Design of protein linkers for the controlled assembly of nanoparticles

... DESIGN OF PROTEIN LINKERS FOR THE CONTROLLED ASSEMBLY OF NANOPARTICLES CHEN HAIBIN (B ENG, XI’AN JIAOTONG UNIVERSITY, P R CHINA) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY ... protein forms, was investigated Chapter 1.3 Outline of the thesis This thesis is composed of eight chapters Chapter describes the motivation and defines the objectives and scope of the work The ... with the aid of AFM image analysis of the phage particles bound on the surface Chapter of the two metal oxides, elucidated whether the nature of phage (or the displayed peptide) binding to the...

báo cáo khoa học:"The WRITTEN-HEART study (expressive writing for heart healing): rationale and design of a randomized controlled clinical trial of expressive writing in coronary patients referred to residential cardiac rehabilitation" docx

... meet inclusion criteria of having had a medical diagnosis of Coronary Heart Disease (CHD) and being affected by major cardiovascular risk factors will be asked and screened for admission in the study ... Such appealing features have made it very attractive for some clinicians and clinical researchers who, beginning in the 90s and going on until nowadays, have started to use the expressive writing ... highland and far away from towns and cities Few days after entry in the CR unit and immediately after the initial medical evaluation and treatment planning (first week), patients will be approached...

Tài liệu Novel Design of an Integrated Pulp Mill Biorefinery for the Production of Biofuels for Transportation pot

... paper mill, there is a large steam and electricity demand at the pulp mill To simplify calculations, we decided to use only a pulp mill rather than an integrated pulp and paper mill As a result, the ... From the calculations derived in Appendix A, the energy demand for the modified pulping section of the plant is 56 MW of electricity and 267 tonnes per day of steam The demand for the steam in the ... the pulp mill will require a steam demand listed in the tables below The pulp mill found in the papers does not exist because the pulp mill plant cannot economically upgrade their plant with the...

Báo cáo khoa học: Identiﬁcation of the structural determinant responsible for the phosphorylation of G-protein activated potassium channel 1 by cAMP-dependent protein kinase pdf

... identify the structural determinants that are responsible for phosphorylation of GIRK1 by PKA, fusion proteins comprising truncated forms of the cytosolic parts of GIRK1 and the glutathione S-transferase ... GIRK1F137S) currents had been described previously [18 ] To assess the role of the S ⁄ Ts in the regulation of GIRK1 via PKA in a manner that is unbiased by the eventual contributions of the other ... GIRK1 and GIRK2 subunits of the G protein -activated K+ channel J Biol Chem 278, 2 917 4–2 918 3 Kennelly PJ & Krebs EG (19 91) Consensus sequences as substrate-speciﬁcity determinants for protein- kinases...

Báo cáo khoa học: YidC is required for the assembly of the MscL homopentameric pore potx

... equal to that of the non-depleted IMVs This indicates that YidC is required for assembly of the MscL complex (Fig 5) To investigate the role of the Sec translocon in formation of the MscL HA complex, ... of YidC had no major effect on the insertion of MscL, but formation of the pentamer was almost completely abolished under these conditions, suggest4892 ing a novel role for YidC in assembly of ... depletion of SecE did not have a signiﬁcant impact on the level of the MscL HA complex, suggesting that the Sec translocon is dispensable for the oligomerization of the MscL subunits Discussion...

Báo cáo khoa học: Investigations into the ability of an oblique a-helical template to provide the basis for design of an antimicrobial anionic amphiphilic peptide pot

... contribute to the susceptibility of E coli model membranes to the action of AP1 An important determinant of the susceptibility of membranes to a-AMPs is the packing characteristics of the individual ... hypothesis of Tytler et al [48], it may be that insertion of the inverted wedge shape formed by the AP1 a-helix into membranes of E coli leads to the formation of nonbilayer structures and thereby ... FEBS S R Dennison et al Antimicrobial properties of an anionic a-helical peptide Fig A pressurearea isotherm for an AP1 monolayer The peptide was spread from chloroform on to a Tris HCl buffer...

