scientific and regulatory issues in development of chiral drugs
Báo cáo y học: " Importance of cumulative exposure to elevated cholesterol and blood pressure in development of atherosclerotic coronary artery disease in systemic lupus erythematosus: a prospective proof-of-concept cohort study" pdf
... include methotrexate, azathioprine, chloroquine and hydroxychloroquine; defined as used ever during the study in time-constant models, and coincident with each TC (or constant models, and coincident ... in plasma using a commercial assay (Boehringer Mannheim kit 236691 Indianapolis, IN) and recorded in mmol/L As there are only small, clinically insignificant differences in TC when measured in ... hypercholesterolemia and hypertension account for only a small proportion of the increased risk of CAD in SLE However, in these studies TC and BP were measured at baseline, in keeping with the premise of the...
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analyse the importance and impacts of corporate social responsibility (csr) in business towards the social and environmental issues in vietnam
... entertainment of humans With people’s living standards are improving and increasing industrialization and development of more extensive and garbage are making more and more with the increasingly ... better understanding of CSR and they can avoid violating any issues related to CSR The second goal of this project is to evaluate the impact of CSR in the environmental issues in companies in Vietnam ... quality and delivery in business Integrate CSR into business strategy and become the conditions required for business survival and development CSR describes the principle that companies can and should...
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Báo cáo khoa học: Mechanism for transcriptional synergy between interferon regulatory factor (IRF)-3 and IRF-7 in activation of the interferon-b gene promoter docx
... The intensity of binding, expressed as percentage of input bound, is indicated by different shades of gray and only interactions resulting in binding to more than 1.5% of input are shown IRF-3 and ... Mapping of domains of hp300/mCBP interacting with transcription factors Summary of interaction studies between domains of the p300 and CBP coactivators and the transcription factors that can bind ... c-Jun for the N- and C-terminal regions and of ATF-2 for the central region of the coactivators Binding of p50 (amino acids 1–503 of p105) to GST– p300/CBP was very weak overall Binding to CBP–N...
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Cooperation programs and agricultural rural developmen:Development of clam culture for improvement and diversification of livelihoods of the poor coastal communities in Central Vietnam - MS10 " pot
... Salinity shock: increasing salinity of water up to 32ppt by using sea water in 30 minutes and reducing to 15ppt by fresh water in 30 minutes later This method could be repeated times, if spawning ... such as stocking density and salinity are within the capabilities of smallholder end-users to monitor and manipulate By focusing upon the research and understanding of the impact of such factors ... season and how to increase frequency of spat production 14 Breeding / Spawning Breeding / Spawning Inducement Factors • Enable regional hatcheries to know what factors induce breeding and spawning,...
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Báo cáo y học: "Smoking and nicotine exposure delay development of collagen-induced arthritis in mice" pptx
... recognition in regulation of inflammation Van Maanen and colleagues has recently shown that the use of nicotine and an agonist of the nicotinic acetylcholine receptor subunit α7 reduced severity of clinical ... arthritis and were indistinguishable from the controls, and this pattern remained until the end of the experiment All mice, including controls, experienced a decrease in body weight during the development ... Effect of nicotine on collagen induced arthritis In the second set of experiments, nicotine (100 μg/ml, concentration 0.01%) was provided in the drinking water during the entire course of the...
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some solutions to improve and enhance the sustainable development of the securities market in viet nam
... Improving and promoting the sustainable development of the securities market in Viet Nam INTRODUCTION To implement the industrialization and modernization of the country, maintain the pace of sustainable ... of consulting services • Investment Advisory of buying and selling securities • Consulting portfolio management • Advising information on securities activities Purpose Promoting investors in ... standards of the market and the best international practices as well as in line with actual conditions and socio-economic development orientation and positively take the initiative in integrating...
