Development of database and computational methods for disease detection and drug discovery
Development of database and computational methods for disease detection and drug discovery
... conventional and molecular detection methods of pathogen; (2) bioinformatics and cheminformatics in drug discovery; (3) database development; (4) virtual screening of drug discovery; (5) objectives and ... efficient and effective To help achieve this purpose, this work on "Development of Database and Computational Methods for Disease Detection and Drug Discovery" is conducted as one of the strategies ... comprehensive information about the primary targets and drug of the approved, clinical trial, and experimental drugs These database lead to a better understanding of the disease and benefit for drug discovery...
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Development of self assembly templating methods for architecture of porous core shell nanocomposites
... DEVELOPMENT OF SELF- ASSEMBLY TEMPLATING METHODS FOR ARCHITECTURE OF POROUS CORE- SHELL NANOCOMPOSITES WANG DANPING (B.Sc, Xi’an Jiaotong University, China) A THESIS SUBMITTED FOR THE DEGREE OF ... growth of core- shell nanocomposites with unique structures Figure 2-13 TEM images of (a) self- assembled Ni@SiO2 core- shell nano-necklace, Ni@SiO2 yolk -shell nano-necklace with diameters of (b) ... hollow SiO2 shells Figure 2-13 exemplifies that linear assembly of Ni nanoparticles induced by magnetic interaction can template for the formation of Ni@SiO2 core- shell and yolk -shell nanocomposites. 88...
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Development of some local search methods for solving the vehicle routing problem
... DEVELOPMENT OF SOME LOCAL SEARCH METHODS FOR SOLVING THE VEHICLE ROUTING PROBLEM ZENG LING (B.ENG, DUT) A THESIS SUBMITTED FOR THE DEGREE OF MASTER OF ENGINEERING DEPARTMENT OF INDUSTRIAL ... traversed by the vehicle; • The costs associated with the utilization of the vehicle; • The capacity of the vehicle, expressed as the maximum weight or volume the vehicle can load; • The devices ... studied type of the VRP family Set covering based algorithms One of the exact methods for solving the VRP is based on a set covering formulation of the problem Let the index set of all feasible...
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Báo cáo y học: "Distribution patterns of small-molecule ligands in the protein universe and implications for origin of life and drug discovery" doc
... independently of proteins [56-59], the binding of ligands with primordial proteins would also be a critical step in the origin of life Thus, it is intriguing to explore the chronology of ligand -protein ... energy release during ligand binding may meet the free energy demand during protein folding It is tempting to examine the conjecture of ligand-induced formation and/ or folding of primordial proteins ... events in the origin of life and as well as for understanding the new paradigms in drug discovery Results Distribution patterns of ligands in the protein universe Although considerable efforts...
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development of novel micro-embossing methods and microfluidic designs for biomedical applications
... devices for BioMEMS applications The emphasis is on the development of new hot embossing techniques, the design of microfluidic functions and biocompatible packaging methods for polymeric microfluidic ... design and implementation of necessary microfluidic functions; integration of these functions with complete automation; and development of cost-effective manufacturing technology [Madou 2001] Microfluidics ... platforms without denaturing the preloaded proteins and contaminating the microfluidic channels 1.3 Outline Chapter contains a comprehensive literature review of microfabrication and and microfluidics...
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Development of computational methods for the rapid determination of NMR resonance assignment of large proteins
... determination is the spectral assignment procedure This involves sequence-specific resonance assignment of NMR signals and the assignment of NOESY spectra Resonance assignment forms the basis for characterizing ... obtain the assignments of the Cα and CO of the same residue Then, the CO frequency is used to obtain assignments for the HN and 15N of residue (i+1) with the HNCO experiment Finally, the NH and ... applications for solution NMR 1.3.2 TROSY triple -resonance experiments for resonance assignments of large proteins NMR experiments provide a set of unique combinations of neighboring resonance spin...
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Development of the Quantitative PCR Method for Candidatus ‘Accumulibacter phosphatis’ and Its Application to Activated Sludge
... archaebacteria Candidatus ‘Accumulibacter phosphatis’ Candidatus ‘Accumulibacter phosphatis’ Candidatus ‘Accumulibacter phosphatis’ Candidatus ‘Accumulibacter phosphatis’ Candidatus ‘Accumulibacter phosphatis’ ... Quantitative PCR and FISH method in Activated sludge The amount of Candidatus ‘Accumulibacter phosphatis’ in the laboratory-scale and the full-scale activated sludge were quantified both by the quantitative ... abundance in activated sludge Nevertheless, quantitative PCR method for Candidatus ‘Accumulibacter phosphatis’ has not been developed yet In this study, quantitative PCR method for Candidatus ‘Accumulibacter...
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Báo cáo hóa học: " On the understanding and development of modern physical neurorehabilitation methods: robotics and non-invasive brain stimulation" pdf
... recovery and plasticity with brain stimulation? One of the contemporary methods under investigation as a tool to promote neuroplasticity is non-invasive brain stimulation The concept of treating ... This was based on the understanding of neurological dysfunction at the time, and the observation that patients appeared to tolerate and benefit from physical interventions Observations that patients ... community concerning the benefit of various types of physical therapies Evolution of physical rehabilitation Historically, the management of stroke survivors involved bed-rest and convalescence,...