Báo cáo khoa học: NMR and molecular dynamics studies of an autoimmune myelin basic protein peptide and its antagonist Structural implications for the MHC II (I-Au)–peptide complex from docking calculations ppt

... various systems comprised 3899 and 4516 SPC molecules for the agonist and the antagonist in water, respectively, and 817 and 927 Me2SO molecules for the agonist and the antagonist, respectively, corresponding ... the binding and afﬁnity for I-Au because of occupation of the P1 pocket Recent thermodynamic and kinetic studies of the binding of TCRs to peptide MHC ligands suggested that the low afﬁnity of ... (1999) Design and synthesis of a potent cyclic analogue of the myelin basic protein epitope MBP72-85: importance of the Ala81 carboxyl group and of a cyclic conformation for induction of experimental...

Báo cáo khoa học: Two short protein domains are responsible for the nuclear localization of the mouse spermine oxidase l isoform pdf

... nuclear localization for the mSMOl isoform (Fig 4) Taken together, these results consistently substantiate the hypothesis that these two structural regions are mandatory for the nuclear localization ... v) paraformaldehyde in NaCl ⁄ Pi (15 at °C) to evaluate the subcellular localization of the various isoforms Determination of the subcellular localization of mSMOa, -l and -lD ⁄ V5tagged proteins ... Bianchi et al Protein domains involved in mSMOl targeting to the nucleus Fig Subcellular localization of the mouse spermine oxidase catalytically active splice variants mSMOa, mSMOl and mSMOlD in transiently...

Báo cáo khoa học: The 3¢-UTR of the mRNA coding for the major protein kinase C substrate MARCKS contains a novel CU-rich element interacting with the mRNA stabilizing factors HuD and HuR ppt

... 5¢-CCC CGG GCC CGA ATT CCT TTC TTT CTT TCT TTC TTT CTT TCT TTC TTT CTT TCT TTC TTT TTT TTT TTC TCG AGC CCC-3¢; antisense: 5¢-GGG GCT CGA GAA AAA AAA AAA GAA AGA AAG AAA GAA AGA AAG AAA GAA AGA AAG ... luciferase -MARCKS construct and for transient transfection with the cDNAs coding for human HuD and HuR The mouse embryonic carcinoma cell line PCC7-Mz1 is a subclone of the PCC7-S-AzaR1 (clone 1009) cell ... mRNA (A) The MARCKS 3¢-UTR, the stop codon UAA of the coding sequence (CDS) and the poly (A) sequence are depicted The box within the 3¢-UTR marked the identiﬁed CU-rich sequence interacting with...

Báo cáo khoa học: "THE DESIGN OF THE KERNEL ARCHITECTURE FOR THE EUROTRA* SOFTWARE" pptx

... 1982) The elements of the vocabulary of a control language are names of PSs, and the well-formed strings of the language define just those sequences of PS applications which are allowed The user ... It follows that the generator must provide compilations of these defintions in the language of the kernel machine The implementation of the control generator is an adaptation of B a d e n ' s ... know of no language as suitable for the description of data as FP for the description of control The reason is that at this moment, we are insufficiently confident of the basic character of data...

Báo cáo khoa học: Interaction of Sesbania mosaic virus movement protein with the coat protein – implications for viral spread Soumya Roy Chowdhury and Handanahal Subbarao Savithri docx

... similarity with MPs of viruses from other genera Within sobemoviruses, the sequence of the SeMV MP was closest to that of the SBMV-Ark MP (32% sequence identity), and the identity with MPs of other ... Alfalfa mosaic virus Cucumber mosaic virus Cowpea mosaic virus Brome mosaic virus Tobamovirus Alfamovirus Cucumovirus Comovirus Bromovirus Percentage identity with SeMV Percentage similarity with ... function of the pH of the FEBS Journal 278 (2011) 25 7–2 72 ª 2010 The Authors Journal compilation ª 2010 FEBS 261 Interaction of SeMV MP with viral coat protein A B C S R Chowdhury and H S Savithri...