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Multi-beneficial for mitigation of climate change in Vietnam and Indochina countries by development of biomass energy project
... Sustainable Development (SATREPS) MULTI-BENEFICIAL FOR MITIGATION OF CLIMATE CHANGE IN VIETNAM AND INDOCHINA COUNTRIES BY DEVELOPMENT OF BIOMASS ENERGY PROJECT The 1st Joint Coordinating Com m ... Root, le a f and stem fresh w e ig h t of Jatropha plant cultured in vitro in L and 60 L ve sse ls on day 55 Root, le a f and stem dry w e ig h t of Jatropha plant cultured in vitro in L and 60 L ... fresh w e ig h t and root length of Jatropha plant cultured in vitro at day 42 Table Effect of supporting material on leaf area and increase dry weight of Jatropha plant culture in vitro on day...
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The role of cholesterol sequestration and accumulation in the endocytic pathway in development of neurodegenerative diseases
... 2002) Cholesterol in the brain may play an important role in synaptic development and plasticity, brain growth, neuron repair and remodeling, and even maintaining the normal function of this important ... cleave a variety of intracellular polypeptides, including major structural elements of the cytoplasm and nucleus, components of the DNA repair machinery, and a number of protein kinases, which then ... orthologs and is referred to as the NPC1 domain Within NPC1 there is a large, cysteine-rich luminal loop (amino acids 855–1098), which contains a ring-finger motif that may mediate protein– protein interactions...
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Courts and Regulatory Governance in Latin America Improving Delivery in Development by Managing Institutional Interplay
... the poorest Instead of focusing on IRAs as stand-alone units and on the ways that things should be done, scholars could think in terms of interaction and how it triggers learning and experimentation ... taken place in the context of rule of law programs concerned with reducing court backlogs, enhancing judicial training programs, and eliminating judicial corruption The Regulatory State in the South ... services in the region Why courts get involved in the regulatory process in Latin America? How is this involvement undertaken? What are the effects of courts’ involvement in the regulatory process in...
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Summary of financial and banking phd thesis Development of commercial banks noncredit services in Vietnam
... serving more customers Online banking service development: In line with the continuous development of information technology and telecommunication, in response to increasing customer needs, online ... OVERVIEW OF BANKING SERVICES 1.1.1 Definition Banking services are banking operations providing customers services as required including deposit saving, lending, payment and foreign exchange trading, ... number of Vietnam commercial banks is 40 Vietnam banking system is continuously expanded and diversified in terms of scale, ownership and business However, the weakness of the Vietnam banking system...
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The relationship between the industry competitiveness and factors supporting the development of cluster Case study of the cluster of the digital content industry in Vietnam
... production and business activities CL_DHCN4: High degree in applying and improving continuously new technologies in business operating in the activities of DCI production and service in Vietnam ... structure of samples including all business operating in all industries in Vietnam and the Clusters of other industries; (2) the collection of information was made from research materials such as scientific ... consideration and approval of DCI as a key economic industry in the year 2007, which was the year of the creation of “Vietnam Institute of Software and DCI as a landmark to initiate many “studies of matters”...
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Tài liệu Báo cáo khoa học: The role of the SEA (sea urchin sperm protein, enterokinase and agrin) module in cleavage of membrane-tethered mucins pdf
... leucine and valine residues N-terminal to the MUC3 and MUC12 specific sequences and a serine residue C-terminal to them Transient expression of epitope-tagged mucin proteins in Cos-7 cells and ... modules of MUC1 and MUC16 and the shortening of the predicted loop in MUC1 (FRPGSV_ _ _VV in MUC1 compared to FRSVSNNNNHT in MUC16) makes detailed structural analysis of specific interactions within ... according to the intensity of M2-reactive species in the corresponding whole cell lysate Molecular modeling of SEA domain of MUC1 The composer and biopolymer modules of the sybyl 6.91 software package...
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Báo cáo khoa học: "Methods and Practical Issues in Evaluating Alignment Techniques" doc
... section of the C Series of the Official Journal of the European Community in all of its official languages This corpus, which was collected and prepared during the MLCC and MULTEXT projects, contains, ... were not taken into account in the final grading of the systems The overall ranking for all systems (excluding the T E C H corpus results) is given in Figure 2, in terms of the Sent and Char F-measures ... diversity in the nature of the texts was preferred to the collection of a large quantity of similar data 3.1 F o r m a t ARCADE contributed to the development and testing of the Corpus Encoding Standard...
