positivity were evaluated together, sensitivity and specificity were found to be 94.1 % and 97.1 % re-spectively. Evaluation of two Ig’s together...
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Báo cáo y học:

Báo cáo y học: "Surgical Treatment of Depressed Scar: A Simple Technique"

... satisfactory aspect of the scar due to the presence of an adhesion of the Ivyspring International Publisher Int. J. Med. Sci. 2011, 8 http://www.medsci.org 378 skin to the underlying plane, ... lines of closure are usually within or parallel to relaxed skin tension lines: lines due to dynamic action of the underlying mus-culature.1 The scar abnormality will guide the choice ... and are placed close to- gether so that a wide aversion is achieved at the mar-gins of the scar and a deep wound closure is obtained by adhering to the undermined tissue (Fig.4). These...
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