Báo cáo khoa học: Differential tissue-speciﬁc distribution of transcripts for the duplicated fatty acid-binding protein 10 (fabp10) genes in embryos, larvae and adult zebraﬁsh (Danio rerio) docx

... show differential tissue-specific distribution of fabp10a and fabp10b transcripts in developing and adult zebrafish, evidence of the divergence of regulatory elements in the promoters of the fabp10a ... vesicles indicates a potential role for this protein in the early development of the zebrafish brain Tissue-specific distribution of fabp10b gene transcripts in adult zebrafish The tissue-specific distribution ... transcripts in embryos, larvae and adult zebrafish show strikingly different tissue-specific patterns of distribution On the basis of the distribution of fabp10b transcripts in many tissues of adult zebrafish, ...

Báo cáo khoa học: Kinetic mechanism for p38 MAP kinase a A partial rapid-equilibrium random-order ternary-complex mechanism for the phosphorylation of a protein substrate potx

... EÆMgATP complex is not a deadend complex with respect to the binding and phos4633 Kinetic mechanism for p38 MAP kinase a A E Szafranska and K N Dalby Fig Preparation of activated p38 MAPKa and ATF2D115 ... propose, therefore, that the kinetic mechanism for p38 MAPKa should be reassigned as a partial rapidequilibrium random-order ternary-complex mechanism for the phosphorylation of ATF2D115 FEBS Journal ... Szafranska and K N Dalby Kinetic mechanism for p38 MAP kinase a mechanism We also show that nucleotides such as MgATP and particularly magnesium ADP (MgADP) bind preferentially to the binary p38 MAPKa–...

Báo cáo Y học: Monitoring the structural consequences of Phe12 ﬁ D-Phe and Leu15 ﬁ Aib substitution in human/rat corticotropin releasing hormone Implications for design of CRH antagonists pdf

... Glu39 in 40 out Ó FEBS 2002 of 40 DYANA models) further support the continuous C-terminal helix structure Monitoring the Phe12 fi D-Phe and Leu15 fi Aib substitution The NOE pattern of the CRH analogue ... Arg16 and Glu20 The biological impact of the Aib1 5 and D -Phe12 modifications on the synthetic CRH analogue is illustrated by the peptide binding affinity enhancement towards the CRH receptor and ... for the final family is given in Fig S1 Fig 3A shows the family of 40 structures and Table contains a summary of statistical data indicating the quality of the 40 models and the average energyminimized...

Xem thêm

Từ khóa: moiré pattern as a template for the self assembly of c60 molecules structural design standards and codes for the offshore industry two scene 2 in which the design will also change for the better matlab as a design and verification tool for the hardware prototyping ofwireless communication s the evolution of screw design technology for the injection molding process mobile adhoc routing protocols survey for the design of vanet applications mobile ad hoc routing protocols survey for the design of vanet applications process design for the production of ethanol from ethylene code of practice for the design construction operation management discuss the need for evaluation of training how can evaluation help the design of training programs cumulative specificity a universal mechanism for the initiation of protein synthesis 3a program and project management for the acquisition of capital assets and doe m 413 3 1 project management for the acquisition of capital assets and doe std 1189 2008 integration of safety into the design process implication for the design of virtual reality simulators a framework for the design of web service based clinical management systems to support inter and intra organizational patient journeys lipid involvement in viral infections present and future perspectives for the design of antivir Báo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018 Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thống Báo cáo quy trình mua hàng CT CP Công Nghệ NPV chuyên đề điện xoay chiều theo dạng Một số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTP Biện pháp quản lý hoạt động dạy hát xoan trong trường trung học cơ sở huyện lâm thao, phú thọ ĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDE Quản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninh Trả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Nghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chế Thơ nôm tứ tuyệt trào phúng hồ xuân hương Thiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khí Kiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vật chuong 1 tong quan quan tri rui ro Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vật Chiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015 Đổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt nam