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Efficacy of proton pump inhibitors in children with gastroesophageal reflux disease

Efficacy of proton pump inhibitors in children with gastroesophageal reflux disease

Efficacy of proton pump inhibitors in children with gastroesophageal reflux disease

... diagnosed in 12.3% of North American infants & in 1% of other pediatric age groups, with health care costs ~US $2386 /patient /6 months • Use of PPIs for the treatment of GERD in children has increased ... of PPIs in adults cannot be extrapolated to children It could be unethical to prescribe drugs without convincing evidence for efficacy of therapy in the age group to be treated 14 Drawbacks of ... • First: in infant RCTs (crossover design): Immediate withdrawal of PPIs may trigger a rebound effect of hypersecretion of gastric acid, thereby influencing study results • Second: in infant studies:...
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báo cáo hóa học:

báo cáo hóa học:" Psychometric validation of the Dutch translation of the quality of life in reflux and dyspepsia (QOLRAD) questionnaire in patients with gastroesophageal reflux disease" ppt

... Psychometric validation of the Italian translation of the gastrointestinal symptom-rating scale and quality of life in reflux and dyspepsia questionnaire in patients with gastro-oesophageal reflux ... [Psychometric validation of translation to Spanish of the gastrointestinal symptoms rating scale (GSRS) and quality of life in reflux and dyspepsia (QOLRAD) in patients with gastroesophageal reflux ... the psychometric validation of a Dutch translation of the QOLRAD questionnaire in patients with GERD Methods Patients Patients with GERD were selected in gastroenterology outpatient clinics Inclusion...
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Báo cáo y học:

Báo cáo y học: "The use of proton pump inhibitors for gastric acid suppression in critical illnes" pdf

... Prophylaxis for SRMD essentially involves either protecting the gastric mucosa or increasing the intragastric pH The principal means of directly protecting the gastric mucosa is the use of sucralfate ... Walter SD, Guyatt GH, Meade MO, Heyland DK, Kirby A, Tryba M: The attributable mortality and length of intensive care unit stay of clinically important gastrointestinal bleeding in critically ill patients ... Considerations for long-term use of protonpump inhibitors Am J Health Syst Pharm 1998, 55:2268-2279 61 Freston JW: Long-term acid control and proton pump inhibitors: interactions and safety issues in perspective...
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Is Lactobacillus GG Helpful in Children With Crohn’s Disease? Results of a Preliminary, Open-Label Study docx

Is Lactobacillus GG Helpful in Children With Crohn’s Disease? Results of a Preliminary, Open-Label Study docx

... PCDAI is a multi-item index including subjective reporting of abdominal pain, general well-being, and diarrhea and physical findings, including linear growth and laboratory parameters (hematocrit, ... Quantitative variables are described as medians with ranges in parentheses The significance of changes was evaluated us- ing analysis of variance (ANOVA) for parametric variables and the Mann–Whitney ... Prednisone, azathioprine Asacol, prednisone, azathioprine Azulfidine, metronidazole, prednisone, 6-mercaptopurine Pentasa, metronidazole, prednisone, azathioprine CD, Crohn’s disease; LGG, Lactobacillus...
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báo cáo hóa học:

báo cáo hóa học:" Double disadvantage: a case control study on health-related quality of life in children with sickle cell disease" potx

... Cite this article as: Hijmans et al.: Double disadvantage: a case control study on health-related quality of life in children with sickle cell disease Health and Quality of Life Outcomes 2010 ... double disadvantage: a chronic disease, on top of an unfavourable background Declaration of competing interests The authors declare that they have no competing interests Hijmans et al Health and Quality ... Emotional, social, and behavioral functioning of children with sickle cell disease and comparison peers Journal of Pediatric Hematology/Oncology 2004, 26:642-648 11 Panepinto JA: Health-related quality...
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Báo cáo y học:

Báo cáo y học: " ncremental cost effectiveness of proton pump inhibitors for the prevention of non-steroidal anti-inflammatory drug ulcers: a pharmacoeconomic analysis linked to a case-control study" potx

... treatments by medical specialists or drug therapy The costs for NSAID therapy and costs related to that therapy were not taken into account as these costs are expected to be similar in both treatment ... Arthritis Research & Therapy Vol 10 No Vonkeman et al with NSAIDs) with the appropriate pharmacoeconomic information Materials and methods The pharmacoeconomic evaluation was linked to a 26-month ... Chicago, IL, USA) Bootstrap analyses were performed using the software package S-plus (TIBCO Software Inc., Palo Alto, California, USA) professional version 6.0 Cost effectiveness To calculate the...
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Báo cáo y học:

Báo cáo y học: "Proton-pump inhibitors are associated with a reduced risk for bleeding and perforated gastroduodenal ulcers attributable to non-steroidal anti-inflammatory drugs: a nested case-control study" pptx

... drugs and nitrates on the risk of ulcer bleeding associated with nonsteroidal anti-inflammatory drugs, antiplatelet agents, and anticoagulants Am J Gastroenterol 2007, 102:507-515 Lanas A, Garcia-Rodriguez ... univariate analysis, cases and controls differ significantly with regard to body mass index, smoking habits, marital status, medical history of heart failure, myocardial infarction, stroke and ... the cases did not significantly change the results of the univariate or multivariate analyses Table Multivariate analysis of significant variables and other likely causational variables for serious...
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Báo cáo y học:

Báo cáo y học: "Incremental cost effectiveness of proton pump inhibitors for the prevention of non-steroidal anti-inflammatory drug ulcers: a pharmacoeconomic analysis linked to a case-control study" pptx

