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Báo cáo y học: "Systems biology-defined NF-κB regulons, interacting signal pathways and networks are implicated in the malignant phenotype of head and neck cancer cell lines differing in p53 status" pps

Báo cáo y học:

Báo cáo y học: "Systems biology-defined NF-κB regulons, interacting signal pathways and networks are implicated in the malignant phenotype of head and neck cancer cell lines differing in p53 status" pps

... Access2008Yanet al.Volume 9, Issue 3, Article R53ResearchSystems biology-defined NF-κB regulons, interacting signal pathways and networks are implicated in the malignant phenotype of head and neck ... domi-nantly associated with components of the neuregulin signal- ing pathway (the third row). In the remaining signaling and functional pathways, with the exception of cell cycle:G2/Mcheckpoint components, ... expression,coordinating action within networks and pathways that con-tribute to the malignant phenotype of UM-SCC. Our studyrevealed the power of a systems biology analysis usingCOGRIM modeling and IPA...
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Báo cáo y học: " Infection with hepatitis B virus carrying novel pre-S/S gene mutations in female siblings vaccinated at birth: two case reports" pot

... of this journal.Competing interests The authors declare that they have no competing interests.Authors' contributionsMWL, CSHY and CTY analyzed and interpreted the sequence data. MWL and CSHY ... S-H Yeh3 and Chau-Ting Yeh*2,3AbstractIntroduction: After the initiation of a mass hepatitis B vaccination program in Taiwan, the prevalence of hepatitis B virus infection has declined ... mutations in the S gene near the "a" determinant region in the elder sister and a novel pre-S2 deletion in the younger sister.ConsentWritten informed consent was obtained from the motheron...
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Báo cáo Y học: Early growth response-1 gene (Egr-1 ) promoter induction by ionizing radiation in U87 malignant glioma cells in vitro pot

Báo cáo Y học: Early growth response-1 gene (Egr-1 ) promoter induction by ionizing radiation in U87 malignant glioma cells in vitro pot

... Rodemann11Section of Radiobiology and Molecular Environmental Research, Department of Radiotherapy, and 2Department of MolecularPathology, University of TuÈbingen, Germany The promoter of the early growth ... obtained afterirradiating cells with UV light are in perfect agreement with the immunoblot analyses and suramin inhibition experi-ments presented in our study indicating an auto- and/ orparacrine ... in the media of 100 nM. As a speci®c inhibitor o f phosphat-idylinositol 3-kinase (PtdIns3-kinase, IC50 5nM)wort-mannin a llows us to investigate d o wnstream signalling of the P tdIns3...
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Báo cáo y học: "A web tool for finding gene candidates associated with experimentally induced arthritis in the rat" docx

... selecting and ranking keywords, and searching OMIM text for selected keywords.Finding a QTL of interest The first step in finding candidate genes for a specific QTL isto choose a QTL of interest. ... thatmost of the points come from the part of the text describingthese particular findings. To evaluate the ability of the tool topredict genes that are reported to be related to the arthritis phenotype, ... textinvestigated. In the paper describing Olofsson's findings, the authors stated that they found the candidate gene approachdistracting, even though they were facing a region that con-tained...
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Báo cáo y học: " Pro/Con Debate: Does recombinant factor VIIa have a role to play in the treatment of patients with acute nontraumatic hemorrhage" ppt

... although the patient is in extremis, the potentially life-saving benefit of correcting the patient’s coagulopathy and ceasing his hemorrhage clearlytakes precedent. Furthermore, the only other option ... without any evidence for the drug’sefficacy and safety. The first issue is the off-label use. After a single successfulreport of off-label use of recombinant FVIIa (rFVIIa) in 1999,many physicians ... Therefore, off-label use of FVIIa in this setting is not onlywarranted but also potentially beneficial and life saving.Con: Recombinant FVIIa is not a cure for all bleedingSandro Scarpelini and Sandro...
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Báo cáo y học: "HTLV-1 Tax mutants that do not induce G1 arrest are disabled in activating the anaphase promoting complex" pdf

... activation of the anaphase promoting complex and the premature deg-radation of mitotic /cell cycle regulators including cyclinA, Clb2/cyclin B, Pds1/securin, and Skp2 [30]. The levels of cyclin B1, ... the levels of cyclin B1 in the respec-tive cell lines inversely correlated with the growth charac-teristics of the respective cells. Likewise, the levels of Skp2 in the transduced cells also ... not involve directly either the CREB/CBP/p300 or the IKK /NF-κB pathway. Whether the IKK /NF-κB pathway may share a common Tax-targetedregulatory factor with the cell cycle/APC pathway remainsto...
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báo cáo sinh học:

báo cáo sinh học:" Training health care workers to promote HIV services for patients with tuberculosis in the Democratic Republic of Congo" pptx

... TB and HIVProgram staff in the development phase facilitated the use of the training materials by the National Program in the roll-out of TB/HIV training for HCWs involved in TB care in the ... counseling and testing in the TB clinic, care for HIV co-infected TB patients, and moni-toring and evaluation of HIV activities, including the use of a modified TB treatment card. Training on the ... train-ing for the TB health care workers and helped with itsdevelopment. WD and FB also helped with developing the training. AVR conceived of the study, participated in developing the training,...
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Báo cáo y học: " Concerns regarding hepatitis B vaccination and post-vaccination test among Brazilian dentists" pps

... and whether the dentists' clinical dental chart contains a question on a his-tory of hepatitis.As individuals may go to school at any time in theirlives and the number of years of professional ... and the United Kingdom [17-23]. The results of the present study reveal that an average of 73.8% of the dentists had taken the three doses of the hepatitis B vaccine. The Brazilian Ministry of ... withexposure factors, such as the use of piercing and tattoos,history of any kind of transplant, dialysis, colonoscopy and chemotherapy.2- Professional, behavioural and occupational exposure dataWork...
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Báo cáo y học:

Báo cáo y học: " Systems-level comparison of host responses induced by pandemic and seasonal influenza A H1N1 viruses in primary human type I-like alveolar epithelial cells in vitro" pdf

... f cytokine responses in humanmacrophages and epithelial cells [2-4]. This suggeststhat the c ytokine dysregulation seen in H5N1 infectionis not an intrinsic feature of the pdmH1N1 virus. The ... was handled in a bio-safetylevel 3 facility at the D epartm ent of Microbiolo gy, The University of Hong Kong.Isolation of primary human alveolar type II alveolarepithelial cellsPrimary type ... DM: The pathology of influenza virus infections.Annual Review of Pathology 2008, 3:499-522.26. Woo PC, Tung ET, Chan KH, Lau CC, Lau SK, Yuen KY: Cytokine profilesinduced by the novel swine-origin...
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Báo cáo y học: " Systems biology coupled with label-free high-throughput detection as a novel approach for diagnosis of chronic obstructive pulmonary disease" pptx

... The latter point is extremely important ifcommunity screening is to be employed. Similarly, Baye-sian approaches are not the only ways forward in mining the profile information. Other groups ... previouslyassociated with the disease of interest. As such, they willbe vital during the extremely complex task of identifying and revising disease-specific molecular fingerprints.Systems Biology: ... spirometric interpretive skills [26]. Addition- The main methods currently used by clinicians to classify the severity of COPDFigure 1 The main methods currently used by clinicians to classify the severity...
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