... trial of a treatment, patients are asked whether they are willing to consent to randomization to the treatment or control, and willing to participate in all other aspects of a trial, such as ... social, scientific, and financial costs of seeking consent are demonstrated by the hospital-based study in Canada that spent a quarter of the budget to achieve only 50.6% participation in a disease ... potential healthcare professionals may make the project unfeasible or bias our assessment of the study outcome As a result, we informed all general practitioners within the study areas that there was...