... treatments by medical specialists or drug therapy The costs for NSAID therapy and costs related to that therapy were not taken into account as these costs are expected to be similar in both treatment ... Arthritis Research & Therapy Vol 10 No Vonkeman et al with NSAIDs) with the appropriate pharmacoeconomic information Materials and methods The pharmacoeconomic evaluation was linked to a 26-month ... Chicago, IL, USA) Bootstrap analyses were performed using the software package S-plus (TIBCO Software Inc., Palo Alto, California, USA) professional version 6.0 Cost effectiveness To calculate the...
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Báo cáo y học:

Báo cáo y học: "Genetic polymorphism of ACE and the angiotensin II type1 receptor genes in children with chronic kidney disease" pps

... peptide angiotensin- II Its inhibition reduces the pace of progression of the majority of chronic nephropathies [13,14] Among the candidate genes of the RAS, the ACE, and angiotensin II type receptor ... determination via FAGG (N-[3-(2furyl) acryloyl]-L-phenylalanylglycylglycine) method (Biochemical enterprise) The ACE presented in the serum catalyzes the hydrolysis of the FAGG; forming furyl acryloyl ... through reducing the production of angiotensin II with ACEI or by blocking the action of angiotensin II at the AT1R receptor level with A II- type receptor blockers (ARBs), is particularly effective...
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Báo cáo y học:

Báo cáo y học: " Genetic polymorphism of ACE and the angiotensin II type1 receptor genes in children with chronic kidney disease" pot

... peptide angiotensin- II Its inhibition reduces the pace of progression of the majority of chronic nephropathies [13,14] Among the candidate genes of the RAS, the ACE, and angiotensin II type receptor ... determination via FAGG (N-[3-(2furyl) acryloyl]-L-phenylalanylglycylglycine) method (Biochemical enterprise) The ACE presented in the serum catalyzes the hydrolysis of the FAGG; forming furyl acryloyl ... through reducing the production of angiotensin II with ACEI or by blocking the action of angiotensin II at the AT1R receptor level with A II- type receptor blockers (ARBs), is particularly effective...
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Báo cáo y học:

Báo cáo y học: "Expression profiles of hydrophobic surfactant proteins in children with diffuse chronic lung disease" pptx

... histopathological findings, the BAL profile for SP-B, SP-C and their proforms appears use- ful in distinguishing PAP from SP-B deficiency of any etiology Children with chronic respiratory distress of unknown ... major findings are the presence of mature SP-B and SP-C in all children, except those with SP-B deficiency, supporting the view that analysis of BAL for these surfactant proteins may aid in the ... Guttentag S, Schauer-Vukasinovic V, Derrick M, et al.: Involvement of napsin A in the C- and N-terminal processing of surfactant protein B in type-II pneumocytes of the human lung J Biol Chem 2003,...
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Báo cáo y học:

Báo cáo y học: "Correlates of self-reported offending in children with a first police contact from distinct sociodemographic and ethnic groups" pot

... level of offending among children who have already committed an offense Focusing on offending in younger children, defined as committing a first offense before puberty, may bear specific relevance, ... factors independently correlated with level of offending Contrary to our Page 10 of 12 hypothesis, family or parenting characteristics did not correlate independently with level of offending in ... Netherlands Journal of Child Psychology and Psychiatry 2003, 44:412-423 20 Sampson RJ, Morenoff JD, Raudenbush SW: Social anatomy of racial and ethnic disparities in violence American Journal of...
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Tài liệu Nutrition in Children with Chronic Kidney Disease pptx

Tài liệu Nutrition in Children with Chronic Kidney Disease pptx

... sheets: I Nutrition for Early Chronic Kidney Disease in Adults I Nutrition for Later Chronic Kidney Disease in Adults I Nutrition in Children with Chronic Kidney Disease For free single printed copies ... does not mean or Nutrition for Later Chronic Kidney imply that the Adults is unsatisfactory Disease in product I Nutrition in Children with Chronic Kidney Disease For free single printed copies of ... contact the National KidneyAbout the Nutrition for and Urologic Diseases Information Clearinghouse Chronic Kidney Disease Series The NIDDK Nutrition for Chronic Kidney Disease Series includes three...
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Tài liệu Sport and Physical Activity in Children with Congenital Heart Disease ppt

Tài liệu Sport and Physical Activity in Children with Congenital Heart Disease ppt

... surgery/interventions (including ablations) Group Patients after cardiac surgery/interventions (including ablations) 1.1 Without remaining findings (complete correction) 1.2 With minimal findings ... B Mild (remaining) findings 1.2; 2.1; 2.2; 2.3; 2.4; 4.2 Unlimited C Clinically significant (remaining findings) 1.3; 5.1; 5.2; 5.3 No competitive sports D Severe (remaining) findings 1.4a; 1.4b; ... recommendations on types of sport suitable for all persons with congenital heart disease (e1, 8, e5, 9, 11, 12, 13, e8, e9, 17) Physical activity in children with congenital heart disease should start...
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báo cáo khoa học:

báo cáo khoa học: " A randomized trial to assess the impact of opinion leader endorsed evidence summaries on the use of secondary prevention strategies in patients with coronary artery disease: the ESP-CAD trial protocol" doc

... cardiovascular; Atorva = atorvastatin; Prava = Pravastatin; Simva = simvastatin the EURopean trial On Reduction of cardiac events with Perindopril in stable coronary Artery disease (EUROPA)[34] and the ... with statin use (ALLHAT-LLT) was likely contaminated by very high rates of statin use in the "control" arm of that trial[ 15] A meta-analysis of these trials confirmed that statins are clearly beneficial ... MI, and treatment of unstable angina) A tenth trial evaluated the impact of a multifaceted intervention that included physician and nurse opinion leaders (as two of the 10 factors included in the...
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