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báo cáo hóa học: " TLR3 signaling is either protective or pathogenic for the development of Theiler''''s virus-induced demyelinating disease depending on the time of viral infection" docx
... TLR3 signaling is either protective or pathogenic for the development of Theiler’s virus-induced demyelinating disease depending on the time of viral infection Young-Hee Jin1, ... strongly warrant caution on the use of TLR3- mediated immune interventions against chronic viral diseases and suggest careful consideration for these treatments in conjunction with the time of viral ... particularly around the onset of disease development (28 dpi) These results strongly suggest that activation of TLR3 signaling prior to viral infection hinders the induction of protective IFN-γ-producing...
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Báo cáo toán học: " Strong convergence theorems and rate of convergence of multi-step iterative methods for continuous mappings on an arbitrary interval" pptx
... Strong convergence theorems and rate of convergence of multi-step iterative methods for continuous mappings on an arbitrary interval Withun Phuengrattana1,2 and Suthep Suantai1,2,∗ ... employ the concept of W -mappings and Kmappings for approximation of a solution of (1.2) for a continuous function on an arbitrary interval and compare which one converges faster The concept of W -mapping ... iteration converges faster than the Mann iteration for the class of continuous and nondecreasing functions Later in 1991, Borwein and Borwein [6] proved the convergence of the Mann iteration of continuous...
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Báo cáo hóa học: " Research Article An Application of Hybrid Steepest Descent Methods for Equilibrium Problems and Strict Pseudocontractions in Hilbert Spaces" pdf
... of Inequalities and Applications 15 L.-C Ceng, S Al-Homidan, Q H Ansari, and J.-C Yao, An iterative scheme for equilibrium problems and fixed point problems of strict pseudo-contraction mappings,” ... Springer, Berlin, Germany, 1999 S Plubtieng and R Punpaeng, “A general iterative method for equilibrium problems and fixed point problems in Hilbert spaces,” Journal of Mathematical Analysis and ... “Construction of fixed points of nonlinear mappings in Hilbert space,” Journal of Mathematical Analysis and Applications, vol 20, pp 197–228, 1967 15 S.-S Chang, “Some problems and results in the study of...
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báo cáo hóa học:" Strong convergence theorems and rate of convergence of multi-step iterative methods for continuous mappings on an arbitrary interval" pdf
... Strong convergence theorems and rate of convergence of multi-step iterative methods for continuous mappings on an arbitrary interval Withun Phuengrattana1,2 and Suthep Suantai1,2,∗ ... employ the concept of W -mappings and Kmappings for approximation of a solution of (1.2) for a continuous function on an arbitrary interval and compare which one converges faster The concept of W -mapping ... iteration converges faster than the Mann iteration for the class of continuous and nondecreasing functions Later in 1991, Borwein and Borwein [6] proved the convergence of the Mann iteration of continuous...
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Báo cáo hóa học: " Research Article Sequential Monte Carlo Methods for Joint Detection and Tracking of Multiaspect Targets in Infrared Radar Images" pptx
... Godsill, and J Vermaak, “Multitarget tracking using a new soft-gating approach and sequential Monte Carlo methods, ” in Proceedings of the IEEE International Conference on Acoustics, Speech, and Signal ... p = 000 particles Figure shows the actual CONCLUSIONS AND FUTURE WORK We discussed in this paper a methodology for joint detection and tracking of multiaspect targets in remote sensing image ... F G Freitas, and N J Gordon, “An introduction to sequential Monte Carlo methods, ” in Sequential Monte Carlo Methods in Practice, A Doucet, N F G Freitas, and N J Gordon, Eds., Springer, New York,...
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Báo cáo hóa học: " Research Article Computational Methods for Estimation of Cell Cycle Phase Distributions of Yeast Cells" docx
... percent of cells in cell cycle phases G1, S, and G2/M, respectively In this section, we present two computational methods for estimation of the cell cycle phase distribution of a yeast cell population ... Number of cells 250 Number of cells 250 200 Number of cells 250 150 100 50 0.2 0.4 0.6 0.8 150 100 50 0.2 Cell cycle phase 0.4 0.6 0.8 0.2 Cell cycle phase (a) 0.4 0.6 0.8 Cell cycle phase (b) ... good estimate for the S phase of the cell cycle with this approach [9] The phase of the cell cycle depends by definition on the amount of DNA in the cell Cells that are in the G1 phase have the...
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Từ khóa: design and development of self emulsifying lipid formulations for improving oral bioavailability of poorly water soluble and lipophilic drugsdevelopment of a rapid screening procedure for growth and lipid content of microalgaediscovery and development of maraviroc and pf 232798 ccr5 antagonists for the treatment of hiv 1 infectioncurrent environment for the development of prognostic and predictive laboratory testssimple methods for the detection of hla g variants in coding and non coding regionsleveraging structural information for the discovery of new drugs computational methodsdevelopment of health and sustainability indicators for a tropical highlands agroecosystemthe development of oral and written languagedevelopment of embryo and fetus picturesdevelopment of embryo and fetus ppthistorical development of research and theory in nursingdevelopment of theory and research in nursingexplain how play activities are used to support development of speech and languagethe development of oral and written language in social contextsdevelopment of hematopoietic and vascular cellsBáo cáo quy trình mua hàng CT CP Công Nghệ NPVNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngNghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000Định tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Tranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)chuong 1 tong quan quan tri rui roGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtBÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIĐổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namTÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