... administration resulted in a significantenhancement in leucocyte–EC interaction, as indicated bytransiently increased number of leucocytes firmly attaching tothe microvascular endothelium of arterioles ... antifibrinolysis. LPS, lipopolysaccharide; M,activated monocyte; SMC, smooth muscle cell; TF, tissue factor; TM,thrombomodulin.ECSMCMPAIAntifibrinolysis CoagulationLPS,LPS,cytokines cytokines ... binding, which in turn facilitatesrolling. Selectins allow leucocytes to roll in the direction of flow into the proximity of activating signals exhibited by ECs.The second step involves receptors...