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Ethical, Legal, and Social Issues in Medical Informatics pot
... pioneering work of Ed Hammond and his interest in community and family medicine Very soon, the European Union will be celebrating a 20-year history of co-financing eHealth research and development initiatives ... to accessing, understanding, regulating, and distinguishing the valid from the invalid are not trivial However, whilst some of the issues are challenging they are not xi insurmountable and great ... online questionnaire takes no account of the level of literacy of the patient—either in terms of understanding the terminology used in the context of health, competence in the language used in...
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Measuring the Statutory and Regulatory Constraints on Department of Defense Acquisition - An Empirical Analysis doc
... effects of changes in funding, schedule, or quantity; and • completing “other” activities related to programming and budgeting • • • • 26 Measuring the Statutory and Regulatory Constraints on ... personnel, and Office of the Secretary of Defense and industry officials who gave their time and insights in support of this research Special thanks are due to the program managers and staff of the seven ... Benefits include providing mechanisms for oversight and accountability, preserving information on program status and decision making, and formalizing decision processes, among others In the set of...
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Child-friendly health care: the views and experiences of children and young people in Council of Europe member States doc
... setting and what could make it more child-friendly, the attitudes and behaviours of health care professionals and issues affecting communication and children’s use of health care services Accordingly, ... experiences of health care in certain parts of the Council of Europe For this reason, a Council of Europe consultation was planned, chiefly by means of a survey, with a view to recording the views of ... children in its legal and policymaking work Children and young people have a right to have their voices heard and taken into account in matters that affect them in accordance with Article 12 of the...
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Measuring the Statutory and Regulatory Constraints on Department of Defense Acquisition - An Empirical Analysis pptx
... effects of changes in funding, schedule, or quantity; and • completing “other” activities related to programming and budgeting • • • • 26 Measuring the Statutory and Regulatory Constraints on ... personnel, and Office of the Secretary of Defense and industry officials who gave their time and insights in support of this research Special thanks are due to the program managers and staff of the seven ... Benefits include providing mechanisms for oversight and accountability, preserving information on program status and decision making, and formalizing decision processes, among others In the set of...
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Báo cáo khoa học: Subcellular localization of yeast Sec14 homologues and their involvement in regulation of phospholipid turnover pptx
... integrative versions of C-terminal yEGFP fusions in frame with the ORF of interest Thus, yEGFP fusions were present in single copy in the genome and driven by the native promoter of the ORF of ... formation, indicating that Sec14p and the two homologues act as inhibitors of Plb1p in vivo This observation explains at least in part the low Plb1p activity in wild-type cells Interestingly, the inhibitory ... sites of action of these polypeptides, C-terminal fusions of Sfh-proteins with yEGFP were constructed and the localization of the proteins in the yeast cell was determined The enzyme catalyzing...
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unsicker - cell signaling and growth factors in development
... organization and function of cadherins b-Catenin binds to the cytoplasmic domain of type I cadherins, linking cadherins through a-catenin to the actin cytoskeleton [24, 26, 27] 1.2.2 Wnt Signaling Regulates ... stabilized b-catenin and lack of APC in ESCs results in the inhibition of neural differentiation and in activation of downstream targets of Wnt signaling such as cyclins, c-myc and BMP [35, 36] ... Hindbrain: the Role of Auto- and Cross-regulation 204 A Mechanism for Establishing and Maintaining Hindbrain Segmentation 206 Coupling Cell Lineage Restriction with Discrete Domains of Hox Gene Expression...
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virtue norms and objectivity issues in ancient and modern ethics may 2005
... raising original questions and offering searching and sustained analyses of salient issues in this connection This volume is subdivided into two parts In the first part, Issues in Ancient and ... Outline of the Volume Issues in Ancient and Modern Theory: The Nature and Grounding of Ethical Norms There are two main issues in the first part of the volume One is that of the overall shape of ... The most profound insights of the three areas are mutually informing in a way that bears on the understanding of key concepts in any one area.25 Hence, for instance, the understanding of what ‘good’...
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Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ các đặc tính của động cơ điện không đồng bộ đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng 9 tr 25