... amide and carbonyl of Cys140 form hydro-gen bonds with the backbone carbonyl and amide of Trp123, the side chain of which forms one wall of theactive site cavity and the replacement of which ... uncatalyzed dismutation of superoxide [32].A least-square fit of Eqn (1) to the data of Fig. 1yields the constants given in the legend of Fig. 1. Thevalues of kcat⁄ Km and kcatfor catalysis ... University of Illinois at Urbana-Champaign, Urbana, IL, USA2 Department of Pharmacology and Biochemistry, University of Florida, Gainesville, FL, USA3 Department of Neuroscience, University of Florida,...